{
    "abstract": "Gestational trophoblastic disease (GTD) is a group of diseases associated with pregnancies that demonstrate abnormal development of trophoblastic cells. GTD includes hydatidiform moles (HM) that may continue to further develop into gestational trophoblastic neoplasms (GTN), such as choriocarcinoma (CC). Gestational CC is a malignant mass development that may arise from HM, from other (normal) pregnancies or from other gestational events (such as ectopic pregnancies). The aim of this review is to outline current understating of the genetics and epigenetics of GTD and gestational CC and the link between the two diseases.",
    "authors": [
        {
            "affiliation": "Department of Anatomy, Faculty of Medicine and Surgery University of Malta, Malta; Department of Pathology, Mater Dei Hospital, Malta. Electronic address: graziella.camilleri.09@um.edu.mt.",
            "firstname": "Graziella",
            "initials": "G",
            "lastname": "Camilleri"
        },
        {
            "affiliation": "Department of Anatomy, Faculty of Medicine and Surgery University of Malta, Malta.",
            "firstname": "Jean",
            "initials": "J",
            "lastname": "Calleja-Aguis"
        },
        {
            "affiliation": "Department of Anatomy, Faculty of Medicine and Surgery University of Malta, Malta; Department of Pathology, Mater Dei Hospital, Malta.",
            "firstname": "Edith",
            "initials": "E",
            "lastname": "Said"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.",
    "doi": "10.1016/j.ejso.2024.108727",
    "journal": "European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology",
    "keywords": [
        "Choriocarcinoma",
        "Gestational neoplasms",
        "Gestational trophoblastic disease",
        "Hydatidiform mole",
        "Molar pregnancy"
    ],
    "methods": null,
    "publication_date": "2024-10-07",
    "pubmed_id": "39370364",
    "results": null,
    "title": "Trophoblastic disease and choriocarcinoma.",
    "xml": "<Element 'PubmedArticle' at 0x7885061ab150>"
}