{
    "abstract": "Chlamydia trachomatis causes the most prevalent bacterial Sexual Transmitted Infection. In pregnant women, untreated chlamydial infections are associated with abortions, premature rupture of membranes, postpartum endometritis, low birth weight and transmission to the newborn. In C\u00f3rdoba, Argentina, there is little knowledge about the prevalence of Chlamydia trachomatis in women in their third trimester of pregnancy, so, the aim of this study was to evaluate Chlamydia trachomatis prevalence and genotypes present in Cordovan pregnant women with different age and socioeconomic status.\nDesign: prospective study. Settings: Women population from Cordoba city, Argentina. Population: Pregnant women having 35 to 37 weeks of gestation. Methods: Five hundred and nine cervical swabs were collected. Each sample was subjected to DNA extraction and PCR for Chlamydia trachomatis using primers NRO/NLO and CTP1/CTP2. Positives samples were sequenced to determine genotype. Main outcome measures: Demographic data of the patients were collected to detect a population at risk for this infection.\nA prevalence of 6.9% (35/509) for Chlamydia trachomatis infection was detected, with 32/295 and 3/214 from pregnant women with low or better economic resources respectively (p = 0,0001). Results showed a significantly increased rate of 11.6% (30/258) in women under 25 years compared with 2% (5/251) in patients over that age (p = 0,00003). Genotype E was the most prevalent.\nWith these results, we can say that pregnant women under 25 years old and low economic resources are one of the populations in which the screening programs of Chlamydia trachomatis should focus.",
    "authors": [
        {
            "affiliation": "Instituto de Virolog\u00eda Doctor Jos\u00e9 Mar\u00eda Vanella, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina.",
            "firstname": "Ana Ximena",
            "initials": "AX",
            "lastname": "Kiguen"
        },
        {
            "affiliation": "Direcci\u00f3n de Especialidades M\u00e9dicas, Municipalidad de C\u00f3rdoba, C\u00f3rdoba, Argentina.",
            "firstname": "Marcela",
            "initials": "M",
            "lastname": "Marram\u00e1"
        },
        {
            "affiliation": "Laboratorios LACE Sociedad An\u00f3nima, C\u00f3rdoba, Argentina.",
            "firstname": "Susana",
            "initials": "S",
            "lastname": "Ruiz"
        },
        {
            "affiliation": "Centro Integral de Ginecolog\u00eda, Obstetricia y Reproducci\u00f3n (CIGOR), C\u00f3rdoba, Argentina.",
            "firstname": "Patricia",
            "initials": "P",
            "lastname": "Estofan"
        },
        {
            "affiliation": "Instituto de Virolog\u00eda Doctor Jos\u00e9 Mar\u00eda Vanella, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina.",
            "firstname": "Ra\u00fal Fernando",
            "initials": "RF",
            "lastname": "Venezuela"
        },
        {
            "affiliation": "Instituto de Virolog\u00eda Doctor Jos\u00e9 Mar\u00eda Vanella, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina.",
            "firstname": "Jessica Paola",
            "initials": "JP",
            "lastname": "Mosmann"
        },
        {
            "affiliation": "Instituto de Virolog\u00eda Doctor Jos\u00e9 Mar\u00eda Vanella, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina.",
            "firstname": "Marina Soledad",
            "initials": "MS",
            "lastname": "Monetti"
        },
        {
            "affiliation": "Centro de Investigaciones en Bioqu\u00edmica Cl\u00ednica e Inmunolog\u00eda (CIBICI-CONICET), Departamento de Bioqu\u00edmica Cl\u00ednica, Facultad de Ciencias Qu\u00edmicas, Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina.",
            "firstname": "Virginia",
            "initials": "V",
            "lastname": "Rivero"
        },
        {
            "affiliation": "Instituto de Virolog\u00eda Doctor Jos\u00e9 Mar\u00eda Vanella, Facultad de Ciencias M\u00e9dicas, Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina.",
            "firstname": "Cecilia Gabriela",
            "initials": "CG",
            "lastname": "Cuffini"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1371/journal.pone.0217245\n10.1097/AOG.0b013e3181e92c54\n10.1783/147118906776276440\n10.1016/j.ajog.2016.07.003\n10.1186/1471-2458-10-505\n10.1371/journal.pone.0141367\n10.1136/sextrans-2014-051531\n10.4103/0255-0857.58728\n10.1097/OLQ.0000000000000460\n10.1093/molbev/mst197\n10.1097/OLQ.0000000000000460\n10.1371/journal.pone.0034794\n10.1016/j.bjid.2013.01.014\n10.1128/IAI.74.1.578-585.2006\n10.1128/IAI.00515-10\n10.1097/01.olq.0000200609.77577.3f\n10.1111/j.1524-4733.2006.00075.x",
    "journal": "PloS one",
    "keywords": [],
    "methods": null,
    "publication_date": "2019-06-01",
    "pubmed_id": "31150440\n25121325\n20664404\n16824301\n27402054\n22621817\n26322229\n20723264\n26505892\n25107711\n11878718\n20061763\n27144177\n27322048\n24132122\n27322048\n22567090\n23282493\n23831212\n30296025\n26224062\n20470049\n20195670\n20181127\n16369014\n20605986\n11034526\n16601656\n16441519",
    "results": "A prevalence of 6.9% (35/509) for Chlamydia trachomatis infection was detected, with 32/295 and 3/214 from pregnant women with low or better economic resources respectively (p = 0,0001). Results showed a significantly increased rate of 11.6% (30/258) in women under 25 years compared with 2% (5/251) in patients over that age (p = 0,00003). Genotype E was the most prevalent.",
    "title": "Prevalence, risk factors and molecular characterization of Chlamydia trachomatis in pregnant women from C\u00f3rdoba, Argentina: A prospective study.",
    "xml": "<Element 'PubmedArticle' at 0x7885053fcd10>"
}