{
    "abstract": "Accumulating evidence indicates that nicotinic receptor subtypes are altered in the brains of autistic individuals, and nicotinic acetylcholine receptors (nAChRs) play essential roles in autistic profiles in BTBR T",
    "authors": [
        {
            "affiliation": "Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. sdalsharari@ksu.edu.sa.",
            "firstname": "Shakir D",
            "initials": "SD",
            "lastname": "AlSharari"
        },
        {
            "affiliation": "Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.",
            "firstname": "Hafiz M",
            "initials": "HM",
            "lastname": "Mahmood"
        },
        {
            "affiliation": "Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.",
            "firstname": "Abdullah F",
            "initials": "AF",
            "lastname": "Alasmari"
        },
        {
            "affiliation": "Department of Neuroscience, Center for Autism Research, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.",
            "firstname": "Hesham M",
            "initials": "HM",
            "lastname": "AlDhalaan"
        },
        {
            "affiliation": "Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.",
            "firstname": "Fawaz",
            "initials": "F",
            "lastname": "Alasmari"
        },
        {
            "affiliation": "Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.",
            "firstname": "Mohammad R",
            "initials": "MR",
            "lastname": "Khan"
        },
        {
            "affiliation": "Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.",
            "firstname": "Sheikh F",
            "initials": "SF",
            "lastname": "Ahmad"
        },
        {
            "affiliation": "Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.",
            "firstname": "Alanoud T",
            "initials": "AT",
            "lastname": "Aljasham"
        },
        {
            "affiliation": "Department of Pharmacology & Toxicology, Virginia Commonwealth University, Richmond, VA, USA.",
            "firstname": "Imad M",
            "initials": "IM",
            "lastname": "Damaj"
        },
        {
            "affiliation": "Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.",
            "firstname": "Musaad A",
            "initials": "MA",
            "lastname": "Alshammari"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
    "doi": "10.1007/s12035-025-04894-6\n10.1093/cercor/bhr159\n10.1016/j.neuropharm.2016.09.013\n10.1002/aur.2342\n10.3389/fimmu.2022.950275\n10.1208/s12248-009-9090-7\n10.1073/pnas.1809137115",
    "journal": "Molecular neurobiology",
    "keywords": [
        "Autism",
        "BTBR T+ Itpr3tf/J Mice",
        "Cytokines",
        "IL-1\u03b2",
        "NAChRs",
        "Nicotine",
        "Nicotinic Acetylcholine Receptors",
        "TNF-\u03b1"
    ],
    "methods": null,
    "publication_date": "2025-04-02",
    "pubmed_id": "40172818\n29701730\n26183723\n11431227\n22925690\n23307081\n25639674\n15046869\n21402717\n21810785\n23638000\n27638450\n32691528\n26337613\n20705131\n22918031\n15546155\n22748016\n24117055\n21647375\n15653325\n17804539\n16357100\n17913903\n20877284\n11803234\n19157572\n23604965\n23231720\n20032969\n31811869\n24491952\n19941908\n17559418\n30213685\n17097158\n26596563\n23523478\n23115221\n15365686\n15159130\n28623168\n11303054\n22852821\n28668513\n23050259\n22175527\n18958184\n31486397\n11245666\n22323734\n4022267\n21482353\n17670967\n8402163\n4009168\n2200178\n24378908\n19280351\n18378158\n30297392",
    "results": null,
    "title": "Nicotine Attenuates Molecular Signalings in the BTBR T",
    "xml": "<Element 'PubmedArticle' at 0x788505c09ee0>"
}