{
    "abstract": "To evaluate the incidence and course of urinary tract infections (UTI) in patients with multiple sclerosis (MS) and their relationship to the method of bladder evacuation.\nPatients with neurogenic bladder dysfunction due to MS (n=111) were enrolled in the study. During one-year follow-up, clinical examination with urine culture was performed every 4 months or whenever symptoms occurred. The control group included patients with symptomatic UTI, without neurological or autoimmune disease. Incidence of symptomatic and asymptomatic bacteriuria, the effect of urine drainage on UTI incidence, and the effect of antibiotics were statistically evaluated.\n54 MS patients completed the protocol. The mean incidence of symptomatic and asymptomatic bacteriuria in the MS group was 12.5% and 29.6%, respectively. A decreasing trend in the incidence of symptomatic, and an increasing trend in the incidence of asymptomatic bacteriuria was observed. Eradication of UTI in symptomatic MS patients was significantly lower than in controls (37.75% vs. 92.93%, P<0.05). Causative agents significantly differed in both groups (P=0.0005). The hypothesis that the incidence of UTIs in MS patients is independent of the method of bladder evacuation was not rejected (P>0.99 at visit 0, 1 and 3, P=0.078 at visit 2).\nThere is a significant difference between the causative agents of UTI in both groups. Eradication of bacteriuria in symptomatic MS patients is difficult when compared to the normal population. We have insufficient evidence to confirm the relationship between the incidence of UTI and the method of bladder evacuation.",
    "authors": [
        {
            "affiliation": "Department of Urology, University Hospital Brno, Czech Republic; Faculty of Medicine, Masaryk University Brno, Czech Republic.",
            "firstname": "G",
            "initials": "G",
            "lastname": "Varga"
        },
        {
            "affiliation": "Department of Urology, University Hospital Brno, Czech Republic; Faculty of Medicine, Masaryk University Brno, Czech Republic. Electronic address: fedorko.michal@fnbrno.cz.",
            "firstname": "M",
            "initials": "M",
            "lastname": "Fedorko"
        },
        {
            "affiliation": "Department of Urology, University Hospital Brno, Czech Republic; Faculty of Medicine, Masaryk University Brno, Czech Republic.",
            "firstname": "R",
            "initials": "R",
            "lastname": "Wasserbauer"
        },
        {
            "affiliation": "Department of Urology, University Hospital Brno, Czech Republic.",
            "firstname": "J",
            "initials": "J",
            "lastname": "Markusova"
        },
        {
            "affiliation": "Department of Neurology, University Hospital Brno, Czech Republic.",
            "firstname": "P",
            "initials": "P",
            "lastname": "Praksova"
        },
        {
            "affiliation": "Department of Urology, University Hospital Brno, Czech Republic.",
            "firstname": "V",
            "initials": "V",
            "lastname": "Adedokun"
        },
        {
            "affiliation": "Department of Urology, University Hospital Brno, Czech Republic; Faculty of Medicine, Masaryk University Brno, Czech Republic.",
            "firstname": "T",
            "initials": "T",
            "lastname": "Trinh"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2022. Published by Elsevier Espa\u00f1a, S.L.U.",
    "doi": "10.1016/j.acuroe.2022.08.007",
    "journal": "Actas urologicas espanolas",
    "keywords": [
        "Cateterismo",
        "Catheterization",
        "Esclerosis m\u00faltiple",
        "Infecci\u00f3n tracto urinario",
        "Multiple sclerosis",
        "Prevenci\u00f3n",
        "Prevention",
        "Recurrence",
        "Recurrencia",
        "Urinary tract infection"
    ],
    "methods": null,
    "publication_date": "2022-10-11",
    "pubmed_id": "36216764",
    "results": "54 MS patients completed the protocol. The mean incidence of symptomatic and asymptomatic bacteriuria in the MS group was 12.5% and 29.6%, respectively. A decreasing trend in the incidence of symptomatic, and an increasing trend in the incidence of asymptomatic bacteriuria was observed. Eradication of UTI in symptomatic MS patients was significantly lower than in controls (37.75% vs. 92.93%, P<0.05). Causative agents significantly differed in both groups (P=0.0005). The hypothesis that the incidence of UTIs in MS patients is independent of the method of bladder evacuation was not rejected (P>0.99 at visit 0, 1 and 3, P=0.078 at visit 2).",
    "title": "Urinary tract infections in patients with multiple sclerosis and different methods of bladder evacuation.",
    "xml": "<Element 'PubmedArticle' at 0x788504bf7b00>"
}