{
    "abstract": "BackgroundWe aimed to identify risk factors associated with chronic anastomotic leak (AL) treatment failure.MethodsAdult patients surgically treated for chronic AL after colorectal or coloanal anastomosis for benign and malignant indications were included. The primary outcome was predictors of AL treatment failure, defined as failure to restore bowel continuity and/or having a permanent stoma at completion of treatment. Step-wise multivariable logistic regression analysis of factors that reached statistical significance on univariable analyses was undertaken.Results60 patients [41 (68.3%) males; average age: 56 (SD 6.7) years; and average BMI: 24 (SD 2.1) kg/m",
    "authors": [
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.",
            "firstname": "Justin",
            "initials": "J",
            "lastname": "Dourado"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.\nColorectal Surgery Unit, General Surgery Department, Mansoura University Hospitals, Mansoura, Egypt.",
            "firstname": "Sameh Hany",
            "initials": "SH",
            "lastname": "Emile"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.",
            "firstname": "Anjelli",
            "initials": "A",
            "lastname": "Wignakumar"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.",
            "firstname": "Brett",
            "initials": "B",
            "lastname": "Weiss"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.\nDepartment of Surgery and Transplantations, Sheba Medical Center, Ramat Gan and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Nir",
            "initials": "N",
            "lastname": "Horesh"
        },
        {
            "affiliation": "American University of the Caribbean, Cupecoy, St. Maarte.",
            "firstname": "Victoria",
            "initials": "V",
            "lastname": "DeTrolio"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.\nDepartment of General Surgery, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.",
            "firstname": "Rachel",
            "initials": "R",
            "lastname": "Gefen"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.",
            "firstname": "Zoe",
            "initials": "Z",
            "lastname": "Garoufalia"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.",
            "firstname": "Peter",
            "initials": "P",
            "lastname": "Rogers"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.",
            "firstname": "Victor",
            "initials": "V",
            "lastname": "Strassmann"
        },
        {
            "affiliation": "Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, FL, USA.",
            "firstname": "Steven D",
            "initials": "SD",
            "lastname": "Wexner"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1177/00031348251337163",
    "journal": "The American surgeon",
    "keywords": [
        "anastomotic leak",
        "chronic",
        "coloanal",
        "colorectal",
        "permanent stoma",
        "treatment"
    ],
    "methods": null,
    "publication_date": "2025-04-24",
    "pubmed_id": "40272008",
    "results": null,
    "title": "Repeated Treatments for Chronic Colorectal and Coloanal Anastomotic Leaks are Associated With a Higher Chance of a Permanent Stoma.",
    "xml": "<Element 'PubmedArticle' at 0x788504ee0090>"
}