{
    "abstract": "Treatment of femoral neck fractures secondary to osteopetrosis is an uncertain and puzzled decision. Experience in the treatment, especially in the pediatric population, is scarcely reported. The duration of conservative treatment is prolonged and poses the risks of non-union and development of coxa vara deformity. The recommended treatment is closed reduction and internal fixation; however, surgery on osteopetrotic bone is challenging due to defective bone marrow function, delayed consolidation and higher risk of intraoperative fractures. Slipped capital femoral epiphysis secondary to osteopetrosis is very rarely reported. This article presents the case of a\u00a05-year-old female patient with rapidly deteriorating physical function due to bilateral proximal femoral Salter-Harris type\u00a0II fractures with associated slippage of the growth plates secondary to confirmed autosomal recessive osteopetrosis. Operative treatment was performed in a\u00a0tertiary level orthopedic center with closed reduction and internal fixation with cannulated screws. A\u00a0loss of fixation with coxa vara deformity was seen on the left side 7\u00a0months postoperatively with increasing pain. A\u00a0revision surgery with reosteosynthesis and a\u00a0valgus osteotomy was thus performed which showed good subjective and objective results 1\u00a0year postoperatively with complete bony union.\nDie Behandlung von Schenkelhalsfrakturen als Folge einer Osteopetrose ist eine Herausforderung. Erfahrungen mit der Behandlung, insbesondere bei Kindern und Jugendlichen, liegen kaum vor. Die Dauer der konservativen Therapie ist verl\u00e4ngert und birgt das Risiko einer Pseudarthrose und der Entwicklung einer Coxa-vara-Deformit\u00e4t. Die empfohlene Behandlung ist eine geschlossene Reposition und interne Fixation. Die osteopetrotischen Knochen sind jedoch aufgrund der defekten Knochenmarkfunktion, der verz\u00f6gerten Konsolidierung und des h\u00f6heren Risikos f\u00fcr intraoperative Frakturen eine Herausforderung. Sehr selten wird \u00fcber eine Epiphyseolysis capitis femoris bei Osteopetrose berichtet. Dieser Fall stellt eine 5\u2011j\u00e4hrige Patientin mit rasch nachlassender k\u00f6rperlicher Funktionsf\u00e4higkeit aufgrund einer bilateralen Salter-Harris-II-Fraktur mit beidseitiger Epiphyseolysis capitis femoris als Folge einer best\u00e4tigten autosomal-rezessiven Osteopetrose vor. Die operative Behandlung wurde in einem Universit\u00e4tsklinikum durchgef\u00fchrt mit geschlossener Reposition und interner Fixation mit kannelierten Schrauben. Sieben Monate postoperativ zeigte sich auf der linken Seite ein Fixationsverlust mit Coxa vara und zunehmenden Schmerzen. Daher wurde eine Revisionsoperation mit Reosteosynthese und einer Valgisierungsosteotomie durchgef\u00fchrt, die 1\u00a0Jahr postoperativ gute subjektive und objektive Ergebnisse mit einer vollst\u00e4ndigen Knochenheilung zeigte.",
    "authors": [
        {
            "affiliation": "Department of Orthopedics and Trauma Surgery, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstr. 200a, 69118, Heidelberg, Germany. ayham.jaber@med.uni-heidelberg.de.",
            "firstname": "Ayham",
            "initials": "A",
            "lastname": "Jaber"
        },
        {
            "affiliation": "Department of Orthopedics and Trauma Surgery, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstr. 200a, 69118, Heidelberg, Germany.",
            "firstname": "Martin",
            "initials": "M",
            "lastname": "Schwarze"
        },
        {
            "affiliation": "Department of Diagnostic and interventional Radiology, Heidelberg University Hospital, Im Neuenheimer Feld\u00a0420, 69120, Heidelberg, Germany.",
            "firstname": "Verena",
            "initials": "V",
            "lastname": "Steinle"
        },
        {
            "affiliation": "Department of Orthopedics and Trauma Surgery, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstr. 200a, 69118, Heidelberg, Germany.",
            "firstname": "Marco",
            "initials": "M",
            "lastname": "G\u00f6tze"
        },
        {
            "affiliation": "Department of Orthopedics and Trauma Surgery, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstr. 200a, 69118, Heidelberg, Germany.",
            "firstname": "S\u00e9bastien",
            "initials": "S",
            "lastname": "Hagmann"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2022. The Author(s).\n\u00a9 2022. The Author(s).",
    "doi": "10.1007/s00132-022-04278-x\n10.1016/s2213-8587(20)30307-7\n10.1186/1750-1172-4-5\n10.1155/2013/707343\n10.1016/j.bone.2013.04.007\n10.1016/j.amsu.2018.10.038\n10.1097/00003086-199309000-00005\n10.1038/s41413-019-0055-x\n10.1210/jc.2017-01127\n10.1111/j.1600-0714.1992.tb01032.x\n10.1046/j.1365-2990.2003.00474.x\n10.1007/s00198-011-1878-5\n10.1182/blood-2015-01-625541\n10.1002/jbmr.4037\n10.2147/IJGM.S289265\n10.17219/dmp/119998\n10.1007/s00264-018-4167-5\n10.1097/01.bot.0000145971.56642.12\n10.1016/j.jcot.2012.09.007\n10.1097/01241398-199901000-00026\n10.1007/s002560050430\n10.1007/s00402-002-0391-x\n10.2106/00004623-196749050-00001\n10.1097/00003086-199411000-00014\n10.1097/01241398-198507000-00020\n10.1155/2014/891963\n10.1007/s00402-007-0392-x\n10.1136/bcr-2020-236891\n10.1302/0301-620x.102b8.Bjj-2020-0431.R1\n10.1093/jhps/hnx032",
    "journal": "Orthopadie (Heidelberg, Germany)",
    "keywords": [
        "Congenital disease",
        "Femoral neck fracture",
        "Growth plate",
        "Osteosynthesis",
        "Osteotomy",
        "Pathologic fracture"
    ],
    "methods": null,
    "publication_date": "2022-07-09",
    "pubmed_id": "35802155\n32946815\n16385937\n19232111\n24260721\n23685543\n30505439\n8358940\n31231577\n28655174\n1432738\n12662317\n23399783\n22231430\n26012570\n32329913\n20141071\n33364816\n33113292\n30284606\n16056085\n26403447\n9890301\n9809882\n12070653\n6029256\n7955707\n4019766\n24579054\n17639433\n33318240\n32731834\n29250335",
    "results": null,
    "title": "Pediatric patient with a\u00a0bilateral Salter-Harris II fracture and slipped capital femoral epiphysis secondary to autosomal recessive osteopetrosis.",
    "xml": "<Element 'PubmedArticle' at 0x788503d84720>"
}