{
    "abstract": "The decision to terminate a pregnancy due to fetal anomalies can have a significant emotional impact, especially in second-trimester terminations. Previous studies on the psychological consequences of pregnancy termination have had limitations, and little is known about the outcomes for partners and the impact of fetal donation. Therefore, we aimed to investigate the psychological effects of second-trimester pregnancy termination and identify factors associated with outcomes in both women and men, including donation of fetal remains to science.\nA longitudinal cohort study was conducted at the Amsterdam UMC in the Netherlands, involving women and partners who underwent termination at or before 23\u2009weeks and 6\u2009days of gestation. Questionnaires were administered at termination, 6\u2009weeks, and 4\u2009months after. We utilized validated questionnaires to assess psychological morbidity (grief, post-traumatic stress and postnatal depression and quality of life [QoL]), and factors that could potentially influence outcomes.\nOf 241 participants, women displayed more pronounced psychological distress than men, though both groups improved over time. Four months after termination, 27.4% of women and 9.1% of men showed signs of pathological grief. Scores indicative for postnatal depression occurred in 19.8% women and 4.1% of men. A prior psychiatric history was a consistent predictor of poorer outcomes. Fetal donation to the Dutch Fetal Biobank was associated with reduced likelihood of symptoms of complicated grief four months after termination.\nSecond-trimester termination of pregnancy for fetal anomalies can lead to psychological morbidity, particularly in women. However, there is a notable improvement over time for both groups. Individuals with prior psychiatric history appear more vulnerable post-termination. Also, fetal donation to science did not have a negative impact on psychological well-being.",
    "authors": [
        {
            "affiliation": "Department of Medical Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.\nDepartment of Obstetrics and Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.\nAmsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.",
            "firstname": "Yousif",
            "initials": "Y",
            "lastname": "Dawood"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.\nAmsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.",
            "firstname": "Jana M",
            "initials": "JM",
            "lastname": "de Vries"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.\nAmsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.",
            "firstname": "Elisabeth",
            "initials": "E",
            "lastname": "van Leeuwen"
        },
        {
            "affiliation": "Department of Epidemiology and Data Science, Amsterdam UMC, Location VUmc, Amsterdam, the Netherlands.",
            "firstname": "Rik",
            "initials": "R",
            "lastname": "van Eekelen"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.\nAmsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.\nDepartment of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, the Netherlands.",
            "firstname": "Bernadette S",
            "initials": "BS",
            "lastname": "de Bakker"
        },
        {
            "affiliation": "ARQ National Psychotrauma Center, Diemen, the Netherlands.\nDepartment of Clinical Psychology, Utrecht University, Utrecht, the Netherlands.",
            "firstname": "Paul A",
            "initials": "PA",
            "lastname": "Boelen"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.\nAmsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.",
            "firstname": "Eva",
            "initials": "E",
            "lastname": "Pajkrt"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2024 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).",
    "doi": "10.1111/aogs.14848",
    "journal": "Acta obstetricia et gynecologica Scandinavica",
    "keywords": [
        "fetal anomalies",
        "fetal donation",
        "psychological well\u2010being",
        "termination of pregnancy"
    ],
    "methods": null,
    "publication_date": "2024-07-09",
    "pubmed_id": "38978342\n34320417\n15962717\n15791682\n1589421\n17533631\n19560116\n12868079\n16353270\n15791695\n38113849\n8771222\n3651732\n1447427\n9088059\n15085902\n12703504\n2597888\n2224383\n20350638\n25224314\n31519218\n26606250\n23880492\n21357879\n19769749\n23793655\n36609996\n35584590\n21126334",
    "results": "Of 241 participants, women displayed more pronounced psychological distress than men, though both groups improved over time. Four months after termination, 27.4% of women and 9.1% of men showed signs of pathological grief. Scores indicative for postnatal depression occurred in 19.8% women and 4.1% of men. A prior psychiatric history was a consistent predictor of poorer outcomes. Fetal donation to the Dutch Fetal Biobank was associated with reduced likelihood of symptoms of complicated grief four months after termination.",
    "title": "Psychological sequelae following second-trimester termination of pregnancy: A longitudinal study.",
    "xml": "<Element 'PubmedArticle' at 0x7885048dc130>"
}