{
    "abstract": "To introduce an alternative surgical technique of laparoscopic inguinal ligament suspension (LILS) with uterine preservation and evaluate its efficacy and safety for patients with severe pelvic organ prolapse (POP).\nBetween June 2014 and December 2015, 35 patients with symptomatic stage III or IV were treated by LILS with uterine preservation. The perioperative parameters including surgical time, blood loss, hospital stay and complications were recorded. The anatomical cure rate was evaluated according to the Pelvic Organ Prolapse Questionnaire (POP-Q) assessment. The anatomical points were analyzed by dynamic Magnetic Resonance Imaging (MRI). Validated questionnaire of the Pelvic Floor Distress Inventory (PFDI-20), the Pelvic Floor Impact Questionnaire (PFIQ-7) and the Pelvic organ prolapse urinary Incontinence Sexual Questionnaire (PISQ-12) were recorded to evaluate the symptom severity, quality of life and sexual activity.\nThe mean surgical time was 163.8\u202f\u00b1\u202f42.3\u202fmin (range: 120-280\u202fmin), the mean estimated blood loss was 48.6\u202f\u00b1\u202f60.5\u202fml (range: 10-200\u202fml), and the mean hospital stay was 5 days (range: 3-7 days). No intra-operative complications were encountered. The anatomical success rate at postoperative 6-month and 12-month was 97.1% and 94.3%, respectively. The postoperative anatomical points on straining showed a significant improvement on dynamic MRI as compared to baselines. The symptom severity, quality of life and sexual activity also presented significant improvement both 6-month and 12-month after surgery. After a minimal 12 months follow-up, no postoperative complications occurred and the recurrence prolapse were low.\nLILS with uterine preservation is a feasible, effective and safe surgical alternative in the treatment of POP for patients who desire to reserve uterus. Longer follow-up data from larger studies are required to confirm the benefits of LILS with uterine preservation as a minimally invasive surgical approach.",
    "authors": [
        {
            "affiliation": "Department of Gynaecology and Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.",
            "firstname": "Chunbo",
            "initials": "C",
            "lastname": "Li"
        },
        {
            "affiliation": "Department of Gynaecology and Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.",
            "firstname": "Huimin",
            "initials": "H",
            "lastname": "Shu"
        },
        {
            "affiliation": "Department of Gynaecology and Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address: daizhiyuan@51mch.com.",
            "firstname": "Zhiyuan",
            "initials": "Z",
            "lastname": "Dai"
        }
    ],
    "conclusions": "LILS with uterine preservation is a feasible, effective and safe surgical alternative in the treatment of POP for patients who desire to reserve uterus. Longer follow-up data from larger studies are required to confirm the benefits of LILS with uterine preservation as a minimally invasive surgical approach.",
    "copyrights": "Copyright \u00a9 2018 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.",
    "doi": "10.1016/j.ijsu.2018.04.020",
    "journal": "International journal of surgery (London, England)",
    "keywords": [
        "Laparoscopic inguinal ligament suspension",
        "Minimally invasive surgery",
        "Pelvic organ prolapse",
        "Uterus-preserving technique"
    ],
    "methods": null,
    "publication_date": "2018-04-21",
    "pubmed_id": "29673691",
    "results": "The mean surgical time was 163.8\u202f\u00b1\u202f42.3\u202fmin (range: 120-280\u202fmin), the mean estimated blood loss was 48.6\u202f\u00b1\u202f60.5\u202fml (range: 10-200\u202fml), and the mean hospital stay was 5 days (range: 3-7 days). No intra-operative complications were encountered. The anatomical success rate at postoperative 6-month and 12-month was 97.1% and 94.3%, respectively. The postoperative anatomical points on straining showed a significant improvement on dynamic MRI as compared to baselines. The symptom severity, quality of life and sexual activity also presented significant improvement both 6-month and 12-month after surgery. After a minimal 12 months follow-up, no postoperative complications occurred and the recurrence prolapse were low.",
    "title": "Laparoscopic inguinal ligament suspension with uterine preservation for pelvic organ prolapse: A retrospective cohort study.",
    "xml": "<Element 'PubmedArticle' at 0x7885045e4680>"
}