{
    "abstract": "Coronary artery disease remains the largest contributor to cardiac arrests worldwide; yet, long-term outcomes are often driven by neurological status after resuscitation. We examined the association between pre-percutaneous coronary intervention (PCI) level of consciousness (LOC) and outcomes among patients with cardiac arrest who underwent PCI.\nThe study cohort included patients undergoing PCI after cardiac arrest between April 2018 and March 2022 at 48 hospitals in the state of Michigan. Pre-PCI LOC was categorized as mentally alert, partially responsive, unresponsive, and unable to assess. In-hospital outcomes included mortality, bleeding, and acute kidney injury.\nAmong 3021 patients who underwent PCI after cardiac arrest, 1394 (49%) were mentally alert, 132 (5%) were partially responsive, 698 (24%) were unresponsive, and 631 (22%) were unable to assess. The mentally alert cohort had lower mortality (4.59%) compared with the partially responsive (17.42%), unresponsive (50.14%), and unable to assess cohorts (38.03%; \nPre-PCI LOC is a strong predictor of in-hospital outcomes after PCI among cardiac arrest patients. A patient's pre-PCI LOC should be considered an important factor when weighing treatment options, designing clinical trials, and counseling patients and their families regarding prognosis after PCI.",
    "authors": [
        {
            "affiliation": "Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.E.H., D.S.K., M. Seth, H.S.G., D.S.).",
            "firstname": "David E",
            "initials": "DE",
            "lastname": "Hamilton"
        },
        {
            "affiliation": "Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.E.H., D.S.K., M. Seth, H.S.G., D.S.).",
            "firstname": "Daniel S",
            "initials": "DS",
            "lastname": "Kobe"
        },
        {
            "affiliation": "Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.E.H., D.S.K., M. Seth, H.S.G., D.S.).",
            "firstname": "Milan",
            "initials": "M",
            "lastname": "Seth"
        },
        {
            "affiliation": "Covenant Healthcare, Saginaw, MI (M. Sharma).",
            "firstname": "Manoj",
            "initials": "M",
            "lastname": "Sharma"
        },
        {
            "affiliation": "Ascension St. John Hospital, Detroit, MI (T.L.).",
            "firstname": "Thomas",
            "initials": "T",
            "lastname": "LaLonde"
        },
        {
            "affiliation": "McLaren Healthcare, Lansing, MI (I.S.).",
            "firstname": "Ibrahim",
            "initials": "I",
            "lastname": "Shah"
        },
        {
            "affiliation": "Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.E.H., D.S.K., M. Seth, H.S.G., D.S.).",
            "firstname": "Hitinder S",
            "initials": "HS",
            "lastname": "Gurm"
        },
        {
            "affiliation": "Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.E.H., D.S.K., M. Seth, H.S.G., D.S.).",
            "firstname": "Devraj",
            "initials": "D",
            "lastname": "Sukul"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1161/CIRCINTERVENTIONS.124.014189",
    "journal": "Circulation. Cardiovascular interventions",
    "keywords": [
        "cardiac arrest",
        "level of consciousness",
        "odds ratio",
        "percutaneous coronary intervention",
        "treatment"
    ],
    "methods": null,
    "publication_date": "2024-10-15",
    "pubmed_id": "39405370",
    "results": "Among 3021 patients who underwent PCI after cardiac arrest, 1394 (49%) were mentally alert, 132 (5%) were partially responsive, 698 (24%) were unresponsive, and 631 (22%) were unable to assess. The mentally alert cohort had lower mortality (4.59%) compared with the partially responsive (17.42%), unresponsive (50.14%), and unable to assess cohorts (38.03%; ",
    "title": "Association Between Neurological Status and Outcomes in Cardiac Arrest Patients Undergoing PCI in Contemporary Practice: Insights From BMC2.",
    "xml": "<Element 'PubmedArticle' at 0x788502a1c9f0>"
}