{
    "abstract": "Aortic root thrombosis (ART) is a rare but serious complication following the placement of continuous-flow left ventricular assist devices (CF-LVAD). We present the case of a patient with idiopathic non-ischaemic cardiomyopathy who developed a non-ST elevation myocardial infarction (NSTEMI) secondary to ART after CF-LVAD placement. The patient was treated conservatively with antiplatelet therapy and increased international normalized ratio (INR) goal with resolution of thrombus on repeat imaging. ART may be an under-recognised complication in patients with CF-LVAD. Stasis of blood at the aortic root in patients with CF-LVAD may contribute to the development of ART. Management of these patients presenting with myocardial infarction should be individualised by using a multidisciplinary team approach. Our case report suggests conservative management of NSTEMI secondary to ART in patients with CF-LVAD with antiplatelet therapy and an increased INR goal as a reasonable treatment approach.",
    "authors": [
        {
            "affiliation": "Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, USA.",
            "firstname": "Daniel",
            "initials": "D",
            "lastname": "Holtz"
        },
        {
            "affiliation": "Cardiology, The University of Kansas Medical Center, Kansas City, Kansas, USA.",
            "firstname": "Rhythm",
            "initials": "R",
            "lastname": "Vasudeva"
        },
        {
            "affiliation": "Cardiovascular and Thoracic Surgery, The University of Kansas Medical Center, Kansas City, Kansas, USA.",
            "firstname": "Tyler",
            "initials": "T",
            "lastname": "Zorn"
        },
        {
            "affiliation": "Cardiology, The University of Kansas Medical Center, Kansas City, Kansas, USA.",
            "firstname": "Zubair",
            "initials": "Z",
            "lastname": "Shah"
        },
        {
            "affiliation": "Cardiology, The University of Kansas Medical Center, Kansas City, Kansas, USA tdalia2@kumc.edu.",
            "firstname": "Tarun",
            "initials": "T",
            "lastname": "Dalia"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 BMJ Publishing Group Limited 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.",
    "doi": "10.1136/bcr-2024-264624\n10.1056/NEJMoa1900486\n10.1016/j.healun.2023.08.023\n10.1016/j.jccase.2023.06.011\n10.1016/j.athoracsur.2020.12.038\n10.1016/j.healun.2013.10.021\n10.1007/s10047-014-0758-0\n10.1007/s10047-022-01339-y\n10.1111/echo.13425\n10.1177/02676591221096228\n10.1016/j.healun.2022.01.1197\n10.1016/j.cardfail.2019.01.012",
    "journal": "BMJ case reports",
    "keywords": [
        "Cardiothoracic surgery",
        "Cardiovascular system",
        "Heart failure",
        "Radiology (diagnostics)",
        "Thrombosis"
    ],
    "methods": null,
    "publication_date": "2025-03-29",
    "pubmed_id": "40154551\n30883052\n37739242\n38024109\n16392208\n33465365\n24418737\n24509915\n35604615\n28191682\n35442104\n31271866\n40154551",
    "results": null,
    "title": "Non-ST elevation myocardial infarction from aortic root thrombus after LVAD placement.",
    "xml": "<Element 'PubmedArticle' at 0x788505c60bd0>"
}