{
    "abstract": "To evaluate the long-term efficacy and safety of ultrasound-guided warm needle knife therapy for patients with advanced knee osteoarthritis (KOA).\nA total of 70 advanced KOA patients were recruited from the Department of Pain and Rehabilitation of the Third Hospital of Wuhan from June 2020 to June 2022. They were randomized to a treatment group or a control group in a 1\u22361 ratio. Patients in the treatment group received ultrasound guided warm needle knife treatment, while patients in the control group received ultrasound guided radiofrequency treatment of the knee sensory plexus, both for 1 time. The primary outcome was the changes in Western Ontario McMaster University Osteoarthritis Index (WOMAC) scores. Other outcomes included the Visual Analogue Pain Scale (VAS) scores, value of Young's modulus of A-shi points, proportion of patients achieving improvement, and adverse events related to study interventions.\nCompared with baseline, the WOMAC and VAS scores in the two groups were significantly decreased at each timepoints(\nUltrasound guided warm needle knife is effective in improving the function of knee joint and relieving pain in patients with advanced KOA. Further, the long-term efficacy of ultrasound guided warm needle knife for advanced KOA was superior to the ultrasound guided radiofrequency therapy.",
    "authors": [
        {
            "affiliation": "Department of Pain and Rehabilitation, The Third Hospital of Wuhan, Wuhan 430000, China.",
            "firstname": "Jing",
            "initials": "J",
            "lastname": "Yin"
        },
        {
            "affiliation": "Department of Pain and Rehabilitation, The Third Hospital of Wuhan, Wuhan 430000, China.",
            "firstname": "Shi-Ru",
            "initials": "SR",
            "lastname": "Ju"
        },
        {
            "affiliation": "Department of Pain and Rehabilitation, The Third Hospital of Wuhan, Wuhan 430000, China.",
            "firstname": "Xiao-Juan",
            "initials": "XJ",
            "lastname": "Luo"
        },
        {
            "affiliation": "Department of Pain and Rehabilitation, The Third Hospital of Wuhan, Wuhan 430000, China.",
            "firstname": "Yi-Xuan",
            "initials": "YX",
            "lastname": "Duan"
        },
        {
            "affiliation": "Department of Pain and Rehabilitation, The Third Hospital of Wuhan, Wuhan 430000, China. 37590328@qq.com.",
            "firstname": "Zhao-Qing",
            "initials": "ZQ",
            "lastname": "Zhang"
        },
        {
            "affiliation": "Department of Traditional Chinese Medicine, Wuhan Dongxihu District People's Hospital, Wuhan 430000. 1610915384@qq.com.",
            "firstname": "Hui-Jun",
            "initials": "HJ",
            "lastname": "Chen"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.13702/j.1000-0607.20231059",
    "journal": "Zhen ci yan jiu = Acupuncture research",
    "keywords": [
        "Advanced knee osteoarthritis",
        "Radio frequency therapy",
        "Ultrasound guidance",
        "Warm needle knife"
    ],
    "methods": null,
    "publication_date": "2025-04-23",
    "pubmed_id": "40262942",
    "results": "Compared with baseline, the WOMAC and VAS scores in the two groups were significantly decreased at each timepoints(",
    "title": "[The long-term follow-up clinical research of ultrasound-guided warm needle knife in treatment of advanced knee osteoarthritis].",
    "xml": "<Element 'PubmedArticle' at 0x788503b668e0>"
}