{
    "abstract": "Chromosomal structural variation leads to rice hybrid sterility, and this study has established a new inheritance model and offers a novel insight into hybrid sterility in rice. The utilization of heterosis among different species significantly enhances rice yield. However, the direct application of this advantage is hindered by hybrid sterility (HS). Here we identify a stable semi-sterile inbred line (SSIL) in the hybridization between rice species O. sativa indica and wild rice O. longistaminata. Both pollen and spikelet fertility in heterozygous SSIL plants are semi-sterile, and the homozygous plants show normal fertility. Interestingly, unlike previously reported hybrid sterility loci, SSIL does not induce segregation distortion in progeny. The genotypes of chromosome 1 (Chr.1) exhibit tight pseudo-linkage on Chr.6 in SSIL population. HSS1 and HSS6 are named as the two loci of Chr.1 and Chr.6. Cytological observations revealed abnormalities in male and female gametes during meiosis, ultimately resulting in semi-sterile pollen and spikelet. HSS1 was narrowed down to a 190.6-kb interval and HSS6 to a 1391.6-kb region using an SSIL population of 10,393 plants. Through high-throughput sequencing and observation of chromosomal behavior during meiosis, a reciprocal translocation between the short arm of Chr.1 and the end of Chr.6 in the translocated RD23-type (R",
    "authors": [
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Siqi",
            "initials": "S",
            "lastname": "Cheng"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Zhenwei",
            "initials": "Z",
            "lastname": "Xie"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Hao",
            "initials": "H",
            "lastname": "Yu"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Chaolong",
            "initials": "C",
            "lastname": "Wang"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Xiaowen",
            "initials": "X",
            "lastname": "Yu"
        },
        {
            "affiliation": "State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.",
            "firstname": "Jian",
            "initials": "J",
            "lastname": "Wang"
        },
        {
            "affiliation": "State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.",
            "firstname": "Hai",
            "initials": "H",
            "lastname": "Zheng"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Jiayu",
            "initials": "J",
            "lastname": "Lu"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Xiaodong",
            "initials": "X",
            "lastname": "He"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Keyi",
            "initials": "K",
            "lastname": "Chen"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Junwen",
            "initials": "J",
            "lastname": "Gao"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Yang",
            "initials": "Y",
            "lastname": "Hu"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Bowen",
            "initials": "B",
            "lastname": "Yao"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Dekun",
            "initials": "D",
            "lastname": "Lei"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Shimin",
            "initials": "S",
            "lastname": "You"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Qiming",
            "initials": "Q",
            "lastname": "Wang"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Anqi",
            "initials": "A",
            "lastname": "Jian"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Ling",
            "initials": "L",
            "lastname": "Jiang"
        },
        {
            "affiliation": "State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.",
            "firstname": "Yulong",
            "initials": "Y",
            "lastname": "Ren"
        },
        {
            "affiliation": "State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.",
            "firstname": "Xiuping",
            "initials": "X",
            "lastname": "Guo"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Yunlu",
            "initials": "Y",
            "lastname": "Tian"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Shijia",
            "initials": "S",
            "lastname": "Liu"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China.",
            "firstname": "Xi",
            "initials": "X",
            "lastname": "Liu"
        },
        {
            "affiliation": "State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China. zhushanshan@caas.cn.",
            "firstname": "Shanshan",
            "initials": "S",
            "lastname": "Zhu"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China. zhaozg@njau.edu.cn.",
            "firstname": "Zhigang",
            "initials": "Z",
            "lastname": "Zhao"
        },
        {
            "affiliation": "State Key Laboratory for Crop Genetics & Germplasm Enhancement and Utilization, Nanjing Agricultural University, Zhongshan Biological Breeding Laboratory, Nanjing, 210095, China. wanjianmin@caas.cn.\nState Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China. wanjianmin@caas.cn.",
            "firstname": "Jianmin",
            "initials": "J",
            "lastname": "Wan"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",
    "doi": "10.1007/s00122-025-04887-y\n10.1038/s41477-020-0663-x\n10.1093/bioinformatics/btu170\n10.1146/annurev-genom-082509-141554\n10.1016/j.molp.2020.06.009\n10.1038/ncomms15324\n10.1007/s00122-023-04348-4\n10.1146/annurev-genet-112618-043905\n10.1146/annurev-arplant-042817-040113\n10.1007/s00122-018-3233-0\n10.1111/nph.17907\n10.1146/annurev.ecolsys.39.110707.173532\n10.1104/pp.18.01374\n10.1270/jsbbs1951.12.81\n10.1101/gr.215087.116\n10.1270/jsbbs.63.359\n10.1016/j.molp.2015.09.014\n10.1534/genetics.105.042242\n10.1093/bioinformatics/btp324\n10.1038/s41467-024-45377-x\n10.1073/pnas.0810108105\n10.1038/s41586-018-0374-x\n10.1073/pnas.0510791103\n10.1101/gr.107524.110\n10.1146/annurev-arplant-050213-035923\n10.1073/pnas.1003124107\n10.1016/j.isci.2024.109761\n10.1534/g3.117.043943\n10.1016/j.jgg.2018.10.004\n10.1371/journal.pone.0162169\n10.1038/nrg2718\n10.1016/S0169-5347(01)02187-5\n10.1093/aob/mcq126\n10.1016/j.xplc.2020.100118\n10.1038/s41477-021-00910-4\n10.1093/jxb/eraa463\n10.1016/j.ceb.2013.02.015\n10.1126/science.1237150\n10.1093/nar/gkx739\n10.1038/s41467-020-18277-z\n10.1111/tpj.14322\n10.1007/s42994-019-00002-0\n10.1038/s41592-018-0001-7\n10.1038/s41586-018-0382-x\n10.1038/s41467-017-01400-y\n10.1111/evo.12503\n10.1111/tpj.12105\n10.1038/s41438-021-00687-9\n10.1101/gr.214270.116\n10.1016/j.jgg.2024.01.007\n10.1111/nph.17671\n10.1093/nar/gkr1293\n10.1038/nrg3373\n10.1038/s41467-019-10488-3\n10.1073/pnas.0908283107\n10.1126/science.1223702\n10.1038/s41467-023-43015-6\n10.1126/science.aar4279\n10.1534/genetics.115.183848\n10.1111/tpj.14537",
    "journal": "TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik",
    "keywords": [],
    "methods": null,
    "publication_date": "2025-04-15",
    "pubmed_id": "40232312\n32451449\n24695404\n20438362\n32585190\n28469237\n36971843\n31505133\n29505737\n30448864\n34873717\n20419035\n30770460\n28298431\n24399907\n26455463\n16183908\n19451168\n38307858\n19033192\n30069047\n16549785\n20644199\n25494464\n21048083\n38706863\n28592558\n30459118\n27622539\n20051985\n11403867\n20576737\n33367271\n33958776\n33258473\n23498663\n23929981\n28977556\n32887885\n30900787\n36305002\n29713083\n30069045\n29101356\n25125144\n23289725\n34848689\n28100585\n38325701\n34363228\n22217600\n23329113\n31175302\n20080642\n22984070\n37980335\n29880691\n27182946\n31529543",
    "results": null,
    "title": "Chromosomal structural variation loci HSS1 and HSS6 lead to hybrid sterility in rice.",
    "xml": "<Element 'PubmedArticle' at 0x7885050c2890>"
}