{
    "abstract": "Cancer-associated thrombosis is the second leading cause of death in cancer patients, and its incidence has been increasing in recent years. This survey was aimed at gathering information regarding the management of thromboembolic prophylaxis within the MITO (Multicenter Italian Trials in Ovarian Cancer)-MaNGO (Mario Negri Gynecologic Oncology) groups. We designed a self-administered, multiple-choice online questionnaire available only for MITO-MaNGO members for one month, starting in May 2022 and ending in June 2022. We processed one response form per center, and 50 responses were analyzed, with most of the respondents (78%) over 40 years old. We found that 82% of them consider thromboembolic prophylaxis in gynecologic oncology to be relevant. In 82% of the centers, a standardized protocol on venous thromboembolism (VTE) prophylaxis is used, which is applied to both patients undergoing surgery and those undergoing chemotherapy. In the remaining 18% of centers, prophylaxis is used exclusively for patients undergoing chemotherapy treatment. Prophylaxis of patients undergoing surgery and chemotherapy treatment is managed in most cases by the surgeon (72%) and oncologist (76%), respectively. Only 26% of respondents use a thromboembolic risk assessment scale, and of these, those used are the Caprini Score (6%), Khorana Score (6%), and Wells Score (2%). The respondents have good knowledge of low-molecular-weight heparin (90%) and average knowledge of dicumarolics (40%), direct oral anticoagulants (DOACs) (68%), and antiplatelet agents (40%). The results of our survey indicate that there is a good awareness of thromboembolic prophylaxis in gynecologic oncology. Nevertheless, it is used less in outpatients than in patients undergoing surgery. Moreover, the thromboembolic risk assessment scores are barely used.",
    "authors": [
        {
            "affiliation": "Obstetrics and Gynecology Unit, University of Bari \"Aldo Moro\", 70124 Bari, Italy.",
            "firstname": "Michele",
            "initials": "M",
            "lastname": "Mongelli"
        },
        {
            "affiliation": "Division of Gynecologic Oncology, Fondazione Policlinico Universitario A. Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS, 00168 Rome, Italy.",
            "firstname": "Domenica",
            "initials": "D",
            "lastname": "Lorusso"
        },
        {
            "affiliation": "Department of Gynecologic Oncology, Istituto Europeo di Oncologia, 20141 Milan, Italy.",
            "firstname": "Vanna",
            "initials": "V",
            "lastname": "Zanagnolo"
        },
        {
            "affiliation": "Department of Urology and Gynecology, Istituto Nazionale Tumori, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS, Fondazione G. Pascale, 80131 Naples, Italy.",
            "firstname": "Sandro",
            "initials": "S",
            "lastname": "Pignata"
        },
        {
            "affiliation": "Gynecologic Oncology Program, European Institute of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS, 20139 Milan, Italy.\nSchool of Medicine and Surgery, University of Milan-Bicocca, 20126 Milan, Italy.",
            "firstname": "Nicoletta",
            "initials": "N",
            "lastname": "Colombo"
        },
        {
            "affiliation": "S.S.D. Ginecologia Oncologica Clinicizzata, IRCCS Istituto Tumori \"Giovanni Paolo II\", 70124 Bari, Italy.\nDepartment of Interdisciplinary Medicine (DIM), University of Bari \"Aldo Moro\", 70124 Bari, Italy.",
            "firstname": "Gennaro",
            "initials": "G",
            "lastname": "Cormio"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.3390/diagnostics14111159\n10.1038/s41569-022-00787-6\n10.21037/cdt.2017.09.01\n10.1136/bmj-2022-072715\n10.3390/cancers12051291\n10.1097/IGC.0000000000001111\n10.1016/j.ajog.2016.04.034\n10.1016/j.thromres.2013.01.027\n10.1097/AOG.0000000000000866\n10.1016/j.ygyno.2014.04.046\n10.1186/s13643-021-01814-2\n10.1136/esmoopen-2017-000188\n10.1378/chest.10-1944\n10.1016/j.amjmed.2015.10.027\n10.1016/j.amjmed.2016.03.031\n10.1136/bmjopen-2020-045672\n10.1016/j.thromres.2018.02.004\n10.1016/j.annonc.2022.12.014\n10.1136/bmjoq-2023-002267\n10.1016/S2352-3026(18)30111-X\n10.1097/AOG.0000000000004446\n10.3390/cancers14102439\n10.1016/j.ygyno.2020.11.020\n10.1016/j.thromres.2021.06.021\n10.1001/jamanetworkopen.2020.7410\n10.18632/oncotarget.13620\n10.1055/s-0040-1718927\n10.1016/j.ejca.2015.07.012\n10.1016/j.jogc.2021.05.010\n10.1155/2020/2374716\n10.1056/NEJMoa1814630\n10.1634/theoncologist.2019-0676\n10.1111/jth.15607\n10.1161/JAHA.114.001152\n10.1002/rth2.12431\n10.1016/j.ygyno.2023.01.012\n10.1007/s00345-019-02705-x",
    "journal": "Diagnostics (Basel, Switzerland)",
    "keywords": [
        "gynecology oncology",
        "prophylaxis",
        "venous thromboembolism"
    ],
    "methods": null,
    "publication_date": "2024-06-19",
    "pubmed_id": "38893685\n36258120\n29399531\n37263632\n32443753\n28930804\n27131583\n23433998\n26000507\n24793732\n34625092\n28761749\n21436241\n26551977\n27107925\n34326045\n29703486\n34666313\n36638869\n37832969\n30172343\n34259485\n35626045\n33257014\n34332213\n32589230\n27901494\n10908501\n33482681\n26238017\n34087490\n32963543\n30786186\n32384216\n34822215\n25404191\n33134786\n36701837\n30840115",
    "results": null,
    "title": "Venous Thromboembolism Prophylaxis in Gynecologic Oncology: A MITO-MaNGO Survey.",
    "xml": "<Element 'PubmedArticle' at 0x7885060783b0>"
}