{
    "abstract": "To study outcomes and complications during pregnancy and at delivery in women with a posterior deep infiltrating endometriosis (DIE) nodule persisting after surgery and diagnosed at transvaginal sonography (TVS) in comparison with a control group of women without endometriosis.\nMulticenter observational and cohort study.\nUniversity hospital.\nWomen (n = 200) with a posterior DIE nodule equal or more than 2\u00a0cm\u00a0centimeters in size who desired a pregnancy and a control group of women (n = 300) with no previous recorded diagnosis of endometriosis who delivered in our clinic during the same time period.\nPatient data collected from medical charts and by phone interviews.\nEvaluation of complications during pregnancy and delivery.\nOf the 101 women with a posterior DIE nodule, 52 become pregnant among whom 25 used assisted reproductive technology. Of these 52 pregnancies, 11 ended in an early abortion, and 41 delivered a baby; 13 (31.7%) had a premature delivery, 7 (17.8%) a placenta praevia, and 28 (68.2%) had a cesarean delivery. When compared with the control group, the women with endometriosis had a higher risk of pregnancy complicated by preterm birth, placenta previa, placental abruption, and hypertension. Cesarean delivery and complications during surgery (hysterectomy, hemoperitoneum, and bladder injuries) were statistically significantly more frequent in women with endometriosis than in controls.\nWomen with an incomplete removal of posterior DIE have a high complications rate during pregnancy and delivery.",
    "authors": [
        {
            "affiliation": "Department of Biomedicine and Prevention Obstetrics and Gynecological Clinic, University of Rome \"Tor Vergata,\" Rome, Italy. Electronic address: caterinaexacoustos@tiscali.it.",
            "firstname": "Caterina",
            "initials": "C",
            "lastname": "Exacoustos"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, University of Parma, Parma, Italy.",
            "firstname": "Ilaria",
            "initials": "I",
            "lastname": "Lauriola"
        },
        {
            "affiliation": "Department of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.",
            "firstname": "Lucia",
            "initials": "L",
            "lastname": "Lazzeri"
        },
        {
            "affiliation": "Department of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.",
            "firstname": "Giovanna",
            "initials": "G",
            "lastname": "De Felice"
        },
        {
            "affiliation": "Department of Biomedicine and Prevention Obstetrics and Gynecological Clinic, University of Rome \"Tor Vergata,\" Rome, Italy.",
            "firstname": "Errico",
            "initials": "E",
            "lastname": "Zupi"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.",
    "doi": "10.1016/j.fertnstert.2016.06.024",
    "journal": "Fertility and sterility",
    "keywords": [
        "Complications at delivery",
        "deep infiltrating endometriosis (DIE)",
        "pregnancy complications",
        "transvaginal ultrasound (TVS)"
    ],
    "methods": null,
    "publication_date": "2016-07-23",
    "pubmed_id": "27445198",
    "results": null,
    "title": "Complications during pregnancy and delivery in women with untreated rectovaginal deep infiltrating endometriosis.",
    "xml": "<Element 'PubmedArticle' at 0x788504887fb0>"
}