{
    "abstract": "Platypnea orthodeoxia syndrome (POS) is a rare cause of hypoxemia. Diagnosis of POS is challenging, requiring a high index of clinical suspicion, special investigations, and collaboration with multiple specialists.\nWe describe an 86-yr-old male who presented to the emergency department with hip pain after a witnessed fall. He was noted to be hypoxemic at presentation with a peripheral oxygen saturation (SpO\nPlatypnea orthodeoxia syndrome is a rare presentation of hypoxemia. Positional changes in oxygenation are the cardinal feature of POS. Discordance between lung imaging and the severity of hypoxemia should prompt investigation for an intracardiac shunt, which can occur in POS even in the absence of increased right-sided heart pressures. Either contrast TTE or transesophageal echocardiography is necessary to make this diagnosis.\nR\u00e9SUM\u00e9: OBJECTIF: Le syndrome de platypn\u00e9e-orthod\u00e9oxie (SPO) est une cause rare d\u2019hypox\u00e9mie. Le diagnostic de SPO est difficile \u00e0 poser, n\u00e9cessitant un indice \u00e9lev\u00e9 de suspicion clinique, des investigations sp\u00e9ciales et la collaboration de plusieurs sp\u00e9cialistes. CARACT\u00e9RISTIQUES CLINIQUES: Nous d\u00e9crivons un homme de 86 ans qui s\u2019est pr\u00e9sent\u00e9 au service des urgences avec une douleur \u00e0 la hanche apr\u00e8s une chute av\u00e9r\u00e9e. Il \u00e9tait hypox\u00e9mique au moment de sa pr\u00e9sentation, avec une saturation p\u00e9riph\u00e9rique en oxyg\u00e8ne (SpO",
    "authors": [
        {
            "affiliation": "Department of Critical Care Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.\nDepartment of Respirology, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.\nDivision of Critical Care Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.",
            "firstname": "Vorakamol",
            "initials": "V",
            "lastname": "Phoophiboon"
        },
        {
            "affiliation": "Department of Critical Care Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.\nDepartment of Respirology, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.\nDepartment of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.\nKeenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.",
            "firstname": "Samir",
            "initials": "S",
            "lastname": "Gupta"
        },
        {
            "affiliation": "Department of Critical Care Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.\nDepartment of Respirology, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.\nDepartment of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.\nKeenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.",
            "firstname": "Jane",
            "initials": "J",
            "lastname": "Batt"
        },
        {
            "affiliation": "Department of Critical Care Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada. karen.burns@unityhealth.to.\nDepartment of Respirology, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada. karen.burns@unityhealth.to.\nDepartment of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. karen.burns@unityhealth.to.\nKeenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada. karen.burns@unityhealth.to.\nInterdepartmental Division of Critical Care Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. karen.burns@unityhealth.to.\nDepartment of Health Research Methods, Evidence, and Impact (HEI), McMaster University, Hamilton, ON, Canada. karen.burns@unityhealth.to.\nInterdepartmental Division of Critical Care, University of Toronto, Unity Health Toronto-St. Michael's Hospital, 30 Bond Street, Room 4-045 Donnelly Wing, Toronto, ON, M5B 1W8, Canada. karen.burns@unityhealth.to.",
            "firstname": "Karen E A",
            "initials": "KEA",
            "lastname": "Burns"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2024. Canadian Anesthesiologists' Society.\n\u00a9 2024. Canadian Anesthesiologists' Society.",
    "doi": "10.1007/s12630-024-02854-7\n10.1183/09031936.00037014\n10.24875/acm.21000171\n10.1378/chest.112.6.1449\n10.1152/ajplegacy.1949.159.3.551\n10.1016/j.rmed.2017.05.016\n10.1111/imj.15669\n10.1016/0002-9149(82)90263-6\n10.1016/0735-1097(91)90775-5\n10.1016/s0735-1097(84)80106-0\n10.3109/15412551003631717\n10.1378/chest.95.4.901\n10.1183/13993003.01647-2019\n10.1056/nejmra0707185\n10.5152/dir.2021.20474\n10.1002/ajh.26340\n10.1016/0002-9149(87)90271-2\n10.1016/s0735-1097(01)01427-9\n10.1038/nrcardio.2010.224\n10.3389/fneur.2020.00281\n10.1152/ajplegacy.1972.222.5.1285\n10.1161/circ.105.6.e47\n10.1136/openhrt-2019-001150\n10.15420/icr.2019.27\n10.1016/j.jcin.2016.07.003\n10.1002/1522-726x(200009)51:1<120::aid-ccd27>3.0.co;2-d",
    "journal": "Canadian journal of anaesthesia = Journal canadien d'anesthesie",
    "keywords": [
        "hypoxemia",
        "patent foramen ovale",
        "platypnea orthodeoxia syndrome",
        "shunt"
    ],
    "methods": null,
    "publication_date": "2024-10-29",
    "pubmed_id": "39467992\n25063240\n34428199\n9404736\n28732833\n7081065\n1894856\n6470340\n20397812\n2647425\n31473594\n18509123\n34914605\n34467556\n3618511\n11527606\n21283148\n32411074\n5022387\n11839642\n32763965\n33318751\n27659570\n10973034",
    "results": null,
    "title": "A patient with unexplained hypoxemia after a fall diagnosed with platypnea orthodeoxia syndrome: approaches to resolving discrepancies between level of hypoxemia and clinical presentation.",
    "xml": "<Element 'PubmedArticle' at 0x7885035ec310>"
}