{
    "abstract": "Tinnitus is the perception of sound without any external acoustic stimuli, affecting over 10% of the population, especially older adults. Current treatments focus on symptom management rather than a complete cure, often providing limited relief.\nTo evaluate the efficacy and safety of bimodal neuromodulation therapy for tinnitus, compared to traditional treatment methods.\nBimodal neuromodulation, which combines sound and tongue stimulation, has shown significant improvement in tinnitus symptoms. FDA-approved studies report sustained symptom reduction in over 77% of patients for up to 12\u00a0months. The most common side effect is an increase in tinnitus symptoms, similar to sound-only treatments.\nThis therapy presents a high benefit-to-risk ratio with minimal side effects, offering better clinical outcomes and patient satisfaction compared to existing treatments. Adjustments in treatment parameters can further enhance its effectiveness over time. Bimodal neuromodulation shows promise as a more effective treatment for tinnitus. Future clinical trials should replicate these positive findings, evaluate long-term effects, and compare their effectiveness to other treatment options to improve accessibility and clinical outcomes for tinnitus patients.",
    "authors": [
        {
            "affiliation": "Department of Otorhinolaryngology, Ayub Medical College, Abbottabad, Khyber Pakhtunkhwa, Pakistan.",
            "firstname": "Ali Aamir",
            "initials": "AA",
            "lastname": "Khan"
        },
        {
            "affiliation": "Department of Otorhinolaryngology, Ayub Medical College, Abbottabad, Khyber Pakhtunkhwa, Pakistan.",
            "firstname": "Hamid",
            "initials": "H",
            "lastname": "Nasim"
        },
        {
            "affiliation": "Faculty of Medicine, University of Khartoum, Khartoum, Sudan.",
            "firstname": "Gaffar Alemam A",
            "initials": "GAA",
            "lastname": "Manhal"
        },
        {
            "affiliation": "Faculty of Medicine, University of Khartoum, Khartoum, Sudan.",
            "firstname": "Khabab",
            "initials": "K",
            "lastname": "Abbasher Hussien Mohamed Ahmed"
        }
    ],
    "conclusions": "This therapy presents a high benefit-to-risk ratio with minimal side effects, offering better clinical outcomes and patient satisfaction compared to existing treatments. Adjustments in treatment parameters can further enhance its effectiveness over time. Bimodal neuromodulation shows promise as a more effective treatment for tinnitus. Future clinical trials should replicate these positive findings, evaluate long-term effects, and compare their effectiveness to other treatment options to improve accessibility and clinical outcomes for tinnitus patients.",
    "copyrights": "Copyright \u00a9 2025 The Author(s). Published by Wolters Kluwer Health, Inc.",
    "doi": "10.1097/MS9.0000000000002998",
    "journal": "Annals of medicine and surgery (2012)",
    "keywords": [
        "ENT",
        "bimodal neuromodulation therapy",
        "bimodal stimulation",
        "therapeutic potential",
        "tinnitus"
    ],
    "methods": null,
    "publication_date": "2025-04-11",
    "pubmed_id": "40213226\n23948178\n27441392\n2381186\n29621860\n35939312\n33090056\n35350720\n30915704\n845067\n33028707\n35773272",
    "results": "Bimodal neuromodulation, which combines sound and tongue stimulation, has shown significant improvement in tinnitus symptoms. FDA-approved studies report sustained symptom reduction in over 77% of patients for up to 12\u00a0months. The most common side effect is an increase in tinnitus symptoms, similar to sound-only treatments.",
    "title": "Exploring the therapeutic potential of bimodal stimulation for tinnitus.",
    "xml": "<Element 'PubmedArticle' at 0x78850582e7a0>"
}