{
    "abstract": "The rates of labor induction and cesarean delivery is rising worldwide. With the confluence of these trends, the labor induction rate in trials of labor after cesarean can be as high as 27-32.7%. Induction of labor after one previous cesarean (IOLAC) is a high-risk procedure mainly due to the higher risk of uterine rupture. Nevertheless, the American College of Obstetricians and Gynecologists considers IOLAC as an option in motivated and informed women in the appropriate care setting. We sought to identify predictors of a composite of maternal and newborn adverse outcomes following IOLAC.\nThe electronic medical records of women who delivered between January 2018 to September 2022 in a Malaysian university hospital were screened to identify cases of IOLAC. A case is classified as a composite adverse outcome if at least one of these 11 adverse outcomes of delivery blood loss\u2009\u2265\u20091000\u00a0ml, uterine scar complications, cord prolapse or presentation, placenta abruption, maternal fever (\u2265\u200938 \nElectronic medical records of 19,064 women were screened. 819 IOLAC cases and 98 cases with composite adverse outcomes were identified. Maternal height, ethnicity, previous vaginal delivery, indication of previous cesarean, indication for IOLAC, and method of IOLAC had p\u2009<\u20090.10 on bivariate analysis and were incorporated into a multivariable binary logistic regression analysis. After adjustment, only maternal height and IOLAC by vaginal dinoprostone compared to Foley balloon remained significant at p\u2009<\u20090.05. Post hoc adjusted analysis that included all unplanned cesarean as an added qualifier for composite adverse outcome showed higher body mass index, short stature (<\u2009157\u00a0cm), not of Chinese ethnicity, no prior vaginal delivery, prior cesarean indicated by labor dystocia, and less favorable Bishop score (<\u20096) were independent predictors of the expanded composite adverse outcome.\nShorter women and IOLAC by vaginal dinoprostone compared to Foley balloon were independently predictive of composite of adverse outcome.\nShorter stature and dinoprostone labor induction are independent predictors of a composite maternal-newborn adverse outcome excluding unplanned cesarean delivery.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynecology, Faculty of Medicine, University Malaya, Jalan Profesor Diraja Ungku Aziz, Kuala Lumpur, 50603, Malaysia.\nDeparment of Obstetrics and Gynecology, North Middlesex University Hospital NHS Trust, Sterling Way, London, N18 1QX, UK.",
            "firstname": "Sze Ping",
            "initials": "SP",
            "lastname": "Tan"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Faculty of Medicine, University Malaya, Jalan Profesor Diraja Ungku Aziz, Kuala Lumpur, 50603, Malaysia.",
            "firstname": "Saniyati Badri",
            "initials": "SB",
            "lastname": "Bashirudin"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Faculty of Medicine, University Malaya, Jalan Profesor Diraja Ungku Aziz, Kuala Lumpur, 50603, Malaysia.",
            "firstname": "Rajeev Kumar",
            "initials": "RK",
            "lastname": "Rajaratnam"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Faculty of Medicine, University Malaya, Jalan Profesor Diraja Ungku Aziz, Kuala Lumpur, 50603, Malaysia. farah.faizg@ummc.edu.my.",
            "firstname": "Farah",
            "initials": "F",
            "lastname": "Gan"
        }
    ],
    "conclusions": "Shorter women and IOLAC by vaginal dinoprostone compared to Foley balloon were independently predictive of composite of adverse outcome.",
    "copyrights": "\u00a9 2024. The Author(s).\n\u00a9 2024. The Author(s).",
    "doi": "10.1186/s12884-024-06650-5\n10.1067/mob.2000.109037\n10.1371/journal.pone.0237132\n10.1056/nejm200107053450101\n10.1097/AOG.0000000000003079\n10.1002/ijgo.14364\n10.1002/ijgo.14166\n10.1007/s00404-015-3715-0\n10.1097/aog.0000000000003622\n10.1007/s43032-022-00906-1\n10.1111/j.1471-0528.1971.tb00329.x\n10.1093/humrep/des365\n10.1016/j.ajog.2009.06.014\n10.1097/AOG.0b013e3181d992fb\n10.1016/s0029-7844(00)01129-7\n10.3109/00016348509155137\n10.1111/j.1447-0756.2010.01476.x\n10.1111/j.1447-0756.1989.tb00170.x\n10.1016/0020-7292(85)90027-x\n10.1111/1471-0528.13015\n10.1056/NEJMoa040405\n10.1016/j.ajog.2004.02.035\n10.1016/s0002-9378(99)70049-9\n10.1016/s0029-7844(97)00553-x\n10.1016/s0301-2115(03)00363-4\n10.1016/0020-7292(95)02431-b\n10.1067/mob.2001.110293\n10.1111/aogs.14211\n10.1016/j.ajog.2012.06.028\n10.1002/ijgo.15178\n10.1016/j.ajog.2006.06.042\n10.1186/s12884-019-2517-y\n10.1097/aog.0000000000002351\n10.1111/aogs.13565\n10.1016/0895-4356(95)00048-8\n10.1186/s12874-016-0267-3\n10.1016/j.eurox.2023.100249\n10.1002/ijgo.14318\n10.1111/1471-0528.13015\n10.1016/S0140-6736(22)01845-1\n10.1186/s12884-019-2687-7\n10.1177/0018726714532856\n10.1111/aogs.14425\n10.1136/bmj.e2838",
    "journal": "BMC pregnancy and childbirth",
    "keywords": [
        "Dinoprostone",
        "Emergency cesarean",
        "Foley",
        "Labor induction",
        "Predictor",
        "Previous cesarean"
    ],
    "methods": null,
    "publication_date": "2024-07-02",
    "pubmed_id": "38951754\n34130991\n11084562\n32764773\n11439945\n30681536\n35869955\n35245946\n25864097\n5805538\n31809438\n20230321\n35246823\n5558856\n34259491\n23081871\n27780708\n19733288\n20410775\n11165577\n4024880\n21481086\n2757575\n7432723\n2866120\n21804498\n25088680\n15598960\n15167874\n10368501\n9572178\n15036710\n7589750\n11262462\n34114644\n22749410\n37818982\n17000247\n31623587\n28937571\n30737767\n8543964\n27881078\n37860619\n35751576\n25088680\n33103511\n36366885\n31888530\n35920107\n22577197",
    "results": "Electronic medical records of 19,064 women were screened. 819 IOLAC cases and 98 cases with composite adverse outcomes were identified. Maternal height, ethnicity, previous vaginal delivery, indication of previous cesarean, indication for IOLAC, and method of IOLAC had p\u2009<\u20090.10 on bivariate analysis and were incorporated into a multivariable binary logistic regression analysis. After adjustment, only maternal height and IOLAC by vaginal dinoprostone compared to Foley balloon remained significant at p\u2009<\u20090.05. Post hoc adjusted analysis that included all unplanned cesarean as an added qualifier for composite adverse outcome showed higher body mass index, short stature (<\u2009157\u00a0cm), not of Chinese ethnicity, no prior vaginal delivery, prior cesarean indicated by labor dystocia, and less favorable Bishop score (<\u20096) were independent predictors of the expanded composite adverse outcome.",
    "title": "Short stature and vaginal dinoprostone as independent predictors of composite maternal-newborn adverse outcomes in induction of labor after one previous cesarean: a retrospective cohort study.",
    "xml": "<Element 'PubmedArticle' at 0x788503700090>"
}