{
    "abstract": "",
    "authors": [
        {
            "affiliation": "Clinic'n'Cell SAS, Facult\u00e9 de M\u00e9decine, 28 Place Henri Dunant, 63001 Clermont-Ferrand, France.",
            "firstname": "Fabien",
            "initials": "F",
            "lastname": "Wauquier"
        },
        {
            "affiliation": "Valbiotis, 20 rue Henri et Gilberte Goudier, 63200 Riom, France.",
            "firstname": "Doriane",
            "initials": "D",
            "lastname": "Ripoche"
        },
        {
            "affiliation": "Clinic'n'Cell SAS, Facult\u00e9 de M\u00e9decine, 28 Place Henri Dunant, 63001 Clermont-Ferrand, France.",
            "firstname": "Line",
            "initials": "L",
            "lastname": "Boutin-Wittrant"
        },
        {
            "affiliation": "Valbiotis, 20 rue Henri et Gilberte Goudier, 63200 Riom, France.",
            "firstname": "Yolanda F",
            "initials": "YF",
            "lastname": "Otero"
        },
        {
            "affiliation": "INRAE, INP, Campus ISVV, Universit\u00e9 de Bordeaux-INRAE-INP-ISVV, 210 Chem. de Leysotte, 33140 Villenave-d'Ornon, France.",
            "firstname": "St\u00e9phanie",
            "initials": "S",
            "lastname": "Krisa"
        },
        {
            "affiliation": "MetaboHUB, Bordeaux Metabolome, 210 Chem. de Leysotte, 33140 Villenave-d'Ornon, France.",
            "firstname": "Josep",
            "initials": "J",
            "lastname": "Valls"
        },
        {
            "affiliation": "Valbiotis, Zone Industrielle des 4 Chevaliers, B\u00e2timent 12F, Rue Paul Vatine, 17180 Perigny, France.",
            "firstname": "Mah\u00e9va",
            "initials": "M",
            "lastname": "Maura"
        },
        {
            "affiliation": "Valbiotis, Zone Industrielle des 4 Chevaliers, B\u00e2timent 12F, Rue Paul Vatine, 17180 Perigny, France.",
            "firstname": "Florian",
            "initials": "F",
            "lastname": "Le Joubioux"
        },
        {
            "affiliation": "CNRS, LIENs, Campus NA, La Rochelle Universit\u00e9 CNRS-LIENSs-, 2, Rue Olympe de Gouges, 17000 La Rochelle, France.",
            "firstname": "Thierry",
            "initials": "T",
            "lastname": "Maugard"
        },
        {
            "affiliation": "LAPEC EA-4278, Avignon Universit\u00e9, 228 Route de L'A\u00e9rodrome, 84000 Avignon, France.",
            "firstname": "Ga\u00ebtan",
            "initials": "G",
            "lastname": "Bolea"
        },
        {
            "affiliation": "LAPEC EA-4278, Avignon Universit\u00e9, 228 Route de L'A\u00e9rodrome, 84000 Avignon, France.",
            "firstname": "Gr\u00e9gory",
            "initials": "G",
            "lastname": "Meyer"
        },
        {
            "affiliation": "LAPEC EA-4278, Avignon Universit\u00e9, 228 Route de L'A\u00e9rodrome, 84000 Avignon, France.",
            "firstname": "Cyril",
            "initials": "C",
            "lastname": "Reboul"
        },
        {
            "affiliation": "CIC INSERM 1405/Plateforme d'Investigation Clinique CHU Gabriel Montpied, 63000 Clermont-Ferrand, France.",
            "firstname": "V\u00e9ronique",
            "initials": "V",
            "lastname": "Roux"
        },
        {
            "affiliation": "CIC INSERM 1405/Plateforme d'Investigation Clinique CHU Gabriel Montpied, 63000 Clermont-Ferrand, France.",
            "firstname": "Nicolas",
            "initials": "N",
            "lastname": "Macian"
        },
        {
            "affiliation": "CIC INSERM 1405/Plateforme d'Investigation Clinique CHU Gabriel Montpied, 63000 Clermont-Ferrand, France.",
            "firstname": "Gis\u00e8le",
            "initials": "G",
            "lastname": "Pickering"
        },
        {
            "affiliation": "Biostat Unit, DRCI, CHU, 63000 Clermont-Ferrand, France.",
            "firstname": "Bruno",
            "initials": "B",
            "lastname": "Pereira"
        },
        {
