{
    "abstract": "Disseminated intravascular coagulation (DIC) is a life-threatening event during resuscitation. The International Society on Thrombosis and Haemostasis (ISTH) diagnostic scoring system enables early diagnosis of DIC. We here report three clinical cases of DIC characterized by several etiologies: prostatic adenocarcinoma, septic shock and retroplacental hematoma. The tests of hemostasis needed to calculate international society on thrombosis and haemostasis (ISTH) score (platelet count, prothrombin ratio, values of fibrinogen and D-dimer levels) were performed regularly. Additional, complementary tests (soluble complexes test, euglobulin lysis test, antithrombin level dosing, activated protein C and factor V dosing) were also performed. ISTH score enables early diagnosis of DIC.\nLa coagulation intravasculaire diss\u00e9min\u00e9e (CIVD) est une cause de mortalit\u00e9 redoutable en milieu de r\u00e9animation. L\u00b4utilisation du syst\u00e8me de score de la soci\u00e9t\u00e9 internationale sur la thrombose et l\u00b4h\u00e9mostase (ISTH) permet de faciliter le diagnostic pr\u00e9coce de la CIVD. Nous pr\u00e9sentons trois observations cliniques de CIVD d\u00b4\u00e9tiologies diff\u00e9rentes: un ad\u00e9nocarcinome prostatique, un choc septique et un h\u00e9matome r\u00e9tro-placentaire. Les tests d\u00b4h\u00e9mostase n\u00e9cessaires au calcul du score de la Soci\u00e9t\u00e9 Internationale sur la Thrombose et l\u00b4H\u00e9mostase (ISTH) (num\u00e9ration plaquettaire, taux de prothrombine, fibrinog\u00e8ne et D-dim\u00e8res) ont \u00e9t\u00e9 r\u00e9guli\u00e8rement r\u00e9alis\u00e9s. D\u00b4autres tests compl\u00e9mentaires (recherche de complexes solubles, test de lyse des euglobulines, dosage des taux d\u00b4antithrombine, de prot\u00e9ine C activ\u00e9e et du facteur V) ont \u00e9t\u00e9 \u00e9galement r\u00e9alis\u00e9s. L\u00b4utilisation du score ISTH permet de faciliter le diagnostic pr\u00e9coce de la CIVD.",
    "authors": [
        {
            "affiliation": "Laboratoire d\u00b4H\u00e9matologie, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Sawsen",
            "initials": "S",
            "lastname": "Bouzidi"
        },
        {
            "affiliation": "Service d\u00b4Anesth\u00e9sie R\u00e9animation, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Mayssa",
            "initials": "M",
            "lastname": "Daiki"
        },
        {
            "affiliation": "Laboratoire d\u00b4H\u00e9matologie, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Amen Allah",
            "initials": "AA",
            "lastname": "Nasr"
        },
        {
            "affiliation": "Laboratoire d\u00b4H\u00e9matologie, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Kaouther",
            "initials": "K",
            "lastname": "Nsiri"
        },
        {
            "affiliation": "Unit\u00e9 de Recherche de Biologie Mol\u00e9culaire (UR17DN06), Laboratoire d\u00b4H\u00e9matologie, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Samy",
            "initials": "S",
            "lastname": "Layouni"
        },
        {
            "affiliation": "Service d\u00b4Anesth\u00e9sie R\u00e9animation, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Zied",
            "initials": "Z",
            "lastname": "Hajjej"
        },
        {
            "affiliation": "Unit\u00e9 de Recherche de Biologie Mol\u00e9culaire (UR17DN06), Laboratoire d\u00b4H\u00e9matologie, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Najiba",
            "initials": "N",
            "lastname": "Fekih-Mrissa"
        },
        {
            "affiliation": "Service d\u00b4Anesth\u00e9sie R\u00e9animation, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Mustapha",
            "initials": "M",
            "lastname": "Ferjani"
        },
        {
            "affiliation": "Laboratoire d\u00b4H\u00e9matologie, H\u00f4pital Militaire Principal d\u00b4Instruction de Tunis, Tunis, Tunisie.",
            "firstname": "Brahim",
            "initials": "B",
            "lastname": "Nsiri"
        }
    ],
    "conclusions": null,
    "copyrights": "Copyright: Sawsen Bouzidi et al.\nCopyright: Sawsen Bouzidi et al.",
    "doi": "10.11604/pamj.2020.36.154.20368",
    "journal": "The Pan African medical journal",
    "keywords": [
        "Disseminated intravascular coagulation",
        "international society on thrombosis and haemostasis",
        "score"
    ],
    "methods": null,
    "publication_date": "2020-09-03",
    "pubmed_id": "32874418\n20950905\n11816725\n19222477\n24750668\n18342149\n19285272\n23130841\n25556711\n27803823\n29255070\n15025782\n20614389\n31304023\n27250996\n24557707\n29202320",
    "results": null,
    "title": "[Disseminated intravascular coagulation: role of the International Society on Thrombosis and Haemostasis (ISTH) diagnostic scoring system].",
    "xml": "<Element 'PubmedArticle' at 0x78850707d2b0>"
}