{
    "abstract": "A prospective, observational study was done at a tertiary care hospital in Western Maharashtra to describe the etiologies, clinical features, diagnosis and prognosis of cerebral venous sinus thrombosis in an Indian population.\n54 patients with clinical and MRI features suggestive of cerebral venous sinus thrombosis (CVST), were studied with detailed clinical evaluation and pro-thrombotic work up. All were followed up monthly for 6 months, to assess the response to therapy and clinical outcomes.\nThe mean age of presentation was 35 years. Headache was the most common presenting symptom (94%) and hemi paresis (22%) was the most common neurological sign. The most common sinus involved was transverse sinus in 77% of cases. In the unprovoked CVST subset (\nCVST is an important yet under recognized cause of intracranial hypertension and stroke in young. Clinical presentation is extremely varied and a high index of suspicion is needed. Magnetic Resonance Imaging (MRI) brain with Magnetic Resonance Venography (MRV) is the current diagnostic modality of choice. Elevated factor VIII and puerperium are the common etiologies in an Indian population. Management with anticoagulants is safe and has excellent clinical outcomes.",
    "authors": [
        {
            "affiliation": "Senior Adviser (Medicine & Neuro), Command Hospital (Air Force), Bengaluru, India.",
            "firstname": "R K",
            "initials": "RK",
            "lastname": "Anadure"
        },
        {
            "affiliation": "Classified Specialist (Medicine & Neuro), INHS Asvini, Mumbai, India.",
            "firstname": "Vinny",
            "initials": "V",
            "lastname": "Wilson"
        },
        {
            "affiliation": "Senior Adviser (Radiology), INHS Asvini, Mumbai, India.",
            "firstname": "Samaresh",
            "initials": "S",
            "lastname": "Sahu"
        },
        {
            "affiliation": "Associate Professor, Department of Medicine, Armed Forces Medical College, Pune 411040, India.",
            "firstname": "Anuj",
            "initials": "A",
            "lastname": "Singhal"
        },
        {
            "affiliation": "Resident (Medicine), INHS Asvini, Mumbai, India.",
            "firstname": "Satish",
            "initials": "S",
            "lastname": "Kota"
        }
    ],
    "conclusions": "CVST is an important yet under recognized cause of intracranial hypertension and stroke in young. Clinical presentation is extremely varied and a high index of suspicion is needed. Magnetic Resonance Imaging (MRI) brain with Magnetic Resonance Venography (MRV) is the current diagnostic modality of choice. Elevated factor VIII and puerperium are the common etiologies in an Indian population. Management with anticoagulants is safe and has excellent clinical outcomes.",
    "copyrights": null,
    "doi": "10.1016/j.mjafi.2017.11.004",
    "journal": "Medical journal, Armed Forces India",
    "keywords": [
        "Cerebral venous thrombosis",
        "Hemorrhagic infarct",
        "Heparin",
        "Venography"
    ],
    "methods": null,
    "publication_date": "2018-11-20",
    "pubmed_id": "30449917\n26053803\n22626695\n15858188\n12069459\n22416902\n20886189\n23518830\n14976332\n18346644\n1557011\n24560376\n12134170\n17239803\n28479793\n27688576\n27407656\n3693287",
    "results": "The mean age of presentation was 35 years. Headache was the most common presenting symptom (94%) and hemi paresis (22%) was the most common neurological sign. The most common sinus involved was transverse sinus in 77% of cases. In the unprovoked CVST subset (",
    "title": "A study of clinical, radiological and etiological profile of cerebral venous sinus thrombosis at a tertiary care center.",
    "xml": "<Element 'PubmedArticle' at 0x7885051936a0>"
}