{
    "abstract": "Physiological-based cord clamping (PBCC) led to a more stable cardiovascular adaptation and better oxygenation in preterm lambs, but in preterm infants, this approach has been challenging. Our aim was to assess the feasibility of PBCC, including patterns of oxygen saturation (SpO\nObservational study.\nTertiary referral centre, Leiden University Medical Centre, The Netherlands.\nInfants born below 35 weeks' gestational age.\nInfants were stabilised on a new purpose-built resuscitation table (Concord), provided with standard equipment needed for stabilisation. Cord clamping was performed when the infant was stable (HR >100\u2009bpm, spontaneous breathing on continuous positive airway pressure with tidal volumes >4\u2009mL/kg, SpO\nThirty-seven preterm infants were included; mean (SD) gestational age of 30.9 (2.4) weeks, birth weight 1580 (519) g. PBCC was successful in 33 infants (89.2%) and resulted in median (IQR) cord clamping time of 4:23 (3:00-5:11) min after birth. There were no maternal or neonatal adverse events. In 26/37 infants, measurements were adequate for analysis. HR was 113 (81-143) and 144 (129-155) bpm at 1 min and 5\u2009min after birth. SpO\nPBCC in preterm infants using the Concord is feasible. HR remained stable, and SpO\nNTR6095, results.",
    "authors": [
        {
            "affiliation": "Division of Neonatology, Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands.",
            "firstname": "Emma",
            "initials": "E",
            "lastname": "Brouwer"
        },
        {
            "affiliation": "Division of Neonatology, Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands.\nDivision of Neonatology, Department of Paediatrics, Erasmus University Medical Centre, Rotterdam, The Netherlands.",
            "firstname": "Ronny",
            "initials": "R",
            "lastname": "Knol"
        },
        {
            "affiliation": "Department of Medical Engineering, Leiden University Medical Centre, Leiden, The Netherlands.",
            "firstname": "Alex S N",
            "initials": "ASN",
            "lastname": "Vernooij"
        },
        {
            "affiliation": "Department of Obstetrics, Leiden University Medical Centre, Leiden, The Netherlands.",
            "firstname": "Thomas",
            "initials": "T",
            "lastname": "van den Akker"
        },
        {
            "affiliation": "Division of Neonatology, Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands.",
            "firstname": "Patricia E",
            "initials": "PE",
            "lastname": "Vlasman"
        },
        {
            "affiliation": "Department of Obstetrics, Leiden University Medical Centre, Leiden, The Netherlands.",
            "firstname": "Frans J C M",
            "initials": "FJCM",
            "lastname": "Klumper"
        },
        {
            "affiliation": "Department of Obstetrics and Gynaecology, Erasmus University Medical Centre, Rotterdam, The Netherlands.\nThe Ritchie Centre, Hudson Institute of Medical Research, Monash University, Clayton, Victoria, Australia.",
            "firstname": "Philip",
            "initials": "P",
            "lastname": "DeKoninck"
        },
        {
            "affiliation": "The Ritchie Centre, Hudson Institute of Medical Research, Monash University, Clayton, Victoria, Australia.",
            "firstname": "Graeme R",
            "initials": "GR",
            "lastname": "Polglase"
        },
        {
            "affiliation": "The Ritchie Centre, Hudson Institute of Medical Research, Monash University, Clayton, Victoria, Australia.",
            "firstname": "Stuart B",
            "initials": "SB",
            "lastname": "Hooper"
        },
        {
            "affiliation": "Division of Neonatology, Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands.",
            "firstname": "Arjan B",
            "initials": "AB",
            "lastname": "Te Pas"
        }
    ],
    "conclusions": "PBCC in preterm infants using the Concord is feasible. HR remained stable, and SpO",
    "copyrights": "\u00a9 Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",
    "doi": "10.1136/archdischild-2018-315483\n10.1016/j.ajog.2017.10.231\n10.1002/14651858.CD003248.pub3\n10.1038/jp.2016.151\n10.1113/jphysiol.2012.250084\n10.1371/journal.pone.0117504\n10.1136/archdischild-2017-314005\n10.1136/archdischild-2015-310311\n10.1016/j.resuscitation.2013.01.025\n10.1038/pr.2014.40\n10.1136/archdischild-2016-312567\n10.1016/j.jpeds.2016.07.053\n10.1055/s-0036-1584521\n10.1016/j.resuscitation.2015.07.029\n10.1136/adc.2009.169102\n10.1016/j.jpeds.2016.11.014\n10.1136/archdischild-2016-312366\n10.1136/archdischild-2017-313864\n10.1113/JP270926\n10.1152/japplphysiol.01358.2013\n10.1113/jphysiol.2009.174870\n10.1186/s40748-016-0032-y\n10.1016/j.siny.2018.07.002\n10.1056/NEJMoa1711281\n10.1542/peds.2005-1706\n10.1038/sj.jp.7210970\n10.1016/j.jpeds.2014.09.015\n10.1016/j.jpeds.2008.01.002\n10.1542/peds.2009-1510",
    "journal": "Archives of disease in childhood. Fetal and neonatal edition",
    "keywords": [
        "circulatory",
        "neonatology",
        "physiology",
        "respiratory",
        "resuscitation"
    ],
    "methods": null,
    "publication_date": "2018-10-05",
    "pubmed_id": "30282674\n29097178\n22895933\n27654493\n23401615\n25689406\n29208663\n28302696\n23376585\n27939259\n24614803\n28923985\n27574999\n27305177\n26477415\n4186454\n20444810\n13872354\n27939259\n28988158\n29353261\n26278276\n24994883\n19675069\n27298730\n30001819\n23843134\n29081267\n16585320\n13679933\n25444526\n18492509\n20439604",
    "results": "Thirty-seven preterm infants were included; mean (SD) gestational age of 30.9 (2.4) weeks, birth weight 1580 (519) g. PBCC was successful in 33 infants (89.2%) and resulted in median (IQR) cord clamping time of 4:23 (3:00-5:11) min after birth. There were no maternal or neonatal adverse events. In 26/37 infants, measurements were adequate for analysis. HR was 113 (81-143) and 144 (129-155) bpm at 1 min and 5\u2009min after birth. SpO",
    "title": "Physiological-based cord clamping in preterm infants using a new purpose-built resuscitation table: a feasibility study.",
    "xml": "<Element 'PubmedArticle' at 0x7885045e5580>"
}