{
    "abstract": "To assess the accuracy of ultrasound measurement of the lower uterine segment (LUS) thickness against findings at laparotomy, and to investigate its correlation with the success rate of vaginal birth after one previous caesarean delivery (CD) in a resource-limited setting.\nProspective study.\nObstetrics and Gynaecology department in a tertiary hospital in Ghana.\nWomen with one previous CD undergoing either a trial of labour (TOLAC) or elective CD.\nMyometrial lower uterine segment thickness (mLUS) and full lower uterine segment thickness (fLUS) were measured with transvaginal ultrasound (TVUS). The women were managed according to local protocols with the clinicians blinded to the ultrasound measurements. The LUS was measured intraoperatively for comparison with ultrasound measurements.\nLower uterine segment findings at laparotomy, successful vaginal birth.\nA total of 311 pregnant women with one previous CD were enrolled; 147 women underwent elective CD and 164 women underwent a TOLAC. Of the women that underwent TOLAC, 96 (58.5%) women had a successful vaginal birth. The mLUS was comparable to the intraoperative measurement in the elective CD group with LUS thickness <5\u2009mm (bias of 0.01, 95% CI -0.10 to 0.12\u2009mm) whereas fLUS overestimated LUS <5\u2009mm (bias of 0.93, 95% CI 0.80-1.06\u2009mm). Successful vaginal birth rate correlated with increasing mLUS values (odds ratio 1.30, 95% CI 1.03-1.64). Twelve cases of uterine defect were recorded. LUS measurement \u22642.0\u2009mm was associated with an increased risk of uterine defects with a sensitivity of 91.7% (95% CI 61.5-99.8%) and specificity of 81.8% (95% CI 75.8-86.8%).\nAccurate TVUS measurement of the LUS is technically feasible in a resource-limited setting. This approach could help in making safer decisions on mode of birth in limited-resource settings.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynaecology Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.",
            "firstname": "Charles",
            "initials": "C",
            "lastname": "Adu-Takyi"
        },
        {
            "affiliation": "Women's Centre, John Radcliffe Hospital, Oxford, UK.",
            "firstname": "Rafique",
            "initials": "R",
            "lastname": "Munazzah"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.",
            "firstname": "Yaw Gyanteh",
            "initials": "YG",
            "lastname": "Owusu"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.",
            "firstname": "Atta",
            "initials": "A",
            "lastname": "Owusu-Bempah"
        },
        {
            "affiliation": "Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.",
            "firstname": "Bernard",
            "initials": "B",
            "lastname": "Arhin"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.\nObstetrics and Gynaecology Department, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.",
            "firstname": "Henry Sakyi",
            "initials": "HS",
            "lastname": "Opare-Addo"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.\nObstetrics and Gynaecology Department, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.",
            "firstname": "Amponsah",
            "initials": "A",
            "lastname": "Peprah"
        },
        {
            "affiliation": "Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.",
            "firstname": "Sally L",
            "initials": "SL",
            "lastname": "Collins"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.\nNuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.",
            "firstname": "Theophilus",
            "initials": "T",
            "lastname": "Adu-Bredu"
        }
    ],
    "conclusions": "Accurate TVUS measurement of the LUS is technically feasible in a resource-limited setting. This approach could help in making safer decisions on mode of birth in limited-resource settings.",
    "copyrights": "\u00a9 2024 The Author(s). BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd.",
    "doi": "10.1111/1471-0528.17872",
    "journal": "BJOG : an international journal of obstetrics and gynaecology",
    "keywords": [
        "caesarean delivery",
        "limited\u2010resource setting",
        "lower uterine segment",
        "trial of labour",
        "ultrasound measurement",
        "uterine rupture",
        "vaginal birth after caesarean"
    ],
    "methods": null,
    "publication_date": "2024-06-03",
    "pubmed_id": "38828568",
    "results": "A total of 311 pregnant women with one previous CD were enrolled; 147 women underwent elective CD and 164 women underwent a TOLAC. Of the women that underwent TOLAC, 96 (58.5%) women had a successful vaginal birth. The mLUS was comparable to the intraoperative measurement in the elective CD group with LUS thickness <5\u2009mm (bias of 0.01, 95% CI -0.10 to 0.12\u2009mm) whereas fLUS overestimated LUS <5\u2009mm (bias of 0.93, 95% CI 0.80-1.06\u2009mm). Successful vaginal birth rate correlated with increasing mLUS values (odds ratio 1.30, 95% CI 1.03-1.64). Twelve cases of uterine defect were recorded. LUS measurement \u22642.0\u2009mm was associated with an increased risk of uterine defects with a sensitivity of 91.7% (95% CI 61.5-99.8%) and specificity of 81.8% (95% CI 75.8-86.8%).",
    "title": "Accuracy of sonographic lower segment thickness and prediction of vaginal birth after caesarean in a resourced-limited setting; Prospective study.",
    "xml": "<Element 'PubmedArticle' at 0x788503960db0>"
}