{
    "abstract": "In 1979-1984, 135 women (age unspecified) received drug therapy for various inflammatory diseases following delivery, abortion or gynecological surgery. The group included 36 women who had total hysterectomy and bilateral adnexitis; 11 patients who had total hysterectomy, bilateral adnexitis and resection of the intestine; 24 who had either spontaneous abortion or abortion on demand; 5 who had an illegal abortion; 52 who had cesarean section; 14 who had the forceps delivery or episiotomy; and 4 who had normal delivery (numbers do not add up). Clinical manifestations of postoperative complications could be detected during the early postoperative period. Bacteriological examination of the specimens of wound secretions, cervical secretions and abdominal exudate showed the presence of Escherichia coli, Bacteroides, Streptococcus faecalis, and anaerobic cocci. Anaerobic bacteria accounted for more than 50% of severe inflammatory complications. Anaerobic bacteria played an especially important etiological role in the patients with sepsis after illegal abortion or cesarean section. The patients received antibiotics in accordance with the results of in vitro testing of microbial resistance. Preliminary results of testing were obtained within 48 hours, while the final results were obtained within 4-5 days. The doses and combinations of antibiotics were selected individually, according to the bacteriological diagnosis, severity of the disease, tolerance to antibiotics, and resistance of microorganisms. The most frequently used combination of antibiotics was penicillin (30-80 million units or 100-120 million units in the most severe cases, iv) together with gentamycin (3 x 80, iv) and colimycin (3.04.0). Other frequent combinations were amikacin (4 x 0.5, iv) and cephalosporin (4 x 0.5, iv); and vibramycin (im) or penicillin in combination with clindamycin and colimycin. In addition to antibiotics, the patients received vitamins and hyperbaric oxygenation. Clinical improvement was achieved within 7-14 days.",
    "authors": [
        {
            "affiliation": null,
            "firstname": "Kh",
            "initials": "Kh",
            "lastname": "Ivanova"
        },
        {
            "affiliation": null,
            "firstname": "K",
            "initials": "K",
            "lastname": "Mirkov"
        },
        {
            "affiliation": null,
            "firstname": "M",
            "initials": "M",
            "lastname": "Istatkov"
        },
        {
            "affiliation": null,
            "firstname": "S",
            "initials": "S",
            "lastname": "Krutilin"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": null,
    "journal": "Akusherstvo i ginekologiia",
    "keywords": [
        "Antibiotics--administraction and dosage",
        "Bacterial And Fungal Diseases",
        "Clinical Research",
        "Delivery--complications",
        "Diseases",
        "Drugs",
        "Economic Factors",
        "Infections",
        "Obstetrical Surgery",
        "Pregnancy",
        "Pregnancy Outcomes",
        "Reproduction",
        "Research And Development",
        "Research Methodology",
        "Surgery",
        "Technology",
        "Treatment"
    ],
    "methods": null,
    "publication_date": "1986-01-01",
    "pubmed_id": "3752396",
    "results": null,
    "title": "[Drug treatment of inflammatory postoperative complications].",
    "xml": "<Element 'PubmedArticle' at 0x7885039a2cf0>"
}