{
    "abstract": "This study aimed to evaluate the clinical efficacy of labetalol (LBT) combined with magnesium sulfate (MgSO\nA total of 122 HDP patients admitted between January 2020 and June 2024 were included. Among them, 56 patients (control group) received MgSO\nThe research group demonstrated significantly better outcomes than the control group, including a higher overall therapeutic effectiveness rate, faster resolution of edema, hypertension, and proteinuria, a lower incidence of adverse pregnancy events, and more pronounced reductions in SBP, DBP, S/D, PI, and hs-CRP levels after treatment (all P < 0.05).\nThe combination of LBT and MgSO",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynecology, Ji'an Central People's Hospital Ji'an 343000, Jiangxi, China.",
            "firstname": "Xiaolan",
            "initials": "X",
            "lastname": "Zhuang"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Ji'an Central People's Hospital Ji'an 343000, Jiangxi, China.",
            "firstname": "Xingxing",
            "initials": "X",
            "lastname": "Li"
        },
        {
            "affiliation": "Department of Critical Care Medicine, 908th Hospital of the Joint Logistics Support Force of The Chinese People's Liberation Army Nanchang 330000, Jiangxi, China.",
            "firstname": "Shikai",
            "initials": "S",
            "lastname": "Yu"
        },
        {
            "affiliation": "Department of Neurosurgery, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.",
            "firstname": "Lin",
            "initials": "L",
            "lastname": "Zeng"
        },
        {
            "affiliation": "Department of Neurosurgery, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.",
            "firstname": "Yuping",
            "initials": "Y",
            "lastname": "Xu"
        },
        {
            "affiliation": "Department of General Medicine, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.",
            "firstname": "Tingting",
            "initials": "T",
            "lastname": "Hu"
        },
        {
            "affiliation": "Department of Neurosurgery, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.",
            "firstname": "Sailong",
            "initials": "S",
            "lastname": "Wan"
        }
    ],
    "conclusions": "The combination of LBT and MgSO",
    "copyrights": "AJTR Copyright \u00a9 2025.",
    "doi": "10.62347/TWVI9995",
    "journal": "American journal of translational research",
    "keywords": [
        "Labetalol",
        "brain symptoms",
        "hypertensive disorders of pregnancy",
        "magnesium sulfate",
        "pregnancy outcomes"
    ],
    "methods": null,
    "publication_date": "2025-04-14",
    "pubmed_id": "40225988\n36109676\n35252402\n34135442\n32852628\n29887995\n32199925\n34905954\n30277556\n30222695\n37854216\n24619389\n33770589\n38798818\n38334337\n37308715\n30941817\n33153664\n22828113\n35596590\n36346411\n39292226\n35851172\n33222817\n26158653\n32432770\n29052046\n30237592\n34745277\n29265003\n30224842\n32063925\n33181650\n33200001\n35665288\n23826490\n30186428\n38756909\n37074522\n16978425",
    "results": "The research group demonstrated significantly better outcomes than the control group, including a higher overall therapeutic effectiveness rate, faster resolution of edema, hypertension, and proteinuria, a lower incidence of adverse pregnancy events, and more pronounced reductions in SBP, DBP, S/D, PI, and hs-CRP levels after treatment (all P < 0.05).",
    "title": "Effects of labetalol plus magnesium sulfate on brain symptoms and pregnancy outcomes in hypertensive disorders of pregnancy.",
    "xml": "<Element 'PubmedArticle' at 0x788503ce93f0>"
}