{
    "abstract": "This review examines the peer-reviewed literature describing prospective studies that report amenorrhea rates, patient satisfaction, and surgical reintervention rates following the NovaSure\u00ae endometrial ablation procedure. A search of the English-language literature published from 2000 to 2011 was conducted using PubMed. Ten prospective studies, six single-arm NovaSure trials, and four randomized controlled trials comparing the NovaSure procedure with other global endometrial ablation modalities met the inclusion criteria and were reviewed. The follow-up periods ranged from 6 to 60 months. Amenorrhea rates for the NovaSure procedure ranged from 30.0% to 75.0%. Patients who reported being satisfied with the NovaSure procedure ranged from 85.0% to 94.0%. In randomized controlled trials with other global endometrial ablation modalities, amenorrhea rates at 12 months with the NovaSure procedure ranged from 43.0% to 56.0%, while other modalities ranged from 8% to 24%. In addition, this manuscript reviews the following: the NovaSure technology; use of the NovaSure procedure in the office setting; intraoperative and postoperative pain; effects on premenstrual syndrome (PMS); dysmenorrhea; special circumstances, including presence of uterine disease, history of cesarean delivery, coagulopathy, or use of anticoagulant medication; post-procedure uterine cavity assessment and cancer risk; contraception and pregnancy; and safety.",
    "authors": [
        {
            "affiliation": "Mercy Clinic, Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Mercy Hospital St Louis, St Louis, MO, USA.",
            "firstname": "Richard J",
            "initials": "RJ",
            "lastname": "Gimpelson"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.2147/IJWH.S56364",
    "journal": "International journal of women's health",
    "keywords": [
        "NovaSure\u00ae",
        "abnormal uterine bleeding",
        "endometrial ablation",
        "menorrhagia"
    ],
    "methods": null,
    "publication_date": "2014-03-22",
    "pubmed_id": "24648771\n22914421\n12206928\n16769073\n0\n21281033\n20677480\n12386350\n18303511\n21507403\n16100642\n12580843\n17218236\n15547528\n17694962\n12101323\n15383112\n17617188\n21705927\n12849825\n20859144\n22105257\n22529302\n12732777\n21872168\n19603322\n16962534\n21907960\n20093876\n20308858\n17540811\n20060089\n15701191\n19294397\n9757952\n21545966\n16527708\n14662215\n17630160\n22996104\n19384149\n17630156\n7794852\n9422012",
    "results": null,
    "title": "Ten-year literature review of global endometrial ablation with the NovaSure\u00ae device.",
    "xml": "<Element 'PubmedArticle' at 0x7885056dc540>"
}