{
    "abstract": "This case report aimed to summarize the risk factors, clinical characteristics, imaging changes, and maternal and fetal prognosis associated with Moyamoya disease in pregnant women and to explore effective management strategies and a comprehensive delivery plan.\nThe clinical data of four pregnant women who were diagnosed with Moyamoya disease and admitted to our hospital between January 2010 and January 2019 were retrospectively analyzed. Their diagnosis, treatment, delivery, and postpartum management during the pregnancy were analyzed. Among the four pregnant women, three were primipara and one was multipara. The age ranged from 27 to 41 years old. The gestational week of termination of pregnancy ranged between 8 and 39 weeks. During pregnancy, one case died in utero; one case was complicated with postpartum hemorrhage; one case was complicated with chronic hypertension, multiple cerebral artery stenosis and occlusion, bilateral middle cerebral artery occlusion, bilateral internal carotid artery occlusion, and Hashimoto's thyroiditis. Under epidural anesthesia, two cases underwent a lower segment cesarean section; one case underwent artificial abortion; and one case underwent induced labor during late pregnancy. Two newborns survived.\nMoyamoya disease is a rare and serious complication of pregnancy. Pregnancy and childbirth may exacerbate the progression of this disease or induce cerebrovascular accidents, with a high mortality and disability rate, which seriously threatens the safety of mother and infant lives; however, with the close collaboration of a multidisciplinary team, it is possible to maximize a good pregnancy outcome.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics & Gynecology, Xuanwu Hospital Capital Medical University, Beijing, 100053, People's Republic of China.",
            "firstname": "Dan",
            "initials": "D",
            "lastname": "Li"
        },
        {
            "affiliation": "Department of Medical Record Statistics, Xuanwu Hospital Capital Medical University, Beijing, 100053, People's Republic of China.",
            "firstname": "Fang",
            "initials": "F",
            "lastname": "Lv"
        },
        {
            "affiliation": "Education Section, Xuanwu Hospital Capital Medical University, Beijing, 100053, People's Republic of China.",
            "firstname": "Chenyuan",
            "initials": "C",
            "lastname": "Ding"
        },
        {
            "affiliation": "Education Section, Xuanwu Hospital Capital Medical University, Beijing, 100053, People's Republic of China.",
            "firstname": "Zhaohan",
            "initials": "Z",
            "lastname": "Zhuang"
        },
        {
            "affiliation": "Department of Obstetrics & Gynecology, Xuanwu Hospital Capital Medical University, Beijing, 100053, People's Republic of China.",
            "firstname": "Shijun",
            "initials": "S",
            "lastname": "Wang"
        }
    ],
    "conclusions": "Moyamoya disease is a rare and serious complication of pregnancy. Pregnancy and childbirth may exacerbate the progression of this disease or induce cerebrovascular accidents, with a high mortality and disability rate, which seriously threatens the safety of mother and infant lives; however, with the close collaboration of a multidisciplinary team, it is possible to maximize a good pregnancy outcome.",
    "copyrights": "\u00a9 2024 Li et al.",
    "doi": "10.2147/IJWH.S472646\n10.3892/etm.2019.7198\n10.1161/STROKEAHA.107.490714\n10.1016/j.wneu.2018.10.175\n10.1097/01.AOG.0000151116.84113.56\n10.1111/jog.12336\n10.1161/01.STR.0000100479.63243.48\n10.3171/jns.2000.93.6.0976\n10.1016/j.wneu.2018.10.071\n10.21037/qims-20-830\n10.7759/cureus.10994\n10.1161/JAHA.123.030834\n10.7759/cureus.10141\n10.3349/ymj.2015.56.3.793\n10.1186/s41016-023-00318-3\n10.1016/j.neurol.2017.12.002\n10.1055/s-0037-1607430\n10.3389/fonc.2020.00085\n10.3389/fmicb.2023.1137869\n10.1213/ANE.0000000000004203\n10.1097/MD.0000000000017396\n10.3389/fped.2020.00286\n10.1111/jog.12557\n10.2176/nmc.52.304",
    "journal": "International journal of women's health",
    "keywords": [
        "cerebrovascular lesions",
        "moyamoya disease",
        "pregnancy"
    ],
    "methods": null,
    "publication_date": "2024-09-02",
    "pubmed_id": "39221426\n30867689\n18048855\n30404059\n15684147\n24689734\n14657555\n11960143\n11117870\n30347298\n33532282\n33209550\n37947101\n33014640\n25837187\n36823677\n29519672\n29270942\n32266126\n37032888\n31124843\n31577749\n32670995\n25345600\n22688067",
    "results": null,
    "title": "Pregnancy Risk Assessment, Management, and Delivery Plan for Pregnant Women with Moyamoya Disease Using a Multidisciplinary Collaborative Approach: A Case Series.",
    "xml": "<Element 'PubmedArticle' at 0x788505f3b970>"
}