{
    "abstract": "The aim of this systematic review was to identify principles of exercise interventions associated with improved physical function, weight management or musculoskeletal pain relief among young and middle-aged adults with obesity and propose an evidence-based exercise prescription that could assist in secondary prevention of osteoarthritis.\nA structured electronic review was conducted using MEDLINE, PubMed, and SPORTDiscus. The search string included 1) \"obes*\" AND \"exercise\" AND \"interven*\" AND \"musculoskeletal pain OR knee pain OR hip pain\". Studies 1) were randomized controlled trials of humans, with a non-exercise control, 2) included participants aged 18-50\u2009years, and 3) had outcomes that included physical function, musculoskeletal pain, and/or body composition. Studies were excluded if participants had peri-menopausal status, cancer, or obesity-related co-morbidities. A recommended exercise prescription was developed based on common principles used in the included exercise interventions with greatest change in function or pain.\nSeven studies were included. Similarities in exercise intensity (40-80% VO\nCommon principles in exercise prescription for improvements in weight management, physical function and pain relief among otherwise healthy people with obesity. Exercise prescription including moderate intensity exercise for 30-60\u2009min, three times per week can be considered an effective treatment for weight management and obesity-related musculoskeletal symptoms. Exercise should be recommended to at-risk individuals as part of secondary prevention of osteoarthritis.",
    "authors": [
        {
            "affiliation": "School of Sport, Exercise and Nutrition, Massey University, Wellington, New Zealand.",
            "firstname": "Dylan R",
            "initials": "DR",
            "lastname": "Barrow"
        },
        {
            "affiliation": "Geriatric Research, Education, and Clinical Center, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA.\nDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA.",
            "firstname": "Lauren M",
            "initials": "LM",
            "lastname": "Abbate"
        },
        {
            "affiliation": "School of Health Studies, University of Memphis, Memphis, TN, USA.",
            "firstname": "Max R",
            "initials": "MR",
            "lastname": "Paquette"
        },
        {
            "affiliation": "Division of Rheumatology, Allergy & Immunology, Tufts Medical Center, Boston, MA, USA.",
            "firstname": "Jeffrey B",
            "initials": "JB",
            "lastname": "Driban"
        },
        {
            "affiliation": "UF Health Sports Performance Center, Department of Orthopedics and Rehabilitation, University of Florida, Gainesville, FL, USA.",
            "firstname": "Heather K",
            "initials": "HK",
            "lastname": "Vincent"
        },
        {
            "affiliation": "Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, New York University School of Medicine, New York, NY, USA.",
            "firstname": "Connie",
            "initials": "C",
            "lastname": "Newman"
        },
        {
            "affiliation": "Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.",
            "firstname": "Stephen P",
            "initials": "SP",
            "lastname": "Messier"
        },
        {
            "affiliation": "Osteoarthritis Action Alliance, Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA.",
            "firstname": "Kirsten R",
            "initials": "KR",
            "lastname": "Ambrose"
        },
        {
            "affiliation": "School of Sport, Exercise and Nutrition, Massey University, Wellington, New Zealand. shultzsarah@seattleu.edu.\nDepartment of Kinesiology, Seattle University, 901 12th Avenue, Seattle, WA, 98122, USA. shultzsarah@seattleu.edu.",
            "firstname": "Sarah P",
            "initials": "SP",
            "lastname": "Shultz"
        }
    ],
    "conclusions": "Common principles in exercise prescription for improvements in weight management, physical function and pain relief among otherwise healthy people with obesity. Exercise prescription including moderate intensity exercise for 30-60\u2009min, three times per week can be considered an effective treatment for weight management and obesity-related musculoskeletal symptoms. Exercise should be recommended to at-risk individuals as part of secondary prevention of osteoarthritis.",
    "copyrights": null,
    "doi": "10.1186/s12891-019-3004-3\n10.1073/pnas.1703856114\n10.15585/mmwr.mm6609e1\n10.1097/BOR.0000000000000161\n10.1002/acr.22714\n10.1038/nrrheum.2015.135\n10.1682/JRRD.2014.08.0199\n10.2105/AJPH.2007.124495\n10.1016/j.joca.2015.07.023\n10.1249/MSS.0b013e3181949333\n10.1016/j.pmrj.2010.04.004\n10.3129/i08-001\n10.1152/japplphysiol.00306.2015\n10.1186/s12955-017-0743-4\n10.1080/02640414.2015.1112022\n10.7326/0003-4819-133-2-200007180-00008\n10.1123/ijsn.8.3.213\n10.1097/00005768-200201000-00015\n10.1002/acr.23013",
    "journal": "BMC musculoskeletal disorders",
    "keywords": [
        "Musculoskeletal pain",
        "Obesity",
        "Physical activity",
        "Physical function"
    ],
    "methods": null,
    "publication_date": "2019-12-22",
    "pubmed_id": "31861990\n28808025\n26633046\n28278145\n25775186\n18426630\n28422077\n26359653\n26439406\n26237073\n25826793\n18556608\n26254237\n19127177\n20709301\n18347620\n26112241\n28647284\n28836987\n26571136\n10896648\n9738131\n11782653\n27563831\n11427759",
    "results": "Seven studies were included. Similarities in exercise intensity (40-80% VO",
    "title": "Exercise prescription for weight management in obese adults at risk for osteoarthritis: synthesis from a systematic review.",
    "xml": "<Element 'PubmedArticle' at 0x788502e9e160>"
}