{
    "abstract": "Immunoinflammatory responses and macrophage polarisation are crucial for maintaining ovarian function. Moreover, electroacupuncture (EA) has been shown to protect ovarian function. However, the mechanisms by which EA improves ovarian function, including its effects on immunoinflammatory responses and macrophage polarisation, have not been determined. This study aimed to investigate the protective effects of EA on ovarian function in rats with diminished ovarian reserve (DOR) and to elucidate the regulatory mechanisms underlying inflammation and M1 and M2 macrophage polarisation. DOR models were established through the intragastric administration of 50\u2009mg/kg ",
    "authors": [
        {
            "affiliation": "School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing 210023, China.",
            "firstname": "Jia",
            "initials": "J",
            "lastname": "Luo"
        },
        {
            "affiliation": "Department of Rehabilitation, Gaoyou Hospital of Traditional Chinese Medicine, Yangzhou 225600, China.",
            "firstname": "Yantong",
            "initials": "Y",
            "lastname": "Qin"
        },
        {
            "affiliation": "Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.",
            "firstname": "Yaoyao",
            "initials": "Y",
            "lastname": "Zhu"
        },
        {
            "affiliation": "School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing 210023, China.",
            "firstname": "Yaoli",
            "initials": "Y",
            "lastname": "Yin"
        },
        {
            "affiliation": "School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing 210023, China.\nKey Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China.",
            "firstname": "Meihong",
            "initials": "M",
            "lastname": "Shen"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2025 Jia Luo et al. Mediators of Inflammation published by John Wiley & Sons Ltd.",
    "doi": "10.1155/mi/1694470\n10.1186/s13048-023-01296-x\n10.1007/s43032-023-01252-6\n10.1080/01443615.2022.2109953\n10.1186/s13020-017-0131-3\n10.1155/2021/8817858\n10.1038/s41598-020-79488-4\n10.1073/pnas.1323955111\n10.1016/j.immuni.2016.02.015\n10.1002/jcp.26429\n10.1097/MOL.0b013e32834a77b4\n10.3390/ijms18071545\n10.1002/ctm2.1071\n10.1530/REP-19-0330\n10.3389/fendo.2023.1136121\n10.1631/jzus.B1600437\n10.1016/j.biopha.2021.111655\n10.13702/j.1000-0607.20211226\n10.13702/j.1000-0607.180576\n10.1590/S1519-69842002000400008\n10.1530/REP-16-0117\n10.1007/s10142-024-01284-4\n10.1371/journal.pone.0156130\n10.1126/sciadv.abc7409\n10.1093/humupd/dmh011\n10.3389/fgene.2020.590660\n10.1093/abbs/gmz065\n10.7150/ijms.61975\n10.1126/sciimmunol.aau6085\n10.1097/SHK.0000000000001601\n10.1016/j.immuni.2010.05.007\n10.1016/j.immuni.2014.06.008\n10.3389/fphar.2021.646240\n10.4292/wjgpt.v1.i5.107\n10.1016/j.ejphar.2020.173090\n10.1016/j.ajpath.2015.06.001\n10.1016/j.biomaterials.2014.06.060\n10.1007/s00418-020-01897-3\n10.13702/j.1000-0607.20220335\n10.13703/j.0255-2930.20190925-0003\n10.1016/j.brainres.2023.148233\n10.1038/nm.3479\n10.1016/j.neuron.2020.07.015\n10.1155/2024/8237681",
    "journal": "Mediators of inflammation",
    "keywords": [],
    "methods": null,
    "publication_date": "2025-04-09",
    "pubmed_id": "40201729\n26946729\n37880734\n37145300\n35959847\n28439292\n34135985\n33432051\n25114230\n26982353\n29319160\n24686541\n21825981\n28714933\n36229897\n31940276\n37600702\n27509613\n28271655\n36036103\n35616411\n34029955\n37186203\n31777230\n12659010\n27799628\n38189995\n27272680\n33523841\n15073142\n33304387\n31287492\n34522181\n38036420\n30824527\n32590701\n20510870\n25035950\n21462164\n34177571\n21577304\n32234529\n26118749\n25043569\n32617655\n37186205\n32959591\n36623758\n24562381\n32791039\n38974599",
    "results": null,
    "title": "Electroacupuncture Improves Ovarian Function in Rats With ",
    "xml": "<Element 'PubmedArticle' at 0x7885057de8e0>"
}