{
    "abstract": "\u2003The ABO blood group system is linked to hemostasis via its relationship with von Willebrand factor (VWF) and factor VIII (FVIII). In the current study, we investigated the association of the ABO system with clinical outcomes as well as VWF and platelet function in patients with left ventricular assist devices (LVADs).\n\u2003Bleeding and thromboembolic complications were assessed in 111 patients during 1 year after LVAD implantation. In 67 LVAD patients, VWF antigen, VWF activity, VWF ristocetin cofactor, VWF collagen-binding, and FVIII activity were assessed. Platelet surface P-selectin and activated glycoprotein IIb/IIIa were determined by flow cytometry, and soluble P-selectin was measured with an enzyme-linked immunoassay. Platelet aggregation was assessed by light transmission and impedance aggregometry.\n\u2003Thirty-six patients (32.4%) experienced a bleeding and 22 patients (19.8%) a thromboembolic event. In univariate analyses, patients with blood group O had numerically more bleeding complications and less thromboembolic events as compared to patients with blood group non-O (both \n\u2003Patients with blood group O had significantly lower levels of VWF and FVIII (all ",
    "authors": [
        {
            "affiliation": "Department of Internal Medicine, Cardiology and Nephrology, Landesklinikum Wiener Neustadt, Wiener Neustadt, Austria.\nDepartment of Internal Medicine II, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Maximilian",
            "initials": "M",
            "lastname": "Tscharre"
        },
        {
            "affiliation": "Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Franziska",
            "initials": "F",
            "lastname": "Wittmann"
        },
        {
            "affiliation": "Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Daniela",
            "initials": "D",
            "lastname": "Kitzmantl"
        },
        {
            "affiliation": "Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Thomas",
            "initials": "T",
            "lastname": "Schl\u00f6glhofer"
        },
        {
            "affiliation": "Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Philip",
            "initials": "P",
            "lastname": "Cichra"
        },
        {
            "affiliation": "Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Silvia",
            "initials": "S",
            "lastname": "Lee"
        },
        {
            "affiliation": "Department of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Beate",
            "initials": "B",
            "lastname": "Eichelberger"
        },
        {
            "affiliation": "Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Patricia P",
            "initials": "PP",
            "lastname": "Wadowski"
        },
        {
            "affiliation": "Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.",
            "firstname": "G\u00fcnther",
            "initials": "G",
            "lastname": "Laufer"
        },
        {
            "affiliation": "Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Dominik",
            "initials": "D",
            "lastname": "Wiedemann"
        },
        {
            "affiliation": "Department of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Simon",
            "initials": "S",
            "lastname": "Panzer"
        },
        {
            "affiliation": "Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.",
            "firstname": "Daniel",
            "initials": "D",
            "lastname": "Zimpfer"
        },
        {
            "affiliation": "Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.\nDepartment of Internal Medicine I, Cardiology and Intensive Care Medicine, Landesklinikum Mistelbach-G\u00e4nserndorf, Mistelbach, Austria.\nInstitute of Cardiovascular Pharmacotherapy and Interventional Cardiology, Karl Landsteiner Society, St. P\u00f6lten, Austria.",
            "firstname": "Thomas",
            "initials": "T",
            "lastname": "Gremmel"
        }
    ],
    "conclusions": "\u2003Patients with blood group O had significantly lower levels of VWF and FVIII (all ",
    "copyrights": "Thieme. All rights reserved.",
    "doi": "10.1055/a-1983-0676",
    "journal": "Thrombosis and haemostasis",
    "keywords": [],
    "methods": null,
    "publication_date": "2022-11-20",
    "pubmed_id": "36402132",
    "results": "\u2003Thirty-six patients (32.4%) experienced a bleeding and 22 patients (19.8%) a thromboembolic event. In univariate analyses, patients with blood group O had numerically more bleeding complications and less thromboembolic events as compared to patients with blood group non-O (both ",
    "title": "Impact of ABO Blood Group on Thromboembolic and Bleeding Complications in Patients with Left Ventricular Assist Devices.",
    "xml": "<Element 'PubmedArticle' at 0x788502e88e50>"
}