{
    "abstract": "The significance of cancer treatment research lies in addressing the high incidence of cancer, overcoming treatment challenges, and mitigating the harsh side effects of chemotherapeutic agents. Currently, nanotechnology is garnering significant attention for its potential applications in diagnostics and drug delivery, offering innovative solutions for disease detection and treatment. Among different types of nanoparticles (NPs), polymeric nanoparticles comprise\u00a0biocompatible and biodegradable polymers that\u00a0enhance drug pharmacokinetics and pharmacodynamics, minimize adverse effects, increase stability, and facilitate sustained drug release. These polymeric nanoparticle-based nanomedicines offer a versatile platform for various cancer treatments, notably enabling targeted drug delivery directly to tumors, tumor-imaging, hyperthermia, and photodynamic therapy. Being polymeric in nature polydopamine (PDA) nanomaterials are appeared as promising approaches in biology and medicine. This review article offers a concise summary of the latest developments in polydopamine-based cancer treatment, covering key findings, limitations, and emerging trend therapeutic approach of polydopamine nanomaterials, along with the properties and various methods of preparation. Physico-chemical properties of PDA-based nanomaterials in therapeutics have permitted several successful modifications in the field of cancer treatment.",
    "authors": [
        {
            "affiliation": "Department of Human Physiology, Biochemistry, Molecular Endocrinology and Reproductive Physiology Laboratory, Vidyasagar University, Midnapore, West Bengal, 721102, India.",
            "firstname": "Rumi",
            "initials": "R",
            "lastname": "Mahata"
        },
        {
            "affiliation": "Department of Human Physiology, Biochemistry, Molecular Endocrinology and Reproductive Physiology Laboratory, Vidyasagar University, Midnapore, West Bengal, 721102, India.",
            "firstname": "Sounik",
            "initials": "S",
            "lastname": "Manna"
        },
        {
            "affiliation": "Department of Human Physiology, Biochemistry, Molecular Endocrinology and Reproductive Physiology Laboratory, Vidyasagar University, Midnapore, West Bengal, 721102, India.",
            "firstname": "Mrinmoyee",
            "initials": "M",
            "lastname": "Modak"
        },
        {
            "affiliation": "Department of Human Physiology, Biochemistry, Molecular Endocrinology and Reproductive Physiology Laboratory, Vidyasagar University, Midnapore, West Bengal, 721102, India. sujata_vu@mail.vidyasagar.ac.in.",
            "firstname": "Sujata Maiti",
            "initials": "SM",
            "lastname": "Choudhury"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
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    "journal": "Medical oncology (Northwood, London, England)",
    "keywords": [
        "Cancer therapy",
        "Drug delivery system",
        "Photothermal activity",
        "Polydopamine",
        "Polymeric nanoparticles"
    ],
    "methods": null,
    "publication_date": "2025-04-16",
    "pubmed_id": "40237855\n35159802\n35478636\n36080203\n37446593\n37981671\n34522587\n25340503\n34094435\n36902321\n32272786\n27933877\n25317902\n37489635\n23797829\n29058908\n31105189\n28754539\n29745764\n29567310\n34552912\n32365146\n31408811\n33586444\n34522935\n29568455\n32262465\n29376345\n31581532\n26731575\n29871485\n29783745\n35558470\n26965036\n32021991\n32637781\n30606519\n30787876\n33855009\n31910019\n31193800\n32286806\n26602819\n26941841\n28414557\n26550786\n32762008\n27086698\n35921245\n12612576\n33405783\n35016291\n36744246\n34830777\n30852424\n31482919\n37214280\n30978027\n37180014\n16754338\n32555349\n30312718\n33387938\n34726401\n35014822\n35642529\n35403518\n32974312\n29457518\n37457660\n35559812",
    "results": null,
    "title": "A review on the advancement of polydopamine (PDA)-based nanomaterials for cancer treatment.",
    "xml": "<Element 'PubmedArticle' at 0x788504b2e2a0>"
}