{
    "abstract": "A postpartum woman in her 40s, with a history of peripartum cardiomyopathy, developed neutropenic sepsis after a caesarean section and hysterectomy for placenta previa. She presented with high fever, respiratory distress, and splenomegaly, along with severe neutropenia (absolute neutrophil count <100\u2009cells/mm\u00b3). Blood cultures showed coagulase-negative staphylococci, and viral tests were positive for cytomegalovirus (CMV). A suspected complication of haemophagocytic lymphohistiocytosis (HLH) following CMV infection was considered. Broad-spectrum antibiotics, corticosteroids, granulocyte-macrophage colony-stimulating factor and intravenous immunoglobulin were administered. There was marked improvement as the patient became afebrile, with the return of neutrophils and stabilisation of her vital parameters. Follow-up at 3 and 6 months post-admission showed that the patient remained clinically improved with no subsequent complications. This case highlights the challenging management of neutropenic sepsis complicated by HLH provoked by CMV in a postpartum woman.",
    "authors": [
        {
            "affiliation": "Department of General Medicine, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India akashparuthi98@gmail.com.",
            "firstname": "Akash",
            "initials": "A",
            "lastname": "Paruthi"
        },
        {
            "affiliation": "Department of General Medicine, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India.",
            "firstname": "Swati",
            "initials": "S",
            "lastname": "Srivastava"
        },
        {
            "affiliation": "Department of General Medicine, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, India.",
            "firstname": "Rajendra Kumar",
            "initials": "RK",
            "lastname": "Kasana"
        },
        {
            "affiliation": "Department of Hematology, Sawai Man singh Medical College and Hospital, Jaipur, Rajasthan, India.",
            "firstname": "Vishnu",
            "initials": "V",
            "lastname": "Sharma"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 BMJ Publishing Group Limited 2025. No commercial re-use. See rights and permissions. Published by BMJ Group.",
    "doi": "10.1136/bcr-2024-264486",
    "journal": "BMJ case reports",
    "keywords": [
        "Adult intensive care",
        "Haematology (drugs and medicines)",
        "Immunohistochemistry",
        "Infection control in hospital"
    ],
    "methods": null,
    "publication_date": "2025-03-29",
    "pubmed_id": "40154548",
    "results": null,
    "title": "Neutropenic sepsis and CMV-induced haemophagocytic lymphohistiocytosis in the postpartum period.",
    "xml": "<Element 'PubmedArticle' at 0x788505ec9440>"
}