{
    "abstract": "Magnesium (Mg) alloys possess unique properties that make them ideal for use as biodegradable implants in clinical applications. However, reports on the in vivo assessment of these alloys are insufficient. Thus, monitoring the degradation of Mg and its alloys in vivo is challenging due to the dynamic process of implant degradation and tissue regeneration. Most current works focus on structural remodeling, but functional assessment is crucial in providing information about physiological changes in tissues, which can be used as an early indicator of healing. Here, we report continuous wave near-infrared spectroscopy (CW NIRS), a non-invasive technique that is potentially helpful in assessing the implant-tissue dynamic interface in a rodent model. The purpose of this study was to investigate the effects on hemoglobin changes and tissue oxygen saturation (StO",
    "authors": [
        {
            "affiliation": "Faculty of Technology, Art and Design, Department of Mechanical, Electronic and Chemical Engineering, Oslo Metropolitan University, 0130 Oslo, Norway.",
            "firstname": "Hafiz Wajahat",
            "initials": "HW",
            "lastname": "Hassan"
        },
        {
            "affiliation": "Institute of Clinical Physiology, National Research Council (IFC-CNR), 56124 Pisa, Italy.\nInstitute of Life Sciences, Sant'Anna School of Advanced Studies, 56127 Pisa, Italy.",
            "firstname": "Eduarda",
            "initials": "E",
            "lastname": "Mota-Silva"
        },
        {
            "affiliation": "FUJIFILM VisualSonics, 1114 AB Amsterdam, The Netherlands.\nFaculty of Engineering, Institute for Materials Science, Christian-Albrecht University of Kiel, D-24143 Kiel, Germany.",
            "firstname": "Valeria",
            "initials": "V",
            "lastname": "Grasso"
        },
        {
            "affiliation": "Institute of Clinical Physiology, National Research Council (IFC-CNR), 56124 Pisa, Italy.\nInstitute of Life Sciences, Sant'Anna School of Advanced Studies, 56127 Pisa, Italy.",
            "firstname": "Leon",
            "initials": "L",
            "lastname": "Riehakainen"
        },
        {
            "affiliation": "FUJIFILM VisualSonics, 1114 AB Amsterdam, The Netherlands.",
            "firstname": "Jithin",
            "initials": "J",
            "lastname": "Jose"
        },
        {
            "affiliation": "Institute of Clinical Physiology, National Research Council (IFC-CNR), 56124 Pisa, Italy.",
            "firstname": "Luca",
            "initials": "L",
            "lastname": "Menichetti"
        },
        {
            "affiliation": "Faculty of Technology, Art and Design, Department of Mechanical, Electronic and Chemical Engineering, Oslo Metropolitan University, 0130 Oslo, Norway.",
            "firstname": "Peyman",
            "initials": "P",
            "lastname": "Mirtaheri"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.3390/s23042297\n10.1016/j.jcms.2015.12.009\n10.1016/j.actbio.2015.07.029\n10.1016/j.actbio.2019.10.014\n10.5301/JABFM.5000150\n10.1016/j.actbio.2012.10.008\n10.1016/j.biomaterials.2004.09.049\n10.1016/j.actbio.2009.12.037\n10.3390/jfb8040044\n10.1016/j.actbio.2016.03.039\n10.1186/s12880-017-0187-7\n10.1186/s13018-020-01696-5\n10.1007/s10856-011-4536-8\n10.1366/000370207779947657\n10.1186/1476-5918-5-5\n10.1016/j.atherosclerosis.2016.06.030\n10.1016/j.medengphy.2021.05.016\n10.3390/ijms23116099\n10.1016/j.jneumeth.2015.10.011\n10.1139/h04-031\n10.1016/j.actbio.2022.05.041\n10.1016/j.neuroimage.2013.05.004\n10.1097/CCM.0b013e318280416e\n10.1186/cc8008\n10.1038/s41467-022-30594-z\n10.1002/jor.24035\n10.1177/0003702820987847\n10.1366/0003702854248944\n10.1109/TUFFC.2013.2646\n10.1007/0-387-29540-2_32\n10.1088/0031-9155/33/12/008\n10.1117/1.JBO.18.10.105004\n10.1117/1.NPh.6.3.035005\n10.1088/0967-3334/35/4/717\n10.1016/j.pacs.2022.100367\n10.1080/09500348914550381\n10.1109/TBME.2006.873541\n10.1007/978-1-4684-5643-1_12\n10.3389/frsip.2022.984901\n10.3389/fninf.2018.00037\n10.1364/BOE.9.000086\n10.1038/pr.2013.133\n10.3390/jcm10091842\n10.1080/14686996.2018.1451717\n10.2170/jjphysiol.T649\n10.1177/20417314211047100",
    "journal": "Sensors (Basel, Switzerland)",
    "keywords": [
        "Mg alloys",
        "biodegradable implants",
        "in vivo monitoring",
        "near-infrared spectroscopy (NIRS)",
        "oxygen saturation (SO2)",
        "photoacoustic imaging (PAI)",
        "principal component analysis (PCA)",
        "tissue oxygen saturation (StO2)"
    ],
    "methods": null,
    "publication_date": "2023-03-01",
    "pubmed_id": "36850894\n26805919\n26210283\n31610341\n23728545\n23069319\n15621246\n20035905\n28954399\n27045693\n28196474\n32408885\n22190200\n17331316\n16704736\n27415611\n34154775\n35682779\n26549641\n15328595\n27432657\n35644328\n23684868\n23685577\n19951382\n35637230\n29727022\n33393349\n23661123\n16927693\n3237772\n24121731\n31423455\n24622337\n35601933\n16761832\n2782194\n29973875\n29359089\n23942560\n33922759\n29707071\n16197604\n34589198",
    "results": null,
    "title": "Near-Infrared Spectroscopy for the In Vivo Monitoring of Biodegradable Implants in Rats.",
    "xml": "<Element 'PubmedArticle' at 0x7885038f0180>"
}