{
    "abstract": "Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells with anti-inflammatory activity, and expanded murine MDSCs are capable of attenuating preclinical acute graft-versus-host disease (aGVHD) severity. Two murine cGVHD models were used to evaluate the effectiveness of ex vivo cultured human cord blood (hCB) MDSCs in chronic GVHD (cGVHD). First, GVHD recipients surviving in a classic C57BL/6 into MHC-mismatched BALB/c aGVHD model developed cGVHD. Second, donor pretreatment with granulocyte colony-stimulating factor (G-CSF) induced cGVHD. hCB-MDSCs (1\u202f\u00d7\u202f10",
    "authors": [
        {
            "affiliation": "Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.",
            "firstname": "Ji-Young",
            "initials": "JY",
            "lastname": "Lim"
        },
        {
            "affiliation": "Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.",
            "firstname": "Da-Bin",
            "initials": "DB",
            "lastname": "Ryu"
        },
        {
            "affiliation": "Catholic Hematopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea, Seoul, Korea.",
            "firstname": "Mi-Young",
            "initials": "MY",
            "lastname": "Park"
        },
        {
            "affiliation": "Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.",
            "firstname": "Sung-Eun",
            "initials": "SE",
            "lastname": "Lee"
        },
        {
            "affiliation": "Department of Pathology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.",
            "firstname": "Gyeongsin",
            "initials": "G",
            "lastname": "Park"
        },
        {
            "affiliation": "Catholic Hematopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea, Seoul, Korea.",
            "firstname": "Tai-Gyu",
            "initials": "TG",
            "lastname": "Kim"
        },
        {
            "affiliation": "Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea. Electronic address: ckmin@catholic.ac.kr.",
            "firstname": "Chang-Ki",
            "initials": "CK",
            "lastname": "Min"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2018. Published by Elsevier Inc.",
    "doi": "10.1016/j.bbmt.2018.07.004",
    "journal": "Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation",
    "keywords": [
        "Chronic GVHD",
        "Human umbilical cord blood",
        "Myeloid-derived suppressor cells",
        "Th 17",
        "Thymus"
    ],
    "methods": null,
    "publication_date": "2018-07-15",
    "pubmed_id": "30006304",
    "results": null,
    "title": "Ex Vivo Generated Human Cord Blood Myeloid-Derived Suppressor Cells Attenuate Murine Chronic Graft-versus-Host Diseases.",
    "xml": "<Element 'PubmedArticle' at 0x788506d50680>"
}