{
    "abstract": "Smad Family Member (SMAD), a protein family responsible for transducing the signal induced by TGF-\u03b2 into the nucleus, is thought to play a role in the pathology of many heart diseases. Therefore, we aimed to evaluate the influence of the SMAD1 rs1016792 polymorphism and gene expression on pulmonary arterial hypertension (PAH) due to congenital heart disease (CHD) in children. A total of 90 children, 45 of whom were PAH-CHD children and 45 healthy children, were included in the study. Patients were selected from those who were diagnosed and followed in the Department of Pediatric Cardiology.The ",
    "authors": [
        {
            "affiliation": "Department of Medical Biology, Faculty of Medicine, Mersin University, Mersin, Turkey.",
            "firstname": "Adnan Selim",
            "initials": "AS",
            "lastname": "Kimyon"
        },
        {
            "affiliation": "Department of Medical Biology, Faculty of Medicine, Mersin University, Mersin, Turkey.",
            "firstname": "Ay\u015feg\u00fcl",
            "initials": "A",
            "lastname": "\u00c7etinkaya"
        },
        {
            "affiliation": "Department of Cardiology, Forum Yasam Hospital, Mersin, Turkey.",
            "firstname": "Olgu",
            "initials": "O",
            "lastname": "Hall\u0131o\u011flu K\u0131l\u0131n\u00e7"
        },
        {
            "affiliation": "Department of Medical Biology, Faculty of Medicine, Mersin University, Mersin, Turkey.",
            "firstname": "Nurcan",
            "initials": "N",
            "lastname": "Aras"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1080/15257770.2024.2322109",
    "journal": "Nucleosides, nucleotides & nucleic acids",
    "keywords": [
        "RT-PCR",
        "SMAD1",
        "congenital hearth disease",
        "expression",
        "polymorphism",
        "pulmonary arterial hypertension"
    ],
    "methods": null,
    "publication_date": "2024-02-27",
    "pubmed_id": "38410024",
    "results": null,
    "title": "The evaluation of the SMAD1 rs1016792 polymorphism and gene expression on pulmonary hypertension due to congenital heart disease in children: a preliminary study.",
    "xml": "<Element 'PubmedArticle' at 0x7885049f4810>"
}