{
    "abstract": "While vaginal preparation prior to hysterectomies to reduce the risk of contamination by vaginal flora is standard, there is no consensus on the appropriate choice of antisepsis agent. The aim of this study was to evaluate whether the conversion from povidone-iodine (PI) to chlorhexidine gluconate (CHG) would reduce surgical site infection (SSI) rates and improve standardized infection ratios (SIR).\nA quality improvement process was implemented to educate all providers, trainees, and staff followed by wide-spread conversion to CHG vaginal preparation prior to all hysterectomies starting on June 1, 2021. The SSI rates and SIRs were compared between the preintervention and postintervention periods.\nThere was no significant change in SSI rate or SIR from the preintervention to the postintervention period, indicating that CHG is noninferior to PI. The SSI rate was 1.53% preintervention compared to 1.57% post, and the SIR was 1.976 and 2.049, respectively.\nWhile our data suggests that the conversion from PI to CHG for vaginal prep alone is insufficient to reduce SSI rates and SIRs, it is noninferior and should be considered as part of a larger preventative bundle.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynecology, School of Medicine, University of Virginia, Charlottesville, VA. Electronic address: mnduong.md@gmail.com.",
            "firstname": "Marisa N",
            "initials": "MN",
            "lastname": "Duong"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, University of Virginia, Charlottesville, VA.",
            "firstname": "Laura N",
            "initials": "LN",
            "lastname": "Homewood"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2023 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.",
    "doi": "10.1016/j.ajic.2023.08.012",
    "journal": "American journal of infection control",
    "keywords": [
        "Gynecologic surgery",
        "Standardized infection ratios",
        "Surgical site infections",
        "Vaginal antisepsis"
    ],
    "methods": null,
    "publication_date": "2023-08-19",
    "pubmed_id": "37595639",
    "results": "There was no significant change in SSI rate or SIR from the preintervention to the postintervention period, indicating that CHG is noninferior to PI. The SSI rate was 1.53% preintervention compared to 1.57% post, and the SIR was 1.976 and 2.049, respectively.",
    "title": "Impact of converting from povidone iodine to chlorhexidine gluconate for vaginal preparation prior to hysterectomy.",
    "xml": "<Element 'PubmedArticle' at 0x788506dbb7e0>"
}