{
    "abstract": "We report the results of a randomized, double-blind comparison of short-term versus long-term cefoxitin prophylaxis against infections after radical abdominal hysterectomy with pelvic and para-aortic lymphadenectomy. Of 113 evaluable patients, 54 (47.8%) received short-term (three doses) and 59 (52.2%) long-term (12 doses) prophylaxis with intravenous cefoxitin (2 g per dose). No significant differences in demographics, preoperative risk factors, or clinical course were detected between the two groups; nor did we detect significant differences in the incidence of surgical-site-related infections (7.4 versus 5.1%, respectively, P = .61), postoperative urinary tract infection, or other febrile morbidity. We conclude that short-term and long-term cefoxitin prophylaxis are equally effective for the prevention of post-operative surgical-site-related infections after radical hysterectomy.",
    "authors": [
        {
            "affiliation": "Department of Obstetrics and Gynecology, University of Miami School of Medicine, Florida.",
            "firstname": "B U",
            "initials": "BU",
            "lastname": "Sevin"
        },
        {
            "affiliation": null,
            "firstname": "R",
            "initials": "R",
            "lastname": "Ramos"
        },
        {
            "affiliation": null,
            "firstname": "R T",
            "initials": "RT",
            "lastname": "Gerhardt"
        },
        {
            "affiliation": null,
            "firstname": "L",
            "initials": "L",
            "lastname": "Guerra"
        },
        {
            "affiliation": null,
            "firstname": "S",
            "initials": "S",
            "lastname": "Hilsenbeck"
        },
        {
            "affiliation": null,
            "firstname": "H E",
            "initials": "HE",
            "lastname": "Averette"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": null,
    "journal": "Obstetrics and gynecology",
    "keywords": [],
    "methods": null,
    "publication_date": "1991-05-01",
    "pubmed_id": "2014087",
    "results": null,
    "title": "Comparative efficacy of short-term versus long-term cefoxitin prophylaxis against postoperative infection after radical hysterectomy: a prospective study.",
    "xml": "<Element 'PubmedArticle' at 0x7885030bfba0>"
}