{
    "abstract": "This study aimed to investigate the influence of age on postoperative oral function in older adults with oral squamous cell carcinoma and its cutoffs. 102 patients (74 males; 28 females) with oral squamous cell carcinoma were treated according to the National Comprehensive Cancer Network guidelines at the Department of Oral and Maxillofacial Surgery, Shimane University Hospital, between September 2019 and March 2023 were included. Their mean age was 69.6 years. Background data were obtained from the medical records, and oral function measurements were performed the day before discharge. Final analysis was performed using the receiver operating characteristic (ROC) curve and propensity score. The primary tumor site was the tongue in 45 (44.1%), gingiva in 41 (40.2%), and other sites in 16 (15.7%) patients. ROC analysis showed a cutoff age of 75 years for occlusal force. The propensity score method showed that the odds ratio of age was 4.32 (confidence interval: 1.48\u2009-\u200912.55 [P\u2009=\u20090.01]) for occlusal force. Treatment age is independently associated with postoperative oral function, and the incidence of postoperative oral dysfunction is approximately four times higher for patients aged\u2009>\u200975 years. The development of measures for postoperative oral function recovery may be particularly necessary in older adult patients aged\u2009>\u200975 years.",
    "authors": [
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.",
            "firstname": "Tatsuhito",
            "initials": "T",
            "lastname": "Kotani"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.",
            "firstname": "Yuhei",
            "initials": "Y",
            "lastname": "Matsuda"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.",
            "firstname": "Mayu",
            "initials": "M",
            "lastname": "Takeda"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.\nDepartment of Oral and Maxillofacial Surgery, Masuda Red Cross Hospital, 103-1, Otoyoshi-cho, Masuda, Shimane, 698-0003, Japan.",
            "firstname": "Reon",
            "initials": "R",
            "lastname": "Morioka"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.",
            "firstname": "Yukiho",
            "initials": "Y",
            "lastname": "Shimamura"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.",
            "firstname": "Rie",
            "initials": "R",
            "lastname": "Osako-Sonoyama"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.",
            "firstname": "Hiroto",
            "initials": "H",
            "lastname": "Tatsumi"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan.",
            "firstname": "Masako",
            "initials": "M",
            "lastname": "Fujioka-Kobayashi"
        },
        {
            "affiliation": "Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1, Enya-Cho, Izumo, Shimane, 693-8501, Japan. tkanno@med.shimane-u.ac.jp.",
            "firstname": "Takahiro",
            "initials": "T",
            "lastname": "Kanno"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025. The Author(s).",
    "doi": "10.1038/s41598-025-91017-9",
    "journal": "Scientific reports",
    "keywords": [
        "Age",
        "Cutoff",
        "Oral function",
        "Oral squamous cell carcinoma",
        "Postoperative oral dysfunction"
    ],
    "methods": null,
    "publication_date": "2025-03-22",
    "pubmed_id": "40118856\n34971883\n31335117\n34626024\n26027881\n28918183\n2966125\n28219392\n29417723\n38303257\n34436719\n29882364\n34346106\n34314945\n33494830\n32682651\n25634186\n22511687\n35370481\n33390407\n36098000\n21050499\n21209986\n32428306\n37879558\n35045435\n34199065\n31123524\n9630151\n31182743\n37428408\n31572106\n23996155\n30091142\n2642824\n31837276\n25113939",
    "results": null,
    "title": "Effects of age on postoperative oral function in older adults with oral squamous cell carcinoma and its cutoff values: a cross-sectional study.",
    "xml": "<Element 'PubmedArticle' at 0x7885020e10d0>"
}