{
    "abstract": "One-lung ventilation (OLV) has two major challenges: oxygenation and lung protection. The former is mainly because the ventilation of one lung is stopped while the perfusion continues; the latter is mainly because the whole ventilation is applied to only one lung. Recommendations for maintaining the oxygenation and methods of lung protection can contradict each other (such as high vs. low inspiratory oxygen fraction (FiO2), high vs. low tidal volume (TV), etc.). In light of the (very few) randomized clinical trials, this review focuses on a recent strategy for OLV, which includes a possible decrease in FiO2, lower TVs, positive end-expiratory pressure (PEEP) to the dependent lung, continuous positive airway pressure (CPAP) to the non-dependent lung and recruitment manoeuvres. Other applications such as anaesthetic choice and fluid management can affect the success of ventilatory strategy; new developments have changed the classical approach in this respect.",
    "authors": [
        {
            "affiliation": "Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey. Electronic address: senturkm@istanbul.edu.tr.",
            "firstname": "Mert",
            "initials": "M",
            "lastname": "\u015eent\u00fcrk"
        },
        {
            "affiliation": "University of Toronto, Toronto, Canada. Electronic address: Peter.Slinger@uhn.ca.",
            "firstname": "Peter",
            "initials": "P",
            "lastname": "Slinger"
        },
        {
            "affiliation": "The Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: edmond.cohen@mountsinai.org.",
            "firstname": "Edmond",
            "initials": "E",
            "lastname": "Cohen"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.",
    "doi": "10.1016/j.bpa.2015.08.001",
    "journal": "Best practice & research. Clinical anaesthesiology",
    "keywords": [
        "mechanical ventilation",
        "one-lung ventilation",
        "pulmonary gas exchange"
    ],
    "methods": null,
    "publication_date": "2015-12-09",
    "pubmed_id": "26643100",
    "results": null,
    "title": "Intraoperative mechanical ventilation strategies for one-lung ventilation.",
    "xml": "<Element 'PubmedArticle' at 0x788506609f30>"
}