{
    "abstract": "To investigate the effect of respiratory motion in terms of signal loss in prostate diffusion-weighted imaging (DWI), and to evaluate the usage of partial Fourier in a free-breathing protocol in a clinically relevant b-value range using both single-shot and multi-shot acquisitions.\nA controlled breathing DWI acquisition was first employed at 3\u00a0T to measure signal loss from deep breathing patterns. Single-shot and multi-shot (2-shot) acquisitions without partial Fourier (no pF) and with partial Fourier (pF) factors of 0.75 and 0.65 were employed in a free-breathing protocol. The apparent SNR and ADC values were evaluated in 10 healthy subjects to measure if low pF factors caused low apparent SNR or overestimated ADC.\nControlled breathing experiments showed a difference in signal coefficient of variation between shallow and deep breathing. In free-breathing single-shot acquisitions, the pF 0.65 scan showed a significantly (p\u2009<\u20090.05) higher apparent SNR than pF 0.75 and no pF in the peripheral zone (PZ) of the prostate. In the multi-shot acquisitions in the PZ, pF 0.75 had a significantly higher apparent SNR than 0.65 pF and no pF. The single-shot pF 0.65 scan had a significantly lower ADC than single-shot no pF.\nDeep breathing patterns can cause intravoxel dephasing in prostate DWI. For single-shot acquisitions at a b-value of 800\u00a0s/mm",
    "authors": [
        {
            "affiliation": "Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany. sean.mctavish@tum.de.",
            "firstname": "Sean",
            "initials": "S",
            "lastname": "McTavish"
        },
        {
            "affiliation": "Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.",
            "firstname": "Anh T",
            "initials": "AT",
            "lastname": "Van"
        },
        {
            "affiliation": "Philips Healthcare, Best, Netherlands.",
            "firstname": "Johannes M",
            "initials": "JM",
            "lastname": "Peeters"
        },
        {
            "affiliation": "Philips GmbH, Hamburg, Germany.",
            "firstname": "Kilian",
            "initials": "K",
            "lastname": "Weiss"
        },
        {
            "affiliation": "Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.",
            "firstname": "Felix N",
            "initials": "FN",
            "lastname": "Harder"
        },
        {
            "affiliation": "Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.",
            "firstname": "Marcus R",
            "initials": "MR",
            "lastname": "Makowski"
        },
        {
            "affiliation": "Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.",
            "firstname": "Rickmer F",
            "initials": "RF",
            "lastname": "Braren"
        },
        {
            "affiliation": "Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.",
            "firstname": "Dimitrios C",
            "initials": "DC",
            "lastname": "Karampinos"
        }
    ],
    "conclusions": "Deep breathing patterns can cause intravoxel dephasing in prostate DWI. For single-shot acquisitions at a b-value of 800\u00a0s/mm",
    "copyrights": "\u00a9 2024. The Author(s).",
    "doi": "10.1007/s10334-024-01162-x",
    "journal": "Magma (New York, N.Y.)",
    "keywords": [
        "Apparent diffusion coefficient (ADC) mapping",
        "Diffusion-weighted imaging",
        "Multi-shot EPI",
        "Prostate imaging",
        "Single-shot echo planar imaging (EPI)"
    ],
    "methods": null,
    "publication_date": "2024-05-15",
    "pubmed_id": "38743376\n23172614\n24840072\n22249194\n19007373\n24468511\n20308476\n21182135\n25408104\n24951199\n28194821\n22535706\n18383294\n18222812\n17326165\n24925000\n30859628\n34142375\n26547123\n31923466\n26900872\n34894335\n22987784\n30394568\n36098347\n31765063\n33048401\n12111937\n26033456\n15890582\n28444802\n31625663\n22851517\n9469714\n18581353\n28862352\n29678540\n34554579\n35944809\n31335699\n22592941\n17980534\n20577977\n19449372\n25753774\n28608411\n8722828\n23370063\n27550212\n16276497\n15562493\n25394325\n25648591\n27520840\n36168032\n35583823\n32515678\n32064561\n20640899\n33735931\n32424596\n35596009\n34825741\n30024051\n23908146\n25360990",
    "results": "Controlled breathing experiments showed a difference in signal coefficient of variation between shallow and deep breathing. In free-breathing single-shot acquisitions, the pF 0.65 scan showed a significantly (p\u2009<\u20090.05) higher apparent SNR than pF 0.75 and no pF in the peripheral zone (PZ) of the prostate. In the multi-shot acquisitions in the PZ, pF 0.75 had a significantly higher apparent SNR than 0.65 pF and no pF. The single-shot pF 0.65 scan had a significantly lower ADC than single-shot no pF.",
    "title": "Partial Fourier in the presence of respiratory motion in prostate diffusion-weighted echo planar imaging.",
    "xml": "<Element 'PubmedArticle' at 0x788503e99030>"
}