{
    "abstract": "Lysosomal acid sphingomyelinase (ASM; SMPD1) deficiency causes Niemann-Pick Disease (NPD) that, in Type B, manifests with interstitial lung disease and susceptibility to infections. Constitutional ",
    "authors": [
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.\nUniversity of Colorado Anschutz Medical Campus, Medicine, Aurora, Colorado, United States.",
            "firstname": "Joanna",
            "initials": "J",
            "lastname": "Poczobutt"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.",
            "firstname": "Nicholas",
            "initials": "N",
            "lastname": "Egersdorf"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.",
            "firstname": "Max S",
            "initials": "MS",
            "lastname": "Hiltabidle"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.",
            "firstname": "Koichi",
            "initials": "K",
            "lastname": "Nishino"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.",
            "firstname": "Matthew J",
            "initials": "MJ",
            "lastname": "Justice"
        },
        {
            "affiliation": "National Jewish Health, Denver, Colorado, United States.",
            "firstname": "Tanner",
            "initials": "T",
            "lastname": "Rivera"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.",
            "firstname": "Betty",
            "initials": "B",
            "lastname": "Dubois"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.",
            "firstname": "Alexander",
            "initials": "A",
            "lastname": "Borowiec"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.",
            "firstname": "S Ali",
            "initials": "SA",
            "lastname": "Mousavi-Aghdas"
        },
        {
            "affiliation": "National Jewish Health Department of Medicine, Denver, Colorado, United States.",
            "firstname": "Katrina",
            "initials": "K",
            "lastname": "Kopf"
        },
        {
            "affiliation": "National Jewish Health, Immunology and Genomic Medicine, Denver, Colorado, United States.\nUniversity of Colorado Anschutz Medical Campus, Medicine, Aurora, Colorado, United States.",
            "firstname": "Fabienne",
            "initials": "F",
            "lastname": "Gally"
        },
        {
            "affiliation": "National Jewish Health, Mouse Genetics Core Facility, Denver, Colorado, United States.\nUniversity of Colorado Anschutz Medical Campus, Medicine, Aurora, Colorado, United States.",
            "firstname": "Jennifer",
            "initials": "J",
            "lastname": "Matsuda"
        },
        {
            "affiliation": "National Jewish Health, Denver, Colorado, United States.",
            "firstname": "Evgeny V",
            "initials": "EV",
            "lastname": "Berdyshev"
        },
        {
            "affiliation": "National Jewish Health, Medicine, Denver, Colorado, United States.\nUniversity of Colorado Anschutz Medical Campus, Medicine, Aurora, Colorado, United States; petrachei@njhealth.org.",
            "firstname": "Irina",
            "initials": "I",
            "lastname": "Petrache"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1165/rcmb.2024-0380OC",
    "journal": "American journal of respiratory cell and molecular biology",
    "keywords": [
        "ceramide",
        "conditional knockout",
        "endothelium",
        "lung repair",
        "sphingolipids"
    ],
    "methods": null,
    "publication_date": "2025-02-07",
    "pubmed_id": "39918923",
    "results": null,
    "title": "Short Term Acid Sphingomyelinase Deficiency Exerts Proinflammatory and Antiapoptotic Effects During LPS-induced Lung Injury in Mice.",
    "xml": "<Element 'PubmedArticle' at 0x788503ff4a40>"
}