{
    "abstract": "Atazanavir is an antiretroviral medication used to treat and prevent HIV/AIDS, but its effects on cardiac fibrosis are unknown. The aim of this study was to determine the effects of atazanavir on myocardial infarction (MI)-induced cardiac fibrosis in rats and used a TLR 9 antagonist, hydroxychloroquine (HCQ) to elucidate the potential mechanism in vitro. The results indicated that atazanavir significantly attenuated CoCl",
    "authors": [
        {
            "affiliation": "School of Pharmacy, Binzhou Medical University, Yantai 264003, PR China.",
            "firstname": "Guanghua",
            "initials": "G",
            "lastname": "Zhang"
        },
        {
            "affiliation": "School of Pharmacy, Binzhou Medical University, Yantai 264003, PR China.",
            "firstname": "Xue",
            "initials": "X",
            "lastname": "Zhang"
        },
        {
            "affiliation": "School of Pharmacy, Binzhou Medical University, Yantai 264003, PR China.",
            "firstname": "Defang",
            "initials": "D",
            "lastname": "Li"
        },
        {
            "affiliation": "School of Pharmacy, Yantai University, Yantai 264003, PR China.",
            "firstname": "Jingwei",
            "initials": "J",
            "lastname": "Tian"
        },
        {
            "affiliation": "School of Pharmacy, Binzhou Medical University, Yantai 264003, PR China. Electronic address: jwl518@163.com.",
            "firstname": "Wanglin",
            "initials": "W",
            "lastname": "Jiang"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright \u00a9 2018 Elsevier B.V. All rights reserved.",
    "doi": "10.1016/j.ejphar.2018.03.041",
    "journal": "European journal of pharmacology",
    "keywords": [
        "Atazanavir",
        "High mobility group box-1 protein",
        "Myocardial infarction",
        "Toll-like receptor 9"
    ],
    "methods": null,
    "publication_date": "2018-04-02",
    "pubmed_id": "29605419",
    "results": null,
    "title": "Long-term oral atazanavir attenuates myocardial infarction-induced cardiac fibrosis.",
    "xml": "<Element 'PubmedArticle' at 0x78850276e7a0>"
}