{
    "abstract": "To investigate risk factors for infertility and recurrent cesarean scar pregnancy (CSP) after previous CSP.\nA retrospective cohort study (Canadian Task Force classification II-1).\nUniversity hospital.\nBetween January 2007 and April 2016, a total of 650 patients were included, all diagnosed with CSP and treated by high-intensity focused ultrasound (HIFU) and uterine artery embolization (UAE), followed by suction curettage under hysteroscopic guidance.\nNone.\nFollow-up of the reproductive outcomes ended in June 2017. A total of 135 of the 650 patients with CSP were involved in the study, among whom 32 became infertile, 78 had an intrauterine pregnancy, and 25 had recurrent CSP after previous CSP. Age (\u226535 years; odds ratio [OR], 4.252; p\u202f=\u202f.002), \u03b2-human chorionic gonadotropin (\u22645000 mIU/mL; OR, 3.778; p\u202f=\u202f.011), and longer duration of amenorrhea (>56 days; OR, 2.507; p\u202f=\u202f.05) were risk factors for infertility. Treatment with UAE (OR, 5.796; p\u202f=\u202f.003), more abortions (\u22654; OR, 2.851; p\u202f=\u202f.022), and being asymptomatic (OR, 4.175; p\u202f=\u202f.039) were risk factors for recurrent CSP. There was no statistically significant difference in the subsequent outcomes of pregnant women in the HIFU and UAE groups (p >.05).\nMore attention should be given to subsequent reproductive outcomes after CSP, not only for intrauterine pregnancy, but also for infertility and recurrent CSP. Early diagnosis and treatment of CSP could reduce the risk of infertility and recurrent CSP. HIFU seemed to be superior to UAE in reducing the risk of recurrent CSP. Patients with CSP should adhere to strict contraception if they do not desire more children.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynecology, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China (all authors).",
            "firstname": "Lixing",
            "initials": "L",
            "lastname": "Chen"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China (all authors).",
            "firstname": "Songshu",
            "initials": "S",
            "lastname": "Xiao"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China (all authors).",
            "firstname": "Xiaogang",
            "initials": "X",
            "lastname": "Zhu"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China (all authors).",
            "firstname": "Sili",
            "initials": "S",
            "lastname": "He"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China (all authors).. Electronic address: 1196350112@qq.com.",
            "firstname": "Min",
            "initials": "M",
            "lastname": "Xue"
        }
    ],
    "conclusions": "More attention should be given to subsequent reproductive outcomes after CSP, not only for intrauterine pregnancy, but also for infertility and recurrent CSP. Early diagnosis and treatment of CSP could reduce the risk of infertility and recurrent CSP. HIFU seemed to be superior to UAE in reducing the risk of recurrent CSP. Patients with CSP should adhere to strict contraception if they do not desire more children.",
    "copyrights": "Copyright \u00a9 2018 AAGL. Published by Elsevier Inc. All rights reserved.",
    "doi": "10.1016/j.jmig.2018.09.001",
    "journal": "Journal of minimally invasive gynecology",
    "keywords": [
        "Cesarean scar pregnancy",
        "High-intensity focused ultrasound",
        "Infertility",
        "Recurrent cesarean scar pregnancy",
        "Risk factors",
        "Uterine artery embolization"
    ],
    "methods": null,
    "publication_date": "2018-09-12",
    "pubmed_id": "30205163",
    "results": null,
    "title": "Analysis of the Reproductive Outcome of Patients with Cesarean Scar Pregnancy Treated by High-Intensity Focused Ultrasound and Uterine Artery Embolization: A Retrospective Cohort Study.",
    "xml": "<Element 'PubmedArticle' at 0x788502eb05e0>"
}