{
    "abstract": "We studied the incidence and risk factors of acute kidney injury (AKI) following coronary angiography (CA) and examined short- and long-term outcomes of patients who developed AKI, including progression of chronic kidney disease (CKD).\nThis was a retrospective study of all patients undergoing CA in Iceland from 2008 to 2015, with or without percutaneous coronary intervention. All procedures were performed with iso-osmolar contrast. AKI was defined according to the SCr component of the KDIGO criteria. Patients without post-procedural SCr were assumed to be free of AKI. Incident CKD was defined as 90-day sustained estimated glomerular filtration rate (eGFR)\u2009<\u200960\u00a0mL/min/1.73\u00a0m\nAKI was detected in 231 of 13,561 cases (1.7%). There was an interaction between contrast dose and preexisting kidney function, where the risk for AKI was only significant at a dose\u2009>\u2009150\u00a0mL in patients with baseline eGFR\u2009<\u200945\u00a0mL/min/1.73\u00a0m\nFor iso-osmolar contrast, the risk of AKI related to contrast dose was evident for higher amount of contrast in patients with baseline eGFR\u2009<\u200945\u00a0mL/min/1.73\u00a0m",
    "authors": [
        {
            "affiliation": "Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nFaculty of Medicine, University of Iceland, Reykjavik, Iceland.",
            "firstname": "Dadi",
            "initials": "D",
            "lastname": "Helgason"
        },
        {
            "affiliation": "Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nFaculty of Medicine, University of Iceland, Reykjavik, Iceland.",
            "firstname": "Thorir E",
            "initials": "TE",
            "lastname": "Long"
        },
        {
            "affiliation": "Division of Anaesthesia and Intensive Care Medicine, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.",
            "firstname": "Solveig",
            "initials": "S",
            "lastname": "Helgadottir"
        },
        {
            "affiliation": "Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nDivision of Nephrology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nFaculty of Medicine, University of Iceland, Reykjavik, Iceland.",
            "firstname": "Runolfur",
            "initials": "R",
            "lastname": "Palsson"
        },
        {
            "affiliation": "Division of Anaesthesia and Intensive Care Medicine, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nFaculty of Medicine, University of Iceland, Reykjavik, Iceland.",
            "firstname": "Gisli H",
            "initials": "GH",
            "lastname": "Sigurdsson"
        },
        {
            "affiliation": "Division of Cardiothoracic Surgery, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nFaculty of Medicine, University of Iceland, Reykjavik, Iceland.",
            "firstname": "Tomas",
            "initials": "T",
            "lastname": "Gudbjartsson"
        },
        {
            "affiliation": "Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nDivision of Nephrology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.",
            "firstname": "Olafur S",
            "initials": "OS",
            "lastname": "Indridason"
        },
        {
            "affiliation": "Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.\nDivision of Cardiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.",
            "firstname": "Ingibjorg J",
            "initials": "IJ",
            "lastname": "Gudmundsdottir"
        },
        {
            "affiliation": "Division of Anaesthesia and Intensive Care Medicine, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland. martiningi@gmail.com.\nDepartment of Anesthesiology, Duke University Hospital, 2301 Erwin Road, Durham, NC, USA. martiningi@gmail.com.",
            "firstname": "Martin I",
            "initials": "MI",
            "lastname": "Sigurdsson"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1007/s40620-018-0534-y\n10.1016/j.jacc.2007.12.035\n10.1016/j.jacc.2016.05.099\n10.1148/radiol.12120044\n10.1002/ccd.26106\n10.1148/radiol.12121823\n10.1177/2048872617708975\n10.1161/circinterventions.116.004439\n10.1161/circinterventions.112.974493\n10.1161/circulationaha.110.970160\n10.1016/j.jacc.2013.01.007\n10.1097/00005650-199801000-00004\n10.1016/0002-9149(67)90023-9\n10.7326/0003-4819-150-9-200905050-00006\n10.1161/circulationaha.110.953851\n10.1007/s40620-017-0461-3\n10.1111/j.1540-8183.2010.00581.x\n10.1001/jamacardio.2017.2156\n10.1016/j.jacc.2004.06.068\n10.1007/s40620-018-0498-y\n10.1007/s40620-015-0255-4\n10.1186/cc6863\n10.1136/bmj.h4395\n10.1159/000430472\n10.1530/eje-13-1020\n10.1111/jch.12795\n10.1093/ndt/gfv023\n10.1016/j.amjmed.2014.05.011\n10.1016/j.jacc.2007.03.058\n10.1161/circinterventions.109.910638\n10.1093/ndt/gfs602\n10.1002/ccd.21619\n10.1161/circulationaha.111.085290\n10.1038/ki.2011.379\n10.1152/ajprenal.00050.2001\n10.1038/ki.2010.258\n10.1161/jaha.116.003812",
    "journal": "Journal of nephrology",
    "keywords": [
        "Acute kidney injury",
        "Chronic kidney disease",
        "Contrast",
        "Coronary angiography",
        "Survival"
    ],
    "methods": null,
    "publication_date": "2018-09-07",
    "pubmed_id": "30187381\n18402894\n27659469\n23023964\n26481591\n23360742\n28607001\n23322741\n21242477\n23500325\n9431328\n6059183\n19414839\n21135373\n29185210\n20796168\n28678988\n15464318\n29802583\n26861658\n18402655\n26316642\n24569125\n24852935\n17692741\n20587788\n18729173\n22592896\n22113526\n20686453\n27742616",
    "results": "AKI was detected in 231 of 13,561 cases (1.7%). There was an interaction between contrast dose and preexisting kidney function, where the risk for AKI was only significant at a dose\u2009>\u2009150\u00a0mL in patients with baseline eGFR\u2009<\u200945\u00a0mL/min/1.73\u00a0m",
    "title": "Acute kidney injury following coronary angiography: a nationwide study of incidence, risk factors and long-term outcomes.",
    "xml": "<Element 'PubmedArticle' at 0x788505992a20>"
}