{
    "abstract": "",
    "authors": [
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Dieter",
            "initials": "D",
            "lastname": "Mielke"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Marina",
            "initials": "M",
            "lastname": "Tuyishime"
        },
        {
            "affiliation": "Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, NH 03756, USA.",
            "firstname": "Natasha S",
            "initials": "NS",
            "lastname": "Kelkar"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.",
            "firstname": "Yunfei",
            "initials": "Y",
            "lastname": "Wang"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.",
            "firstname": "Robert",
            "initials": "R",
            "lastname": "Parks"
        },
        {
            "affiliation": "Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.",
            "firstname": "Sampa",
            "initials": "S",
            "lastname": "Santra"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.",
            "firstname": "Wes",
            "initials": "W",
            "lastname": "Rountree"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "LaTonya D",
            "initials": "LD",
            "lastname": "Williams"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Tiffany",
            "initials": "T",
            "lastname": "Peters"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Nathan",
            "initials": "N",
            "lastname": "Eisel"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Sheetal",
            "initials": "S",
            "lastname": "Sawant"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Lu",
            "initials": "L",
            "lastname": "Zhang"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Derrick",
            "initials": "D",
            "lastname": "Goodman"
        },
        {
            "affiliation": "Department of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Shalini",
            "initials": "S",
            "lastname": "Jha"
        },
        {
            "affiliation": "Department of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Adam",
            "initials": "A",
            "lastname": "Zalaquett"
        },
        {
            "affiliation": "Department of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Pratamesh",
            "initials": "P",
            "lastname": "Ramasubramanian"
        },
        {
            "affiliation": "Department of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Sherry",
            "initials": "S",
            "lastname": "Stanfield-Oakley"
        },
        {
            "affiliation": "U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.",
            "firstname": "Gary",
            "initials": "G",
            "lastname": "Matyas"
        },
        {
            "affiliation": "U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.",
            "firstname": "Zoltan",
            "initials": "Z",
            "lastname": "Beck"
        },
        {
            "affiliation": "U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.",
            "firstname": "Mangala",
            "initials": "M",
            "lastname": "Rao"
        },
        {
            "affiliation": "U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.",
            "firstname": "Julie",
            "initials": "J",
            "lastname": "Ake"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.",
            "firstname": "Thomas N",
            "initials": "TN",
            "lastname": "Denny"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "David C",
            "initials": "DC",
            "lastname": "Montefiori"
        },
        {
            "affiliation": "Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, NH 03756, USA.\nThayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.",
            "firstname": "Margaret E",
            "initials": "ME",
            "lastname": "Ackerman"
        },
        {
            "affiliation": "Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98104, USA.",
            "firstname": "Lawrence",
            "initials": "L",
            "lastname": "Corey"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.\nDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.\nDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.",
            "firstname": "Georgia D",
            "initials": "GD",
            "lastname": "Tomaras"
        },
        {
            "affiliation": "T-6: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.\nNew Mexico Consortium, Los Alamos, NM 87545, USA.",
            "firstname": "Bette T",
            "initials": "BT",
            "lastname": "Korber"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.",
            "firstname": "Barton F",
            "initials": "BF",
            "lastname": "Haynes"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.",
            "firstname": "Xiaoying",
            "initials": "X",
            "lastname": "Shen"
        },
        {
            "affiliation": "Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.\nDuke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.\nDepartment of Surgery, Duke University, Durham, NC 27710, USA.\nDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.",
            "firstname": "Guido",
            "initials": "G",
            "lastname": "Ferrari"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.3390/vaccines13030231\n10.1056/NEJMoa0908492\n10.1056/NEJMoa1113425\n10.1126/scitranslmed.3007730\n10.1056/NEJMoa2031499\n10.1016/S1473-3099(24)00358-X\n10.1093/infdis/jiac260\n10.1016/j.ebiom.2024.105320\n10.1038/ncomms15711\n10.3390/vaccines13020133\n10.1016/S2352-3018(18)30071-7\n10.1016/j.virol.2006.04.043\n10.1371/journal.ppat.1005042\n10.1128/JVI.01708-08\n10.1002/cyto.a.21084\n10.1182/blood.V90.3.1109\n10.1016/j.jim.2010.12.016\n10.1371/journal.ppat.1005817\n10.1128/JVI.00383-15\n10.1016/j.jim.2013.11.022\n10.1128/JVI.02108-09\n10.1038/s41591-018-0161-0\n10.15252/msb.20188747\n10.1002/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4\n10.1128/JVI.01843-17\n10.1038/nature11519\n10.1016/j.immuni.2012.11.011\n10.1016/j.celrep.2020.107624\n10.1128/JVI.05045-11",
    "journal": "Vaccines",
    "keywords": [
        "HIV-1",
        "correlate of protection",
        "subtype C",
        "systems serology",
        "variable loops 1 and 2"
    ],
    "methods": null,
    "publication_date": "2025-04-23",
    "pubmed_id": "40266065\n19843557\n22475592\n24648342\n33761206\n39038477\n35758878\n39236556\n28593989\n40006680\n29898870\n17039602\n26237403\n18842730\n21735545\n9242542\n21192942\n27579713\n25855741\n24291345\n19939925\n30177821\n31048360\n8668867\n29386288\n22960785\n23313589\n32402293\n21795340",
    "results": null,
    "title": "Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge.",
    "xml": "<Element 'PubmedArticle' at 0x7885042f84f0>"
}