{
    "abstract": "Post-operative impairment of gastrointestinal tract function and metabolic consequences occur in patients after gastrectomy by Roux-en-Y method. Short-chain fatty acids and silicon dioxide may prove beneficial in the treatment of these conditions.\nTo evaluate a preparation containing propionic acid and silicon dioxide on the body weight, number of stools and their consistency (the Bristol scale), and pain and a feeling of gastric fullness after a meal, in patients after gastrectomy by Roux-en-Y method.\nMeasurements were performed at the beginning of the study, on day 7 and 14 of application (Colostop\nInitially the average daily number of movements was 10/day, after the therapy it was 3.8/day. At the beginning of the study, 3 patients described their faeces as type 6 and two as type 7 on the Bristol scale. After supplementation, 3 patients described stool consistency as type 5, and two as type 4. Initially, patients rated their pain at 3.4/10 on average, the stomach fullness as 4.6/10. At the end of the study, 3 patients did not feel any pain, while others reported pain at 1/10. Four patients described their feeling of gastric fullness as 1/10, and 1 no longer observed this feeling. Patients disclaimed any adverse effects, and satisfaction after therapy reached 9-10/10 points. Patients' body weight did not change significantly. An improvement in standard diet tolerance was observed. Despite the limited study group, clinical benefits of the supplementation were observed.",
    "authors": [
        {
            "affiliation": "Department of General, Endocrine Surgery and Gastroenterological Oncology, Poznan University of Medical Science, Poznan, Poland.",
            "firstname": "Dorota",
            "initials": "D",
            "lastname": "Domagalska"
        },
        {
            "affiliation": "Department of General, Endocrine Surgery and Gastroenterological Oncology, Poznan University of Medical Science, Poznan, Poland.",
            "firstname": "Bartosz",
            "initials": "B",
            "lastname": "Grzechulski"
        },
        {
            "affiliation": "Department of General, Endocrine Surgery and Gastroenterological Oncology, Poznan University of Medical Science, Poznan, Poland.",
            "firstname": "Jacek",
            "initials": "J",
            "lastname": "Paszkowski"
        },
        {
            "affiliation": "Institute of Microecology, Poznan, Poland.",
            "firstname": "Miros\u0142awa",
            "initials": "M",
            "lastname": "Ga\u0142\u0119cka"
        },
        {
            "affiliation": "Department of General, Endocrine Surgery and Gastroenterological Oncology, Poznan University of Medical Science, Poznan, Poland.",
            "firstname": "Tomasz",
            "initials": "T",
            "lastname": "Banasiewicz"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2020 Termedia.",
    "doi": "10.5114/pg.2020.99040",
    "journal": "Przeglad gastroenterologiczny",
    "keywords": [
        "diarrhea",
        "gastrectomy",
        "propionate",
        "silicon dioxide",
        "surgery"
    ],
    "methods": null,
    "publication_date": "2020-10-03",
    "pubmed_id": "33005272\n3964759\n23460248\n12657389\n27749997\n25396003\n26963409\n27448578\n11427691\n19379128\n28325187\n21831780\n26963409\n32129694",
    "results": null,
    "title": "Postoperative supplementation of propionate and silicon dioxide in patients after total gastrectomy - preliminary report.",
    "xml": "<Element 'PubmedArticle' at 0x788506100950>"
}