{
    "abstract": "A wireless implantable interstitial fluid pressure (IFP) sensor with an integrated Guyton chamber is presented. This implantable device enables noninvasive and continuous measurements of IFP. The Guyton chamber allows for an accurate measurement of IFP without the interference from various cellular/tissue components. The sensor consists of a coil, an air chamber, a silicone membrane embedded with a nickel plate, and a Guyton chamber. The fabricated device is 3\u00a0mm in diameter and 1\u00a0mm in thickness. The sensor shows a linear response to the pressure with a sensitivity of 60\u00a0kHz/mmHg and a resolution of 1 mmHg. Experiments in human prostate cancer tumors grown in mice confirm the sensor's capability to operate in vivo and provide continuous wireless measurement of IFP, a surrogate parameter indicating the \"window of opportunity\" for delivering chemo- and radio-therapeutic agents.",
    "authors": [
        {
            "affiliation": null,
            "firstname": "Seung Hyun",
            "initials": "SH",
            "lastname": "Song"
        },
        {
            "affiliation": null,
            "firstname": "Albert",
            "initials": "A",
            "lastname": "Kim"
        },
        {
            "affiliation": null,
            "firstname": "Marcus",
            "initials": "M",
            "lastname": "Brown"
        },
        {
            "affiliation": null,
            "firstname": "Chaeyong",
            "initials": "C",
            "lastname": "Jung"
        },
        {
            "affiliation": null,
            "firstname": "S",
            "initials": "S",
            "lastname": "Ko"
        },
        {
            "affiliation": null,
            "firstname": "Babak",
            "initials": "B",
            "lastname": "Ziaie"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1109/TBME.2016.2522460",
    "journal": "IEEE transactions on bio-medical engineering",
    "keywords": [],
    "methods": null,
    "publication_date": "2016-10-25",
    "pubmed_id": "26829773",
    "results": null,
    "title": "An Implantable Wireless Interstitial Pressure Sensor With Integrated Guyton Chamber: in vivo Study in Solid Tumors.",
    "xml": "<Element 'PubmedArticle' at 0x7885024ce610>"
}