{
    "abstract": "For safe management of cell-free and concentrated ascites reinfusion therapy (CART), a highly reliable leak test for detecting ascites filter damage is essential. However, such a test has not been established for drop-type CART.\nWe devised two novel leak tests for drop- and external pressure-type CART, manual or pump pressurization methods, using high-pressure loading and pressure monitoring, and investigated their reliability.\nBoth methods could easily load and maintain sufficiently high pressure (>400\u2009Torr) on the hollow fibers for 2\u2009min. No result deviation was noted between different operators. The pressure drops in both methods were identical and significantly lower than those in the leak test using a special CART machine, the e-CART.\nThe reliability of our revised leak test is equivalent to that of the automatic leak test of e-CART. These highly reliable leak tests may contribute to safety in patients undergoing drop- and external pressure-type CART.",
    "authors": [
        {
            "affiliation": "Department of Clinical Engineering, Shinshu University Hospital, Matsumoto, Nagano, Japan.\nDivision of Blood Purification, Shinshu University Hospital, Matsumoto, Nagano, Japan.",
            "firstname": "Yasuko",
            "initials": "Y",
            "lastname": "Kobayashi"
        },
        {
            "affiliation": "Department of Clinical Engineering, Shinshu University Hospital, Matsumoto, Nagano, Japan.\nDivision of Blood Purification, Shinshu University Hospital, Matsumoto, Nagano, Japan.",
            "firstname": "Nana",
            "initials": "N",
            "lastname": "Ozawa"
        },
        {
            "affiliation": "Department of Clinical Engineering, Shinshu University Hospital, Matsumoto, Nagano, Japan.\nDivision of Blood Purification, Shinshu University Hospital, Matsumoto, Nagano, Japan.",
            "firstname": "Tamami",
            "initials": "T",
            "lastname": "Yoshida"
        },
        {
            "affiliation": "Department of Clinical Engineering, Shinshu University Hospital, Matsumoto, Nagano, Japan.\nDivision of Blood Purification, Shinshu University Hospital, Matsumoto, Nagano, Japan.",
            "firstname": "Takashi",
            "initials": "T",
            "lastname": "Minowa"
        },
        {
            "affiliation": "Department of Clinical Engineering, Shinshu University Hospital, Matsumoto, Nagano, Japan.",
            "firstname": "Yuki",
            "initials": "Y",
            "lastname": "Michinaga"
        },
        {
            "affiliation": "Division of Blood Purification, Shinshu University Hospital, Matsumoto, Nagano, Japan.\nDepartment of Nephrology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.",
            "firstname": "Keita",
            "initials": "K",
            "lastname": "Inui"
        },
        {
            "affiliation": "Department of Nephrology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.",
            "firstname": "Koji",
            "initials": "K",
            "lastname": "Hashimoto"
        },
        {
            "affiliation": "Division of Blood Purification, Shinshu University Hospital, Matsumoto, Nagano, Japan.\nDepartment of Nephrology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.",
            "firstname": "Yuji",
            "initials": "Y",
            "lastname": "Kamijo"
        }
    ],
    "conclusions": "The reliability of our revised leak test is equivalent to that of the automatic leak test of e-CART. These highly reliable leak tests may contribute to safety in patients undergoing drop- and external pressure-type CART.",
    "copyrights": "\u00a9 2023 The Authors. Therapeutic Apheresis and Dialysis published by John Wiley & Sons Australia, Ltd on behalf of International Society for Apheresis and Japanese Society for Apheresis.",
    "doi": "10.1111/1744-9987.14048",
    "journal": "Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy",
    "keywords": [
        "drop-type CART",
        "external pressure",
        "leak test",
        "pressure loading",
        "pressure monitoring"
    ],
    "methods": null,
    "publication_date": "2023-08-18",
    "pubmed_id": "37594000",
    "results": "Both methods could easily load and maintain sufficiently high pressure (>400\u2009Torr) on the hollow fibers for 2\u2009min. No result deviation was noted between different operators. The pressure drops in both methods were identical and significantly lower than those in the leak test using a special CART machine, the e-CART.",
    "title": "Novel and highly reliable leak check tests for drop- and external pressure-type cell-free and concentrated ascites reinfusion therapy.",
    "xml": "<Element 'PubmedArticle' at 0x78850456eed0>"
}