{
    "abstract": "Extracorporeal membrane oxygenation (ECMO) is often used in acute respiratory distress syndrome (ARDS) with refractory hypoxemia. There is limited literature highlighting the development of right ventricular (RV) failure while on ECMO. We conducted a retrospective multicenter observational study including 70 patients who were placed on veno-venous (VV)-ECMO for respiratory failure at Mayo Clinic, Jacksonville, and Mayo Clinic, Rochester, between January 2018 and June 2022 and had at least two post-ECMO transthoracic echoes. The primary outcomes were the incidence and progression of RV dysfunction and dilatation. The secondary outcome was in-patient mortality. Among 70 patients in our cohort, 60.6% had a normal RV function at the time of ECMO placement, whereas only 42% had a normal RV function at the second post-ECMO echo. On multinomial regression, a moderate decrease in RV function was associated with ECMO flow (odds ratio [OR] = 2.32, p = 0.001) and ECMO duration (OR = 1.01, p = 0.01). A moderately dilated RV size was also associated with ECMO flow (OR = 2.62, p < 0.001) and ECMO duration (OR = 1.02, p = 0.02). An increasing degree of RV dysfunction was associated with worse outcomes. Our study showed that the increasing duration and flow of VV-ECMO correlated with progressive RV dilatation and dysfunction, which were associated with poor survival.",
    "authors": [
        {
            "affiliation": "From the Department of Internal Medicine, Ascension Saint Joseph Hospital, Chicago, Illinois.",
            "firstname": "Shahin",
            "initials": "S",
            "lastname": "Isha"
        },
        {
            "affiliation": "Department of Internal Medicine, Mercy Fitzgerald Hospital, Philadelphia, Pennsylvania.",
            "firstname": "Sai Abhishek",
            "initials": "SA",
            "lastname": "Narra"
        },
        {
            "affiliation": "Department of Internal Medicine, Mercy Fitzgerald Hospital, Philadelphia, Pennsylvania.",
            "firstname": "Humera",
            "initials": "H",
            "lastname": "Batool"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Sadhana",
            "initials": "S",
            "lastname": "Jonna"
        },
        {
            "affiliation": "Department of Internal Medicine, Fairview Hospital, Cleveland, Ohio.",
            "firstname": "Abhishek",
            "initials": "A",
            "lastname": "Giri"
        },
        {
            "affiliation": "Cope Lab, Department of Biomedical Engineering, Georgia Institute of Technology,, Atlanta, Georgia.",
            "firstname": "Olivia",
            "initials": "O",
            "lastname": "Herrmann"
        },
        {
            "affiliation": "Florida State College, Jacksonville, Florida.",
            "firstname": "Amari",
            "initials": "A",
            "lastname": "Dyson"
        },
        {
            "affiliation": "Department of Nursing, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Mick D",
            "initials": "MD",
            "lastname": "Nichols"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Rachel",
            "initials": "R",
            "lastname": "Hannon"
        },
        {
            "affiliation": "Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Si",
            "initials": "S",
            "lastname": "Pham"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Pablo",
            "initials": "P",
            "lastname": "Moreno Franco"
        },
        {
            "affiliation": "Department of Transplant, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Maher",
            "initials": "M",
            "lastname": "Baz"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Devang",
            "initials": "D",
            "lastname": "Sanghavi"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Sean",
            "initials": "S",
            "lastname": "Kiley"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Nathan",
            "initials": "N",
            "lastname": "Waldron"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Govind",
            "initials": "G",
            "lastname": "Pandompatam"
        },
        {
            "affiliation": "Department of Anesthesia, Mayo Clinic, Rochester, Minnesota.",
            "firstname": "J Kyle K",
            "initials": "JKK",
            "lastname": "Bohman"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Sanjay",
            "initials": "S",
            "lastname": "Chaudhary"
        },
        {
            "affiliation": "Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.",
            "firstname": "Drew N",
            "initials": "DN",
            "lastname": "Rosenbaum"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Pramod K",
            "initials": "PK",
            "lastname": "Guru"
        },
        {
            "affiliation": "Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.",
            "firstname": "Anirban",
            "initials": "A",
            "lastname": "Bhattacharyya"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 ASAIO 2024.",
    "doi": "10.1097/MAT.0000000000002235",
    "journal": "ASAIO journal (American Society for Artificial Internal Organs : 1992)",
    "keywords": [],
    "methods": null,
    "publication_date": "2024-05-31",
    "pubmed_id": "38819317",
    "results": null,
    "title": "Assessing Right Ventricle Over Time in Patients on Veno-Venous Extracorporeal Membrane Oxygenation: Insights From Serial Echocardiography.",
    "xml": "<Element 'PubmedArticle' at 0x7885030e85e0>"
}