{
    "abstract": "To analyze the status of insulin resistance and hyperlipidemia in the regulation of menstrual cycle in patients undergoing sleeve gastrectomy (LSG).\nRetrospective analysis of a typical metabolic syndrome population: 65 cases of sexually mature women underwent weight reduction surgery from January 2015 to June 2018, and for 35 of these cases we collected all clinical data including age, menstrual status, body mass index (BMI), waist-to-hip ratio (WHR), blood lipid level, homeostasis model assessment in insulin resistance (HOMA-IR) and free androgen index (FAI). Sixteen of these patients had menstrual disorder that was characterized by oligomenorrhea and their menstrual cycle was >2 months or <24 days before operation, while their menstrual cycle recovered approximately 1 month to one year after sleeve gastrectomy.\nThe age of our 35 patients with metabolic syndrome was 15-40 years; 19 cases were in the menstrual regularity group and 16 cases in the menstrual disorder group. On analysis of metabolic factors in the two groups, only BMI and FAI distribution in the two groups were statistically different, while lipid levels and insulin resistance levels for abnormal menstrual cycle were not statistically significant. The analysis of blood lipid components showed that high triglyceride levels and high cholesterol levels increased the occurrence of menstrual disorders.\nBMI can be used as one of the important metabolic indicators of menstrual disorders in patients with metabolic syndrome. Excess androgen can increase the occurrence of menstrual disorders, leading to polycystic ovarian syndrome (PCOS). Although insulin resistance is universal in patients with metabolic syndrome, it is not a specific factor that affects menstrual cycle. Hyperlipidemia, especially triglyceride composition, may be one of the driving factors of menstrual disorder.",
    "authors": [
        {
            "affiliation": "Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, People's Republic of China.",
            "firstname": "Yu",
            "initials": "Y",
            "lastname": "Ran"
        },
        {
            "affiliation": "Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, People's Republic of China.",
            "firstname": "Qiang",
            "initials": "Q",
            "lastname": "Yi"
        },
        {
            "affiliation": "Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing City, People's Republic of China.",
            "firstname": "Cong",
            "initials": "C",
            "lastname": "Li"
        }
    ],
    "conclusions": "BMI can be used as one of the important metabolic indicators of menstrual disorders in patients with metabolic syndrome. Excess androgen can increase the occurrence of menstrual disorders, leading to polycystic ovarian syndrome (PCOS). Although insulin resistance is universal in patients with metabolic syndrome, it is not a specific factor that affects menstrual cycle. Hyperlipidemia, especially triglyceride composition, may be one of the driving factors of menstrual disorder.",
    "copyrights": "\u00a9 2020 Ran et al.",
    "doi": "10.2147/DMSO.S285114\n10.1089/jwh.2019.7947\n10.1177/000313481908500327\n10.1515/hmbci-2018-0002\n10.1016/j.bpobgyn.2016.01.006\n10.1016/j.dsx.2019.06.008\n10.1016/j.rbmo.2019.06.014\n10.1016/j.dsx.2019.01.002\n10.4103/ijem.IJEM_305_19\n10.1111/cen.13477\n10.15171/jcvtr.2018.10\n10.1515/jpem-2020-0019\n10.1007/s00404-015-3964-y",
    "journal": "Diabetes, metabolic syndrome and obesity : targets and therapy",
    "keywords": [
        "hyperlipidemia",
        "menstrual cycle",
        "metabolic syndrome",
        "sleeve gastrectomy"
    ],
    "methods": null,
    "publication_date": "2020-12-10",
    "pubmed_id": "33293844\n32077783\n30947769\n29596052\n26972165\n31405703\n31444050\n31336510\n32699789\n28930378\n30116503\n30059968\n32623380\n26615602",
    "results": "The age of our 35 patients with metabolic syndrome was 15-40 years; 19 cases were in the menstrual regularity group and 16 cases in the menstrual disorder group. On analysis of metabolic factors in the two groups, only BMI and FAI distribution in the two groups were statistically different, while lipid levels and insulin resistance levels for abnormal menstrual cycle were not statistically significant. The analysis of blood lipid components showed that high triglyceride levels and high cholesterol levels increased the occurrence of menstrual disorders.",
    "title": "Correlation Between Recovery of Menstrual Cycle and Improvement of Glucose and Lipid Metabolism in Patients with Sleeve Gastrectomy in a Small Chinese Cohort Sample.",
    "xml": "<Element 'PubmedArticle' at 0x788504893d80>"
}