{
    "abstract": "\u2003The impact of type 1 DM (T1DM) on thromboembolism in pregnancy is uncertain. We hypothesized that T1DM is associated with higher rates of thrombotic events during pregnancy and the postpartum period.\n\u2003This is a retrospective cohort study utilizing the National Inpatient Sample database from HCUP/AHRQ for 2017-2019. Pregnant and postpartum patients with a history of T1DM were compared to those without. The primary outcome was a composite diagnosis of any thrombotic disease (pulmonary embolism [PE], deep vein thrombosis [DVT], cerebral vascular thrombosis [CVT], or other thromboses). Secondary outcomes were the diagnosis of each individual type of thromboembolic event. Groups were compared via student's test, chi-squared, and logistic regression analyses, controlling for confounders including age, race, obesity, tobacco use, cHTN, asthma, anemia, and cesarean section.\n\u2003A total of 2,361,711 subjects met the criteria. Patients with T1DM encompassed 0.4% of subjects (\n\u2003T1DM is associated with an increased risk of thromboembolic events in pregnancy.\n\u00b7 T1DM is independently associated with VTE.. \u00b7 PE and DVT are the most common events.. \u00b7 T1DM has an impact on VTE similar to obesity..",
    "authors": [
        {
            "affiliation": "Ascension St. Alexius Department of Obstetrics and Gynecology, Hoffman Estates, Illinois.",
            "firstname": "Jacob",
            "initials": "J",
            "lastname": "Thomas"
        },
        {
            "affiliation": "Ascension St. Alexius Department of Obstetrics and Gynecology, Hoffman Estates, Illinois.",
            "firstname": "Charles",
            "initials": "C",
            "lastname": "Brewerton"
        },
        {
            "affiliation": "Department of Maternal-Fetal Medicine, Advocate Aurora Health, St Oak Lawn, Illinois.",
            "firstname": "Calla",
            "initials": "C",
            "lastname": "Holmgren"
        },
        {
            "affiliation": "Department of Maternal-Fetal Medicine, Advocate Aurora Health, St Oak Lawn, Illinois.",
            "firstname": "Rachel",
            "initials": "R",
            "lastname": "Harrison"
        }
    ],
    "conclusions": "\u2003T1DM is associated with an increased risk of thromboembolic events in pregnancy.",
    "copyrights": "Thieme. All rights reserved.",
    "doi": "10.1055/a-2515-2602",
    "journal": "American journal of perinatology",
    "keywords": [],
    "methods": null,
    "publication_date": "2025-01-15",
    "pubmed_id": "39809448",
    "results": "\u2003A total of 2,361,711 subjects met the criteria. Patients with T1DM encompassed 0.4% of subjects (",
    "title": "Type 1 Diabetes Mellitus and Thromboembolism in Pregnancy.",
    "xml": "<Element 'PubmedArticle' at 0x788504dda390>"
}