{
    "abstract": "Pulmonary arterial hypertension (PAH) is a rare vasculopathy, with high morbidity and mortality. The sensitivity of the current european society of cardiology/european respiratory society (ESC/ERS) risk assessment strategy may be improved by the addition of biomarkers related to PAH pathophysiology. Such plasma-borne biomarkers may also reduce time to diagnosis, if used as diagnostic tools in patients with unclear dyspnea, and in guiding treatment decisions. Plasma levels of proteins related to tumor necrosis factor (TNF), inflammation, and immunomodulation were analyzed with proximity extension assays in patients with PAH (",
    "authors": [
        {
            "affiliation": "Department of Clinical Sciences Lund, Cardiology Faculty of Medicine, Lund University Lund Sweden.\nThe Hemodynamic Lab, The Section for Heart Failure and Valvular Disease VO Heart and Lung Medicine, Sk\u00e5ne University Hospital Lund Sweden.",
            "firstname": "Mattias",
            "initials": "M",
            "lastname": "Arvidsson"
        },
        {
            "affiliation": "Department of Clinical Sciences Lund, Cardiology Faculty of Medicine, Lund University Lund Sweden.\nThe Hemodynamic Lab, The Section for Heart Failure and Valvular Disease VO Heart and Lung Medicine, Sk\u00e5ne University Hospital Lund Sweden.",
            "firstname": "Abdulla",
            "initials": "A",
            "lastname": "Ahmed"
        },
        {
            "affiliation": "Department of Clinical Sciences Lund, Cardiology Faculty of Medicine, Lund University Lund Sweden.\nThe Hemodynamic Lab, The Section for Heart Failure and Valvular Disease VO Heart and Lung Medicine, Sk\u00e5ne University Hospital Lund Sweden.",
            "firstname": "Joanna",
            "initials": "J",
            "lastname": "S\u00e4leby"
        },
        {
            "affiliation": "Department of Clinical Sciences Lund, Cardiology Faculty of Medicine, Lund University Lund Sweden.\nThe Hemodynamic Lab, The Section for Heart Failure and Valvular Disease VO Heart and Lung Medicine, Sk\u00e5ne University Hospital Lund Sweden.",
            "firstname": "Salaheldin",
            "initials": "S",
            "lastname": "Ahmed"
        },
        {
            "affiliation": "Department of Clinical Sciences Lund, Rheumatology Faculty of Medicine, Lund University Lund Sweden.\nDepartment of Rheumatology Sk\u00e5ne University Hospital Lund Sweden.",
            "firstname": "Roger",
            "initials": "R",
            "lastname": "Hesselstrand"
        },
        {
            "affiliation": "Department of Clinical Sciences Lund, Cardiology Faculty of Medicine, Lund University Lund Sweden.\nThe Hemodynamic Lab, The Section for Heart Failure and Valvular Disease VO Heart and Lung Medicine, Sk\u00e5ne University Hospital Lund Sweden.",
            "firstname": "G\u00f6ran",
            "initials": "G",
            "lastname": "R\u00e5degran"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2023 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute.",
    "doi": "10.1002/pul2.12269\n10.1111/resp.13768\n10.7326/0003-4819-107-2-216\n10.1016/S0733-8627(05)70054-7\n10.1093/eurheartj/ehv317\n10.1093/eurheartj/ehac237\n10.1016/j.chest.2019.02.004\n10.1016/j.chest.2020.08.2069\n10.1016/j.healun.2020.03.026\n10.1183/13993003.01887-2018\n10.1038/ncomms14079\n10.1084/jem.20112716\n10.1038/s41467-019-13139-9\n10.1183/09031936.00139009\n10.1183/13993003.01032-2015\n10.1093/eurheartj/ehs104\n10.1371/journal.pone.0095192\n10.1002/ehf2.13184\n10.1093/eurheartj/ehx257\n10.1177/2045894019895414\n10.1183/13993003.01904-2018\n10.1016/1074-7613(95)90057-8\n10.1074/jbc.273.23.14363\n10.1016/j.canlet.2010.11.001\n10.1007/s10637-017-0536-y\n10.1038/nrc.2017.28\n10.1016/j.vph.2014.10.002\n10.1161/CIRCRESAHA.118.313911\n10.3390/ijms19092730\n10.1016/j.ijcard.2012.10.026\n10.1080/14017431.2016.1185532",
    "journal": "Pulmonary circulation",
    "keywords": [
        "TNF\u2010signaling",
        "biomarkers",
        "immunomodulation",
        "inflammation",
        "pulmonary hypertension"
    ],
    "methods": null,
    "publication_date": "2023-07-28",
    "pubmed_id": "37502145\n31997504\n3605900\n10101348\n26320113\n36017548\n30772387\n32882243\n32336606\n30545970\n28084316\n23071256\n31729368\n19749199\n26318161\n22611136\n24755770\n33403810\n28575277\n31908766\n30545972\n8777713\n9603945\n21220186\n29134432\n28536452\n25446166\n30661465\n30213070\n23164592\n27146648",
    "results": null,
    "title": "Plasma TRAIL and ANXA1 in diagnosis and prognostication of pulmonary arterial hypertension.",
    "xml": "<Element 'PubmedArticle' at 0x788503dbb100>"
}