{
    "abstract": "Low-intensity pulsed ultrasound (LIPUS) and low-level laser therapy (LLLT) are proposed adjunctive therapies to enhance healing after dental implant surgery. However, direct comparisons of their effects on peri-implant marginal bone preservation and soft tissue healing remain limited. This randomized controlled trial aimed to compare the effectiveness of LIPUS and LLLT on peri-implant marginal bone preservation, soft tissue healing, pain levels, and oral health-related quality of life following dental implant placement.\nThis single-blind, randomized controlled trial included 63 patients undergoing maxillary or mandibular implant placement, randomly allocated to LIPUS (n\u2009=\u200921), LLLT (n\u2009=\u200921), or control (n\u2009=\u200921) groups. LIPUS was applied twice weekly for 4 weeks, while LLLT was administered in 4 sessions over 2 weeks post-implant. Marginal bone loss (MBL) and OHRQoL (OHIP-14) were assessed at baseline, 6, and 12 weeks. Soft tissue healing (Landry Healing Index) and pain (VAS) were evaluated at baseline, 7-, 14-, 21-, and 30-days post-implant.\nLIPUS significantly reduced marginal bone loss at 6 weeks and 3 months post-implant compared to LLLT and control groups (p\u2009<\u20090.05). LLLT demonstrated superior soft tissue healing at 7-, 14-, 21-, and 30-days post-implant (p\u2009<\u20090.05). Both interventions significantly decreased pain intensity and improved OHRQoL at various time points compared to the control group (p\u2009<\u20090.05).\nLIPUS and LLLT significantly enhance peri-implant marginal bone preservation, soft tissue healing, pain management, and OHRQoL in dental implant patients compared to standard care. LIPUS was more effective for peri-implant marginal bone preservation, while LLLT excelled in soft tissue healing.\nThis study was registered at ClinicalTrials.gov (NCT05938868) on July 11, 2023.",
    "authors": [
        {
            "affiliation": "Department of Physical Therapy for surgery & burn, Faculty of Physical Therapy, Al-Hayah University in Cairo, Universities & Schools hub, New Cairo 3, 5th Settlement, Cairo, Egypt. esraa.sabry@ahuc.edu.eg.",
            "firstname": "Esraa S",
            "initials": "ES",
            "lastname": "Mahmoud"
        },
        {
            "affiliation": "Department of Physical Therapy for surgery, Faculty of Physical Therapy, Cairo University, Cairo, Egypt.",
            "firstname": "Amal M Abd",
            "initials": "AMA",
            "lastname": "El-Baky"
        },
        {
            "affiliation": "Faculty of Dentistry, Badr University, Cairo, Egypt.",
            "firstname": "Osama M",
            "initials": "OM",
            "lastname": "Gouda"
        },
        {
            "affiliation": "Department of Physical Therapy for surgery, Faculty of Physical Therapy, Cairo University, Cairo, Egypt.",
            "firstname": "Hussein G",
            "initials": "HG",
            "lastname": "Hussein"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025. The Author(s).",
    "doi": "10.1186/s13005-025-00502-z",
    "journal": "Head & face medicine",
    "keywords": [
        "Dental implants",
        "Low-intensity pulsed ultrasound",
        "Low-level laser therapy",
        "Oral health-related quality of life",
        "Osseointegration",
        "Pain",
        "Soft tissue healing"
    ],
    "methods": null,
    "publication_date": "2025-04-24",
    "pubmed_id": "40269949\n32122215\n24947899\n36098000\n33954187\n29079267\n30075090\n30904559\n24612346\n23527335\n35747499\n33921531\n37366669\n21459497\n39098624\n24507669\n20505115\n11315994\n23062370\n28532896\n8288661\n28748217\n16144476\n17968491\n22404559\n32662840\n11323066\n25778741\n32329198\n33728493\n36836025\n24609605\n32188053\n33063461\n28144432\n31613949\n23360688\n38923709\n31058617\n20303052\n9332805\n31410893\n32777837\n24383987\n35831919\n11354213\n37999024\n28497937\n34945337\n33818526\n36541106\n39407769\n23281261\n32145206\n37094757\n35409826\n30824993\n23341848\n28228381\n25060830",
    "results": "LIPUS significantly reduced marginal bone loss at 6 weeks and 3 months post-implant compared to LLLT and control groups (p\u2009<\u20090.05). LLLT demonstrated superior soft tissue healing at 7-, 14-, 21-, and 30-days post-implant (p\u2009<\u20090.05). Both interventions significantly decreased pain intensity and improved OHRQoL at various time points compared to the control group (p\u2009<\u20090.05).",
    "title": "Low intensity pulsed ultrasound versus low-level laser therapy on peri-implant marginal bone preservation and soft tissue healing following dental implant surgery: a randomized controlled trial.",
    "xml": "<Element 'PubmedArticle' at 0x7885037ade40>"
}