{
    "abstract": "Introduction Due to the effects of hemorrhoids on physical and mental health, this study aimed to compare the effect of Myrtus communis herbal and anti-hemorrhoid ointments on symptoms of hemorrhoid and quality of life (primary outcomes) and satisfaction of the treatment and side effects (secondary outcomes). Methods This triple-blind randomized controlled trial was performed on women with grade I and II hemorrhoid referring to health centers in Tehran, Iran, in 2017. Individuals were randomly assigned to two groups of 67 people through block randomization method. The intervention group received the Myrtus communis herbal ointment and the control group received anti-hemorrhoid ointment twice a day, every 12\u2009\u00b1\u20092\u2006h, an applicator of the drug through the rectum for 4\u2006weeks. The Colorectal Evaluation of a Clinical Therapeutics Scale (CORECTS) was used to assess the severity of symptoms of hemorrhoid. To assess the quality of life, the World Health Organization Quality of Life questionnaire (WHOQOL-BREF) was used to measure the general quality of life of participants. This questionnaire was completed once before the start of the study, then on the fourth and the eighth week after the start of the intervention. Repeated measure ANOVA, Chi-square, Mann-Whitney U and independent t-test were used for data analysis. Results The severity of all symptoms of hemorrhoid decreased in both two group and there was no statistically significant difference between the two groups (p>0.05). However, the mean of anal itching at 4 and 8\u2006weeks after the intervention was significantly lower in the Myrtus communis ointment group (p<0.05). There was no significant difference between groups in terms of quality of life at 4 and 8\u2006weeks after the intervention (p>0.05). There was a significant difference between the two groups in terms of satisfaction with the drug (p=0.019) and the participants in the Myrtus communis ointment group were more satisfied with their drug use. Conclusions Myrtus communis herbal ointment was able to reduce the symptoms of hemorrhoid in the affected women. Therefore, it is likely that the use of this drug will promote the health of mothers with hemorrhoid.",
    "authors": [
        {
            "affiliation": "Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.",
            "firstname": "Jamileh",
            "initials": "J",
            "lastname": "Malekuti"
        },
        {
            "affiliation": "Reproductive Health, Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.",
            "firstname": "Mojgan",
            "initials": "M",
            "lastname": "Mirghafourvand"
        },
        {
            "affiliation": "Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.",
            "firstname": "Khadijeh",
            "initials": "K",
            "lastname": "Samadi"
        },
        {
            "affiliation": "Fellowship of Obstetrics and Gynecology (Perinatologist), Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.",
            "firstname": "Fatemeh",
            "initials": "F",
            "lastname": "Abbasalizadeh"
        },
        {
            "affiliation": "Pharmacognosy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.",
            "firstname": "Laleh",
            "initials": "L",
            "lastname": "Khodaei"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1515/jcim-2018-0147",
    "journal": "Journal of complementary & integrative medicine",
    "keywords": [
        "Myrtus communis herbal ointment",
        "anti-hemorrhoid ointmen",
        "hemorrhoid",
        "quality of life"
    ],
    "methods": null,
    "publication_date": "2019-08-23",
    "pubmed_id": "31433782",
    "results": null,
    "title": "Comparison of the effect of Myrtus communis herbal and anti-hemorrhoid ointments on the hemorrhoid symptoms and quality of life in postpartum women with grade I and II internal hemorrhoid: A triple-blinded randomized controlled clinical trial.",
    "xml": "<Element 'PubmedArticle' at 0x788505bc6d90>"
}