{
    "abstract": "Men are likely at greater risk for heat-induced acute kidney injury compared with women, possibly due to differences in vascular control. We tested the hypothesis that the renal vasoconstrictor and vasodilator responses will be greater in younger women compared with men during passive heat stress. Twenty-five healthy adults [12 women (early follicular phase) and 13 men] completed two experimental visits, heat stress or normothermic time-control, assigned in a block-randomized crossover design. During heat stress, participants wore a water-perfused suit perfused with 50\u00b0C water. Core temperature was increased by \u223c0.8\u00b0C in the first hour before commencing a 2-min cold pressor test (CPT). Core temperature remained clamped and at 1-h post-CPT, subjects ingested a whey protein shake (1.2 g of protein/kg body wt), and measurements were taken pre-, 75 min, and 150 min post-protein. Beat-to-beat blood pressure (Penaz method) was measured and segmental artery vascular resistance (VR, Doppler ultrasound) was calculated as segmental artery blood velocity \u00f7 mean arterial pressure. CPT-induced increases in segmental artery VR did not differ between trials (trial effect: ",
    "authors": [
        {
            "affiliation": "Department of Kinesiology, H.H. Morris Human Performance Laboratories, Indiana University School of Public Health, Bloomington, Indiana, United States.",
            "firstname": "Jessica A",
            "initials": "JA",
            "lastname": "Freemas"
        },
        {
            "affiliation": "Department of Exercise and Nutrition Sciences, Center for Research and Education in Special Environments, University at Buffalo, Buffalo, New York, United States.",
            "firstname": "Morgan L",
            "initials": "ML",
            "lastname": "Worley"
        },
        {
            "affiliation": "Department of Kinesiology, H.H. Morris Human Performance Laboratories, Indiana University School of Public Health, Bloomington, Indiana, United States.",
            "firstname": "Mikaela C",
            "initials": "MC",
            "lastname": "Gabler"
        },
        {
            "affiliation": "Department of Kinesiology, H.H. Morris Human Performance Laboratories, Indiana University School of Public Health, Bloomington, Indiana, United States.\nDepartment of Exercise and Nutrition Sciences, Center for Research and Education in Special Environments, University at Buffalo, Buffalo, New York, United States.",
            "firstname": "Hayden W",
            "initials": "HW",
            "lastname": "Hess"
        },
        {
            "affiliation": "Department of Kinesiology, H.H. Morris Human Performance Laboratories, Indiana University School of Public Health, Bloomington, Indiana, United States.",
            "firstname": "Curtis S",
            "initials": "CS",
            "lastname": "Goss"
        },
        {
            "affiliation": "Department of Kinesiology, H.H. Morris Human Performance Laboratories, Indiana University School of Public Health, Bloomington, Indiana, United States.",
            "firstname": "Tyler B",
            "initials": "TB",
            "lastname": "Baker"
        },
        {
            "affiliation": "Department of Kinesiology, H.H. Morris Human Performance Laboratories, Indiana University School of Public Health, Bloomington, Indiana, United States.",
            "firstname": "Blair D",
            "initials": "BD",
            "lastname": "Johnson"
        },
        {
            "affiliation": "Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts, United States.\nMilitary Performance Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts, United States.\nOak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States.",
            "firstname": "Christopher L",
            "initials": "CL",
            "lastname": "Chapman"
        },
        {
            "affiliation": "Department of Kinesiology, H.H. Morris Human Performance Laboratories, Indiana University School of Public Health, Bloomington, Indiana, United States.",
            "firstname": "Zachary J",
            "initials": "ZJ",
            "lastname": "Schlader"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1152/ajprenal.00034.2024\n10.1016/j.scitotenv.2017.10.207\n10.1159/000520324\n10.1152/ajprenal.00049.2017\n10.1152/ajprenal.00320.2020\n10.1080/23328940.2020.1826841\n10.1113/EP088637\n10.1152/japplphysiol.00601.2021\n10.1038/s41598-017-09630-2\n10.1152/ajpregu.00503.2009\n10.1113/EP087232\n10.1152/japplphysiol.00292.2010\n10.14814/phy2.13988\n10.1152/japplphysiol.00728.2023\n10.1042/cs0740011\n10.3758/bf03193146\n10.1152/ajpregu.00090.2022\n10.5414/CN108497\n10.1007/s00726-018-2640-5\n10.1053/j.ajkd.2017.07.011\n10.1093/ckj/sfy022\n10.1113/EP086865\n10.1152/japplphysiol.00813.2019\n10.1152/japplphysiol.00403.2019\n10.3389/fphys.2018.01928\n10.1152/ajpheart.00214.2003\n10.1152/ajprenal.1986.250.4.F613\n10.1016/S0140-6736(11)61454-2\n10.1016/j.jacc.2005.08.071\n10.1016/j.autneu.2015.12.005\n10.1152/ajpheart.00746.2013\n10.1152/ajpregu.00237.2020\n10.1111/micc.12208\n10.1249/MSS.0000000000003300\n10.1152/japplphysiol.00394.2013\n10.1152/ajprenal.00584.2018",
    "journal": "American journal of physiology. Renal physiology",
    "keywords": [
        "heat stress",
        "oral protein load",
        "renal vasoconstriction",
        "renal vasodilation",
        "sex differences"
    ],
    "methods": null,
    "publication_date": "2024-03-28",
    "pubmed_id": "38545652\n29089137\n34864733\n28679590\n33135479\n33997113\n32495481\n35616302\n28947737\n20702799\n30578582\n20798269\n30659773\n38205553\n3338249\n17695343\n35816723\n27285313\n30167963\n29074166\n30288259\n29450933\n32027544\n31414950\n30687130\n12750063\n3963200\n22617274\n16458147\n8944826\n26723547\n24322616\n33074016\n25996650\n37772882\n23823149\n30565997",
    "results": null,
    "title": "Renal vascular control during normothermia and passive heat stress does not differ between healthy younger men and women.",
    "xml": "<Element 'PubmedArticle' at 0x78850662c590>"
}