{
    "abstract": "Baclofen is a gamma- aminobutyric acid B (GABA B) agonist used for the management of spasticity associated with spinal cord injury. Oral baclofen might cause constipation, but intestinal pseudo-obstruction is very rare. We report a 50-year-old male with spasticity following cervical discectomy (C3-4) on oral baclofen for 6 months with intestinal pseudo-obstruction. He had undergone open suprapubic cystostomy for traumatic urethral injury, 45 days prior to the presentation and adhesive intestinal obstruction was also considered a possibility. However, there were no air fluid levels on abdominal radiographs and ultrasound abdomen was non-contributory. Withdrawal of baclofen was therapeutic in this patient. This case is being reported to highlight the rare possibility of oral baclofen induced intestinal pseudo-obstruction.",
    "authors": [
        {
            "affiliation": "Department of General Surgery, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India.",
            "firstname": "Vilvapathy Senguttuvan",
            "initials": "VS",
            "lastname": "Karthikeyan"
        },
        {
            "affiliation": "Department of General Surgery, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India.",
            "firstname": "Kuppusamy",
            "initials": "K",
            "lastname": "Senthilkumaran"
        },
        {
            "affiliation": "Department of General Surgery, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India.",
            "firstname": "Bettaiyagowder",
            "initials": "B",
            "lastname": "Easwaran"
        },
        {
            "affiliation": "Department of Neurosurgery, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India.",
            "firstname": "Rajamariappan",
            "initials": "R",
            "lastname": "Rajbhaskar"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.4103/0976-500X.162010",
    "journal": "Journal of pharmacology & pharmacotherapeutics",
    "keywords": [
        "Adynamic obstruction",
        "baclofen",
        "constipation",
        "intestinal pseudo-obstruction",
        "spasticity"
    ],
    "methods": null,
    "publication_date": "2015-08-28",
    "pubmed_id": "26312004\n15479666\n15880314\n17378237\n18552496\n12217208\n19010351\n200069\n7477521\n21414101\n12217208\n21712934",
    "results": null,
    "title": "Intestinal pseudo-obstruction following oral baclofen: An unusual complication.",
    "xml": "<Element 'PubmedArticle' at 0x788505eb8950>"
}