{
    "abstract": "Real-time evaluation of blood perfusion is important when selecting the site of anastomosis during thoracic esophagectomy. This study investigated a novel imaging technology that assesses tissue oxygen saturation (StO2) in the gastric conduit and examined its efficacy.\nFifty-one patients undergoing thoracic esophagectomy for esophageal cancer who underwent intraoperative StO2 endoscopic imaging to assess the gastric conduit for the optimal site of anastomosis were examined. Efficacy of oxygen saturation imaging and patient outcomes were analyzed.\nAll 51 patients underwent esophagectomy without intraoperative problems. Mean StO2 in the gastric tube was highest at the pre-pylorus area and then gradually decreased proceeding toward the tip. StO2 was well preserved in areas supplied by the right gastroepiploic artery but low in other areas. Anastomotic sites were selected based on StO2 imaging and tension considerations; most were located within 3\u00a0cm of the end of the right gastroepiploic artery. Three patients developed postoperative anastomotic leakage (5.8%). Mean StO2 at the point of anastomosis was significantly lower in the patients who experienced leakage than in those who did not (P\u2009=\u20090.04).\nIntraoperative endoscopic StO2 imaging is useful in esophageal cancer patients undergoing thoracic esophagectomy to determine the optimal site for anastomosis to minimize the risk of anastomotic leakage.",
    "authors": [
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. takfujit@east.ncc.go.jp.",
            "firstname": "Takeo",
            "initials": "T",
            "lastname": "Fujita"
        },
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.",
            "firstname": "Kazuma",
            "initials": "K",
            "lastname": "Sato"
        },
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.",
            "firstname": "Asasko",
            "initials": "A",
            "lastname": "Ozaki"
        },
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.",
            "firstname": "Akutsu",
            "initials": "A",
            "lastname": "Tomohiro"
        },
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.",
            "firstname": "Takuji",
            "initials": "T",
            "lastname": "Sato"
        },
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.",
            "firstname": "Yuki",
            "initials": "Y",
            "lastname": "Hirano"
        },
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.",
            "firstname": "Hisashi",
            "initials": "H",
            "lastname": "Fujiwara"
        },
        {
            "affiliation": "Division of Gastrointestinal Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan.",
            "firstname": "Yusuke",
            "initials": "Y",
            "lastname": "Yoda"
        },
        {
            "affiliation": "Division of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.",
            "firstname": "Takashi",
            "initials": "T",
            "lastname": "Kojima"
        },
        {
            "affiliation": "Division of Gastrointestinal Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan.",
            "firstname": "Tomonori",
            "initials": "T",
            "lastname": "Yano"
        },
        {
            "affiliation": "Division of Esophageal Surgery, National Cancer Center Hospital, Tokyo, Japan.",
            "firstname": "Hiroyuki",
            "initials": "H",
            "lastname": "Daiko"
        }
    ],
    "conclusions": "Intraoperative endoscopic StO2 imaging is useful in esophageal cancer patients undergoing thoracic esophagectomy to determine the optimal site for anastomosis to minimize the risk of anastomotic leakage.",
    "copyrights": "\u00a9 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
    "doi": "10.1007/s00464-022-09199-6\n10.1016/j.ejso.2012.07.111\n10.1001/2013.jamasurg.2\n10.1097/DCR.0000000000001123\n10.1007/s00464-018-6503-7\n10.1371/journal.pone.0099055\n10.1117/1.JBO.20.12.126011\n10.1186/s12893-020-00913-6\n10.1007/s00595-018-1752-6\n10.1097/SLA.0b013e3181b13ca2\n10.1007/s00464-005-0388-y\n10.1016/j.ejso.2020.09.032\n10.1097/SLA.0000000000001828\n10.1007/s11605-018-3857-z\n10.1097/SLA.0000000000001011\n10.1016/j.athoracsur.2020.08.022\n10.1097/SLA.0b013e3181deb4b7\n10.1007/s00423-006-0067-z\n10.1016/j.wneu.2019.09.135\n10.7326/0003-4819-109-4-345_2\n10.1093/dote/doaa100\n10.4251/wjgo.v11.i3.250",
    "journal": "Surgical endoscopy",
    "keywords": [
        "Esophagectomy",
        "Gastric conduit",
        "Oxygen saturation imaging"
    ],
    "methods": null,
    "publication_date": "2022-04-03",
    "pubmed_id": "35364701\n33016305",
    "results": "All 51 patients underwent esophagectomy without intraoperative problems. Mean StO2 in the gastric tube was highest at the pre-pylorus area and then gradually decreased proceeding toward the tip. StO2 was well preserved in areas supplied by the right gastroepiploic artery but low in other areas. Anastomotic sites were selected based on StO2 imaging and tension considerations; most were located within 3\u00a0cm of the end of the right gastroepiploic artery. Three patients developed postoperative anastomotic leakage (5.8%). Mean StO2 at the point of anastomosis was significantly lower in the patients who experienced leakage than in those who did not (P\u2009=\u20090.04).",
    "title": "A novel imaging technology to assess oxygen saturation of the gastric conduit in thoracic esophagectomy.",
    "xml": "<Element 'PubmedArticle' at 0x7885025881d0>"
}