{
    "abstract": "Placental abruption (PA) is a major obstetric complication associated with worse maternal and neonatal outcomes. Though ultrasound findings may support the diagnosis of PA, the association of such findings to the severity of PA and maternal and neonatal outcomes is not yet clear. We aimed to assess the maternal and neonatal outcomes of PA cases with vs. without related sonographic findings.\nIn this retrospective cohort study, all deliveries complicated by PA between 2009 and 2022 were included. Placental histopathology, obstetric, and neonatal outcomes were compared between cases of PA with vs. without supporting sonographic findings. A composite of severe neonatal morbidity was compared between the groups, including \u22651 of the following: seizures, intraventricular hemorrhage, hypoxic-ischemic encephalopathy, periventricular leukomalacia, respiratory-distress syndrome, sepsis, anemia, blood transfusion or death.\nOf the 420 cases with PA eligible for the study, 50 patients (12\u00a0%) were in the PA with sonographic features group and 370 (88\u00a0%) were in the PA without sonographic features group. The PA with sonographic features group was characterized by significantly higher rates of prematurity (p\u00a0<\u00a00.001), severe composite adverse neonatal outcome (p\u00a0<\u00a00.01), and a composite maternal vascular malperfusion lesions in placental histopathology (p\u00a0=\u00a00.001) In multivariable regression analyses, preterm birth was independently associated with the presence of sonographic features (aOR\u00a0=\u00a08.79, 95\u00a0% CI 2.41-31.93, p\u00a0<\u00a00.001).\nPA with supporting sonographic features is associated with higher rates of adverse obstetric and neonatal outcomes and placental lesions. These findings emphasize the importance of sonographic evaluation for every case of PA before deciding upon management.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel. Electronic address: liatmo@wmc.gov.il.",
            "firstname": "Liat",
            "initials": "L",
            "lastname": "Mor"
        },
        {
            "affiliation": "Faculty of Medicine, Tel Aviv University, Israel.",
            "firstname": "Naama",
            "initials": "N",
            "lastname": "Erteschik"
        },
        {
            "affiliation": "Faculty of Medicine, Tel Aviv University, Israel.",
            "firstname": "Erika",
            "initials": "E",
            "lastname": "Gandelsman"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel.",
            "firstname": "Anna",
            "initials": "A",
            "lastname": "Vartkova"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel.",
            "firstname": "Ilia",
            "initials": "I",
            "lastname": "Kleiner"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel.",
            "firstname": "Giulia",
            "initials": "G",
            "lastname": "Barda"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel.",
            "firstname": "Liat",
            "initials": "L",
            "lastname": "Gindes"
        },
        {
            "affiliation": "Department of Pathology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel.",
            "firstname": "Letizia",
            "initials": "L",
            "lastname": "Schreiber"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel.",
            "firstname": "Eran",
            "initials": "E",
            "lastname": "Weiner"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Halochamim 62, Holon, Israel.",
            "firstname": "Noa",
            "initials": "N",
            "lastname": "Gonen"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2024 Elsevier Ltd. All rights reserved.",
    "doi": "10.1016/j.placenta.2024.08.017",
    "journal": "Placenta",
    "keywords": [
        "Maternal outcomes",
        "Neonatal outcomes",
        "Placental abruption",
        "Sonographic findings"
    ],
    "methods": null,
    "publication_date": "2024-09-03",
    "pubmed_id": "39222560",
    "results": "Of the 420 cases with PA eligible for the study, 50 patients (12\u00a0%) were in the PA with sonographic features group and 370 (88\u00a0%) were in the PA without sonographic features group. The PA with sonographic features group was characterized by significantly higher rates of prematurity (p\u00a0<\u00a00.001), severe composite adverse neonatal outcome (p\u00a0<\u00a00.01), and a composite maternal vascular malperfusion lesions in placental histopathology (p\u00a0=\u00a00.001) In multivariable regression analyses, preterm birth was independently associated with the presence of sonographic features (aOR\u00a0=\u00a08.79, 95\u00a0% CI 2.41-31.93, p\u00a0<\u00a00.001).",
    "title": "Obstetric and neonatal outcomes in pregnancies complicated by placental abruption with vs. without supporting sonographic findings- A retrospective cohort study.",
    "xml": "<Element 'PubmedArticle' at 0x788503ae99e0>"
}