{
    "abstract": "To estimate the incidence of and define risk factors for postpartum infectious complications after vaginal birth after cesarean (VBAC) complicated by chorioamnionitis.\nA secondary analysis of the \nA total of 559 subjects had chorioamnionitis in labor and a successful VBAC. Twenty-four (4.3%) subjects experienced the primary outcome, mainly due to endometritis (19/24). Significant factors included preterm delivery <32 weeks (odds ratio [OR]: 3.05, 95% confidence interval [CI]: 1.32-7.06) and body mass index (BMI) \u226540 (OR: 4.63, 95% CI: 1.25-17.14). Receipt of postpartum antibiotics was protective against postpartum infection (OR: 0.28, 95% CI: 0.12-0.65). In multivariate analysis, preterm delivery <32 weeks, BMI \u226540, and receipt of postpartum antibiotics remained associated with postpartum infection.\nNearly 5% of women with chorioamnionitis had a postpartum infectious complication after vaginal delivery, with higher rates in those delivering at <32 weeks and with prepregnancy BMI \u226540. Receipt of postpartum antibiotics decreased the odds of postpartum infection markedly.",
    "authors": [
        {
            "affiliation": "Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.",
            "firstname": "Anna E",
            "initials": "AE",
            "lastname": "DeNoble"
        },
        {
            "affiliation": "Department of Obstetrics and Gynecology, Wake Forest Baptist Health, Winston-Salem, North Carolina.",
            "firstname": "R Phillips",
            "initials": "RP",
            "lastname": "Heine"
        },
        {
            "affiliation": "Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.",
            "firstname": "Sarah K",
            "initials": "SK",
            "lastname": "Dotters-Katz"
        }
    ],
    "conclusions": "Nearly 5% of women with chorioamnionitis had a postpartum infectious complication after vaginal delivery, with higher rates in those delivering at <32 weeks and with prepregnancy BMI \u226540. Receipt of postpartum antibiotics decreased the odds of postpartum infection markedly.",
    "copyrights": "Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.",
    "doi": "10.1055/s-0039-1692718",
    "journal": "American journal of perinatology",
    "keywords": [],
    "methods": null,
    "publication_date": "2019-06-27",
    "pubmed_id": "31238347",
    "results": "A total of 559 subjects had chorioamnionitis in labor and a successful VBAC. Twenty-four (4.3%) subjects experienced the primary outcome, mainly due to endometritis (19/24). Significant factors included preterm delivery <32 weeks (odds ratio [OR]: 3.05, 95% confidence interval [CI]: 1.32-7.06) and body mass index (BMI) \u226540 (OR: 4.63, 95% CI: 1.25-17.14). Receipt of postpartum antibiotics was protective against postpartum infection (OR: 0.28, 95% CI: 0.12-0.65). In multivariate analysis, preterm delivery <32 weeks, BMI \u226540, and receipt of postpartum antibiotics remained associated with postpartum infection.",
    "title": "Chorioamnionitis and Infectious Complications after Vaginal Delivery.",
    "xml": "<Element 'PubmedArticle' at 0x7885070ab600>"
}