{
    "abstract": "The bone marrow adjusts blood cell production to meet physiological demands in response to insults. The spatial organization of normal and stress responses are unknown owing to the lack of methods to visualize most steps of blood production. Here we develop strategies to image multipotent haematopoiesis, erythropoiesis and lymphopoiesis in mice. We combine these with imaging of myelopoiesis",
    "authors": [
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. wuqingqing@ustc.edu.cn.\nDepartment of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. wuqingqing@ustc.edu.cn.",
            "firstname": "Qingqing",
            "initials": "Q",
            "lastname": "Wu"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.\nDepartment of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.",
            "firstname": "Jizhou",
            "initials": "J",
            "lastname": "Zhang"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.",
            "firstname": "Sumit",
            "initials": "S",
            "lastname": "Kumar"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.",
            "firstname": "Siyu",
            "initials": "S",
            "lastname": "Shen"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.",
            "firstname": "Morgan",
            "initials": "M",
            "lastname": "Kincaid"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.",
            "firstname": "Courtney B",
            "initials": "CB",
            "lastname": "Johnson"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.",
            "firstname": "Yanan Sophia",
            "initials": "YS",
            "lastname": "Zhang"
        },
        {
            "affiliation": "Center for Systems Biology and Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.\nRuth L. and David S. Gottesman Institute for Stem Cell, Regenerative Medicine Research, Department of Cell Biology and Stem Cell Institute, Albert Einstein College of Medicine, Bronx, NY, USA.",
            "firstname": "Rapha\u00ebl",
            "initials": "R",
            "lastname": "Turcotte"
        },
        {
            "affiliation": "Center for Systems Biology and Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.",
            "firstname": "Clemens",
            "initials": "C",
            "lastname": "Alt"
        },
        {
            "affiliation": "Ruth L. and David S. Gottesman Institute for Stem Cell, Regenerative Medicine Research, Department of Cell Biology and Stem Cell Institute, Albert Einstein College of Medicine, Bronx, NY, USA.",
            "firstname": "Kyoko",
            "initials": "K",
            "lastname": "Ito"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.",
            "firstname": "Shelli",
            "initials": "S",
            "lastname": "Homan"
        },
        {
            "affiliation": "Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.",
            "firstname": "Bryan E",
            "initials": "BE",
            "lastname": "Sherman"
        },
        {
            "affiliation": "Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.\nImmunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.",
            "firstname": "Tzu-Yu",
            "initials": "TY",
            "lastname": "Shao"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.\nImmunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.",
            "firstname": "Anastasiya",
            "initials": "A",
            "lastname": "Slaughter"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.\nImmunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.",
            "firstname": "Benjamin",
            "initials": "B",
            "lastname": "Weinhaus"
        },
        {
            "affiliation": "Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.\nDivision of Immunobiology and Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.",
            "firstname": "Baobao",
            "initials": "B",
            "lastname": "Song"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.\nDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.",
            "firstname": "Marie Dominique",
            "initials": "MD",
            "lastname": "Filippi"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.\nDivision of Immunobiology and Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.\nDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.",
            "firstname": "H Leighton",
            "initials": "HL",
            "lastname": "Grimes"
        },
        {
            "affiliation": "Advanced Microscopy Program, Center for Systems Biology and Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.\nHarvard Stem Cell Institute, Cambridge, MA, USA.",
            "firstname": "Charles P",
            "initials": "CP",
            "lastname": "Lin"
        },
        {
            "affiliation": "Ruth L. and David S. Gottesman Institute for Stem Cell, Regenerative Medicine Research, Department of Cell Biology and Stem Cell Institute, Albert Einstein College of Medicine, Bronx, NY, USA.\nDepartment of Medicine, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY, USA.",
            "firstname": "Keisuke",
            "initials": "K",
            "lastname": "Ito"
        },
        {
            "affiliation": "Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.\nDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.",
            "firstname": "Sing Sing",
            "initials": "SS",
            "lastname": "Way"
        },
        {
            "affiliation": "Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.\nDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.",
            "firstname": "J Matthew",
            "initials": "JM",
            "lastname": "Kofron"
        },
        {
            "affiliation": "Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. daniel.lucas@cchmc.org.\nDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. daniel.lucas@cchmc.org.",
            "firstname": "Daniel",
            "initials": "D",
            "lastname": "Lucas"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2024. The Author(s).",
    "doi": "10.1038/s41586-024-07186-6\n10.1038/s41586-021-03201-2\n10.1007/s40778-020-00177-z\n10.3389/fimmu.2016.00502\n10.1038/nature21693\n10.1016/j.stem.2018.11.022\n10.1182/blood.2020006574\n10.1038/s41586-021-03298-5\n10.1038/s41586-020-1971-z\n10.1016/j.stem.2020.06.003\n10.1182/blood-2008-12-195644\n10.1038/nature07434\n10.1016/1074-7613(94)90037-X\n10.1038/35004599\n10.1016/S0092-8674(00)80453-5\n10.1016/j.stem.2007.07.005\n10.1016/j.immuni.2017.10.021\n10.1016/j.stem.2015.05.003\n10.1182/blood-2008-07-167106\n10.1371/journal.pone.0154189\n10.1016/j.exphem.2015.12.010\n10.1073/pnas.0909296106\n10.4049/jimmunol.1600297\n10.1016/j.devcel.2021.05.018\n10.1016/j.immuni.2016.11.004\n10.1038/nature15250\n10.1016/j.cell.2005.05.026\n10.1038/nature12612\n10.1038/s41598-017-02896-6\n10.1038/nature25741\n10.1016/j.cell.2010.09.016\n10.1084/jem.20180778\n10.1084/jem.20192070\n10.1371/journal.pone.0019957\n10.1038/nm.3155\n10.1016/j.jim.2009.06.008\n10.1182/blood-2010-02-268466",
    "journal": "Nature",
    "keywords": [],
    "methods": null,
    "publication_date": "2024-03-21",
    "pubmed_id": "38509363\n33568812\n32837857\n27895645\n28355185\n30661958\n32766876\n33627868\n32025033\n32589864\n19357397\n19052546\n7541305\n10724173\n9393859\n18371379\n29166589\n26095048\n19096010\n27111450\n26774386\n19805084\n27456481\n34146467\n27913094\n26416744\n15989959\n24107994\n28634334\n29466336\n20887898\n30158115\n34709350\n21655273\n23644514\n19567251\n20647571",
    "results": null,
    "title": "Resilient anatomy and local plasticity of naive and stress haematopoiesis.",
    "xml": "<Element 'PubmedArticle' at 0x788505cf8810>"
}