{
    "abstract": "We aim to review the most relevant diagnostic features and treatment options of retroperitoneal fibrosis, in order to provide a useful guide for clinical practice.\nThe recent literature highlights the role of imaging studies such as computed tomography, magnetic resonance imaging and positron emission tomography as useful tools for the diagnosis of retroperitoneal fibrosis, with retroperitoneal biopsy being reserved to atypical cases. The treatment approach is mainly conservative and is based on the use of medical therapies plus urological interventions. Medical therapies essentially comprise glucocorticoids and immunosuppressants-either traditional or biological agents such as rituximab. Surgical ureterolysis is only left for refractory cases. Recent findings in retroperitoneal fibrosis highlight the possibility of a non-invasive diagnostic approach and a conservative treatment strategy.",
    "authors": [
        {
            "affiliation": "Nephrology Unit, University Hospital, Parma, Italy.\nRenal Pathology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.",
            "firstname": "Paride",
            "initials": "P",
            "lastname": "Fenaroli"
        },
        {
            "affiliation": "Nephrology, Dialysis and Kidney Transplant Unit, Ospedali Riuniti, Ancona, Italy.",
            "firstname": "Federica",
            "initials": "F",
            "lastname": "Maritati"
        },
        {
            "affiliation": "Department of Biomedical, Experimental and Clinical Sciences \"Mario Serio\", University of Firenze, Florence, Italy. augusto.vaglio@unifi.it.\nDipartimento di Scienze Biomediche Sperimentali e Cliniche \"Mario Serio\", Universit\u00e0 di Firenze, Viale Pieraccini, 6, 50139, Florence, Italy. augusto.vaglio@unifi.it.\nNephrology and Dialysis Unit, Meyer Children's Hospital, Florence, Italy. augusto.vaglio@unifi.it.",
            "firstname": "Augusto",
            "initials": "A",
            "lastname": "Vaglio"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1007/s11926-020-00966-9\n10.1038/sj.ki.5002427\n10.1097/BOR.0b013e328341137d\n10.1097/MD.0b013e318207231e",
    "journal": "Current rheumatology reports",
    "keywords": [
        "Autoimmunity",
        "Glucocorticoids",
        "IgG4",
        "PET",
        "Retroperitoneal fibrosis",
        "Rituximab"
    ],
    "methods": null,
    "publication_date": "2021-02-12",
    "pubmed_id": "33569638\n17622270\n19508942\n21124080\n7962625\n17518371\n23740665\n19950407\n26860343\n21454732\n19476982\n22273666\n27876167\n31230189\n16920572\n25172237\n18647912\n23842972\n21418782\n18592800\n25455951\n22121132\n25036229\n28105551\n29105322\n8898793\n24702726\n20493425\n22801728\n28958769\n15895895\n30711361\n23497982\n24033464\n18353394\n17472843\n12365466\n12131307\n3985741\n7817165\n11247880\n16465670\n17499287\n7586991\n24854377\n16702201",
    "results": null,
    "title": "Into Clinical Practice: Diagnosis and Therapy of Retroperitoneal Fibrosis.",
    "xml": "<Element 'PubmedArticle' at 0x78850538ea20>"
}