{
    "abstract": "Primary aim of this study was to investigate endometriosis characteristics of patients with psychiatric conditions or depression. The secondary aim was to study tolerability of dienogest in this context.\nThis observational case-control study included endometriosis data from patients visiting our clinic from 2015-2021. We collected information from patient charts and in phone interviews based on a structured survey. Patients with surgical confirmed endometriosis were included.\n344 patients fulfilled the inclusion criteria: \nEM-D or EM-P had a higher prevalence of pain symptoms. This could not be attributed to differences in rASRM stage or location of endometriosis lesions. Strong primary dysmenorrhoea might predispose to develop chronic pain-based psychological symptoms. Therefore, early diagnosis and treatment are relevant. Gynaecologist should be aware of the potential impact of dienogest on mood.\nWomen with endometriosis and psychiatric disorders especially have more dyschezia and dyspareunia, independent from rASRM stage, depth of infiltration and localisation of endometriosis lesions. Dienogest has an impact on mood especially in already prone patients.",
    "authors": [
        {
            "affiliation": "Department of Reproductive Endocrinology, University Hospital Zurich, University of Z\u00fcrich, Zurich, Switzerland.",
            "firstname": "Hanna",
            "initials": "H",
            "lastname": "Dietrich"
        },
        {
            "affiliation": "Department of Reproductive Endocrinology, University Hospital Zurich, University of Z\u00fcrich, Zurich, Switzerland.",
            "firstname": "Chiara",
            "initials": "C",
            "lastname": "Knobel"
        },
        {
            "affiliation": "Department of Reproductive Endocrinology, University Hospital Zurich, University of Z\u00fcrich, Zurich, Switzerland.",
            "firstname": "Lea",
            "initials": "L",
            "lastname": "Portmann"
        },
        {
            "affiliation": "Department of Gynaecology, University Hospital Zurich, Zurich, Switzerland.",
            "firstname": "Julian",
            "initials": "J",
            "lastname": "Metzler"
        },
        {
            "affiliation": "Department of Gynaecology, University Hospital Zurich, Zurich, Switzerland.",
            "firstname": "Anne",
            "initials": "A",
            "lastname": "Muendane"
        },
        {
            "affiliation": "Department of Reproductive Endocrinology, University Hospital Zurich, University of Z\u00fcrich, Zurich, Switzerland.",
            "firstname": "Angela",
            "initials": "A",
            "lastname": "Niggli"
        },
        {
            "affiliation": "Department of Neurology, University Hospital Zurich, Zurich, Zurich, Switzerland.",
            "firstname": "Maria S",
            "initials": "MS",
            "lastname": "Neumeier"
        },
        {
            "affiliation": "Department of Gynaecology, University Hospital Zurich, Zurich, Switzerland.",
            "firstname": "Patrick",
            "initials": "P",
            "lastname": "Imesch"
        },
        {
            "affiliation": "Department of Reproductive Endocrinology, University Hospital Zurich, University of Z\u00fcrich, Zurich, Switzerland.",
            "firstname": "Gabriele S",
            "initials": "GS",
            "lastname": "Merki-Feld"
        }
    ],
    "conclusions": "EM-D or EM-P had a higher prevalence of pain symptoms. This could not be attributed to differences in rASRM stage or location of endometriosis lesions. Strong primary dysmenorrhoea might predispose to develop chronic pain-based psychological symptoms. Therefore, early diagnosis and treatment are relevant. Gynaecologist should be aware of the potential impact of dienogest on mood.",
    "copyrights": null,
    "doi": "10.1080/13625187.2023.2199899",
    "journal": "The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception",
    "keywords": [
        "Endometriosis",
        "depression",
        "dyschezia",
        "dysmenorrhoea",
        "dyspareunia",
        "psychiatric disorder"
    ],
    "methods": null,
    "publication_date": "2023-05-03",
    "pubmed_id": "37132337",
    "results": "344 patients fulfilled the inclusion criteria: ",
    "title": "Endometriosis features and dienogest tolerability in women with depression: a case-control study.",
    "xml": "<Element 'PubmedArticle' at 0x78850371b970>"
}