{
    "abstract": "Type 1 von Willebrand disease (VWD) is the most common subtype of VWD, comprising 75% of VWD patients. We provide a systematic review of type 1 VWD in pregnancy. Our objective was to evaluate the rate of postpartum hemorrhage (PPH) in patients with known type 1 VWD. The primary outcome was rate of PPH. Primary PPH was defined as a cumulative blood loss \u22651,000\u2009mL, or blood loss accompanied by signs and symptoms of hypovolemia within 24\u2009hours postpartum or requiring blood products. Secondary PPH was defined as significant bleeding 24\u2009hours to 12 weeks postpartum. Relevant articles published in English pertaining to VWD and pregnancy were identified without any time or study limitations. Seven articles (",
    "authors": [
        {
            "affiliation": "Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania.",
            "firstname": "Rebecca A M",
            "initials": "RAM",
            "lastname": "Pierce-Williams"
        },
        {
            "affiliation": "Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania.\nDepartment of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York.",
            "firstname": "Mona M",
            "initials": "MM",
            "lastname": "Makhamreh"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, South Shore University Hospital, Bay Shore, New York.",
            "firstname": "Sophia",
            "initials": "S",
            "lastname": "Blakey-Cheung"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania.",
            "firstname": "Zimeng",
            "initials": "Z",
            "lastname": "Gao"
        },
        {
            "affiliation": "Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania.",
            "firstname": "Huda B",
            "initials": "HB",
            "lastname": "Al-Kouatly"
        }
    ],
    "conclusions": null,
    "copyrights": "Thieme. All rights reserved.",
    "doi": "10.1055/s-0041-1736572",
    "journal": "Seminars in thrombosis and hemostasis",
    "keywords": [],
    "methods": null,
    "publication_date": "2021-11-09",
    "pubmed_id": "34749402",
    "results": null,
    "title": "Postpartum Hemorrhage in Patients with Type 1 von Willebrand Disease: A Systematic Review.",
    "xml": "<Element 'PubmedArticle' at 0x7885025478d0>"
}