{
    "abstract": "The etiology of pelvic organ prolapse (POP) likely includes over-distension or tears (avulsion) of the levator ani muscle. However, there is a lack of studies evaluating the association between symptoms of POP and these factors. This study was designed to determine the association between POP symptoms and clinical prolapse stage on the one hand, and pelvic floor functional anatomy on the other hand.\nThis prospective observational study included 258 patients seen at a tertiary urogynecological unit with symptoms of POP as defined by pertinent ICIQ questions. After informed consent and a detailed history including ICIQ responses, 3D transperineal ultrasonography was performed using a GE Voluson i ultrasound system. Offline analysis was performed on de-identified datasets.\nThe mean age of the patients was 60.6\u00a0years (25-91\u00a0years) and their mean BMI was 29.8\u00a0kg/m\nThere is a significant association between awareness, visualization and/or feeling of a vaginal lump and abnormal pelvic floor functional anatomy, that is, hiatal ballooning and levator avulsion.",
    "authors": [
        {
            "affiliation": "Division of Urogynaecology, Department of Obstetrics and Gynaecology, University of Pretoria, Steve Biko Academic Hospital, Pretoria, South Africa. zeelha.abdool@up.ac.za.\nFaculty of Health Sciences, University of Pretoria, Pretoria, South Africa. zeelha.abdool@up.ac.za.",
            "firstname": "Zeelha",
            "initials": "Z",
            "lastname": "Abdool"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, University of Sydney Medical School Nepean, Kingswood, Australia.",
            "firstname": "Hans Peter",
            "initials": "HP",
            "lastname": "Dietz"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, University of Pretoria, Steve Biko Academic Hospital, Pretoria, South Africa.",
            "firstname": "Barend Gerhardus",
            "initials": "BG",
            "lastname": "Lindeque"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1007/s00192-017-3280-0",
    "journal": "International urogynecology journal",
    "keywords": [
        "Levator avulsion",
        "Pelvic organ descent",
        "Prolapse symptoms"
    ],
    "methods": null,
    "publication_date": "2017-02-06",
    "pubmed_id": "28154915\n19399355\n22457009\n20735379\n16709214\n26616261\n17323308\n18503571\n20832929\n16412002\n8694033\n12851756\n21822712\n22050558\n11844174\n24548759\n23278472\n11744905\n9915453\n21951068\n19426956\n16401217\n17267827\n25761589\n15516388\n16199625\n17523155",
    "results": "The mean age of the patients was 60.6\u00a0years (25-91\u00a0years) and their mean BMI was 29.8\u00a0kg/m",
    "title": "Prolapse symptoms are associated with abnormal functional anatomy of the pelvic floor.",
    "xml": "<Element 'PubmedArticle' at 0x788505f60360>"
}