{
    "abstract": "While increased risk of psychiatric burden in patients with polycystic ovarian syndrome (PCOS) is reported in the literature, there is dearth of reports from Saudi Arabia on occurrence of psychological burden in women with PCOS. This study aimed to compare the sociodemographic and clinical features of PCOS cases with non-PCOS control and explore the prevalence of depression, anxiety and stress in PCOS and non-PCOS women.\nThis is a case-control study carried out in PSMMC, Riyadh, Saudi Arabia from March 2019 to June 2019. Samples were recruited by convenience sampling and simple random method in PCOS cases (82) and control group (85), respectively. Depression, Anxiety and Stress Scale-21 (DASS-21) was used to measure the presence of psychological burden.\nHigh percentage of participants were in an age group of 26-35 years (51%) and university educated (64%). Significantly (P\u00a0=\u00a00.001) high proportion of PCOS cases found with irregular menses, hirsutism, infertility and presence of acne (P\u00a0=\u00a00.001) when compared to control group. The odds of developing depression (P\u00a0=\u00a00.006), anxiety (P\u00a0=\u00a00.028) and stress (P\u00a0=\u00a00.000) was significantly higher in PCOS cases compared to control participants. Further, among the three parameters, the occurrence of stress (odds ratio, OR=10.45) in women with PCOS was more common than depression (OR=2.675) and anxiety (OR=2.056).\nRecall bias and inclusion of only one hospital.\nIn conclusion, most of the PCOS cases had stress, depression and anxiety compared to control group. Meeting the psychological need of the PCOS women will help in improving their quality of life.",
    "authors": [
        {
            "affiliation": "Department of Pharmacology and Therapeutics, College of Pharmacy, Al Maarefa University, Dariyah, Riyadh 11597, Saudi Arabia. Electronic address: sasdag@mcst.edu.sa.",
            "firstname": "Syed Mohammed Basheeruddin",
            "initials": "SMB",
            "lastname": "Asdaq"
        },
        {
            "affiliation": "College of Applied Sciences, Al Maarefa University, Riyadh, Saudi Arabia.",
            "firstname": "Farhana",
            "initials": "F",
            "lastname": "Yasmin"
        }
    ],
    "conclusions": "In conclusion, most of the PCOS cases had stress, depression and anxiety compared to control group. Meeting the psychological need of the PCOS women will help in improving their quality of life.",
    "copyrights": "Copyright \u00a9 2020 Elsevier B.V. All rights reserved.",
    "doi": "10.1016/j.jad.2020.05.086",
    "journal": "Journal of affective disorders",
    "keywords": [
        "Anxiety",
        "Depression",
        "Hirsutism",
        "Infertility",
        "Oligomenorrhea",
        "Polycystic ovary syndrome",
        "Stress"
    ],
    "methods": null,
    "publication_date": "2020-05-30",
    "pubmed_id": "32469805",
    "results": "High percentage of participants were in an age group of 26-35 years (51%) and university educated (64%). Significantly (P\u00a0=\u00a00.001) high proportion of PCOS cases found with irregular menses, hirsutism, infertility and presence of acne (P\u00a0=\u00a00.001) when compared to control group. The odds of developing depression (P\u00a0=\u00a00.006), anxiety (P\u00a0=\u00a00.028) and stress (P\u00a0=\u00a00.000) was significantly higher in PCOS cases compared to control participants. Further, among the three parameters, the occurrence of stress (odds ratio, OR=10.45) in women with PCOS was more common than depression (OR=2.675) and anxiety (OR=2.056).",
    "title": "Risk of psychological burden in polycystic ovary syndrome: A case control study in Riyadh, Saudi Arabia.",
    "xml": "<Element 'PubmedArticle' at 0x788503136ac0>"
}