{
    "abstract": "To evaluate the association between neuromuscular blockade agent (NMBA) use and outcome in dogs undergoing mechanical ventilation (MV), including survival to discharge, and complications.\nThe medical records for 227 mechanically ventilated dogs were reviewed for NMBA use, parameters of respiratory status (PaO\nThe NMBA and non-NMBA groups included 28 and 199 dogs, respectively. The median partial pressures of oxygen in arterial blood (PaO\nThis study revealed no statistical significance between NMBA use and survival or complications. However, dogs in the NMBA group likely had more severe hypoxemia than the non-NMBA group, as indicated by their lower PF ratios and SPO",
    "authors": [
        {
            "affiliation": "Department of Critical Care, VCA West Los Angeles, Los Angeles, CA, United States.",
            "firstname": "Lena",
            "initials": "L",
            "lastname": "Ngo"
        },
        {
            "affiliation": "Department of Critical Care, VCA West Los Angeles, Los Angeles, CA, United States.\nDepartment of Veterinary Clinical Sciences, Iowa State University, Ames, IA, United States.",
            "firstname": "Rebecca",
            "initials": "R",
            "lastname": "Walton"
        },
        {
            "affiliation": "Department of Small Animal Clinical Practice, University of Florida, Gainesville, FL, United States.",
            "firstname": "Jacob",
            "initials": "J",
            "lastname": "Wolf"
        },
        {
            "affiliation": "Department of Small Animal Clinical Sciences, Michigan State University, East Lansing, MI, United States.",
            "firstname": "Nyssa",
            "initials": "N",
            "lastname": "Levy"
        },
        {
            "affiliation": "Department of Veterinary Clinical Sciences, University of Minnesota, St. Paul, MN, United States.",
            "firstname": "Tasia",
            "initials": "T",
            "lastname": "Ludwik"
        },
        {
            "affiliation": "College of Veterinary Medicine, University of Georgia, Athens, GA, United States.",
            "firstname": "Britt",
            "initials": "B",
            "lastname": "Thevelein"
        },
        {
            "affiliation": "Department of Veterinary Clinical Sciences, Iowa State University, Ames, IA, United States.",
            "firstname": "April",
            "initials": "A",
            "lastname": "Blong"
        },
        {
            "affiliation": "Precision One Health Initiative, The University of Georgia, Athens, GA, United States.",
            "firstname": "Jiazhang",
            "initials": "J",
            "lastname": "Cai"
        },
        {
            "affiliation": "Precision One Health Initiative, The University of Georgia, Athens, GA, United States.",
            "firstname": "Jonathan",
            "initials": "J",
            "lastname": "Mochel"
        }
    ],
    "conclusions": "This study revealed no statistical significance between NMBA use and survival or complications. However, dogs in the NMBA group likely had more severe hypoxemia than the non-NMBA group, as indicated by their lower PF ratios and SPO",
    "copyrights": "Copyright \u00a9 2025 Ngo, Walton, Wolf, Levy, Ludwik, Thevelein, Blong, Cai and Mochel.",
    "doi": "10.3389/fvets.2025.1539138\n10.2215/CJN.13091021\n10.1177/03000605221128148\n10.1097/CCM.0000000000002027\n10.5152/TJAR.2019.33269\n10.1016/j.jcrc.2018.10.019\n10.1097/01.CCM.0000239435.87433.0D\n10.1056/NEJMoa1005372\n10.1007/s00134-020-06297-8\n10.1111/j.1399-6576.2007.01292.x\n10.1677/joe.0.1800439\n10.1056/NEJM199208203270804\n10.1111/vec.12989\n10.1002/vrc2.59\n10.1002/vrc2.101\n10.1056/NEJMoa1901686\n10.1055/s-0040-1708557\n10.1016/S0195-5616(92)50630-1\n10.1111/vec.13176\n10.1007/s00134-016-4423-3",
    "journal": "Frontiers in veterinary science",
    "keywords": [
        "acute respiratory distress",
        "hypoventilation",
        "hypoxemia",
        "neuromuscular blockade",
        "ventilator complications",
        "ventilator discontinuation"
    ],
    "methods": null,
    "publication_date": "2025-03-20",
    "pubmed_id": "40110427\n35273008\n36173012\n27755068\n31380507\n30396789\n16932229\n20843245\n33159530\n17567267\n15012598\n1353252\n32780507\n31112383\n32685248\n1585571\n35043547\n27342819",
    "results": "The NMBA and non-NMBA groups included 28 and 199 dogs, respectively. The median partial pressures of oxygen in arterial blood (PaO",
    "title": "The association between non-depolarizing neuromuscular blockade agents and survival to discharge in dogs undergoing mechanical ventilation: a multi-center retrospective study of 227 dogs (2010-2020).",
    "xml": "<Element 'PubmedArticle' at 0x788504476bb0>"
}