{
    "abstract": "To observe the effects of pre-electroacupuncture at \"Taichong\"(LR3), \"Neiguan\"(PC6) and \"Waiguan\"(TE5) on blood pressure and cardiac function of high-salt-induced hypertension rats, so as to explore the possible mechanism of pre-electroacupuncture in improving hypertension.\nTwenty-four SD rats were randomly divided into control group, high-salt group and pre-electroacupuncture group, with 8 rats in each group. The hypertension model was established by feeding high-salt diet for 7 weeks. In the pre-electroacupuncture group, rats received electroacupuncture intervention at bilate-ral LR3, PC6 and TE5 (2 Hz/15 Hz, 2 mA) for 30 min, once a day, from the first day of modeling, for a total of 7 weeks. The blood pressure of rats was monitored by caudal artery noninvasive blood pressure measurement technique before and at the 1\nCompared with the control group, systolic blood pressure, diastolic blood pressure, mean arterial pressure, left ventricular end-diastolic pressure (LVEDP), cardiac mass ratio\uff0cand the mRNA expressions of ANP, MYH7, \u03b1-SMA, IL-1\u03b2, and IL-6, and sirius red staining area of myocardium were all significantly increased(\nPre-electroacupuncture tends to lower blood pressure, improve cardiac function and reduce myocardial fibrosis in high-salt-induced hypertension rats, which may be associated with inhibiting inflammatory response.",
    "authors": [
        {
            "affiliation": "Department of Physiology School of Basic Medicine, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi Province, China.",
            "firstname": "Bing-Ying",
            "initials": "BY",
            "lastname": "Fang"
        },
        {
            "affiliation": "Shaanxi Key Laboratory of Integrated Traditional and Western Medicine for Prevention and Treatment of Cardiovascular Diseases, Xianyang 712046, Shaanxi Province.",
            "firstname": "Ting",
            "initials": "T",
            "lastname": "Du"
        },
        {
            "affiliation": "Shaanxi Key Laboratory of Integrated Traditional and Western Medicine for Prevention and Treatment of Cardiovascular Diseases, Xianyang 712046, Shaanxi Province.",
            "firstname": "Yuan-Wang",
            "initials": "YW",
            "lastname": "Yu"
        },
        {
            "affiliation": "Shaanxi Key Laboratory of Integrated Traditional and Western Medicine for Prevention and Treatment of Cardiovascular Diseases, Xianyang 712046, Shaanxi Province.",
            "firstname": "Hai-Fang",
            "initials": "HF",
            "lastname": "Wang"
        },
        {
            "affiliation": "Department of Physiology School of Basic Medicine, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi Province, China.",
            "firstname": "Xiao-Hua",
            "initials": "XH",
            "lastname": "Liu"
        }
    ],
    "conclusions": "Pre-electroacupuncture tends to lower blood pressure, improve cardiac function and reduce myocardial fibrosis in high-salt-induced hypertension rats, which may be associated with inhibiting inflammatory response.",
    "copyrights": null,
    "doi": "10.13702/j.1000-0607.20220731",
    "journal": "Zhen ci yan jiu = Acupuncture research",
    "keywords": [
        "Cardiac function",
        "Hypertension",
        "Inflammation",
        "Myocardial fibrosis",
        "Pre-electroacupuncture"
    ],
    "methods": null,
    "publication_date": "2023-07-31",
    "pubmed_id": "37518960",
    "results": "Compared with the control group, systolic blood pressure, diastolic blood pressure, mean arterial pressure, left ventricular end-diastolic pressure (LVEDP), cardiac mass ratio\uff0cand the mRNA expressions of ANP, MYH7, \u03b1-SMA, IL-1\u03b2, and IL-6, and sirius red staining area of myocardium were all significantly increased(",
    "title": "[Effects of pre-electroacupuncture on blood pressure and cardiac function in high-salt-induced hypertension rats].",
    "xml": "<Element 'PubmedArticle' at 0x7885041e0450>"
}