{
    "abstract": "The value of Forrester's perfusion/congestion profiles assessed by invasive catheter evaluation in non-inotrope advanced heart failure patients listed for heart transplant (HT) is unclear. We aimed to assess the value of haemodynamic evaluation according to Forrester's profiles to predict events on the HT waitlist.\nAll non-inotrope patients (n\u00a0=\u00a0837, 79% ambulatory at listing) registered on the French national HT waiting list between 1 January 2013 and 31 December 2019 with right heart catheterization (RHC) were included. The primary outcome was a combined criteria of waitlist death, delisting for aggravation, urgent HT or left ventricular assist device implantation. Secondary outcome was waitlist death. The 'warm-dry', 'cold-dry', 'warm-wet', and 'cold-wet' profiles represented 27%, 18%, 27%, and 28% of patients, respectively. At 12\u00a0months, the respective rates of primary outcome were 15%, 17%, 25%, and 29% (P\u00a0=\u00a00.008). Taking the 'warm-dry' category as reference, a significant increase in the risk of primary outcome was observed only in the 'wet' categories, irrespectively of 'warm/cold' status: hazard ratios, 1.50; 1.06-2.13; P\u00a0=\u00a00.024 in 'warm-wet' and 1.77; 1. 25-2.49; P\u00a0=\u00a00.001 in 'cold-wet'.\nHaemodynamic assessment of advanced HF patients using perfusion/congestion profiles predicts the risk of the combine endpoint of waitlist death, delisting for aggravation, urgent heart transplantation, or left ventricular assist device implantation. 'Wet' patients had the worst prognosis, independently of perfusion status, thus placing special emphasis on the cardinal prominence of persistent congestion in advanced HF.",
    "authors": [
        {
            "affiliation": "Department of heart failure and transplantation, H\u00f4pital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon, 69500, Bron, France.\nCentre d'Investigations Cliniques Plurith\u00e9matique 1433, INSERM DCAC, CHRU de Nancy, F-CRIN INI-CRCT, Universit\u00e9 de Lorraine, 54500, Vandoeuvre-l\u00e8s-Nancy, Nancy, France.",
            "firstname": "Guillaume",
            "initials": "G",
            "lastname": "Baudry"
        },
        {
            "affiliation": "Department of Cardiac and Thoracic Surgery, Cardiology Institute, Piti\u00e9 Salp\u00eatri\u00e8re Hospital, Assistance Publique-H\u00f4pitaux de Paris (AP-HP). Sorbonne University Medical School, Paris, France.",
            "firstname": "Guillaume",
            "initials": "G",
            "lastname": "Coutance"
        },
        {
            "affiliation": "Department of Cardiac Surgery, CHU Bichat-Claude Bernard, AP-HP, Universit\u00e9 Paris VII, 75877, Paris, France.",
            "firstname": "Richard",
            "initials": "R",
            "lastname": "Dorent"
        },
        {
            "affiliation": "Department of Cardiology and Cardiovascular Surgery, Hospital Charles Nicolle, Rouen, France.",
            "firstname": "Fabrice",
            "initials": "F",
            "lastname": "Bauer"
        },
        {
            "affiliation": "Department of Cardiology and Cardiac Surgery, University Hospital of Caen, University of Caen, Caen, France.",
            "firstname": "Katrien",
            "initials": "K",
            "lastname": "Blanchart"
        },
        {
            "affiliation": "Department of Cardiology and Cardiovascular Surgery, CHU Michallon, Grenoble, France.",
            "firstname": "Aude",
            "initials": "A",
            "lastname": "Boignard"
        },
        {
            "affiliation": "Department of Thoracic and Cardiovascular Surgery, CHU Pontchaillou, Inserm U1099, 35000, Rennes, France.",
            "firstname": "C\u00e9line",
            "initials": "C",
            "lastname": "Chabanne"
        },
        {
            "affiliation": "Department of Cardiology, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.",
            "firstname": "Cl\u00e9ment",
            "initials": "C",
            "lastname": "Delmas"
        },
        {
            "affiliation": "Cardiology and Cardiac Surgery Department, CHU Clermont-Ferrand, Clermont-Ferrand, France.",
            "firstname": "Nicolas",
            "initials": "N",
            "lastname": "D'Ostrevy"
        },
        {
            "affiliation": "Department of Cardiology and Cardiovascular Surgery, H\u00f4pitaux Universitaires de Strasbourg, Strasbourg, France.",
            "firstname": "Eric",
            "initials": "E",
            "lastname": "Epailly"
        },
        {
            "affiliation": "Department of Cardiac Surgery, La Timone Hospital, Marseille, France.",
