{
    "abstract": "While the majority of venous thromboembolism (VTE) during pregnancy events resolve with anticoagulation, long-term complications may occur including (1) postthrombotic syndrome and (2) chronic pulmonary embolism. The objective of this study was to determine risk of these two complications.\nA retrospective cohort study using the MarketScan databases was performed on deliveries from 2008 to 2014. We identified women aged 15 to 54 years diagnosed with acute VTE during pregnancy, the delivery hospitalization, or \u226460 days postpartum who received at least one prescription postpartum for anticoagulants. Risks of (1) chronic PE and (2) postthrombotic syndrome were evaluated for women at 6, 12, 24, and 60 months after delivery hospitalization through 2017 via the International Classification of Diseases, 9th/10th Revision, Clinical Modification codes.\nOf 4,267 of 4,128,900 pregnancies complicated by VTE, the majority had DVT alone (61.8%, \nIn comparison to the general population, the risk of postthrombotic syndrome was lower. In comparison, the risk of chronic PE was similar to the estimates in the general population at comparable time points after PE events. For women with obstetric PE, it may be appropriate to be vigilant for findings and symptoms associated with chronic PE.\n\u00b7 Risk of postthrombotic syndrome after obstetric deep vein thrombosis is low.. \u00b7 Risk of chronic pulmonary embolism may approximate that in the general population.. \u00b7 Overall risk of chronic complications after obstetric VTE was relatively low..",
    "authors": [
        {
            "affiliation": "Pharmacy Department, Rotunda Hospital, Dublin, Ireland.\nDivision of Population Health Sciences, Royal College of Surgeons, Dublin, Ireland.",
            "firstname": "Fergal",
            "initials": "F",
            "lastname": "O'Shaugnessy"
        },
        {
            "affiliation": "Cedars-Sinai Medical Center, Los Angeles, California.",
            "firstname": "Shravya",
            "initials": "S",
            "lastname": "Govindappagari"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York.",
            "firstname": "Yongmei",
            "initials": "Y",
            "lastname": "Huang"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York.",
            "firstname": "Sbaa K",
            "initials": "SK",
            "lastname": "Syeda"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York.",
            "firstname": "Mary E",
            "initials": "ME",
            "lastname": "D'Alton"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York.",
            "firstname": "Jason D",
            "initials": "JD",
            "lastname": "Wright"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York.",
            "firstname": "Alexander M",
            "initials": "AM",
            "lastname": "Friedman"
        }
    ],
    "conclusions": "In comparison to the general population, the risk of postthrombotic syndrome was lower. In comparison, the risk of chronic PE was similar to the estimates in the general population at comparable time points after PE events. For women with obstetric PE, it may be appropriate to be vigilant for findings and symptoms associated with chronic PE.",
    "copyrights": "Thieme. All rights reserved.",
    "doi": "10.1055/s-0041-1739471",
    "journal": "American journal of perinatology",
    "keywords": [],
    "methods": null,
    "publication_date": "2021-11-23",
    "pubmed_id": "34808685",
    "results": "Of 4,267 of 4,128,900 pregnancies complicated by VTE, the majority had DVT alone (61.8%, ",
    "title": "Postthrombotic Syndrome and Chronic Pulmonary Embolism after Obstetric Venous Thromboembolism.",
    "xml": "<Element 'PubmedArticle' at 0x788502d44090>"
}