{
    "abstract": "Oral N-acetylcysteine (NAC) has shown efficacy for debilitating habit-driven and neuropsychiatric disorders in small, mostly adult studies. We retrospectively evaluated the therapeutic use and safety of oral NAC in 93 children from the Children's Hospital of Philadelphia. This study supports the use of oral NAC for habit-driven skin, hair, and nail abnormalities in pediatric patients.",
    "authors": [
        {
            "affiliation": "Albert Einstein College of Medicine, Bronx, New York, USA.\nSection of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.",
            "firstname": "Diana H",
            "initials": "DH",
            "lastname": "Zarowin"
        },
        {
            "affiliation": "Pediatric Dermatology Research Alliance, Portland, Oregon, USA.",
            "firstname": "Amy",
            "initials": "A",
            "lastname": "Buros Stein"
        },
        {
            "affiliation": "Unit on Vascular Malformations, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.",
            "firstname": "Sarah E",
            "initials": "SE",
            "lastname": "Sheppard"
        },
        {
            "affiliation": "Section of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.\nPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.",
            "firstname": "James R",
            "initials": "JR",
            "lastname": "Treat"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2024 Wiley Periodicals LLC.",
    "doi": "10.1111/pde.15852",
    "journal": "Pediatric dermatology",
    "keywords": [
        "hair disorders",
        "pharmacology",
        "psychocutaneous disorders",
        "quality of life",
        "skin barrier"
    ],
    "methods": null,
    "publication_date": "2025-01-17",
    "pubmed_id": "39821896",
    "results": null,
    "title": "A Retrospective Review of Oral N-Acetylcysteine for Habit-Driven Cutaneous Disorders.",
    "xml": "<Element 'PubmedArticle' at 0x7885056ffba0>"
}