{
    "abstract": "To investigate whether perineal wound complications in the first birth, alone or in conjunction with obstetric anal sphincter injury (OASI), is associated with an increased risk of OASI in the second birth.\nNationwide population-based cohort study.\nSweden.\nWomen (n\u2009=\u2009411\u2009317) with first and second singleton vaginal births in Sweden, 2001-2019.\nData on diagnostic codes and surgical procedures were retrieved from the Swedish Medical Birth Register and the Swedish Patient Register. A perineal wound complication was defined as wound infection, dehiscence or perineal haematoma within 2\u2009months of childbirth.\nAssociations between wound complications in the first birth and OASI in the second birth were investigated with logistic regression and presented as adjusted odds ratios (aORs) with 95% confidence intervals (95%\u2009CIs).\nIn total, 2619 (0.6%) women had a wound complication in the first birth, and 5318 (1.3%) had an OASI in the second birth. Women with a wound complication but no OASI in the first birth had more than doubled odds of OASI in the second birth (aOR\u20092.73, 95%\u2009CI 2.11-3.53). Women with OASI and a wound complication in the first birth had almost tenfold odds (aOR\u20099.97, 95%\u2009CI 6.53-15.24) of recurrent OASI.\nPerineal wound complication in the first birth increases the likelihood of OASI in a subsequent birth.",
    "authors": [
        {
            "affiliation": "Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.\nCentre for Clinical Research, Uppsala University, Falun, Sweden.",
            "firstname": "Agnes",
            "initials": "A",
            "lastname": "Rygaard"
        },
        {
            "affiliation": "Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.",
            "firstname": "Maria",
            "initials": "M",
            "lastname": "Jonsson"
        },
        {
            "affiliation": "Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.",
            "firstname": "Anna-Karin",
            "initials": "AK",
            "lastname": "Wikstr\u00f6m"
        },
        {
            "affiliation": "Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.\nDepartment of Women's Health, Danderyd Hospital, Stockholm, Sweden.",
            "firstname": "Sophia",
            "initials": "S",
            "lastname": "Brismar-Wendel"
        },
        {
            "affiliation": "Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.\nCentre for Clinical Research, Uppsala University, Falun, Sweden.",
            "firstname": "Susanne",
            "initials": "S",
            "lastname": "Hesselman"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2024 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd.",
    "doi": "10.1111/1471-0528.17830",
    "journal": "BJOG : an international journal of obstetrics and gynaecology",
    "keywords": [
        "OASI",
        "obstetric anal sphincter injury",
        "perineal wound complication"
    ],
    "methods": null,
    "publication_date": "2024-04-17",
    "pubmed_id": "38628047",
    "results": "In total, 2619 (0.6%) women had a wound complication in the first birth, and 5318 (1.3%) had an OASI in the second birth. Women with a wound complication but no OASI in the first birth had more than doubled odds of OASI in the second birth (aOR\u20092.73, 95%\u2009CI 2.11-3.53). Women with OASI and a wound complication in the first birth had almost tenfold odds (aOR\u20099.97, 95%\u2009CI 6.53-15.24) of recurrent OASI.",
    "title": "Obstetric anal sphincter injury in the second birth after perineal wound complication in the first birth: A nationwide register cohort study.",
    "xml": "<Element 'PubmedArticle' at 0x78850396c6d0>"
}