{
    "abstract": "To compare the efficacy and safety of intravenous and intramuscular oxytocin in preventing atonic primary postpartum haemorrhage in the third stage of labour.\nA double-blind randomised clinical study on consenting women without risk factors for primary postpartum haemorrhage in labour at term. Two hundred and thirty-two women were randomly allotted into intravenous (\nThe baseline socio-demographic and clinical characteristics were similar between the two groups (\nAlthough oxytocin in both study groups showed similar efficacy in terms of preventing atonic primary postpartum haemorrhage, participants who received intravenous oxytocin were more likely to require additional uterotonics to reduce their likelihood of having an atonic primary postpartum haemorrhage. However, both routes have similar side effect profiles.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.",
            "firstname": "Emmanuel Ikechukwu",
            "initials": "EI",
            "lastname": "Okaforcha"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "George Uchenna",
            "initials": "GU",
            "lastname": "Eleje"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Joseph Ifeanyichukwu",
            "initials": "JI",
            "lastname": "Ikechebelu"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Chukwuemeka Okwudili",
            "initials": "CO",
            "lastname": "Ezeama"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Havana Hospital, Lagos, Nigeria.",
            "firstname": "Emeka Philip",
            "initials": "EP",
            "lastname": "Igbodike"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Nigeria.",
            "firstname": "Emmanuel Onyebuchi",
            "initials": "EO",
            "lastname": "Ugwu"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Boniface Chukwuneme",
            "initials": "BC",
            "lastname": "Okpala"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Ikechukwu Innocent",
            "initials": "II",
            "lastname": "Mbachu"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Osita Samuel",
            "initials": "OS",
            "lastname": "Umeononihu"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Chukwudi Anthony",
            "initials": "CA",
            "lastname": "Ogabido"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Daniel Nnaemeka",
            "initials": "DN",
            "lastname": "Onwusulu"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.\nDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Nigeria.",
            "firstname": "Charlotte Blanche",
            "initials": "CB",
            "lastname": "Oguejiofor"
        },
        {
            "affiliation": "Department of Psychiatry, Leicestershire Partnership NHS Trust, Leicester, UK.",
            "firstname": "Chidinma Charity",
            "initials": "CC",
            "lastname": "Okafor"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.",
            "firstname": "Chinedu Lawrence",
            "initials": "CL",
            "lastname": "Olisa"
        },
        {
            "affiliation": "Department of Medical Physiology, College of Medicine and Health Sciences, University of Rwanda, Huye, Rwanda.",
            "firstname": "David Chibuike",
            "initials": "DC",
            "lastname": "Ikwuka"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, ESUT College of Medicine, Parklane, Nigeria.",
            "firstname": "Ifeanyichukwu Jude",
            "initials": "IJ",
            "lastname": "Ofor"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.",
            "firstname": "Chigozie Geoffrey",
            "initials": "CG",
            "lastname": "Okafor"
        }
    ],
    "conclusions": "Although oxytocin in both study groups showed similar efficacy in terms of preventing atonic primary postpartum haemorrhage, participants who received intravenous oxytocin were more likely to require additional uterotonics to reduce their likelihood of having an atonic primary postpartum haemorrhage. However, both routes have similar side effect profiles.",
    "copyrights": "\u00a9 The Author(s) 2024.",
    "doi": "10.1177/20503121241230484",
    "journal": "SAGE open medicine",
    "keywords": [
        "Intravenous route",
        "intramuscular route",
        "oxytocin",
        "primary postpartum haemorrhage",
        "third stage of labour",
        "uterine atony"
    ],
    "methods": null,
    "publication_date": "2024-02-26",
    "pubmed_id": "38406581\n19324236\n23773785\n14608446\n23586122\n22502595\n35297039\n33252891\n22071837\n10908457\n18164304\n22336866\n19603316\n24173606\n15684155\n22336865\n33169839\n9236641\n24365208\n14746950\n20414472\n25108586\n26980230\n20060162\n20060161\n23433172\n30181338\n5311917\n18385263\n26154451",
    "results": "The baseline socio-demographic and clinical characteristics were similar between the two groups (",
    "title": "Intravenous versus intramuscular oxytocin injection for preventing uterine atonic primary postpartum haemorrhage in third stage of labour: A double-blind randomised controlled trial.",
    "xml": "<Element 'PubmedArticle' at 0x788501e43ab0>"
}