{
    "abstract": "Acute right ventricular failure is a complex and rapidly progressive clinical syndrome, whereby the right ventricle fails to provide adequate left ventricular preload, dilates, and causes systemic venous congestion. Previous research in acute heart failure has primarily focused on the left ventricle. Yet, the need for a better understanding of right ventricular anatomy, physiology, and pathophysiology, as well as of the diagnosis and management of its acute failure is crucial. Diagnosis mandates a high degree of clinical suspicion, as the majority of signs and symptoms are nonspecific. An accurate and prompt identification of the underlying causes, including pulmonary embolism, right ventricular myocardial infarction, acute respiratory distress syndrome, post-cardiac surgery, and decompensated chronic pulmonary hypertension, is therefore essential. This review provides insights into right ventricular anatomy and functioning and discusses the pathophysiology of acute right ventricular failure, its differential aetiologies, clinical presentation, diagnosis, and treatment.",
    "authors": [
        {
            "affiliation": "Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Kiriakidi 1, Thessaloniki 54636, Greece.",
            "firstname": "George",
            "initials": "G",
            "lastname": "Giannakoulas"
        },
        {
            "affiliation": "Medizinische Klinik und Poliklinik I, LMU Klinikum, Munich, Germany.\nCenter for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.",
            "firstname": "Ioannis T",
            "initials": "IT",
            "lastname": "Farmakis"
        },
        {
            "affiliation": "Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.\nDepartment of Cardiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.",
            "firstname": "Lukas",
            "initials": "L",
            "lastname": "Hobohm"
        },
        {
            "affiliation": "Centre for Cardiovascular Diseases, University Hospital Brussels, Jette, Belgium.\nFaculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.",
            "firstname": "Frederik H",
            "initials": "FH",
            "lastname": "Verbrugge"
        },
        {
            "affiliation": "Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA.",
            "firstname": "Ryan J",
            "initials": "RJ",
            "lastname": "Tedford"
        },
        {
            "affiliation": "Mount Sinai Heart, Icahn School of Medicine at Mount Sinai Health System, New York, NY, USA.\nCentro Integral de Enfermedades Cardiovasculares (CIEC), Hospital Universitario HM Montepr\u00edncipe, Madrid, Spain.\nAtriaclinic, Madrid, Spain.",
            "firstname": "Javier",
            "initials": "J",
            "lastname": "Sanz"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site\u2014for further information please contact journals.permissions@oup.com.",
    "doi": "10.1093/eurheartj/ehaf215",
    "journal": "European heart journal",
    "keywords": [
        "Acute respiratory distress syndrome",
        "Echocardiography",
        "Failure",
        "Haemodynamic",
        "Intensive care",
        "Mechanical circulatory support",
        "Pulmonary embolism",
        "Pulmonary hypertension",
        "Right ventricle",
        "Right ventricular infarction"
    ],
    "methods": null,
    "publication_date": "2025-04-22",
    "pubmed_id": "40259766",
    "results": null,
    "title": "Acute right ventricular failure: pathophysiology, aetiology, assessment, and management.",
    "xml": "<Element 'PubmedArticle' at 0x788505f538d0>"
}