{
    "abstract": "This case report details a rare instance of total reversal of the pulmonary circulation (RPC) in a 56-year-old male patient on veno-arterial extracorporeal membrane oxygenation (V-A ECMO) during emergency cardiopulmonary resuscitation (eCPR) following a myocardial infarction and cardiac arrest. Previously unrecognized aortic and mitral valve regurgitations, along with V-A ECMO flow, resulted in severe pulmonary edema. We describe how pulmonary artery cannulation and modifying the ECMO circuit to veno-pulmonary arterial-arterial (VPa-A) ECMO successfully alleviated the severe pulmonary edema but may have caused reversal of the pulmonary circulation (RPC). To our knowledge, this is the first reported case of this phenomenon in a human.",
    "authors": [
        {
            "affiliation": "Internal Medicine Intensive Care, Klinikum Stuttgart, Kriegsbergstrasse 60, 70174, Stuttgart, Germany.",
            "firstname": "Johannes",
            "initials": "J",
            "lastname": "Heymer"
        },
        {
            "affiliation": "Internal Medicine Intensive Care, Klinikum Stuttgart, Kriegsbergstrasse 60, 70174, Stuttgart, Germany.",
            "firstname": "Daniel",
            "initials": "D",
            "lastname": "Bent"
        },
        {
            "affiliation": "Internal Medicine Intensive Care, Klinikum Stuttgart, Kriegsbergstrasse 60, 70174, Stuttgart, Germany. d.raepple@klinikum-stuttgart.de.",
            "firstname": "Daniel",
            "initials": "D",
            "lastname": "Raepple"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2024. The Author(s), under exclusive licence to the Japanese Society for Artificial Organs.",
    "doi": "10.1007/s10047-024-01483-7\n10.1097/MAT.0000000000000991\n10.1093/icvts/ivz245\n10.1177/0267659118794112\n10.1038/s41598-022-21501-z\n10.1016/S0022-5223(19)40344-9\n10.1016/S0022-5223(19)36836-9\n10.1016/s0003-4975(10)63727-7\n10.1152/jappl.1992.73.1.195",
    "journal": "Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs",
    "keywords": [
        "Aortic valve regurgitation",
        "Mitral valve regurgitation",
        "Pulmonary edema",
        "Reverse pulmonary blood flow",
        "V-A ECMO"
    ],
    "methods": null,
    "publication_date": "2024-12-13",
    "pubmed_id": "39668272\n30908287\n31665308\n30112975\n36224296\n239294\n2246914\n879897\n1506368",
    "results": null,
    "title": "Total reversal of the pulmonary circulation (RPC) induced by peripheral cannulation for veno-arterial ECMO in a patient with aortic and mitral valve insufficiency: a case report.",
    "xml": "<Element 'PubmedArticle' at 0x78850541e750>"
}