{
    "abstract": "The decision for resection of adrenal metastasis from colorectal cancers remain controversial and there is no proposed standard treatment. The aim of the article is to review the available literature on outcomes and complications rates following adrenalectomy for adrenal metastasis from colorectal cancer.\nRelevant papers were identified through electronic databases. Data was extracted independently by two authors on a Microsoft Excel spreadsheet up to June 2023.\nA total of 55 studies were included in the final analysis (145 cases). A large proportion of patients had an uneventful postoperative recovery following surgical adrenalectomy. The mean length of follow up ranged from 2\u2009months to 9.5\u2009years. A total of 33 (22.8%) patients were alive and well with no evidence of local or systemic recurrence; 2 (1.4%) patients had recurrence in the bed of adrenalectomy; 2 (1.4%) patients were alive with recurrence in the contralateral adrenal gland; 4 (2.8%) patients were alive with extra-adrenal metastasis, and 7 (4.8%) patients were alive and well with no comments regarding local and systemic recurrence. Post-operative mortality following adrenalectomy was uncommon: 1 patient died due to systemic sepsis following anastomotic leak. 17.2% of patients died due to disease progression.\nIf complete resection can be achieved, surgical adrenalectomy in the surgically fit patient should be strongly considered, especially in patients with solitary adrenal metastasis which may translate into survival benefits and potential surgical cure.",
    "authors": [
        {
            "affiliation": "Department of Colon & Rectal Surgery, Liverpool Hospital, Sydney, New South Wales, Australia.",
            "firstname": "Thi Ai Van Terresa",
            "initials": "TAVT",
            "lastname": "Nguyen"
        },
        {
            "affiliation": "Department of General Surgery, Royal Perth Hospital, Perth, Western Australia, Australia.",
            "firstname": "Sze Ling",
            "initials": "SL",
            "lastname": "Wong"
        },
        {
            "affiliation": "Department of Colon & Rectal Surgery, Liverpool Hospital, Sydney, New South Wales, Australia.\nDepartment of General Surgery, Royal Perth Hospital, Perth, Western Australia, Australia.\nSchool of Medicine, University of New South Wales, Sydney, New South Wales, Australia.",
            "firstname": "Zi Qin",
            "initials": "ZQ",
            "lastname": "Ng"
        }
    ],
    "conclusions": "If complete resection can be achieved, surgical adrenalectomy in the surgically fit patient should be strongly considered, especially in patients with solitary adrenal metastasis which may translate into survival benefits and potential surgical cure.",
    "copyrights": "\u00a9 2024 The Authors. ANZ Journal of Surgery published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Surgeons.",
    "doi": "10.1111/ans.18923",
    "journal": "ANZ journal of surgery",
    "keywords": [
        "adrenal",
        "cancer",
        "colorectal",
        "metastasis",
        "resection"
    ],
    "methods": null,
    "publication_date": "2024-03-01",
    "pubmed_id": "38426378",
    "results": "A total of 55 studies were included in the final analysis (145 cases). A large proportion of patients had an uneventful postoperative recovery following surgical adrenalectomy. The mean length of follow up ranged from 2\u2009months to 9.5\u2009years. A total of 33 (22.8%) patients were alive and well with no evidence of local or systemic recurrence; 2 (1.4%) patients had recurrence in the bed of adrenalectomy; 2 (1.4%) patients were alive with recurrence in the contralateral adrenal gland; 4 (2.8%) patients were alive with extra-adrenal metastasis, and 7 (4.8%) patients were alive and well with no comments regarding local and systemic recurrence. Post-operative mortality following adrenalectomy was uncommon: 1 patient died due to systemic sepsis following anastomotic leak. 17.2% of patients died due to disease progression.",
    "title": "Surgical resection of adrenal metastasis from colorectal cancers: a systematic review.",
    "xml": "<Element 'PubmedArticle' at 0x788503bd6c50>"
}