{
    "abstract": "We report the case of a 35-year-old patient with a syndrome of persistent M\u00fcllerian ducts (PMDS) of the female type (group A). The diagnosis was made in adulthood during an infertility workup. Clinical examination revealed an empty scrotum, a normal penis and bilateral inguinal cystic masses. The spermogram found azoospermia. Imaging using MRI and tomotensidometry found the presence of an uterus, two fallopian tubes and two inguinal positions of polycystic testes. A surgical management was performed for surgical testicular biopsy. Histological examination then found a cystic formation of multi-celled mesothelial origin, with atrophic testis Sertoli cell involution and without sperm. PMDS is a rare form of pseudo-internal hermaphroditism characterized by the presence in a man of the uterus, fallopian tubes and upper vagina with external male genitalia and virilized characters. About 200 cases are reported in the literature. The diagnosis is often made in children intraoperatively during a cure of testicular ectopia. The karyotype is 46\u00a0XY type. The pathogenesis is related to a deficiency of anti-M\u00fcllerian hormone (AMH) or tissue resistance to its action by receptor abnormalities. The regression of the M\u00fcllerian duct derivatives can give three types of PMDS\u00a0: masculine type, feminine type and a transverse type. Surgical treatment is difficult but necessary because of the risk of infertility and ectopic testicular degeneration.",
    "authors": [
        {
            "affiliation": "Laboratoire d'anatomie et d'organogen\u00e8se, UFR de m\u00e9decine d'Amiens, 3, rue des Louvels, 80036 Amiens cedex 1, France; Service d'urologie-transplantation, CHU Amiens-Picardie, avenue La\u00ebnnec, 80480 Salou\u00ebl, France. Electronic address: viartludovic@gmail.com.",
            "firstname": "L",
            "initials": "L",
            "lastname": "Viart"
        },
        {
            "affiliation": "Laboratoire d'anatomie et d'organogen\u00e8se, UFR de m\u00e9decine d'Amiens, 3, rue des Louvels, 80036 Amiens cedex 1, France.",
            "firstname": "J",
            "initials": "J",
            "lastname": "Peltier"
        },
        {
            "affiliation": "Service d'urologie-transplantation, CHU Amiens-Picardie, avenue La\u00ebnnec, 80480 Salou\u00ebl, France.",
            "firstname": "T",
            "initials": "T",
            "lastname": "Forzini"
        },
        {
            "affiliation": "Laboratoire d'anatomie et d'organogen\u00e8se, UFR de m\u00e9decine d'Amiens, 3, rue des Louvels, 80036 Amiens cedex 1, France.",
            "firstname": "C",
            "initials": "C",
            "lastname": "Page"
        },
        {
            "affiliation": "Laboratoire d'anatomie et d'organogen\u00e8se, UFR de m\u00e9decine d'Amiens, 3, rue des Louvels, 80036 Amiens cedex 1, France.",
            "firstname": "P",
            "initials": "P",
            "lastname": "Foulon"
        },
        {
            "affiliation": "Service d'urologie-transplantation, CHU Amiens-Picardie, avenue La\u00ebnnec, 80480 Salou\u00ebl, France.",
            "firstname": "F",
            "initials": "F",
            "lastname": "Saint"
        },
        {
            "affiliation": "Laboratoire d'anatomie et d'organogen\u00e8se, UFR de m\u00e9decine d'Amiens, 3, rue des Louvels, 80036 Amiens cedex 1, France.",
            "firstname": "E",
            "initials": "E",
            "lastname": "Havet"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2015 Elsevier Masson SAS. All rights reserved.",
    "doi": "10.1016/j.morpho.2015.01.002",
    "journal": "Morphologie : bulletin de l'Association des anatomistes",
    "keywords": [
        "Ectopie testiculaire",
        "Infertility",
        "Infertilit\u00e9",
        "Persistent M\u00fcllerian duct syndrome (PMDS)",
        "Syndrome de persistance des canaux m\u00e9son\u00e9phrotiques de M\u00fcller",
        "Undescended testicles"
    ],
    "methods": null,
    "publication_date": "2015-02-25",
    "pubmed_id": "25708641",
    "results": null,
    "title": "[Persistent M\u00fcllerian ducts syndrome: one case of late hypofertility].",
    "xml": "<Element 'PubmedArticle' at 0x788506bdcf40>"
}