{
    "abstract": "Pediatric cochlear implant (CI) recipients with cochlear malformations face challenges due to variable speech recognition outcomes.\nThis study assesses the predictive value of intraoperative electrically evoked compound action potential (eCAP) thresholds, residual hearing, age at implantation, Intelligent Quotient (IQ), and malformation type for speech recognition outcomes.\nA prospective cohort of 52 children (aged 1-4\u2009years) with cochlear malformations who underwent CI between 2016 and 2024 was analyzed. Intraoperative eCAP thresholds were recorded, and disyllable word recognition scores (WRS) were evaluated 24\u2009months postoperatively.\nPatients included incomplete partition (IP-II, 46.2%), cochlear hypoplasia (30.8%), IP-I (13.5%), and common cavity (9.6%). IP-II cases had higher mean eCAP thresholds (18.85\u2009\u00b5V) compared to cochlear hypoplasia and common cavity cases. Higher eCAP thresholds correlated with better WRS outcomes (\nIntraoperative eCAP thresholds and residual hearing strongly predict auditory outcomes in children with cochlear malformations. Tailored CI strategies based on individual profiles can optimize speech recognition outcomes.",
    "authors": [
        {
            "affiliation": "PDCC-Neuro-Otology, Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Das K",
            "initials": "DK",
            "lastname": "Nidhin"
        },
        {
            "affiliation": "Neuro-Otology, Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Amit",
            "initials": "A",
            "lastname": "Keshri"
        },
        {
            "affiliation": "Neuro-Otology, Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Ravisankar",
            "initials": "R",
            "lastname": "Manogaran"
        },
        {
            "affiliation": "Neuro-Otology, Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Nazrin",
            "initials": "N",
            "lastname": "Hameed"
        },
        {
            "affiliation": "Department of Biostatistics and Health Informatics, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Prabhakar",
            "initials": "P",
            "lastname": "Mishra"
        },
        {
            "affiliation": "Neuro-Otology, Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Mohd",
            "initials": "M",
            "lastname": "Aqib"
        },
        {
            "affiliation": "Neuro-Otology, Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Kalyan",
            "initials": "K",
            "lastname": "Chidambaram"
        },
        {
            "affiliation": "Neuro-Otology, Department of Neurosurgery, SGPGIMS, Lucknow, Uttar Pradesh, India.",
            "firstname": "Mohit",
            "initials": "M",
            "lastname": "Sinha"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1080/00016489.2024.2449251",
    "journal": "Acta oto-laryngologica",
    "keywords": [
        "ECAP thresholds",
        "cochlear implants",
        "cochlear malformations",
        "speech outcome"
    ],
    "methods": null,
    "publication_date": "2025-01-16",
    "pubmed_id": "39817832",
    "results": "Patients included incomplete partition (IP-II, 46.2%), cochlear hypoplasia (30.8%), IP-I (13.5%), and common cavity (9.6%). IP-II cases had higher mean eCAP thresholds (18.85\u2009\u00b5V) compared to cochlear hypoplasia and common cavity cases. Higher eCAP thresholds correlated with better WRS outcomes (",
    "title": "Leveraging eCAP thresholds in a logistic model to predict speech outcomes after implantation in anomalous cochlea.",
    "xml": "<Element 'PubmedArticle' at 0x78850424f970>"
}