{
    "abstract": "ECMO is an escalation treatment for hypoxic respiratory failure in patients with CDH. Open repair has been advocated after ECMO indicating that physiological changes associated to thoracoscopic repair were not well tolerated.\nWe have performed a retrospective review of all patients who underwent ECMO prior CDH repair over a 7\u00a0year period (2015-2021). Outcome measures were intra-operative Ph, PCO\nEleven patients required ECMO prior CDH repair. Six of eleven (55%) were done thoracoscopically (Group A) and five of eleven (45%) via laparotomy (Group B). Two of six (33%) patients (Group A) were converted to a laparotomy, one of six (16%) patient developed a recurrence, and there was no recurrence in Group B. Two of five (40%) patients died within the first 60\u00a0days of life, whilst there was no death in Group A. Intra-operative values are shown below.\nWhilst this is a preliminary report of a limited number of patients, there is no obvious difference of intra-operative blood gas parameters during surgical repair in patients after ECMO. Thoracoscopic CDH repair may be considered in patients after ECMO.",
    "authors": [
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK.",
            "firstname": "Annita",
            "initials": "A",
            "lastname": "Budzanowski"
        },
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK.\nZayed Centre for Research, UCL Institute of Child Health London, 30 Guilford Street, London, WC1N 1EH, UK.",
            "firstname": "Stavros",
            "initials": "S",
            "lastname": "Loukogeorgakis"
        },
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK.",
            "firstname": "Dhanya",
            "initials": "D",
            "lastname": "Mullassery"
        },
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK.",
            "firstname": "Simon",
            "initials": "S",
            "lastname": "Blackburn"
        },
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK.",
            "firstname": "Joe",
            "initials": "J",
            "lastname": "Curry"
        },
        {
            "affiliation": "Anaesthesia Department, Great Ormond Street Hospital for Children, London, UK.",
            "firstname": "Ioannis",
            "initials": "I",
            "lastname": "Ioannou"
        },
        {
            "affiliation": "Anaesthesia Department, Great Ormond Street Hospital for Children, London, UK.",
            "firstname": "Usman",
            "initials": "U",
            "lastname": "Ali"
        },
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK.",
            "firstname": "Kate",
            "initials": "K",
            "lastname": "Cross"
        },
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK.",
            "firstname": "Stefano",
            "initials": "S",
            "lastname": "Giuliani"
        },
        {
            "affiliation": "Great Ormond Street Hospital for Children, SNAPS, London, UK. p.decoppi@ucl.ac.uk.\nZayed Centre for Research, UCL Institute of Child Health London, 30 Guilford Street, London, WC1N 1EH, UK. p.decoppi@ucl.ac.uk.",
            "firstname": "Paolo",
            "initials": "P",
            "lastname": "De Coppi"
        }
    ],
    "conclusions": "Whilst this is a preliminary report of a limited number of patients, there is no obvious difference of intra-operative blood gas parameters during surgical repair in patients after ECMO. Thoracoscopic CDH repair may be considered in patients after ECMO.",
    "copyrights": "\u00a9 2023. The Author(s).",
    "doi": "10.1007/s00383-022-05312-x\n10.1053/j.semperi.2019.07.005\n10.1097/SLA.0b013e31828fab55\n10.1007/s00268-013-2189-0\n10.1089/lap.2015.0243\n10.1016/j.jpedsurg.2008.11.030\n10.1016/j.jpedsurg.2005.05.036\n10.1089/lap.2016.0583\n10.1089/lap.2009.0129\n10.1016/j.jpedsurg.2008.10.013\n10.1055/s-0040-1703011\n10.3389/fped.2022.846630\n10.1016/j.jpedsurg.2017.03.011\n10.1016/j.jpedsurg.2011.03.050\n10.1002/uog.20216",
    "journal": "Pediatric surgery international",
    "keywords": [
        "CDH",
        "ECMO",
        "Minimal invasive surgery",
        "Neonates"
    ],
    "methods": null,
    "publication_date": "2023-01-17",
    "pubmed_id": "36645513\n31472951\n23604057\n23963346\n26488724\n19735811\n16150335\n29641364\n19670981\n19159722\n32146718\n35656380\n28359590\n21683215\n30640410",
    "results": "Eleven patients required ECMO prior CDH repair. Six of eleven (55%) were done thoracoscopically (Group A) and five of eleven (45%) via laparotomy (Group B). Two of six (33%) patients (Group A) were converted to a laparotomy, one of six (16%) patient developed a recurrence, and there was no recurrence in Group B. Two of five (40%) patients died within the first 60\u00a0days of life, whilst there was no death in Group A. Intra-operative values are shown below.",
    "title": "Thoracoscopic vs open repair of congenital diaphragmatic hernia after extracorporeal membrane oxygenation: a comparison of intra-operative data.",
    "xml": "<Element 'PubmedArticle' at 0x788503677100>"
}