            "affiliation": "Valbiotis, Zone Industrielle des 4 Chevaliers, B\u00e2timent 12F, Rue Paul Vatine, 17180 Perigny, France.",
            "firstname": "Maxime",
            "initials": "M",
            "lastname": "Bargetto"
        },
        {
            "affiliation": "Valbiotis, Zone Industrielle des 4 Chevaliers, B\u00e2timent 12F, Rue Paul Vatine, 17180 Perigny, France.",
            "firstname": "V\u00e9ronique",
            "initials": "V",
            "lastname": "Sapone"
        },
        {
            "affiliation": "Valbiotis, Zone Industrielle des 4 Chevaliers, B\u00e2timent 12F, Rue Paul Vatine, 17180 Perigny, France.",
            "firstname": "Murielle",
            "initials": "M",
            "lastname": "Cazaubiel"
        },
        {
            "affiliation": "Valbiotis, Zone Industrielle des 4 Chevaliers, B\u00e2timent 12F, Rue Paul Vatine, 17180 Perigny, France.",
            "firstname": "S\u00e9bastien",
            "initials": "S",
            "lastname": "Peltier"
        },
        {
            "affiliation": "Valbiotis, 20 rue Henri et Gilberte Goudier, 63200 Riom, France.",
            "firstname": "Pascal",
            "initials": "P",
            "lastname": "Sirvent"
        },
        {
            "affiliation": "Clinic'n'Cell SAS, Facult\u00e9 de M\u00e9decine, 28 Place Henri Dunant, 63001 Clermont-Ferrand, France.\nINRAE, UMR 1019, UNH, 63000 Clermont-Ferrand, France.",
            "firstname": "Yohann",
            "initials": "Y",
            "lastname": "Wittrant"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.3390/nu17081331\n10.1016/s0140-6736(02)11911-8\n10.1161/CIRCRESAHA.116.304723\n10.1161/CIR.0b013e31828124ad\n10.1152/physiol.00026.2016\n10.1097/HJH.0000000000000681\n10.1161/CIRCRESAHA.116.303647\n10.1016/j.cca.2021.10.029\n10.1016/j.phrs.2017.05.020\n10.1038/nm.2541\n10.1161/CIR.0000000000000450\n10.3390/nu15081903\n10.1210/jcem.86.6.7601\n10.3390/ijerph19148373\n10.1155/2016/7432797\n10.1111/bph.13492\n10.3390/antiox9020092\n10.1016/S0024-3205(97)01155-7\n10.1016/j.nut.2019.110579\n10.1097/01.hjh.0000226196.67052.c0\n10.1016/j.biopha.2018.10.044\n10.1515/jbcpp-2019-0360\n10.1007/s00216-019-02323-x\n10.3390/nu14235027\n10.3390/nu14071511\n10.3390/nu13082653\n10.3390/nu11061249\n10.3390/nu11123071\n10.1186/s12891-023-06800-4\n10.3390/antiox12122105\n10.1007/s00394-016-1188-y\n10.1017/S0007114508006867\n10.1016/j.lfs.2004.07.018\n10.1172/JCI107260\n10.1373/clinchem.2011.167361\n10.1093/ajcn/nqy380\n10.1016/j.biopha.2018.03.131\n10.1016/j.jdiacomp.2016.01.003\n10.1002/ptr.6671\n10.1007/s00394-019-01916-7\n10.4103/0975-9476.65073\n10.1016/j.ctim.2020.102322\n10.3390/foods8090358\n10.1016/j.nutres.2009.01.001\n10.1139/Y10-101\n10.1111/jfbc.13126\n10.1093/ecam/nep011\n10.1054/plef.2000.0152\n10.29219/fnr.v63.3361\n10.1016/j.vph.2015.12.003\n10.1002/ptr.6920\n10.1016/j.numecd.2017.10.027\n10.1016/j.atherosclerosis.2015.03.024\n10.1186/1471-2466-12-36",
    "journal": "Nutrients",
    "keywords": [
        "clinical trial",
        "ex vivo",
        "human endothelial cells",
        "human metabolites",
        "hypertension",
        "lipotoxic stress",
        "oxidative stress",
        "plant extract"
    ],
    "methods": null,
    "publication_date": "2025-04-26",
    "pubmed_id": "40284196\n12493255\n25767281\n23239837\n28202622\n26203966\n25767282\n34728179\n28571891\n22064430\n27799274\n37111121\n11397900\n35886227\n27738491\n27058985\n31978956\n9464471\n31743815\n16685206\n30399581\n33001849\n31872275\n36501057\n35406124\n34444810\n31159319\n31888255\n37735385\n38136224\n26951205\n18598589\n15581909\n4348345\n21926181\n31136659\n21033621\n29604599\n26954484\n32180294\n30796508\n21836795\n32147075\n31450776\n19285604\n21186379\n31877235\n19233877\n10882191\n31452653\n26746853\n33098170\n29329924\n25805361\n22824065",
    "results": null,
    "title": "TOTUM-854 Human Circulating Bioactives Preserve Endothelial Cell Function.",
    "xml": "<Element 'PubmedArticle' at 0x788503dfb790>"
}