{
    "abstract": "To compare the safety and efficacy of ultrasound- and physical examination-indicated cervical cerclage in twin versus singleton gestations.\nA retrospective cohort study of all ultrasound-indicated (cervical length\u2009\u2264\u200925\u2009mm) and physical examination-indicated cerclage cases performed over a 9-year period. The primary outcome was the time interval from cerclage placement to delivery.\nThe study cohort included 94 singleton and 16 twin pregnancies. The time interval from cerclage placement to delivery was comparable in singleton and twin gestations (14.77 vs. 12.07\u2009weeks, p\u2009=\u20090.11), as were the rates of preterm births before 28 and 32\u2009weeks. The rate of alive newborns >24\u2009weeks was lower in the twin group (71.9% vs. 88.3%, p\u2009=\u20090.028). Regression analysis identified that cervical dilation, but not twin gestation, was the only factor independently associated with an increased risk for birth before 32\u2009weeks.\nUltrasound-indicated and physical examination-indicated cerclage had comparable efficacy in prolonging pregnancy in twin and singleton gestations, though live birth rates were lower in twins.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Daphna",
            "initials": "D",
            "lastname": "Amitai Komem"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Raanan",
            "initials": "R",
            "lastname": "Meyer"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Itai",
            "initials": "I",
            "lastname": "Yagel"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Daniel",
            "initials": "D",
            "lastname": "Shai"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Roy",
            "initials": "R",
            "lastname": "Mashiach"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Israel",
            "initials": "I",
            "lastname": "Hendler"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Shali",
            "initials": "S",
            "lastname": "Mazaki-Tovi"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.",
            "firstname": "Yoav",
            "initials": "Y",
            "lastname": "Yinon"
        }
    ],
    "conclusions": "Ultrasound-indicated and physical examination-indicated cerclage had comparable efficacy in prolonging pregnancy in twin and singleton gestations, though live birth rates were lower in twins.",
    "copyrights": "\u00a9 2025 The Author(s). Journal of Obstetrics and Gynaecology Research published by John Wiley & Sons Australia, Ltd on behalf of Japan Society of Obstetrics and Gynecology.",
    "doi": "10.1111/jog.16263\n10.1097/00006250-200410000-00046\n10.1111/j.1471-0528.2011.03010.x\n10.1056/NEJM199602293340904\n10.1016/j.ajog.2005.11.001\n10.1002/14651858.CD000110.pub2\n10.1097/01.AOG.0000168435.17200.53\n10.1002/uog.9093\n10.1002/uog.17457\n10.1016/0140-6736(90)90079-k\n10.1111/j.1471-0528.2012.03448.x\n10.1067/mob.2002.122126\n10.1016/j.ajog.2020.06.047\n10.1016/j.ajog.2018.11.1105\n10.1097/OGX.0000000000000422\n10.1097/GRF.0000000000000185\n10.1002/14651858.CD008991.pub2\n10.1016/j.ajog.2009.08.015\n10.1111/j.1471-0528.2007.01515.x\n10.1016/j.ajog.2019.09.038\n10.1111/j.1471-0528.1957.tb02650.x\n10.1016/j.ajog.2014.03.034\n10.3109/14767058.2015.1076786\n10.1016/j.ejogrb.2013.11.016\n10.1515/jpm-2017-0218\n10.1080/14767058.2019.1570119\n10.1080/14767058.2018.1427719",
    "journal": "The journal of obstetrics and gynaecology research",
    "keywords": [
        "bulging membranes",
        "cervical cerclage",
        "preterm birth",
        "short cervix",
        "twin gestation"
    ],
    "methods": null,
    "publication_date": "2025-03-12",
    "pubmed_id": "40070004\n15458915\n21254725\n21668771\n8569824\n16647922\n20614420\n15994635\n21739497\n28295722\n1967729\n22882759\n11967484\n32592693\n30527942\n28426125\n27015230\n22513970\n19788970\n17903224\n31586601\n13449654\n24657791\n26371753\n24321466\n29116935\n30688138\n29363371",
    "results": "The study cohort included 94 singleton and 16 twin pregnancies. The time interval from cerclage placement to delivery was comparable in singleton and twin gestations (14.77 vs. 12.07\u2009weeks, p\u2009=\u20090.11), as were the rates of preterm births before 28 and 32\u2009weeks. The rate of alive newborns >24\u2009weeks was lower in the twin group (71.9% vs. 88.3%, p\u2009=\u20090.028). Regression analysis identified that cervical dilation, but not twin gestation, was the only factor independently associated with an increased risk for birth before 32\u2009weeks.",
    "title": "Ultrasound-indicated and physical examination-indicated cervical cerclage in twin versus singleton gestations.",
    "xml": "<Element 'PubmedArticle' at 0x788503008b30>"
}