{
    "abstract": "Background. Transcatheter aortic valve implantation (TAVI) is widely used in high risk patients (pts) with aortic stenosis. Underlying chronic kidney disease implicates a high risk of postprocedural acute kidney injury (AKI). We analyzed its occurrence, impact on hospital stay, and mortality. Methods. 150 consecutive pts underwent TAVI in our institution (mean age 81\u2009\u00b1\u20097 years; logistic EuroSCORE 24\u2009\u00b1\u200915%). AKI definition was a creatinine rise of 26.5\u2009\u03bcmol/L or more within 48 hours postprocedural. Ten patients on chronic hemodialysis were excluded. Results. AKI occurred in 28 pts (20%). Baseline creatinine was higher in AKI pts (126.4\u2009\u00b1\u200959.2\u2009\u03bcmol/L versus 108.7\u2009\u00b1\u200945.1\u2009\u03bcmol/L, P = 0.09). Contrast media use was distributed evenly. Both, 30-day mortality (29% versus 7%, P < 0.0001) and long-term mortality (43% versus 18%, P < 0.0001) were higher; hospital stay was longer in AKI pts (20\u2009\u00b1\u200912 versus 15\u2009\u00b1\u200910 days, P = 0.03). Predicted renal failure calculated STS Score was similar (8.0\u2009\u00b1\u20095.0% [AKI] versus 7.1\u2009\u00b1\u20094.0% [non-AKI], P = 0.32) and estimated lower renal failure rates than observed. Conclusion. AKI remains a frequent complication with increased mortality in TAVI pts. Careful identification of risk factors and development of more suitable risk scores are essential.",
    "authors": [
        {
            "affiliation": "Division of Angiology, Department of Cardiovascular Medicine, University of Muenster, 48149 Muenster, Germany.",
            "firstname": "Katrin",
            "initials": "K",
            "lastname": "Gebauer"
        },
        {
            "affiliation": null,
            "firstname": "Gerhard-Paul",
            "initials": "GP",
            "lastname": "Diller"
        },
        {
            "affiliation": null,
            "firstname": "Gerrit",
            "initials": "G",
            "lastname": "Kaleschke"
        },
        {
            "affiliation": null,
            "firstname": "Gregor",
            "initials": "G",
            "lastname": "Kerckhoff"
        },
        {
            "affiliation": null,
            "firstname": "Nasser",
            "initials": "N",
            "lastname": "Malyar"
        },
        {
            "affiliation": null,
            "firstname": "Matthias",
            "initials": "M",
            "lastname": "Meyborg"
        },
        {
            "affiliation": null,
            "firstname": "Holger",
            "initials": "H",
            "lastname": "Reinecke"
        },
        {
            "affiliation": null,
            "firstname": "Helmut",
            "initials": "H",
            "lastname": "Baumgartner"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1155/2012/483748",
    "journal": "International journal of nephrology",
    "keywords": [],
    "methods": null,
    "publication_date": "2013-02-01",
    "pubmed_id": "23365748\n12831818\n19711031\n12473543\n18402894\n12822153\n18987758\n21184545\n17180572\n16503954\n16931213\n15882252\n17331245\n10456395\n20037180\n21473973\n21087750\n21061244\n19211648\n22390156\n21186126\n17699187\n19153273\n22219473\n20152233",
    "results": null,
    "title": "The risk of acute kidney injury and its impact on 30-day and long-term mortality after transcatheter aortic valve implantation.",
    "xml": "<Element 'PubmedArticle' at 0x78850336a7a0>"
}