{
    "abstract": "Neonatal venous thrombosis is a rare condition that can be iatrogenic or occur due to viral infections or genetic mutations. Thromboembolic complications are also commonly observed as a result of SARS-CoV-2 infections. They can affect pediatric patients, especially the ones suffering from multisystem inflammatory syndrome in children (MIS-C) or multisystem inflammatory syndrome in neonates (MIS-N). The question remains whether the maternal SARS-CoV-2 infection during pregnancy can lead to thromboembolic complications in fetuses and neonates. We report on a patient born with an embolism in the arterial duct, left pulmonary artery, and pulmonary trunk, who presented several characteristic features of MIS-N, suspecting that the cause might have been the maternal SARS-CoV2 infection in late pregnancy. Multiple genetic and laboratory tests were performed. The neonate presented only with a positive result of IgG antibodies against SARS-CoV-2. He was treated with low molecular weight heparin. Subsequent echocardiographic tests showed that the embolism dissolved. More research is necessary to evaluate the possible neonatal complications of maternal SARS-CoV-2 infection.",
    "authors": [
        {
            "affiliation": "Faculty of Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Gazala",
            "initials": "G",
            "lastname": "Abdulaziz-Opiela"
        },
        {
            "affiliation": "Faculty of Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Anna",
            "initials": "A",
            "lastname": "Sobieraj"
        },
        {
            "affiliation": "II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Greta",
            "initials": "G",
            "lastname": "Sibrecht"
        },
        {
            "affiliation": "Department of Radiology, Nicolaus Copernicus Hospital, 80-803 Gdansk, Poland.",
            "firstname": "Julia",
            "initials": "J",
            "lastname": "Bajdor"
        },
        {
            "affiliation": "Department of Pediatric Cardiology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Bart\u0142omiej",
            "initials": "B",
            "lastname": "Mrozi\u0144ski"
        },
        {
            "affiliation": "II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Zuzanna",
            "initials": "Z",
            "lastname": "Koz\u0142owska"
        },
        {
            "affiliation": "Department of Reproduction, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Rafa\u0142",
            "initials": "R",
            "lastname": "Iciek"
        },
        {
            "affiliation": "II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Katarzyna",
            "initials": "K",
            "lastname": "Wr\u00f3blewska-Seniuk"
        },
        {
            "affiliation": "Department of Reproduction, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Ewa",
            "initials": "E",
            "lastname": "Wender-O\u017cegowska"
        },
        {
            "affiliation": "II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.",
            "firstname": "Tomasz",
            "initials": "T",
            "lastname": "Szczapa"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.3390/ijms24087629\n10.1080/14767058.2020.1743668\n10.1016/j.thromres.2014.05.036\n10.1038/s41372-021-01232-1\n10.1542/peds.2012-0267\n10.3324/haematol.2011.054775\n10.1016/S0022-3476(97)70071-4\n10.1097/HJH.0000000000003213\n10.7759/cureus.27633\n10.1007/s00134-020-06062-x\n10.1182/blood.2020010218\n10.1159/000520537\n10.1038/s41467-020-17436-6\n10.1093/jpids/piaa133\n10.1038/s41392-020-00454-7\n10.1016/j.rmed.2020.106239\n10.1161/CIRCRESAHA.120.317015\n10.1038/s41368-020-0074-x\n10.1002/path.1570\n10.3390/v13040700\n10.1016/j.jbior.2020.100735\n10.1056/NEJMoa2015432\n10.1038/s41577-020-0343-0\n10.1002/rth2.12712\n10.1016/S0140-6736(20)30566-3\n10.1002/jmv.27774\n10.1136/archdischild-2020-321351\n10.1016/j.thromres.2005.01.010\n10.1097/INF.0000000000003131\n10.1007/s00431-022-04377-z\n10.3390/children7070069\n10.1016/j.jaci.2022.09.006\n10.1016/j.jaci.2022.02.028\n10.1016/j.cell.2020.09.016\n10.1172/JCI144554\n10.1038/s41390-022-02029-4\n10.1038/s41591-022-01724-3\n10.3389/fimmu.2021.654587\n10.3389/fped.2022.944743\n10.1080/20469047.2021.1968596\n10.1038/s41418-020-00633-7\n10.1161/CIRCULATIONAHA.121.057394\n10.3389/fcvm.2020.622473\n10.1038/gim.2012.165\n10.2217/bmm-2018-0392\n10.1186/1752-1947-4-284\n10.1007/s00246-008-9349-2\n10.1371/journal.pcbi.1009053\n10.1109/JBHI.2020.3033405",
    "journal": "International journal of molecular sciences",
    "keywords": [
        "COVID-19 complications",
        "SARS-CoV-2",
        "neonatal thrombosis",
        "pulmonary thrombosis"
    ],
    "methods": null,
    "publication_date": "2023-04-28",
    "pubmed_id": "37108791\n32204642\n24953982\n34657144\n22987875\n22133768\n9386668\n35943095\n36072173\n32367170\n33895804\n35220305\n32665677\n33125068\n33361764\n33246294\n32264791\n32094336\n15141377\n33919537\n32773098\n32458111\n32437596\n32439870\n32864262\n35599701\n32171076\n35415903\n33931403\n16709473\n33956761\n35031848\n32630212\n36116582\n35304157\n32966765\n33497356\n35352005\n35177862\n33841438\n36034557\n34488566\n33037393\n35312380\n33415130\n23288205\n31157538\n20731840\n19052800\n34228716\n33095721",
    "results": null,
    "title": "Prenatal and Neonatal Pulmonary Thrombosis as a Potential Complication of SARS-CoV-2 Infection in Late Pregnancy.",
    "xml": "<Element 'PubmedArticle' at 0x7885066a8450>"
}