{
    "abstract": "In animal studies it has been observed that the inhibitory neuromodulator adenosine is released into the cerebral interstitial space during hypoxic challenges. Adenosine's actions on the A",
    "authors": [
        {
            "affiliation": "Institute of Neuroscience and Medicine, Molecular Organization of the Brain (INM-2), Forschungszentrum J\u00fclich, J\u00fclich, Germany.",
            "firstname": "Manuel",
            "initials": "M",
            "lastname": "Michno"
        },
        {
            "affiliation": "Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.\nDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Cologne, Cologne, Germany.",
            "firstname": "Jan",
            "initials": "J",
            "lastname": "Schmitz"
        },
        {
            "affiliation": "Institute of Neuroscience and Medicine, Molecular Organization of the Brain (INM-2), Forschungszentrum J\u00fclich, J\u00fclich, Germany.",
            "firstname": "Anna L",
            "initials": "AL",
            "lastname": "Foerges"
        },
        {
            "affiliation": "Institute of Neuroscience and Medicine, Molecular Organization of the Brain (INM-2), Forschungszentrum J\u00fclich, J\u00fclich, Germany.",
            "firstname": "Simone",
            "initials": "S",
            "lastname": "Beer"
        },
        {
            "affiliation": "Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.\nMedical Faculty, University of Cologne, Cologne, Germany.",
            "firstname": "Jens",
            "initials": "J",
            "lastname": "Jordan"
        },
        {
            "affiliation": "Institute of Neuroscience and Medicine, Nuclear Chemistry (INM-5), Forschungszentrum J\u00fclich, J\u00fclich, Germany.",
            "firstname": "Bernd",
            "initials": "B",
            "lastname": "Neumaier"
        },
        {
            "affiliation": "Institute of Neuroscience and Medicine, Molecular Organization of the Brain (INM-2), Forschungszentrum J\u00fclich, J\u00fclich, Germany.\nDepartment of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.\nGerman Center for Neurodegenerative Diseases, Bonn-Cologne, Germany.",
            "firstname": "Alexander",
            "initials": "A",
            "lastname": "Drzezga"
        },
        {
            "affiliation": "Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.\nInstitute of Experimental Epileptology and Cognition Research, University of Bonn Medical Center, Bonn, Germany; and.",
            "firstname": "Daniel",
            "initials": "D",
            "lastname": "Aeschbach"
        },
        {
            "affiliation": "Institute of Neuroscience and Medicine, Molecular Organization of the Brain (INM-2), Forschungszentrum J\u00fclich, J\u00fclich, Germany.",
            "firstname": "Andreas",
            "initials": "A",
            "lastname": "Bauer"
        },
        {
            "affiliation": "Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.",
            "firstname": "Jens",
            "initials": "J",
            "lastname": "Tank"
        },
        {
            "affiliation": "Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.\nDepartment of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.",
            "firstname": "Henning",
            "initials": "H",
            "lastname": "Weis"
        },
        {
            "affiliation": "Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.\nInstitute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.",
            "firstname": "Eva-Maria",
            "initials": "EM",
            "lastname": "Elmenhorst"
        },
        {
            "affiliation": "Institute of Neuroscience and Medicine, Molecular Organization of the Brain (INM-2), Forschungszentrum J\u00fclich, J\u00fclich, Germany; d.elmenhorst@fz-juelich.de.\nDepartment of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.",
            "firstname": "David",
            "initials": "D",
            "lastname": "Elmenhorst"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025 by the Society of Nuclear Medicine and Molecular Imaging.",
    "doi": "10.2967/jnumed.124.268455",
    "journal": "Journal of nuclear medicine : official publication, Society of Nuclear Medicine",
    "keywords": [
        "A1AR",
        "ASL",
        "PET",
        "[18F]CPFPX",
        "adenosine receptors",
        "hypoxia"
    ],
    "methods": null,
    "publication_date": "2024-12-13",
    "pubmed_id": "39667818",
    "results": null,
    "title": "Effect of Acute Hypoxia Exposure on the Availability of A",
    "xml": "<Element 'PubmedArticle' at 0x78850596de40>"
}