{
    "abstract": "This study aimed to evaluate the impact of detailed cochlear dimensions, assessed using micro-CT (\u00b5CT) imaging, on insertion outcomes and associated trauma with a new slim, precurved electrode array.\nEleven temporal bone specimens underwent implantation of a 22-electrode slim precurved array via the round window. High-resolution \u00b5CT scans post-implantation enabled visualization of cochlear structures and electrode positioning. Combination with subsequent scans taken after electrodes removal, we analyzed angular insertion depth (AID), insertion length, number of electrodes inserted, cochlear dimensions (specifically cochlear duct length (CDL), basal turn diameter, scala tympani dimension), and intracochlear trauma of fine structures. Statistical analyses were performed to correlate cochlear detailed dimensions and morphology with insertion outcomes and trauma.\nThe mean AID was 351.82\u00b0, and the mean insertion length was 21.07\u00a0mm. CDL showed positive correlations with AID and insertion length. Basal turn diameter (value B) positively correlated with AID and insertion length, unlike value A. Middle-basal turn (M/B) relationships (angle and height) significantly influenced insertion depth. The cochleae with smaller M/B heights and specific angles were more susceptible to insertion trauma. Larger basal turn diameters correlated with increased trauma and electrode translocation into the scala vestibuli.\nThis study highlights the importance of precise cochlear measurements in predicting and optimizing cochlear implant outcomes. Specific cochlear dimensions and anatomical shapes were identified as critical factors affecting insertion depth, trauma risk, and electrode positioning. Utilizing micro-CT provided detailed insights into cochlear anatomy and insertion outcomes, offering valuable data for advancing cochlear implant technology and surgical practices.",
    "authors": [
        {
            "affiliation": "ENT Institute and Department of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 20031, China.\nNHC Key Laboratory of Hearing Medicine Research, Fudan University, Shanghai, 20031, China.",
            "firstname": "Jiabao",
            "initials": "J",
            "lastname": "Mao"
        },
        {
            "affiliation": "ENT Institute and Department of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 20031, China.\nNHC Key Laboratory of Hearing Medicine Research, Fudan University, Shanghai, 20031, China.",
            "firstname": "Linhan",
            "initials": "L",
            "lastname": "Huang"
        },
        {
            "affiliation": "ENT Institute and Department of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 20031, China.\nNHC Key Laboratory of Hearing Medicine Research, Fudan University, Shanghai, 20031, China.",
            "firstname": "Zhangcai",
            "initials": "Z",
            "lastname": "Chi"
        },
        {
            "affiliation": "ENT Institute and Department of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 20031, China.\nNHC Key Laboratory of Hearing Medicine Research, Fudan University, Shanghai, 20031, China.",
            "firstname": "Min",
            "initials": "M",
            "lastname": "Chen"
        },
        {
            "affiliation": "ENT Institute and Department of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 20031, China.\nNHC Key Laboratory of Hearing Medicine Research, Fudan University, Shanghai, 20031, China.",
            "firstname": "Wen",
            "initials": "W",
            "lastname": "Li"
        },
        {
            "affiliation": "ENT Institute and Department of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 20031, China. lisf@fudan.edu.cn.\nNHC Key Laboratory of Hearing Medicine Research, Fudan University, Shanghai, 20031, China. lisf@fudan.edu.cn.",
            "firstname": "Shufeng",
            "initials": "S",
            "lastname": "Li"
        }
    ],
    "conclusions": "This study highlights the importance of precise cochlear measurements in predicting and optimizing cochlear implant outcomes. Specific cochlear dimensions and anatomical shapes were identified as critical factors affecting insertion depth, trauma risk, and electrode positioning. Utilizing micro-CT provided detailed insights into cochlear anatomy and insertion outcomes, offering valuable data for advancing cochlear implant technology and surgical practices.",
    "copyrights": "\u00a9 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",
    "doi": "10.1007/s00405-024-09058-1\n10.1097/mao.0b013e318184f492\n10.3109/14992027.2013.854413\n10.1016/j.heares.2015.08.018\n10.1097/moo.0000000000000742\n10.1007/s00405-017-4842-y\n10.1097/mao.0000000000000211\n10.1016/j.mri.2012.05.001\n10.1007/s00276-015-1469-9\n10.1007/s00405-013-2448-6\n10.1097/mao.0b013e3182255915\n10.1080/00016480500437377\n10.1007/s00405-022-07811-y\n10.1002/ar.23730\n10.1097/mao.0000000000003337\n10.1097/mao.0000000000002298\n10.1097/mao.0000000000001125\n10.1016/j.anorl.2016.05.001\n10.1371/journal.pone.0206435\n10.1097/mao.0000000000003731\n10.1097/01.aud.0000436256.06395.63\n10.1038/s41598-023-47133-5\n10.1007/s00330-021-08189-x\n10.1097/mao.0000000000003956\n10.1007/s00405-023-08064-z\n10.3109/14992027.2013.802032\n10.3109/00016489.2010.544327\n10.1097/01.mlg.0000157695.07536.d2\n10.1016/j.heares.2016.06.015\n10.1097/mao.0000000000003402\n10.1097/aud.0b013e3182741aa7\n10.1097/mao.0000000000002460\n10.3174/ajnr.a4189\n10.1097/mao.0b013e3181d27b5e\n10.1097/mao.0b013e3181a32c0d\n10.1080/00016489.2021.1897159\n10.1016/j.joto.2019.01.002\n10.1002/lary.29224",
    "journal": "European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery",
    "keywords": [
        "Angular insertion depth, AID",
        "Cochlear duct length",
        "Cochlear implantation",
        "Cochlear morphology",
        "Insertion trauma",
        "Micro-computed tomography,\u00a0\u00b5CT"
    ],
    "methods": null,
    "publication_date": "2024-11-03",
    "pubmed_id": "39488599\n18667935\n24304359\n26341474\n34354014\n29242990\n24335932\n22770690\n25929238\n23536136\n21725264\n16698695\n36604323\n29160929\n34538852\n31135680\n27348391\n27246743\n30365565\n36351223\n24196418\n34463797\n37550888\n37466660\n23992489\n21281057\n15867642\n27371868\n35015749\n23348845\n31789806\n25430856\n20142798\n19415036\n33784954\n31467506\n33159469",
    "results": "The mean AID was 351.82\u00b0, and the mean insertion length was 21.07\u00a0mm. CDL showed positive correlations with AID and insertion length. Basal turn diameter (value B) positively correlated with AID and insertion length, unlike value A. Middle-basal turn (M/B) relationships (angle and height) significantly influenced insertion depth. The cochleae with smaller M/B heights and specific angles were more susceptible to insertion trauma. Larger basal turn diameters correlated with increased trauma and electrode translocation into the scala vestibuli.",
    "title": "Impact of cochlear detailed morphology on insertion results and intracochlear trauma of a slim pre-curved electrode array: a micro-CT study.",
    "xml": "<Element 'PubmedArticle' at 0x788504aae660>"
}