{
    "abstract": "Extracorporeal membrane oxygenation (ECMO) is a type of extracorporeal circulation used to divert blood from and deliver blood to peripheral blood vessels. Recently, the use of ECMO has been reported in various non-transplant surgeries. Particularly in tracheal surgeries, ECMO provides an unobstructed surgical field and enables safe induction of general anesthesia in difficult intubation cases. Here, we report on 10 cases of thoracic surgery in which ECMO was employed at our institution.\nThese 10 cases comprise 4 tracheal cancer surgeries, 2 lung cancer surgeries, and 1 case each of surgery for thyroid cancer, mediastinal cancer, tracheomalacia, and tracheobronchial injury. Veno-venous (VV)-ECMO is most often selected, but veno-arterial (VA)-ECMO is chosen when recirculation with VV-ECMO is unacceptable, when pulmonary artery bleeding needs to be controlled, or when cardiac support is necessary. Among the 10 presented cases, VV-ECMO was used in 8, while VA-ECMO was employed in 2. Three of these cases involved ECMO bailout due to dyspnea caused by airway stenosis. Six of the patients did not receive heparin maintenance. Of those, 1 was maintained on nafamostat mesilate, 2 were maintained on nafamostat mesilate after receiving a single dose of heparin, and 3 received only a single dose of heparin. In none of those cases did ECMO fail to maintain flow due to thrombus formation. A postoperative hemothorax occurred as one of the ECMO-related complications in Case 4. There were no perioperative cardiopulmonary complications, in-hospital deaths, or deaths within 30 days after surgery. One patient died from metastatic recurrence of non-small cell lung cancer 5 months after surgery, another from progression of disease in mediastinal anaplastic cancer 4 months after surgery, and the 3rd from upper gastrointestinal bleeding 2 years after surgery. The other 7 patients remain alive.\nECMO is useful in tracheal surgery and in cases where intubation is difficult or dangerous, because it facilitates safe and accurate surgery. We also believe that individualized anticoagulant strategies can be safely implemented.",
    "authors": [
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Yuzu",
            "initials": "Y",
            "lastname": "Harata"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Kazuhiro",
            "initials": "K",
            "lastname": "Imai"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Shinogu",
            "initials": "S",
            "lastname": "Takashima"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Shoji",
            "initials": "S",
            "lastname": "Kuriyama"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Hidenobu",
            "initials": "H",
            "lastname": "Iwai"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Haruka",
            "initials": "H",
            "lastname": "Suzuki"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Ryo",
            "initials": "R",
            "lastname": "Demura"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Sumire",
            "initials": "S",
            "lastname": "Shibano"
        },
        {
            "affiliation": "Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita, Akita, Japan.",
            "firstname": "Yoshihiro",
            "initials": "Y",
            "lastname": "Minamiya"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025 The Author(s). Published by Japan Surgical Society.",
    "doi": "10.70352/scrj.cr.24-0004",
    "journal": "Surgical case reports",
    "keywords": [
        "airway obstruction",
        "anticoagulation",
        "extracorporeal membrane oxygenation",
        "thoracic surgery"
    ],
    "methods": null,
    "publication_date": "2025-03-24",
    "pubmed_id": "40124321\n33666866\n32912280\n33536388\n37601529\n38738217\n38505033\n28072940\n24651227\n35080509\n34921625\n35761333\n22926653\n27456703\n33965970\n25423117\n27660904\n37548506\n36647480\n31761653\n27449451\n33624260\n24210621\n28342510\n26728787\n35850387\n38643128\n37316557\n39161257\n26109311\n27890016\n39256830",
    "results": null,
    "title": "Extracorporeal Membrane Oxygenation-Assisted Thoracic Surgery: A Series of 10 Cases.",
    "xml": "<Element 'PubmedArticle' at 0x788503a566b0>"
}