{
    "abstract": "ObjectiveThe risk factors associated with hematoma formation following ultrasound (US)-guided vacuum-assisted excision (US-VAE) of breast fibroadenoma (FA), particularly those related to the US features of the lesions, remain unclear. This study aimed to investigate the US features influencing hematoma formation after US-VAE of FAs.Materials and methodsThis retrospective analysis included 137 patients with 145 FA nodules who underwent US-VAE at our hospital from January 2018 to August 2024, and subsequently underwent US follow-up to monitor hematoma formation and absorption. The US features of the lesions, including size, number of nodules removed, location, depth, distance from the nipple, peripheral tissue structure, and color Doppler flow features, were retrospectively analyzed to identify the potential risk factors associated with hematoma formation.ResultsHematomas formed in 78 nodules (53.8%) 24-48 h after the US-VAE procedure and disappeared within 6 months in 77 cases (98.7%). In the multivariate logistic regression analysis, FA depth\u2009\u2265\u20091.5 cm or <0.7 cm (OR = 2.490, 95% CI: 1.056-5.872; ",
    "authors": [
        {
            "affiliation": "Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.",
            "firstname": "Yunyun",
            "initials": "Y",
            "lastname": "Dong"
        },
        {
            "affiliation": "Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.",
            "firstname": "Yuqing",
            "initials": "Y",
            "lastname": "Huang"
        },
        {
            "affiliation": "Department of Clinical Epidemiology & EBM Unit, Beijing Friendship Hospital, Capital Medical University; National Clinical Research center for Digestive Diseases, Beijing, China.",
            "firstname": "Xinyu",
            "initials": "X",
            "lastname": "Zhao"
        },
        {
            "affiliation": "Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.",
            "firstname": "Lanyan",
            "initials": "L",
            "lastname": "Qiu"
        },
        {
            "affiliation": "Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.",
            "firstname": "Yu",
            "initials": "Y",
            "lastname": "Yang"
        },
        {
            "affiliation": "Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.",
            "firstname": "Xian-Quan",
            "initials": "XQ",
            "lastname": "Shi"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1177/00368504251338660",
    "journal": "Science progress",
    "keywords": [
        "Breast",
        "fibroadenoma",
        "hematoma",
        "vacuum-assisted breast biopsy",
        "vacuum-assisted excision"
    ],
    "methods": null,
    "publication_date": "2025-04-25",
    "pubmed_id": "40275675",
    "results": null,
    "title": "Risk factors for hematoma formation after ultrasound-guided vacuum-assisted excision of breast fibroadenoma: An analysis based on ultrasound features.",
    "xml": "<Element 'PubmedArticle' at 0x788504ebef70>"
}