            "firstname": "Vlad",
            "initials": "V",
            "lastname": "Gariboldi"
        },
        {
            "affiliation": "Department of Cardiac Surgery, Anesthesiology and Critical Care Medicine, Arnaud de Villeneuve Hospital, CHRU Montpellier, Montpellier, France.",
            "firstname": "Philippe",
            "initials": "P",
            "lastname": "Gaudard"
        },
        {
            "affiliation": "Department of Cardiac Surgery, CHU Lille, Institut Coeur Poumons, Lille, France.",
            "firstname": "C\u00e9line",
            "initials": "C",
            "lastname": "Go\u00e9minne"
        },
        {
            "affiliation": "Department of Cardiology and Cardiac Surgery, University Hospital of Dijon, Dijon, France.",
            "firstname": "Sandrine",
            "initials": "S",
            "lastname": "Grosjean"
        },
        {
            "affiliation": "Department of Cardiothoracic Surgery, Marie Lannelongue Hospital, University of Paris Sud, Inserm U999 [Pulmonary Hypertension: Pathophysiology and Novel Therapies (PAH)], 92350, Le Plessis Robinson, France.",
            "firstname": "Julien",
            "initials": "J",
            "lastname": "Guihaire"
        },
        {
            "affiliation": "Cardiology and Cardiac Surgery Department, European Georges Pompidou Hospital, Paris, France.",
            "firstname": "Romain",
            "initials": "R",
            "lastname": "Guillemain"
        },
        {
            "affiliation": "Department of Cardiology and Cardiac Surgery, CHU de Nancy, Hopital de Brabois, Nancy, France.",
            "firstname": "Mathieu",
            "initials": "M",
            "lastname": "Mattei"
        },
        {
            "affiliation": "Department of Thoracic and Cardiovascular Surgery, H\u00f4pital Cardiologique du Haut-L\u00e9v\u00eaque, Universit\u00e9 Bordeaux II, Bordeaux, France.",
            "firstname": "Karine",
            "initials": "K",
            "lastname": "Nubret"
        },
        {
            "affiliation": "Department of Cardiology and Heart Transplantation Unit, CHU de Nantes, Nantes, France.",
            "firstname": "Sabine",
            "initials": "S",
            "lastname": "Pattier"
        },
        {
            "affiliation": "Department of heart failure and transplantation, H\u00f4pital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon, 69500, Bron, France.",
            "firstname": "Matteo",
            "initials": "M",
            "lastname": "Pozzi"
        },
        {
            "affiliation": "Centre d'Investigations Cliniques Plurith\u00e9matique 1433, INSERM DCAC, CHRU de Nancy, F-CRIN INI-CRCT, Universit\u00e9 de Lorraine, 54500, Vandoeuvre-l\u00e8s-Nancy, Nancy, France.",
            "firstname": "Patrick",
            "initials": "P",
            "lastname": "Rossignol"
        },
        {
            "affiliation": "Cardiothoracic Surgery Department, Tours University Hospital, Tours, France.",
            "firstname": "Emmanuelle",
            "initials": "E",
            "lastname": "Vermes"
        },
        {
            "affiliation": "Department of heart failure and transplantation, H\u00f4pital Cardiovasculaire Louis Pradel, Hospices Civils de Lyon, 69500, Bron, France.",
            "firstname": "Laurent",
            "initials": "L",
            "lastname": "Sebbag"
        },
        {
            "affiliation": "Centre d'Investigations Cliniques Plurith\u00e9matique 1433, INSERM DCAC, CHRU de Nancy, F-CRIN INI-CRCT, Universit\u00e9 de Lorraine, 54500, Vandoeuvre-l\u00e8s-Nancy, Nancy, France.",
            "firstname": "Nicolas",
            "initials": "N",
            "lastname": "Girerd"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.",
    "doi": "10.1002/ehf2.14037",
    "journal": "ESC heart failure",
    "keywords": [
        "Advanced heart failure",
        "Cardiac oedema",
        "Cardiovascular diseases",
        "Forrester's classification",
        "Heart transplant"
    ],
    "methods": null,
    "publication_date": "2022-07-09",
    "pubmed_id": "35801277\n0\n27220672\n790194\n790191\n32037718\n28272288\n12767667\n27894487\n31127678\n11420761\n31442494\n23293303\n2244566\n26703245\n8109553\n31652650\n12885733\n26179184\n24920349\n29806100\n9193435\n22795401\n28465311\n23095984\n33118672\n26417699\n30718133\n31667987\n26560249\n34461042\n27819111\n26693947\n29141174\n30600580\n31838029\n30843353",
    "results": null,
    "title": "Prognosis value of Forrester's classification in advanced heart failure patients awaiting heart transplantation.",
    "xml": "<Element 'PubmedArticle' at 0x788503a54950>"
}