{
    "abstract": "Trigeminal neuralgia (TN) is characterized by episodic electric, shock-like facial pain. Though often idiopathic, herpes simplex virus type 1 (HSV-1) reactivation can rarely cause symptomatic TN. We report the case of a 30-year-old woman who developed oral HSV-1 lesions followed by right-sided TN pain. MRI of the brain did not reveal neurovascular compression. TN pain completely resolved with oral acyclovir treatment alone, without anticonvulsants. This highlights the importance of considering atypical etiologies such as HSV-1 reactivation in TN evaluation. Early antiviral therapy may treat underlying inflammation and provide sustained symptom relief in HSV-associated TN.",
    "authors": [
        {
            "affiliation": "Family Medicine, Jazan Health Cluster, Jazan, SAU.",
            "firstname": "Amal J",
            "initials": "AJ",
            "lastname": "Alfaifi"
        },
        {
            "affiliation": "Family Medicine, Armed Forces Hospital, Jazan, SAU.",
            "firstname": "Ohood S",
            "initials": "OS",
            "lastname": "Wasli"
        },
        {
            "affiliation": "Faculty of Medicine, Jazan University, Jazan, SAU.",
            "firstname": "Thamer M",
            "initials": "TM",
            "lastname": "Almalki"
        },
        {
            "affiliation": "Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, SAU.",
            "firstname": "Ahmad Y",
            "initials": "AY",
            "lastname": "Alqassim"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2024, Alfaifi et al.",
    "doi": "10.7759/cureus.54128",
    "journal": "Cureus",
    "keywords": [
        "trigeminal neuralgia",
        "\u200facyclovir",
        "\u200fantiviral therapy",
        "\u200ffacial pain",
        "\u200fherpes simplex virus type 1"
    ],
    "methods": null,
    "publication_date": "2024-03-15",
    "pubmed_id": "38487110\n27306631\n28076964\n17997704\n16243236\n24534115\n26510007\n22150699\n18627418\n29489260\n30863282\n11855629\n20874010\n18343328\n18721143\n26175877\n29632753\n35991701",
    "results": null,
    "title": "Trigeminal Neuralgia Secondary to Herpes Simplex Virus Type 1 Infection Treated With Oral Acyclovir.",
    "xml": "<Element 'PubmedArticle' at 0x788501c56e80>"
}