{
    "abstract": "Polylactic acid (PLA), a biodegradable polymer derived from renewable biological macromolecules such as corn starch and sugarcane, exhibits excellent biocompatibility, biodegradability, non-toxicity, and ease of functionalization, showing great potential in dental medicine applications. However, unmodified PLA has inherent drawbacks, such as poor mechanical ductility, slow degradation, and poor hydrophilicity, which limit its use in this field. This paper briefly introduces the structure and performance advantages of PLA and discusses various modification methods, including chemical and physical modifications. The properties of PLA composites are further elaborated on, with an emphasis on their latest advancements in dental implantation, restoration, orthodontics, maxillofacial surgery, and periodontal disease treatment. An outlook on the development trends of PLA-based composites in oral medicine is also provided, to enhance the role of PLA-based composites in this field and offer patients more treatment options and better outcomes.",
    "authors": [
        {
            "affiliation": "College of Stomatology, Guizhou Medical University, Guiyang 550004, China.",
            "firstname": "Chengxiao",
            "initials": "C",
            "lastname": "Pan"
        },
        {
            "affiliation": "College of Stomatology, Guizhou Medical University, Guiyang 550004, China; Department of Oral and Maxillofacial Surgery, Affiliated Stemmatological Hospital of Guizhou Medical University, Guiyang 550004, China.",
            "firstname": "Qiong",
            "initials": "Q",
            "lastname": "Gao"
        },
        {
            "affiliation": "College of Stomatology, Guizhou Medical University, Guiyang 550004, China; Department of Oral and Maxillofacial Surgery, Affiliated Stemmatological Hospital of Guizhou Medical University, Guiyang 550004, China.",
            "firstname": "Youli",
            "initials": "Y",
            "lastname": "Chen"
        },
        {
            "affiliation": "College of Stomatology, Guizhou Medical University, Guiyang 550004, China; Department of Oral and Maxillofacial Surgery, Affiliated Stemmatological Hospital of Guizhou Medical University, Guiyang 550004, China.",
            "firstname": "Yu",
            "initials": "Y",
            "lastname": "Wang"
        },
        {
            "affiliation": "College of Stomatology, Guizhou Medical University, Guiyang 550004, China; Department of Oral and Maxillofacial Surgery, Affiliated Stemmatological Hospital of Guizhou Medical University, Guiyang 550004, China.",
            "firstname": "Zhenglong",
            "initials": "Z",
            "lastname": "Tang"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2025. Published by Elsevier B.V.",
    "doi": "10.1016/j.ijbiomac.2025.143528",
    "journal": "International journal of biological macromolecules",
    "keywords": [
        "Composites",
        "Current applications",
        "Dental medicine",
        "PLA",
        "Research progress"
    ],
    "methods": null,
    "publication_date": "2025-04-28",
    "pubmed_id": "40288709",
    "results": null,
    "title": "Recent progress in biosourced polylactic acid-based biocomposites for dentistry: A review.",
    "xml": "<Element 'PubmedArticle' at 0x788506f3f510>"
}