{
    "abstract": "The thiazole heterocycle is one of the most common moieties found in various drugs. Using 2-aminothiazole as the core structure, the amino group was functionalized with an amide. As a result, 30 trisubstituted 2-amino-4, 5-diarylthiazole derivatives were synthesized, with different substitutions introduced at the C2, C4, and C5 positions. The anti-",
    "authors": [
        {
            "affiliation": "Yangling Vocational & Technical College, Yangling 712100, China.",
            "firstname": "Dongmei",
            "initials": "D",
            "lastname": "Gao"
        },
        {
            "affiliation": "School of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.",
            "firstname": "Lele",
            "initials": "L",
            "lastname": "Shi"
        },
        {
            "affiliation": "School of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.",
            "firstname": "Yuhang",
            "initials": "Y",
            "lastname": "Huang"
        },
        {
            "affiliation": "School of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.",
            "firstname": "Yingmei",
            "initials": "Y",
            "lastname": "Lv"
        },
        {
            "affiliation": "School of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.",
            "firstname": "Xuan",
            "initials": "X",
            "lastname": "Yang"
        },
        {
            "affiliation": "School of Chemistry and Pharmacy, Northwest A & F University, Yangling 712100, China.",
            "firstname": "Zhenting",
            "initials": "Z",
            "lastname": "Du"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.3390/molecules30071643",
    "journal": "Molecules (Basel, Switzerland)",
    "keywords": [
        "2-Amino-4, 5-diarylthiazole",
        "anti-Candida albicans activity",
        "molecular docking"
    ],
    "methods": null,
    "publication_date": "2025-04-26",
    "pubmed_id": "40286249",
    "results": null,
    "title": "Synthesis of 2-Amino-4, 5-Diarylthiazole Derivatives and Evaluation of Their Anti-",
    "xml": "<Element 'PubmedArticle' at 0x788506f5bc40>"
}