{
    "abstract": "Prolactinomas resulting in pituitary apoplexy are an uncommon obstetrical complication. The hemorrhage can cause compression and necrosis of the pituitary gland as well as the optic chiasm, necessitating surgical intervention.\nA 35-year-old woman, G0, presented for an infertility consult with a prior diagnosis of polycystic ovarian syndrome. Evaluation for oligomenorrhea found an elevated prolactin level of 69.76\u00a0ng/mL, an elevated DHEA-S of 524, and HgbA1c of 5.7%. The patient denied visual or neurological symptoms. Infertility treatment was started, and magnetic resonance imaging (MRI) of the brain was recommended; however, the patient forewent imaging. Within a few months, she was pregnant. At 27\u00a0weeks of gestation, the patient developed sudden visual field loss to the right eye and presented to her optometrist. MRI of the pituitary identified a sellar mass with suprasellar extension, consistent with a recently hemorrhaged pituitary macroadenoma or pituitary apoplexy with displacement of the optic chiasm. Due to the risks of permanent optic nerve damage, the patient underwent endoscopic endonasal transsphenoidal hypophysectomy with intraoperative fetal monitoring at 30\u00a0weeks 1\u00a0day of gestation. At 39\u00a0weeks of gestation a cesarean section was performed due to the recent procedure. Her delivery and postpartum period were without complications.\nPituitary apoplexy presenting in pregnancy is a rare and potentially life-threatening disorder due to an acute ischemic infarction or hemorrhage of the pituitary gland. Surgical management of the pituitary gland in pregnancy is rarely recommended, except in cases of severe visual disturbance and uncontrolled Cushing's disease.",
    "authors": [
        {
            "affiliation": "University of North Dakota School of Medicine and Health Sciences, Department of Obstetrics and Gynecology, Northeast Campus, 1301 N Columbia Rd, Grand Forks, ND 58203, USA.",
            "firstname": "Megan",
            "initials": "M",
            "lastname": "Corn"
        },
        {
            "affiliation": "University of North Dakota School of Medicine and Health Sciences, Department of Obstetrics and Gynecology, Southeast Campus, 1301 N Columbia Rd, Grand Forks, ND 58203, USA.",
            "firstname": "Austin",
            "initials": "A",
            "lastname": "Nickell"
        },
        {
            "affiliation": "Altru Health System, Department of Obstetrics and Gynecology, 1000 S Columbia Rd, Grand Forks, ND 58201, USA.",
            "firstname": "Collette",
            "initials": "C",
            "lastname": "Lessard"
        },
        {
            "affiliation": "Sanford Health System, Department of Neurosurgery, 2301 25th St S, Fargo, ND 58103, USA.",
            "firstname": "Adam",
            "initials": "A",
            "lastname": "Jackson"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2023 The Author(s). Published by Elsevier B.V.",
    "doi": "10.1016/j.crwh.2023.e00543\n10.3389/fendo.2015.00085\n10.1016/s0002-9343(88)80346-2\n10.1155/2014/397131\n10.1016/j.ando.2016.04.001\n10.1007/s11102-019-01004-3\n10.4103/ijem.IJEM_8_17\n10.1111/j.1365-2265.2010.03913.x\n10.1093/ons/opy219\n10.3389/fneur.2021.614382\n10.3171/2017.2.JNS1784",
    "journal": "Case reports in women's health",
    "keywords": [
        "COVID-19",
        "Case report",
        "Endoscopic endonasal transsphenoidal hypophysectomy",
        "Pituitary gland",
        "Prolactinoma",
        "Third trimester"
    ],
    "methods": null,
    "publication_date": "2023-09-29",
    "pubmed_id": "37771424\n26074878\n3400697\n25374951\n27130071\n0\n31691893\n15683096\n28553611\n21044119\n30124966\n33833725\n28946177",
    "results": null,
    "title": "Pituitary apoplexy during pregnancy with transsphenoidal resection and intraoperative fetal monitoring: A case report.",
    "xml": "<Element 'PubmedArticle' at 0x7885036e3a60>"
}