{
    "abstract": "Placenta accreta spectrum disorders (PAS), a devastating obstetric complication, has increased dramatically in recent decades along with the growing rate of cesarean worldwide. Various conservative management techniques, aimed to avoid hysterectomy and potentially preserve fertility, have been implemented in the management of PAS. However, reports on subsequent pregnancy outcomes following conservative management for PAS are limited.\nTo systematically evaluate the subsequent pregnancy outcomes in PAS patients undergoing conservative management.\nThis was a single-center, ambispective cohort study conducted between January 2013 to March 2021. Follow-ups were conducted annually, extending until March 2023. Eligible patients were PAS patients who underwent successful conservative treatment and had intentions for future fertility. Baseline characteristics, conservative management strategies, and subsequent pregnancy outcomes were collected and analyzed. Primary outcome was the subsequent pregnancy outcomes, including interpregnancy interval, conceive method, pregnancy success rate, pregnancy and delivery outcomes, and major maternal morbidities.\nA total of 40 patients with conservatively managed PAS and attempting subsequent pregnancies were included. These patients were further divided into the subsequent pregnancy group (\nOur findings reveal that while conservative management for PAS does not compromise subsequent fertility, it does pose substantial risks in subsequent pregnancies, including high recurrence rates of PAS, significant PPH, and increased incidence of composite adverse delivery outcomes. Patients should be thoroughly informed of the related risks and subsequent pregnancies necessitate comprehensive preconception counseling, meticulous antenatal care and individualized management strategies to minimize these risks.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.\nDepartment of Obstetrics and Gynecology, People's Hospital Affiliated to Shandong First Medical University, Jinan, China.",
            "firstname": "Kai",
            "initials": "K",
            "lastname": "Chen"
        },
        {
            "affiliation": "Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.",
            "firstname": "Yulu",
            "initials": "Y",
            "lastname": "Bai"
        },
        {
            "affiliation": "Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.",
            "firstname": "Youliang",
            "initials": "Y",
            "lastname": "Ma"
        },
        {
            "affiliation": "Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.",
            "firstname": "Junyao",
            "initials": "J",
            "lastname": "Chen"
        },
        {
            "affiliation": "Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.",
            "firstname": "Yan",
            "initials": "Y",
            "lastname": "Huang"
        },
        {
            "affiliation": "Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.",
            "firstname": "Fang",
            "initials": "F",
            "lastname": "Yang"
        },
        {
            "affiliation": "Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.\nMedical Simulation Center, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.",
            "firstname": "Yu",
            "initials": "Y",
            "lastname": "Long"
        }
    ],
    "conclusions": "Our findings reveal that while conservative management for PAS does not compromise subsequent fertility, it does pose substantial risks in subsequent pregnancies, including high recurrence rates of PAS, significant PPH, and increased incidence of composite adverse delivery outcomes. Patients should be thoroughly informed of the related risks and subsequent pregnancies necessitate comprehensive preconception counseling, meticulous antenatal care and individualized management strategies to minimize these risks.",
    "copyrights": null,
    "doi": "10.1080/14767058.2025.2477782",
    "journal": "The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians",
    "keywords": [
        "PAS recurrence",
        "Placenta accreta spectrum disorders",
        "conservative management",
        "risk",
        "subsequent pregnancy outcomes"
    ],
    "methods": null,
    "publication_date": "2025-03-17",
    "pubmed_id": "40091419",
    "results": "A total of 40 patients with conservatively managed PAS and attempting subsequent pregnancies were included. These patients were further divided into the subsequent pregnancy group (",
    "title": "Subsequent pregnancy outcomes following conservative management for placenta accreta spectrum disorders: an ambispective cohort study.",
    "xml": "<Element 'PubmedArticle' at 0x788505ca78d0>"
}