{
    "abstract": "Perioperative antibiotic prophylaxis reduces cesarean wound complications. This study investigates whether integration of standard-dose (500\u2009mg) azithromycin prophylaxis reduced wound complications in patients with class III obesity (body mass index [BMI] \u2265 40\u2009kg/m\nRetrospective cohort study of patients with class III obesity undergoing unscheduled cesarean delivery in single hospital system from January 1, 2017, to January 1, 2020. A standard dose (500\u2009mg) of azithromycin was integrated into system order sets in 2018. Medical history and postoperative wound outcomes were compared in pre- and postintegration cohorts. Wound complication was defined as composite of wound seroma, hematoma, superficial or deep infection.\nA total of 1,273 patients met inclusion criteria, 303 patients in the preorder set group, and 970 patients in the postorder set group. Demographics were similar between the pre- and postintegration cohorts, including BMI (median: 44.4\u2009kg/m\nA standard dose of azithromycin provides adequate perioperative prophylaxis in class III obese patients, decreasing rates of postcesarean wound complications and unscheduled postpartum outpatient visits.\n\u00b7 Class III obese patients undergoing unscheduled cesarean have high rates of wound complications.. \u00b7 Standard-dose azithromycin reduces risk of postcesarean wound infection in class III obese patients.. \u00b7 Standard-dose azithromycin reduces readmission, unscheduled visits in class III obese patients..",
    "authors": [
        {
            "affiliation": "Division of Maternal and Fetal Medicine, Obstetrics and Gynecology Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.",
            "firstname": "Maeve K",
            "initials": "MK",
            "lastname": "Hopkins"
        },
        {
            "affiliation": "Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.",
            "firstname": "Surabhi",
            "initials": "S",
            "lastname": "Tewari"
        },
        {
            "affiliation": "Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.",
            "firstname": "Meng",
            "initials": "M",
            "lastname": "Yao"
        },
        {
            "affiliation": "Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.",
            "firstname": "Lydia",
            "initials": "L",
            "lastname": "DeAngelo"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.",
            "firstname": "Lauren",
            "initials": "L",
            "lastname": "Buckley"
        },
        {
            "affiliation": "Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.",
            "firstname": "Victoria",
            "initials": "V",
            "lastname": "Rogness"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.",
            "firstname": "Swapna",
            "initials": "S",
            "lastname": "Kollikonda"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology and Infectious Disease, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.",
            "firstname": "Oluwatosin",
            "initials": "O",
            "lastname": "Goje"
        }
    ],
    "conclusions": "A standard dose of azithromycin provides adequate perioperative prophylaxis in class III obese patients, decreasing rates of postcesarean wound complications and unscheduled postpartum outpatient visits.",
    "copyrights": "Thieme. All rights reserved.",
    "doi": "10.1055/a-2135-7084",
    "journal": "American journal of perinatology",
    "keywords": [],
    "methods": null,
    "publication_date": "2023-07-25",
    "pubmed_id": "37487546",
    "results": "A total of 1,273 patients met inclusion criteria, 303 patients in the preorder set group, and 970 patients in the postorder set group. Demographics were similar between the pre- and postintegration cohorts, including BMI (median: 44.4\u2009kg/m",
    "title": "Standard-Dose Azithromycin in Class III Obese Patients Undergoing Unscheduled Cesarean Delivery.",
    "xml": "<Element 'PubmedArticle' at 0x788504691760>"
}