{
    "abstract": "The aim of this study was to construct a low-cost, anthropomorphic, and 3D-printed pelvis phantom and evaluate the feasibility of its use to perform 3D dosimetry with commercially available bead thermoluminescent dosimeters (TLDs).\nA novel anthropomorphic female phantom was developed with all relevant pelvic organs to position the bead TLDs. Organs were 3D-printed using acrylonitrile butadiene styrene. Phantom components were confirmed to have mass density and computed tomography (CT) numbers similar to relevant tissues. To find out clinically required spatial resolution of beads to cause no perturbation effect, TLDs were positioned with 2.5, 5, and 7.5 mm spacing on the surface of syringe. After taking a CT scan and creating a 4-field conformal radiotherapy plan, 3 dose planes were extracted from the treatment planning system (TPS) at different depths. By using a 2D-gamma analysis, the TPS reports were compared with and without the presence of beads. Moreover, the bead TLDs were placed on the organs' surfaces of the pelvis phantom and exposed to high-dose-rate (HDR) \n3D-printed phantom organs agreed well with body tissues regarding both their design and radiation properties. Furthermore, the 2D-gamma analysis on the syringe showed more than 99% points passed 3%- and 3-mm criteria at different depths. By calculating the integral dose of DSHs, the percentage differences were -1.5%, 2%, 5%, and 10% for uterus, rectum, bladder, and sigmoid, respectively. Also, combined standard uncertainty was estimated as 3.5% (\nA customized pelvis phantom was successfully built and assessed to confirm properties similar to body tissues. Additionally, no significant perturbation effect with different bead resolutions was presented by the external TPS, with 0.1 mm dose grid resolution.",
    "authors": [
        {
            "affiliation": "Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.\nDepartment of Physics, University of Surrey, Guildford, United Kingdom.",
            "firstname": "Somayyeh",
            "initials": "S",
            "lastname": "Babaloui"
        },
        {
            "affiliation": "Department of Physics, University of Surrey, Guildford, United Kingdom.\nMedical Physics Department, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.",
            "firstname": "Shakardokht",
            "initials": "S",
            "lastname": "Jafari"
        },
        {
            "affiliation": "Medical Physics Department, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.",
            "firstname": "Wojciech",
            "initials": "W",
            "lastname": "Polak"
        },
        {
            "affiliation": "Biomedical Engineering and Medical Physics Department, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.",
            "firstname": "Mahdi",
            "initials": "M",
            "lastname": "Ghorbani"
        },
        {
            "affiliation": "Department of Physics, University of Surrey, Guildford, United Kingdom.",
            "firstname": "Michael Wj",
            "initials": "MW",
            "lastname": "Hubbard"
        },
        {
            "affiliation": "Department of Physics, University of Surrey, Guildford, United Kingdom.\nSchool of Physical Sciences, The Open University, Milton Keynes, United Kingdom.",
            "firstname": "Annika",
            "initials": "A",
            "lastname": "Lohstroh"
        },
        {
            "affiliation": "Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.",
            "firstname": "Alireza",
            "initials": "A",
            "lastname": "Shirazi"
        },
        {
            "affiliation": "Department of Physics, University of Surrey, Guildford, United Kingdom.\nRadiation Oncology Research Centre (RORC), Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.",
            "firstname": "Ramin",
            "initials": "R",
            "lastname": "Jaberi"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2020 Termedia.",
    "doi": "10.5114/jcb.2020.100380",
    "journal": "Journal of contemporary brachytherapy",
    "keywords": [
        "3D dosimetry",
        "anthropomorphic phantom",
        "radiotherapy",
        "silica bead TLDs"
    ],
    "methods": null,
    "publication_date": "2020-12-11",
    "pubmed_id": "33299436\n24529964\n21978061\n28727787\n11872306\n23835381\n29102154\n28857407\n25207965\n12065106\n26077382\n27587055\n26258442\n29173920\n22770690\n9608475\n9155080\n8823277\n23822434\n11173143\n23475338\n24631144\n19767117",
    "results": "3D-printed phantom organs agreed well with body tissues regarding both their design and radiation properties. Furthermore, the 2D-gamma analysis on the syringe showed more than 99% points passed 3%- and 3-mm criteria at different depths. By calculating the integral dose of DSHs, the percentage differences were -1.5%, 2%, 5%, and 10% for uterus, rectum, bladder, and sigmoid, respectively. Also, combined standard uncertainty was estimated as 3.5% (",
    "title": "Development of a novel and low-cost anthropomorphic pelvis phantom for 3D dosimetry in radiotherapy.",
    "xml": "<Element 'PubmedArticle' at 0x788505ab4ea0>"
}