{
    "abstract": "Patients undergoing transcatheter aortic valve implantation (TAVI) are at increased risk of rehospitalization in the early period after discharge from TAVI. The HOSPITAVI study aimed to compare the impact of a standard versus intensified outpatient follow-up on rehospitalization rates within 90 days after TAVI discharge. Patients were 1:1 randomized to either a standard or intensified outpatient follow-up after TAVI discharge. The primary endpoint was the 90-day hospital rehospitalization rate. In total, 300 patients were included: 150 patients were randomized to standard follow-up and 150 patients to intensified outpatient follow-up. The study population had a median age of 79 years, a median EuroSCORE II of 2.9%, and 72% were discharged the day after TAVI. Within 90 days after discharge, the mean number of all-cause hospital readmissions per patient was 0.44 versus 0.35 (HR 0.8 [95% CI, 0.6-1.2], p = 0.23) in the standard versus intensified group, respectively. The mean number of cardiovascular (CV) readmissions per patient was 0.27 versus 0.15 (HR 0.6 [95% CI, 0.4-1.0], p = 0.04) in the standard versus intensified group, respectively. This resulted in a mean number of CV readmission days per patient of 1.52 days versus 0.49 days within the first 90 days in the standard versus intensified group, respectively (p < 0.05). Following TAVI discharge, there was no significant difference in all-cause rehospitalization rates using a standard versus intensified outpatient follow-up approach. However, an intensified outpatient follow-up reduces the burden of early CV rehospitalization after TAVI discharge. (Rehospitalization after transcatheter aortic valve implantation [HOSPITAVI]; NCT05670041).",
    "authors": [
        {
            "affiliation": "The Heart Center, Rigshospitalet, Copenhagen, Denmark. Electronic address: pernille.steen.baekke.02@regionh.dk.",
            "firstname": "Pernille Steen",
            "initials": "PS",
            "lastname": "B\u00e6kke"
        },
        {
            "affiliation": "The Heart Center, Rigshospitalet, Copenhagen, Denmark.",
            "firstname": "Troels H\u00f8jsgaard",
            "initials": "TH",
            "lastname": "J\u00f8rgensen"
        },
        {
            "affiliation": "The Heart Center, Rigshospitalet, Copenhagen, Denmark.",
            "firstname": "Gintautas",
            "initials": "G",
            "lastname": "Bieliauskas"
        },
        {
            "affiliation": "Abbott, Santa Clara, California.",
            "firstname": "Lars",
            "initials": "L",
            "lastname": "Sondergaard"
        },
        {
            "affiliation": "The Heart Center, Rigshospitalet, Copenhagen, Denmark.",
            "firstname": "Ole",
            "initials": "O",
            "lastname": "De Backer"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2025 The Author(s). Published by Elsevier Inc. All rights reserved.",
    "doi": "10.1016/j.amjcard.2025.01.031",
    "journal": "The American journal of cardiology",
    "keywords": [
        "aortic valve stenosis",
        "intensified follow-up",
        "outpatient follow-up",
        "patient care",
        "readmission",
        "rehospitalization",
        "transcatheter aortic valve implantation"
    ],
    "methods": null,
    "publication_date": "2025-02-04",
    "pubmed_id": "39900323",
    "results": null,
    "title": "Impact of Intensified Outpatient Follow-Up on Rehospitalization After Transcatheter Aortic Valve Implantation: Results From the HOSPITAVI Trial.",
    "xml": "<Element 'PubmedArticle' at 0x78850369db20>"
}