{
    "abstract": "Volumetric capnography is an alternative method of measuring expired carbon dioxide partial pressure (P(eCO2)) and physiologic dead-space-to-tidal-volume ratio (V(D)/V(T)) during mechanical ventilation. In this method, P(eCO2) is measured at the Y-adapter of the ventilator circuit, thus eliminating the effects of compression volume contamination and the need to apply a correction factor. We investigated the accuracy of volumetric capnography in measuring V(D)/V(T), compared to both uncorrected and corrected measurements, using a metabolic monitor in patients with acute respiratory distress syndrome (ARDS).\nThere were 90 measurements of V(D)/V(T) made in 23 patients with ARDS. The P(eCO2) was measured during a 5-min expired-gas collection period with a Delta-trac metabolic monitor, and was corrected for compression volume contamination using a standard formula. Simultaneous measurements of P(eCO2) and V(D)/V(T) were obtained using volumetric capnography.\nV(D)/V(T) measured by volumetric capnography was strongly correlated with both the uncorrected (r2 = 0.93, p < 0.0001) and corrected (r2 = 0.89, p < 0.0001) measurements of V(D)/V(T) made using the metabolic monitor technique. Measurements of V(D)/V(T) made with volumetric capnography had a bias of 0.02 and a precision of 0.05 when compared to the V(D)/V(T) corrected for estimated compression volume contamination.\nVolumetric capnography measurements of V(D)/V(T) in mechanically-ventilated patients with ARDS are as accurate as those obtained by metabolic monitor technique. .",
    "authors": [
        {
            "affiliation": "Cardiovascular Research Institute, University of California, San Francisco, CA, USA. richkallet@earthlink.net",
            "firstname": "Richard H",
            "initials": "RH",
            "lastname": "Kallet"
        },
        {
            "affiliation": null,
            "firstname": "Brian M",
            "initials": "BM",
            "lastname": "Daniel"
        },
        {
            "affiliation": null,
            "firstname": "Oscar",
            "initials": "O",
            "lastname": "Garcia"
        },
        {
            "affiliation": null,
            "firstname": "Michael A",
            "initials": "MA",
            "lastname": "Matthay"
        }
    ],
    "conclusions": "Volumetric capnography measurements of V(D)/V(T) in mechanically-ventilated patients with ARDS are as accurate as those obtained by metabolic monitor technique. .",
    "copyrights": null,
    "doi": null,
    "journal": "Respiratory care",
    "keywords": [],
    "methods": null,
    "publication_date": "2005-04-06",
    "pubmed_id": "15807908",
    "results": "V(D)/V(T) measured by volumetric capnography was strongly correlated with both the uncorrected (r2 = 0.93, p < 0.0001) and corrected (r2 = 0.89, p < 0.0001) measurements of V(D)/V(T) made using the metabolic monitor technique. Measurements of V(D)/V(T) made with volumetric capnography had a bias of 0.02 and a precision of 0.05 when compared to the V(D)/V(T) corrected for estimated compression volume contamination.",
    "title": "Accuracy of physiologic dead space measurements in patients with acute respiratory distress syndrome using volumetric capnography: comparison with the metabolic monitor method.",
    "xml": "<Element 'PubmedArticle' at 0x788503a57a10>"
}