{
    "abstract": "Background and objectives Antimicrobial resistance (AMR)\u00a0is a growing global threat, with carbapenemase-producing Enterobacterales (CPEs) representing a critical public health challenge. Rapid and accurate detection of CPEs is essential for controlling fatal bacterial AMR infections. This study evaluated the performance of MacConkey media supplemented with ertapenem (MacErt1 and MacErt2) for the detection of CPEs. Methods We formulated the media by supplementing MacConkey agar with ertapenem to final concentrations of 0.5 mg/L (MacErt1) and 1 mg/L (MacErt2). The media were assessed using a panel of 26 characterized Enterobacterales, including CPEs harboring oxacillinase (OXA)-48, OXA-181, New Delhi metallo-beta-lactamase (NDM)-5, and ",
    "authors": [
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Ousmane",
            "initials": "O",
            "lastname": "Sow"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Abdoulaye",
            "initials": "A",
            "lastname": "Ciss\u00e9"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Issa",
            "initials": "I",
            "lastname": "Ndiaye"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Elhadj A",
            "initials": "EA",
            "lastname": "Niang"
        },
        {
            "affiliation": "Medical Microbiology, H\u00f4pital de Pikine, Dakar, SEN.",
            "firstname": "Farma T",
            "initials": "FT",
            "lastname": "Kane"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Khoudia",
            "initials": "K",
            "lastname": "Ciss\u00e9"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Adja B",
            "initials": "AB",
            "lastname": "Gueye"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Aminatou A",
            "initials": "AA",
            "lastname": "Bawa"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Cheikh",
            "initials": "C",
            "lastname": "Fall"
        },
        {
            "affiliation": "Microbiology, Institut Pasteur de Dakar, Dakar, SEN.",
            "firstname": "Yakhya",
            "initials": "Y",
            "lastname": "Dieye"
        },
        {
            "affiliation": "Epidemiology and Public Health, World Health Organization Regional Office for Africa (WCARO), Dakar, SEN.",
            "firstname": "Bissoume",
            "initials": "B",
            "lastname": "Sambe"
        },
        {
            "affiliation": "Epidemiology and Public Health, Faculty of Medicine, Pharmacy, and Odonto-Stomatology, Universit\u00e9 Cheikh Anta Diop de Dakar, Dakar, SEN.",
            "firstname": "Abdoulaye",
            "initials": "A",
            "lastname": "Seck"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2024, Sow et al.",
    "doi": "10.7759/cureus.74106",
    "journal": "Cureus",
    "keywords": [
        "amr surveillance",
        "antimicrobial resistance (amr)",
        "carbapenem resistance",
        "carbapenemase-producing enterobacterales (cpes)",
        "macconkey media supplemented with ertapenem",
        "selective media",
        "senegal"
    ],
    "methods": null,
    "publication_date": "2024-12-23",
    "pubmed_id": "39712805\n35065702\n36356348\n27013843\n35063651\n31597748\n23142168\n12101200\n32849351\n30224970\n23478794\n37610183\n21471338\n37623934\n21192883\n37013626\n27593176\n33492641",
    "results": null,
    "title": "Performance of Ertapenem-Supplemented MacConkey Agar (MacErt) for Detecting Carbapenemase-Producing Enterobacterales.",
    "xml": "<Element 'PubmedArticle' at 0x788506133c40>"
}