{
    "abstract": "Background Recently, diastolic stress testing and invasive hemodynamic measurements have been emphasized for diagnosis of heart failure with preserved ejection fraction (HFpEF) because when determined using noninvasive parameters it can fall into a nondiagnostic intermediate range. The current study evaluated the discriminative and prognostic roles of invasive measured left ventricular end-diastolic pressure in the population with suspected HFpEF, particularly for patients with intermediate Heart Failure Association Pre-test Assessment, Echocardiography & Natriuretic Peptide, Functional Testing, Final Etiology (HFA-PEFF) score. Methods and Results A total of 404 patients with symptoms or signs of HF and preserved left ventricular systolic function were enrolled. All subjects underwent left heart catheterization with left ventricular end-diastolic pressure measurement for confirmation of HFpEF (\u226516\u2009mm\u2009Hg). The primary outcome was all-cause death or readmission due to HF within 10\u2009years. Among the study population, 324 patients (80.2%) were diagnosed as invasively confirmed HFpEF, and 80 patients (19.8%) were as noncardiac dyspnea. The patients with HFpEF showed a significantly higher HFA-PEFF score than the patients with noncardiac dyspnea (3.8\u00b11.8 versus 2.6\u00b11.5, ",
    "authors": [
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Ki Hong",
            "initials": "KH",
            "lastname": "Choi"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.\nDepartment of Critical Care Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Jeong Hoon",
            "initials": "JH",
            "lastname": "Yang"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine Kangwon National University Hospital Chuncheon, Gangwon-Do Republic of Korea.",
            "firstname": "Jeong Hun",
            "initials": "JH",
            "lastname": "Seo"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "David",
            "initials": "D",
            "lastname": "Hong"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Taeho",
            "initials": "T",
            "lastname": "Youn"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Hyun Sung",
            "initials": "HS",
            "lastname": "Joh"
        },
        {
            "affiliation": "Department of Internal Medicine and Cardiovascular Center Chonnam National University Hospital Gwangju Republic of Korea.",
            "firstname": "Seung Hun",
            "initials": "SH",
            "lastname": "Lee"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Darae",
            "initials": "D",
            "lastname": "Kim"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Taek Kyu",
            "initials": "TK",
            "lastname": "Park"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Joo Myung",
            "initials": "JM",
            "lastname": "Lee"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Young Bin",
            "initials": "YB",
            "lastname": "Song"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Jin-Oh",
            "initials": "JO",
            "lastname": "Choi"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Joo-Yong",
            "initials": "JY",
            "lastname": "Hahn"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Seung-Hyuk",
            "initials": "SH",
            "lastname": "Choi"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Hyeon-Cheol",
            "initials": "HC",
            "lastname": "Gwon"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.",
            "firstname": "Eun-Seok",
            "initials": "ES",
            "lastname": "Jeon"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1161/JAHA.122.027581\n10.1056/NEJMcp1511175\n10.1056/NEJMoa1313731\n10.1093/eurheartj/ehx564\n10.1016/S0140-6736(03)14285-7\n10.1093/eurheartj/ehl250\n10.1056/NEJMoa0805450\n10.1056/NEJMoa1908655\n10.1093/eurheartj/ehz641\n10.1002/ejhf.1614\n10.1038/s41598-021-03974-6\n10.1016/j.jchf.2020.03.013\n10.1002/ehf2.13302\n10.3389/fcvm.2021.656536\n10.1002/ejhf.2142\n10.1016/j.ijcard.2021.08.001\n10.3904/kjim.2021.272\n10.1016/j.echo.2014.10.003\n10.1016/j.echo.2016.01.011\n10.1093/eurheartj/ehq426\n10.1002/ehf2.13288\n10.1016/j.cardfail.2021.02.005\n10.1161/CIRCULATIONAHA.118.034646\n10.1161/circulationaha.116.024822\n10.1093/eurheartj/ehy268\n10.1161/CIRCULATIONAHA.120.050757\n10.1016/j.jchf.2017.08.005\n10.1002/ejhf.2019\n10.15420/cfr.2016:17:2",
    "journal": "Journal of the American Heart Association",
    "keywords": [
        "HFA\u2010PEFF score",
        "heart failure with preserved ejection fraction",
        "left ventricular end\u2010diastolic pressure",
        "let heart catheterization",
        "prognosis"
    ],
    "methods": null,
    "publication_date": "2023-03-10",
    "pubmed_id": "36892042\n27959663\n24716680\n29040525\n13678871\n16963472\n19001508\n31475794\n31504452\n31472035\n34996984\n32535127\n33760383\n34778384\n33634544\n34364907\n34929994\n25559473\n27037982\n21138935\n33709628\n33647474\n29792299\n28039229\n29788047\n33464963\n29032138\n33012125\n28785461",
    "results": null,
    "title": "Discriminative Role of Invasive Left Heart Catheterization in Patients Suspected of Heart Failure With Preserved Ejection Fraction.",
    "xml": "<Element 'PubmedArticle' at 0x7885049a1d00>"
}