{
    "abstract": "Left ventricular assist device (LVAD) therapy is well-established in the treatment of end-stage cardiac failure. Indications are bridge to transplant (BTT), bridge to candidacy (BTC), bridge to recovery (BTR), and destination therapy (DT). The durability and adverse event (AE) rate of LVADs have improved over the years. However, due to donor shortage, the duration of support in the BTT population has increased tremendously; similarly, DT patients are on the device for a long time. Consequently, the number of readmissions of long-term LVAD patients has increased. In cases of severe AEs, intensive care unit (ICU) treatment can be necessary. Infectious complications are the most common AE. Furthermore, embolic or hemorrhagic strokes can occur due to foreign surfaces, acquired von Willebrand syndrome, and anticoagulation treatment. Another consequence of the coagulative status, in combination with the continuous flow, are gastrointestinal bleeding events. Moreover, in most patients, an isolated LVAD is implanted, and this involves the risk of late right heart failure. Adjustment of pump speed and optimization of the volume status can help solve this issue. Malignant arrhythmias, pre-existing or ",
    "authors": [
        {
            "affiliation": "Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen 32545, Germany.",
            "firstname": "Michiel",
            "initials": "M",
            "lastname": "Morshuis"
        },
        {
            "affiliation": "Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen 32545, Germany.",
            "firstname": "Hendrik",
            "initials": "H",
            "lastname": "Fox"
        },
        {
            "affiliation": "Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen 32545, Germany.",
            "firstname": "Volker",
            "initials": "V",
            "lastname": "Lauenroth"
        },
        {
            "affiliation": "Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen 32545, Germany.",
            "firstname": "Rene",
            "initials": "R",
            "lastname": "Schramm"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2022 The Author(s).",
    "doi": "10.1016/j.jointm.2022.10.004\n10.1159/000491872\n10.1093/ejcts/ezz098\n10.1007/BF03085953\n10.1002/ejhf.2211\n10.1016/j.jtcvs.2022.03.035\n10.1093/icvts/ivy228\n10.1016/j.athoracsur.2020.12.038\n10.1016/j.healun.2017.06.007\n10.1016/j.jcrc.2019.12.014\n10.1093/ejcts/ezx016\n10.1089/wound.2018.0832\n10.1097/MAT.0000000000001287\n10.1093/ejcts/ezab144\n10.1177/1076029615595881\n10.1056/NEJMe1413346\n10.1007/s11239-018-1680-8\n10.1097/MAT.0000000000000783\n10.1111/jth.13933\n10.1097/CRD.0000000000000212\n10.3748/wjg.v26.i20.2550\n10.14423/SMJ.0000000000000883\n10.3390/jcm11030613\n10.1016/j.jtcvs.2013.01.044\n10.1016/j.healun.2020.03.010\n10.1016/j.ccl.2020.01.005\n10.1111/aor.12518\n10.21037/jtd-20-2228\n10.1016/j.jacep.2018.05.006\n10.1111/aor.13638\n10.1111/aor.12570\n10.1016/j.jchf.2015.06.015\n10.1097/MAT.0000000000001483\n10.3390/ph14080739\n10.1016/j.healun.2013.12.001\n10.5301/ijao.5000626\n10.1016/j.jacc.2016.03.573\n10.1007/s10047-020-01228-2\n10.1016/j.athoracsur.2021.12.014\n10.1093/icvts/ivac149\n10.1016/j.jacc.2015.07.075\n10.1016/j.acvd.2012.09.006\n10.1016/j.jchf.2021.05.021",
    "journal": "Journal of intensive medicine",
    "keywords": [
        "Adverse events",
        "Heart failure",
        "Left ventricular assist device (LVAD) therapy"
    ],
    "methods": null,
    "publication_date": "2023-05-16",
    "pubmed_id": "37188121\n30048974\n31100109\n17612659\n33932272\n35624053\n30113626\n33465365\n28781010\n31896443\n28329162\n31737410\n33074867\n33871594\n26177662\n25517349\n29785470\n29561270\n29274191\n30520778\n32523310\n30392001\n35160064\n23434450\n32386998\n32284099\n26043796\n33717597\n30236390\n31945201\n26234450\n26454842\n34860184\n34451836\n24418731\n28777390\n27282897\n33337536\n34998738\n35642889\n26483097\n23374971\n34391745",
    "results": null,
    "title": "Long-term assist device patients admitted to ICU: Tips and pitfalls.",
    "xml": "<Element 'PubmedArticle' at 0x788505c092b0>"
}