{
    "abstract": "This prospective, longitudinal, pragmatic study describes at home treatment with a proprietary advanced pneumatic compression device (APCD) for patients with lower extremity lymphedema (LED).\nFollowing institutiona review board approval, four participating Veterans Affairs centers enrolled LED patients from 2016 to 2022. The primary outcome measures were health-related quality of life (HR-QoL) questionnaires (lymphedema quality of life-leg and the generic SF-36v2) obtained at baseline and 12, 24, and 52\u00a0weeks. The secondary outcome measures were limb circumference, cellulitis events, skin quality, and compliance with APCD and other compression therapies.\nBecause a portion of the trial was conducted during the coronavirus disease 2019 pandemic, 179 patients had 52 weeks of follow-up, and 143 had complete measurements at all time points. The baseline characteristics were a mean age of 66.9\u00a0\u00b1 10.8\u00a0years, 91% were men, and the mean body mass index was 33.8\u00a0\u00b1 6.9 kg/m\nThis longitudinal study of Veterans Affairs patients with LED demonstrated improved generic and disease-specific HR-QoL through 52\u00a0weeks with at home use of an APCD. Limb girth, cellulitis episodes, and skin discoloration were reduced, with excellent compliance.",
    "authors": [
        {
            "affiliation": "Department of Surgery, VA New Jersey Healthcare System, East Orange, NJ; Division of Vascular Surgery, Rutgers New Jersey Medical School, Newark NJ. Electronic address: padberft@njms.rutgers.edu.",
            "firstname": "Frank T",
            "initials": "FT",
            "lastname": "Padberg"
        },
        {
            "affiliation": "Department of Surgery, VA Maryland Healthcare System, Baltimore, MD; Division of Vascular Surgery, University of Maryland School of Medicine, Baltimore, MD.",
            "firstname": "Areck",
            "initials": "A",
            "lastname": "Ucuzian"
        },
        {
            "affiliation": "Department of Surgery, VA Western NY Healthcare System, Buffalo, NY; Division of Vascular Surgery, Department of Surgery, State University of New York, Buffalo, NY.",
            "firstname": "Hasan",
            "initials": "H",
            "lastname": "Dosluoglu"
        },
        {
            "affiliation": "Department of Surgery, VA New York Harbor Healthcare System, New York, NY; Division of Vascular and Endovascular Surgery, NYU Langone Health, New York, NY; Division of Vascular Surgery, Department of Surgery, NYU Grossman School of Medicine, New York, NY.",
            "firstname": "Glenn",
            "initials": "G",
            "lastname": "Jacobowitz"
        },
        {
            "affiliation": "Department of Surgery, Tufts University School of Medicine, Boston, MA.",
            "firstname": "Thomas F",
            "initials": "TF",
            "lastname": "O'Donnell"
        }
    ],
    "conclusions": null,
    "copyrights": "Published by Elsevier Inc.",
    "doi": "10.1016/j.jvsv.2024.101892",
    "journal": "Journal of vascular surgery. Venous and lymphatic disorders",
    "keywords": [
        "Lymphatic",
        "Lymphedema",
        "Nonoperative management",
        "Phlebolymphedema",
        "Quality of life",
        "Venous Insufficiency"
    ],
    "methods": null,
    "publication_date": "2024-04-19",
    "pubmed_id": "38636734\n32521126\n35258350\n21258451\n18519956\n28214496\n26256706\n31629128\n37073384\n33137494\n25956549\n11124729\n17938389\n31992537\n34688398\n29404923\n23973278\n26444458\n34652229\n24590276\n22768469\n22751255\n22646649\n31798464\n11460821\n12514581\n34343719\n25994425",
    "results": "Because a portion of the trial was conducted during the coronavirus disease 2019 pandemic, 179 patients had 52 weeks of follow-up, and 143 had complete measurements at all time points. The baseline characteristics were a mean age of 66.9\u00a0\u00b1 10.8\u00a0years, 91% were men, and the mean body mass index was 33.8\u00a0\u00b1 6.9 kg/m",
    "title": "Longitudinal assessment of health-related quality of life and clinical outcomes with at home advanced pneumatic compression treatment of lower extremity lymphedema.",
    "xml": "<Element 'PubmedArticle' at 0x78850360f060>"
}