{
    "abstract": "Analgesic efficacy and safety of continuous catheter technique in transmuscular quadratus lumborum block (QLB3) for laparoscopic nephrectomy has not been studied. This study was planned to evaluate the efficacy and safety of ultrasound (US)-guided continuous QLB3 for postoperative analgesia after laparoscopic nephrectomy.\nIn this randomized, open-label, single-centered trial, 64 patients belonging to the American Society of Anesthesiologists, physical status grade I and II, 18-65 years of age, scheduled for laparoscopic nephrectomy were included. Patients were randomized into the QLB group and the control group. After surgery, the QLB group received transmuscular QLB with a 0.4 mL/kg bolus of 0.25% ropivacaine and catheter insertion for continuous infusion of 0.25% ropivacaine at 0.1 mL/kg/h. Patients in both groups received fentanyl (0.5 \u03bcg/kg) as rescue analgesia by IV PCA pump.\nThe data of 30 patients in each group were analyzed. Total fentanyl consumption during the first 48 h postoperatively was significantly lower in the QLB group compared to the control group (mean \u00b1 SD; QLB group = 74.33 \u00b1 32.75 \u03bcg; control group = 209.10 \u00b1 52.04 \u03bcg) (\nUS-guided continuous catheter transmuscular QLB reduced postoperative opioid consumption by 64.45% and decreased NRS pain scores after laparoscopic nephrectomy without complications.",
    "authors": [
        {
            "affiliation": "Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Kamlesh",
            "initials": "K",
            "lastname": "Kumari"
        },
        {
            "affiliation": "Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Nidhi",
            "initials": "N",
            "lastname": "Jain"
        },
        {
            "affiliation": "Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Darshana K",
            "initials": "DK",
            "lastname": "Rathod"
        },
        {
            "affiliation": "Department of Anaesthesiology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.",
            "firstname": "Rashmi",
            "initials": "R",
            "lastname": "Syal"
        },
        {
            "affiliation": "Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Tanvi",
            "initials": "T",
            "lastname": "Meshram"
        },
        {
            "affiliation": "Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Ankur",
            "initials": "A",
            "lastname": "Sharma"
        },
        {
            "affiliation": "Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Manbir",
            "initials": "M",
            "lastname": "Kaur"
        },
        {
            "affiliation": "Department of Urology, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Mahendra",
            "initials": "M",
            "lastname": "Singh"
        },
        {
            "affiliation": "Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.",
            "firstname": "Pradeep",
            "initials": "P",
            "lastname": "Bhatia"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright: \u00a9 2025 Journal of Anaesthesiology Clinical Pharmacology.",
    "doi": "10.4103/joacp.joacp_469_23",
    "journal": "Journal of anaesthesiology, clinical pharmacology",
    "keywords": [
        "Analgesia",
        "nephrectomy",
        "nerve block",
        "postoperative pain"
    ],
    "methods": null,
    "publication_date": "2025-03-03",
    "pubmed_id": "40026741\n23150820\n16686768\n12402719\n29553279\n31791571\n26735154\n27755488\n28277325\n30688787\n31805855\n33106280\n17065895\n26276164\n31412770\n26735154\n26225500\n33542562\n35863995\n33399384\n28549524",
    "results": "The data of 30 patients in each group were analyzed. Total fentanyl consumption during the first 48 h postoperatively was significantly lower in the QLB group compared to the control group (mean \u00b1 SD; QLB group = 74.33 \u00b1 32.75 \u03bcg; control group = 209.10 \u00b1 52.04 \u03bcg) (",
    "title": "The efficacy and safety of continuous transmuscular quadratus lumborum block for postoperative analgesia after laparoscopic nephrectomy: A prospective randomized clinical trial.",
    "xml": "<Element 'PubmedArticle' at 0x788505b88860>"
}