{
    "abstract": "In patients with severe acute respiratory distress syndrome (ARDS), prolonged and inappropriate use of prone position ventilation (PPV) is a known risk factor for mortality. Hence, it is critical to monitor patients' response to PPV and accurately differentiate responders from non-responders at an early stage. The study aimed to investigate the relationship between oxygenation improvement after three rounds of PPV and survival rate in patients with pulmonary ARDS. Additionally, we sought to identify the earliest turning point for escalation from PPV to extracorporeal membrane oxygenation.\nWe performed a retrospective observational study from 2015 to 2023. We included adult patients who received invasive mechanical ventilation, underwent at least three periods of at least 6\u00a0h of PPV after admission to the Intensive Care Unit, and meet the ARDS criteria. The study collected data on each PPV session, including changes in PaCO\nA total of 104 patients were enrolled in the study. The change in PaCO\nThe percentage change in PaO",
    "authors": [
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.\nGuangzhou Blood Center, 31 Luyuan Road, Yuexiu District, Guangzhou, Guangdong, 510095, China.",
            "firstname": "Hanwen",
            "initials": "H",
            "lastname": "Liang"
        },
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.\nDepartment of Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.",
            "firstname": "Qiuxue",
            "initials": "Q",
            "lastname": "Deng"
        },
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.\nDepartment of Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.",
            "firstname": "Weiyan",
            "initials": "W",
            "lastname": "Ye"
        },
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.\nDepartment of Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.",
            "firstname": "Zhenjie",
            "initials": "Z",
            "lastname": "Jiang"
        },
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.\nDepartment of Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.",
            "firstname": "Baozhu",
            "initials": "B",
            "lastname": "Zhang"
        },
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.\nDepartment of Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China.",
            "firstname": "Jiesen",
            "initials": "J",
            "lastname": "Zhang"
        },
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China. jiangmei927@163.com.",
            "firstname": "Mei",
            "initials": "M",
            "lastname": "Jiang"
        },
        {
            "affiliation": "National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China. xuyuanda@sina.com.\nDepartment of Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong, 510120, China. xuyuanda@sina.com.",
            "firstname": "Yuanda",
            "initials": "Y",
            "lastname": "Xu"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2024. The Author(s).",
    "doi": "10.1186/s12890-024-03349-3",
    "journal": "BMC pulmonary medicine",
    "keywords": [
        "Acute respiratory distress syndrome",
        "Oxygenation",
        "Prone position",
        "Responders",
        "Ventilation"
    ],
    "methods": null,
    "publication_date": "2024-11-21",
    "pubmed_id": "39567964\n20693377\n21997128\n26903337\n32648899\n33976229\n33247138\n35698155\n33159154\n32250385\n32242947\n32007143\n31197492\n28459336\n29218379\n33823862\n23688302\n19903918\n24134414\n31144997\n36343687\n35200196\n11497137\n33003079\n35216579\n26806842\n24528322\n14668608\n34582426\n35349967\n24132038\n35294565\n18064739\n22797452\n35753956\n30908313\n27400909\n11529210\n7956412\n9032181\n35195460\n8942587\n15547166\n21791044\n9476848\n33169218\n34259655\n34461971\n24377654\n29554187\n20179008\n28108768\n33406012\n36239747",
    "results": "A total of 104 patients were enrolled in the study. The change in PaCO",
    "title": "Prone position ventilation-induced oxygenation improvement as a valuable predictor of survival in patients with acute respiratory distress syndrome: a retrospective observational study.",
    "xml": "<Element 'PubmedArticle' at 0x788505ac9990>"
}