{
    "abstract": "To optimize channel configurations for a flexible ureteroscope incorporating both irrigation and suction channels, in vitro experiments were conducted with the aim of achieving safer and more efficient surgical procedures. Upper urinary tract models with integrated pressure-sensing ports were constructed based on CT urography reconstructions. Functional ureteroscope prototypes with various combinations of infusion and suction channel diameters were developed. Using a controlled constant-pressure irrigation system, intrarenal pressure measurements were obtained from the upper, middle, and lower calyces, as well as the renal pelvis. The effects of varying infusion pressures on irrigation flow rates and intrarenal pressure distribution were assessed. Regression models were subsequently established for renal pelvic pressure (RPP) and irrigation flow rate, allowing for the determination of the optimal channel diameter configuration by integrating model predictions with clinical requirements. At an infusion pressure of 500 cmH",
    "authors": [
        {
            "affiliation": "Department of Urology, The First Affiliated Hospital of Ningbo University, 59#, Liuting Street, Haishu District, Ningbo, 315000, Zhejiang, China.\nDepartment of Biochemistry, Zhejiang University School of Medicine, Hangzhou, China.",
            "firstname": "Fengqi",
            "initials": "F",
            "lastname": "Wang"
        },
        {
            "affiliation": "Department of Urology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.",
            "firstname": "Yanqi",
            "initials": "Y",
            "lastname": "Xie"
        },
        {
            "affiliation": "Department of Urology, The First Affiliated Hospital of Ningbo University, 59#, Liuting Street, Haishu District, Ningbo, 315000, Zhejiang, China.\nNingbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, 315300, Zhejiang, China.",
            "firstname": "Baiyang",
            "initials": "B",
            "lastname": "Song"
        },
        {
            "affiliation": "Department of Urology, The First Affiliated Hospital of Ningbo University, 59#, Liuting Street, Haishu District, Ningbo, 315000, Zhejiang, China.",
            "firstname": "Wanzhang",
            "initials": "W",
            "lastname": "Liu"
        },
        {
            "affiliation": "Department of Urology, The First Affiliated Hospital of Ningbo University, 59#, Liuting Street, Haishu District, Ningbo, 315000, Zhejiang, China.",
            "firstname": "Ting",
            "initials": "T",
            "lastname": "Huang"
        },
        {
            "affiliation": "Department of Anesthesiology and Pain Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.",
            "firstname": "Zhengyi",
            "initials": "Z",
            "lastname": "Wang"
        },
        {
            "affiliation": "Department of Urology, Jiaxing Hospital of Traditonal Chinese Medicine, Jiaxing, China.",
            "firstname": "Pengfei",
            "initials": "P",
            "lastname": "Qin"
        },
        {
            "affiliation": "Department of Urology, Shangyu People's Hospital, Shaoxing, China.",
            "firstname": "Dan",
            "initials": "D",
            "lastname": "Jin"
        },
        {
            "affiliation": "Department of Urology, The First Affiliated Hospital of Ningbo University, 59#, Liuting Street, Haishu District, Ningbo, 315000, Zhejiang, China.",
            "firstname": "Yingzhi",
            "initials": "Y",
            "lastname": "Chen"
        },
        {
            "affiliation": "Department of Urology, The First Affiliated Hospital of Ningbo University, 59#, Liuting Street, Haishu District, Ningbo, 315000, Zhejiang, China. fyyfangli@nbu.edu.cn.\nZhejiang Engineering Research Center of Innovative Technologies and Diagnostic and Therapeutic Equipment for Urinary System Diseases, Hangzhou, China. fyyfangli@nbu.edu.cn.",
            "firstname": "Li",
            "initials": "L",
            "lastname": "Fang"
        },
        {
            "affiliation": "Department of Urology, The First Affiliated Hospital of Ningbo University, 59#, Liuting Street, Haishu District, Ningbo, 315000, Zhejiang, China. fyychengyue@nbu.edu.cn.\nZhejiang Engineering Research Center of Innovative Technologies and Diagnostic and Therapeutic Equipment for Urinary System Diseases, Hangzhou, China. fyychengyue@nbu.edu.cn.",
            "firstname": "Yue",
            "initials": "Y",
            "lastname": "Cheng"
        }
    ],
    "conclusions": null,
    "copyrights": "\u00a9 2025. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",
    "doi": "10.1007/s00240-025-01756-7\n10.1016/j.ajur.2018.08.007\n10.1016/j.eururo.2017.10.033\n10.1111/bju.15836\n10.1186/s12894-024-01644-z\n10.7759/cureus.76256\n10.1177/17562872251314809\n10.1016/j.acuroe.2023.06.001\n10.1016/j.juro.2012.08.197\n10.1007/s00345-015-1582-8\n10.1002/ctd2.70031\n10.1089/end.2018.0774\n10.1007/s00345-024-04815-7\n10.1016/j.urology.2021.04.024\n10.1016/j.eclinm.2024.102724\n10.1007/s00240-023-01430-w\n10.1089/end.2015.0770\n10.1007/s00345-024-04794-9\n10.1089/end.2022.0216\n10.1016/j.ajur.2023.02.002",
    "journal": "Urolithiasis",
    "keywords": [
        "Design",
        "Flexible ureteroscope",
        "Hydrodynamics",
        "Renal pelvic pressure"
    ],
    "methods": null,
    "publication_date": "2025-04-26",
    "pubmed_id": "40285912\n30364478\n29137830\n35733358\n39736616\n39845241\n39896048\n37302691\n22982421\n25971204\n30595058\n38453696\n33961891\n39070176\n36929459\n27558001\n38460016\n35793107\n37538159",
    "results": null,
    "title": "Optimizing infusion-suction diameter ratio (ISDR) in ureteroscopy: in vitro pressure and flow prediction and management.",
    "xml": "<Element 'PubmedArticle' at 0x788506e5cbd0>"
}