{
    "abstract": "Over the past five years, the pregnancy rate in assisted reproductive technology (ART) programs in Russia has remained relatively stable. The aim of this study was to assess the distribution of monocyte and macrophage subsets in the blood and follicular fluid of infertile women undergoing assisted reproductive technology.\nThe study involved 45 women with a mean age of 35 \u00b1 4.66 years. Monocytes and macrophages were identified using flow cytometry.\nWe observed a decrease in the CD68+CD163+CD206+ and the CD68+CD163-CD206+ cells in patients with a body mass index (BMI) >25 by 0.19 times and 6.56 times, respectively, compared to the group with a BMI <25 (\nA critical component of the inflammatory reaction in patients undergoing ",
    "authors": [
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.",
            "firstname": "Evgeny D",
            "initials": "ED",
            "lastname": "Merkulov"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.",
            "firstname": "Anastasia V",
            "initials": "AV",
            "lastname": "Prozorova"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.",
            "firstname": "Iuliia G",
            "initials": "IG",
            "lastname": "Samoilova"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.\nLaboratory of Tumor Biochemistry, Cancer Research Institute, Tomsk National Research Medical Center, 634009 Tomsk, Russia.",
            "firstname": "Dmitry A",
            "initials": "DA",
            "lastname": "Svarovsky"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.",
            "firstname": "Kira A",
            "initials": "KA",
            "lastname": "Sidorenkova"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.\nLaboratory of Tumor Biochemistry, Cancer Research Institute, Tomsk National Research Medical Center, 634009 Tomsk, Russia.",
            "firstname": "Liudmila V",
            "initials": "LV",
            "lastname": "Spirina"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.\nLaboratory of Tumor Biochemistry, Cancer Research Institute, Tomsk National Research Medical Center, 634009 Tomsk, Russia.",
            "firstname": "Marina N",
            "initials": "MN",
            "lastname": "Stakheeva"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.",
            "firstname": "Oxana S",
            "initials": "OS",
            "lastname": "Timofeeva"
        },
        {
            "affiliation": "Division of Biochemistry and Molecular Biology, Federal State Budgetary Educational Institution of Higher Education \"Siberian State Medical University\" of the Ministry of Health of Russia, 634050 Tomsk, Russia.",
            "firstname": "Ilya A",
            "initials": "IA",
            "lastname": "Petrov"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025 The Author(s). Published by IMR Press.",
    "doi": "10.31083/FBL26660",
    "journal": "Frontiers in bioscience (Landmark edition)",
    "keywords": [
        "assisted reproductive technology",
        "embryo competence",
        "follicular fluid",
        null,
        "macrophages",
        "monocytes",
        "oocytes"
    ],
    "methods": null,
    "publication_date": "2025-01-25",
    "pubmed_id": "39862094",
    "results": "We observed a decrease in the CD68+CD163+CD206+ and the CD68+CD163-CD206+ cells in patients with a body mass index (BMI) >25 by 0.19 times and 6.56 times, respectively, compared to the group with a BMI <25 (",
    "title": "Monocyte and Macrophage in Follicular Liquid: Predictive Markers of Embryo Quality in Women with Obesity and Infertility.",
    "xml": "<Element 'PubmedArticle' at 0x788504e89490>"
}