{
    "abstract": "BACKGROUND This subgroup analysis of prospective observational research, involving 71 participants, compared the effects of anesthesia on microvascular reactivity in obese vs lean individuals using near-infrared spectroscopy and vascular occlusion tests. The correlation between the body mass index (BMI) and microvascular reactivity under general anesthesia was also investigated. MATERIAL AND METHODS This study enrolled adult patients classified as American Society of Anesthesiologists physical status I or II, undergoing elective surgery under general anesthesia. The microcirculatory variables measured before (Tpre) and 30 min following the induction of anesthesia (Tpost) were as follows: baseline tissue oxygen saturation (StO\u2082), occlusion slope (\u2207occl), and recovery slope (\u2207recov). The patients were grouped according to their BMI (lean [BMI <25 kg/m\u00b2] vs obese [BMI \u226525 kg/m\u00b2]). Data are presented as medians and interquartile ranges. RESULTS There were 43 patients in the lean group and 28 in the obese group. At Tpre, baseline StO2, \u2207occl, and \u2207recov were not different between the 2 groups (P=0.860, 0.659, and 0.518, respectively). At Tpost, the baseline StO\u2082 and \u2207occl were not different between the 2 groups (P=0.343 and 0.791); however, the \u2207recov was lower in the obese group than in the lean group (3.245 [2.737, 3.977] vs 4.131 [3.491, 4.843], P=0.003). At Tpost, BMI showed a moderate correlation with \u2207recov (correlation coefficient: -0.319, P=0.007). CONCLUSIONS In obese patients, capillary recruitment capacity during general anesthesia is compromised compared to lean patients.",
    "authors": [
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, School of Dentistry, Institute for Translational Research in Dentistry, Kyungpook National University, Daegu, South Korea.",
            "firstname": "Soeun",
            "initials": "S",
            "lastname": "Jeon"
        },
        {
            "affiliation": "Anesthesiology And Pain Medicine, Pusan National University Hospital, Busan, South Korea.\nDepartment of Anesthesia and Pain Medicine, Pusan National University, School of Medicine, Yangsan, Gyeongsangnam-do, South Korea.",
            "firstname": "Hyeon-Jeong",
            "initials": "HJ",
            "lastname": "Lee"
        },
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, Kyungpook National University, School of Medicine, Daegu, South Korea.",
            "firstname": "Hyun-Su",
            "initials": "HS",
            "lastname": "Ri"
        },
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, Pusan National University Hospital, Busan, South Korea.\nDepartment of Anesthesia and Pain Medicine, Pusan National University, School of Medicine, Yangsan, Gyeongsangnam-do, South Korea.",
            "firstname": "Ah-Reum",
            "initials": "AR",
            "lastname": "Cho"
        },
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, Pusan National University Hospital, Busan, South Korea.\nDepartment of Anesthesia and Pain Medicine, Pusan National University, School of Medicine, Yangsan, Gyeongsangnam-do, South Korea.",
            "firstname": "Hyae-Jin",
            "initials": "HJ",
            "lastname": "Kim"
        },
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, Pusan National University Hospital, Busan, South Korea.\nDepartment of Anesthesia and Pain Medicine, Pusan National University, School of Medicine, Yangsan, Gyeongsangnam-do, South Korea.",
            "firstname": "Jeong-Min",
            "initials": "JM",
            "lastname": "Hong"
        },
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, Pusan National University Hospital, Busan, South Korea.\nDepartment of Anesthesia and Pain Medicine, Pusan National University, School of Medicine, Yangsan, Gyeongsangnam-do, South Korea.",
            "firstname": "Jiseok",
            "initials": "J",
            "lastname": "Baik"
        },
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, Pusan National University Hospital, Busan, South Korea.",
            "firstname": "Eun Ji",
            "initials": "EJ",
            "lastname": "Park"
        },
        {
            "affiliation": "Department of Anesthesia and Pain Medicine, Pusan National University Hospital, Busan, South Korea.",
            "firstname": "Ohyun",
            "initials": "O",
            "lastname": "Kim"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu, South Korea.",
            "firstname": "Jae-Han",
            "initials": "JH",
            "lastname": "Kim"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.12659/MSM.943036",
    "journal": "Medical science monitor : international medical journal of experimental and clinical research",
    "keywords": [],
    "methods": null,
    "publication_date": "2024-02-03",
    "pubmed_id": "38308426\n35382771\n18066432\n35139609\n27147496\n33526968\n23684868\n17572876\n27442052\n36053289\n29140967\n26337035\n32488972\n28860741\n18818155\n34943456\n30454600\n28931323\n33150675\n15947345\n23720331\n16957821\n29681567\n21797844\n15298982\n28212203\n36759688\n35768944",
    "results": null,
    "title": "Impaired Capillary Recruitment Capacity in Obesity: A Subgroup Analysis of Prospective Observational Study on Anesthesia Effects.",
    "xml": "<Element 'PubmedArticle' at 0x788503384540>"
}