{
    "abstract": "The correct type and time of follow-up for patients affected by COVID19 ARDS is still unclear. The aim of this study was to evaluate at the survivors to COVID19 ARDS requiring non-invasive respiratory support (NRS) admitted to a Respiratory Intensive care unit (RICU) from March 8th till May 31th 2020 looking at all sequelae via a comprehensive follow up. All patients underwent a multi-disciplinary instrumental and clinical assessment within three months form admission to evaluate all infection related sequelae. Thirty-eight patients were enrolled Lung-Ultrasound (LUS) showed an outstanding discrimination ability (ROC AUC: 0.95) and a substantial agreement rate (Cohen's K: 0.74) compared to chest CT-scan detecting improvement of lung consolidations. Youden's test showed a cut-off pressure of 11 cmH2O ExpiratoryPAP-Continuous-PAP-max (EPAP-CPAP) applied at the airways during hospitalization to be significantly correlated (p value: 0.026) to the increased pulmonary artery common trunk diameter. A total of 8/38 patients (21.8%), 2 of whom during follow-up, were diagnosed with Pulmonary Emboli (PE) and started anticoagulant treatment. Patients with PE had a statistically significant shorter length of time of hospitalization, time to negative swab, CPAP/NIV duration, P/F ratio and D-dimers at follow-up compared to non PE. A comprehensive approach to patients with ARDS COVID19 requiring NRS is necessary. This study highlighted cardiopulmonary impairment related to the ARDS and to the high-EPAP-CPAP-max greater than 11mmHg provided during admission, the usefulness of LUS in monitoring post-infection recovery and the correct identification and\u00a0 treatment of patients with PE during follow up.",
    "authors": [
        {
            "affiliation": "Cardio Thoracic and Vascular Department, University Hospital Policlinic of Bari. lucreziademichele@libero.it.",
            "firstname": "Lucrezia",
            "initials": "L",
            "lastname": "De Michele"
        },
        {
            "affiliation": "Cardiothoracic Department, Respiratory and Critical Care Unit, Bari Policlinic University Hospital, Bari; Section of Respiratory Diseases, Department of Basic Medical Science Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari. paola.pierucci@policlinico.ba.it.",
            "firstname": "Paola",
            "initials": "P",
            "lastname": "Pierucci"
        },
        {
            "affiliation": "Department of Biomedical Sciences and Human Oncology, University of Bari 'Aldo Moro' Medical School, Bari . guidogiovannettijr@gmail.com.",
            "firstname": "Guido",
            "initials": "G",
            "lastname": "Giovannetti"
        },
        {
            "affiliation": "DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari 'Aldo Moro' Medical School, Bari . micheledeceglie@libero.it.",
            "firstname": "Michele",
            "initials": "M",
            "lastname": "De Ceglie"
        },
        {
            "affiliation": "Section of Respiratory Diseases, Department of Basic Medical Science Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari. michela.dimitri88@gmail.com.",
            "firstname": "Michela",
            "initials": "M",
            "lastname": "Dimitri"
        },
        {
            "affiliation": "DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari 'Aldo Moro' Medical School, Bari . alemira7@gmail.com.",
            "firstname": "Alessandra",
            "initials": "A",
            "lastname": "Mirabile"
        },
        {
            "affiliation": "Respiratory Unit, Di Venere Hospital, Bari. vitalianonicola.40@gmail.com.",
            "firstname": "Vitaliano",
            "initials": "V",
            "lastname": "Quaranta"
        },
        {
            "affiliation": "DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari 'Aldo Moro' Medical School, Bari. arnaldo.scardapane@gmail.com.",
            "firstname": "Arnaldo",
            "initials": "A",
            "lastname": "Scardapane"
        },
        {
            "affiliation": "DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, University of Bari 'Aldo Moro' Medical School, Bari. carlo.dagostino@policlinico.ba.it.",
            "firstname": "Carlo",
            "initials": "C",
            "lastname": "D'Agostino"
        },
        {
            "affiliation": "Cardiothoracic Department, Respiratory and Critical Care Unit, Bari Policlinic University Hospital, Bari. elisiana.carpagnano@uniba.it.",
            "firstname": "Giovanna Elisiana",
            "initials": "GE",
            "lastname": "Carpagnano"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.4081/monaldi.2022.2142",
    "journal": "Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace",
    "keywords": [],
    "methods": null,
    "publication_date": "2022-01-20",
    "pubmed_id": "35044135",
    "results": null,
    "title": "Post severe COVID-19 infection lung damages study. The experience of early three months multidisciplinary follow-up.",
    "xml": "<Element 'PubmedArticle' at 0x788504e08680>"
}