{
    "abstract": "The mechanisms of action of elapid neurotoxins have been widely studied; however, the pathophysiological effects of these venoms, particularly from coral snakes, have not been extensively investigated. To gain a deeper understanding of the mechanisms involved in the local and systemic toxicity of Micrurus corallinus venom and their genomic responses, we injected mice with 2.70\u00a0\u03bcg of venom, corresponding to a sub-lethal dose (50\u00a0% of the LD",
    "authors": [
        {
            "affiliation": "Laborat\u00f3rio de Toxinologia Aplicada, CeTICs, Butantan Institute, S\u00e3o Paulo, Brazil.",
            "firstname": "Maria Andrea",
            "initials": "MA",
            "lastname": "Camarano Eula"
        },
        {
            "affiliation": "Laborat\u00f3rio de Toxinologia Aplicada, CeTICs, Butantan Institute, S\u00e3o Paulo, Brazil.",
            "firstname": "Juan David",
            "initials": "JD",
            "lastname": "Bayona-Serrano"
        },
        {
            "affiliation": "Laborat\u00f3rio de Toxinologia Aplicada, CeTICs, Butantan Institute, S\u00e3o Paulo, Brazil.",
            "firstname": "Milton Yutaka",
            "initials": "MY",
            "lastname": "Nishiyama-Jr"
        },
        {
            "affiliation": "Laborat\u00f3rio de Imunoqu\u00edmica, Butantan Institute, S\u00e3o Paulo, Brazil.",
            "firstname": "Carla Cristina",
            "initials": "CC",
            "lastname": "Squaiella-Baptist\u00e3o"
        },
        {
            "affiliation": "Biot\u00e9rio Central, Butantan Institute, S\u00e3o Paulo, Brazil.",
            "firstname": "Marcelo Larami",
            "initials": "ML",
            "lastname": "Santoro"
        },
        {
            "affiliation": "Laborat\u00f3rio de Toxinologia Aplicada, CeTICs, Butantan Institute, S\u00e3o Paulo, Brazil. Electronic address: inacio.azevedo@butantan.gov.br.",
            "firstname": "In\u00e1cio de Loiola Meirelles",
            "initials": "ILM",
            "lastname": "Junqueira-de-Azevedo"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2025 Elsevier Ltd. All rights reserved.",
    "doi": "10.1016/j.toxicon.2025.108368",
    "journal": "Toxicon : official journal of the International Society on Toxinology",
    "keywords": [
        "Envenomation",
        "Functional analysis",
        "Gene expression",
        "Histopathology",
        "Micrurus corallinus",
        "RNA-Seq"
    ],
    "methods": null,
    "publication_date": "2025-04-24",
    "pubmed_id": "40268250",
    "results": null,
    "title": "The underestimated local effects of Micrurus corallinus venom revealed by gene expression and histopathological alterations.",
    "xml": "<Element 'PubmedArticle' at 0x788500c329d0>"
}