{
    "abstract": "Fournier's gangrene (FG) describes necrotizing infections of the perineum in both sexes. Controversies in treatment of FG include the roles of orchiectomy, urinary and/or fecal diversion, and hyperbaric oxygen (HBO). Because burn centers often treat these patients, we reviewed our experience with FG during a 14-year period. With Institutional Review Board approval, we reviewed our TRACS/ABA database for patients treated for FG during 1992 to 2005. Data was recorded on demographics, preexisting medical conditions, treatment, and outcomes. Thirty patients (20 men) were identified. Mean age was 54.3 +/- 14.1 years. Predisposing conditions included diabetes in 16 patients (53%), and morbid obesity and immunosuppression in 6 each. Twenty-two patients were transferred from outside hospitals, 12 after initial surgery. Sixteen patients presented with shock (blood pressure <90/60 mm Hg). Patients underwent a mean of 4.1 surgical procedures. Ten infections penetrated the deep fascia of the perineum or abdominal wall. Suprapubic cystostomy was performed in three patients, colostomy in seven, orchiectomy in one. HBO was not used. Hospitalization averaged 25.3 +/- 15.6 days. Mean charges ($1000) were $131.5 +/- 108.3. Definitive wound closure was obtained before discharge with suture repair and/or skin grafting in 18 of 25 survivors (72%). Five patients died (17%). In logistic regression analysis, the presence of shock on admission and female gender (mortality 40%) were significantly associated with mortality. FG remains a devastating infection, which occurs primarily in compromised patients. In this series, aggressive burn center care produced outcomes equivalent to those published in other series with or without use of HBO. Colostomy and urinary diversion can be used very selectively in these patients; orchiectomy is rarely required.",
    "authors": [
        {
            "affiliation": "Department of Surgery, Burn-Trauma Center, University of Utah Health Center, Salt Lake City, Utah 84132, USA.",
            "firstname": "Jeffrey R",
            "initials": "JR",
            "lastname": "Saffle"
        },
        {
            "affiliation": null,
            "firstname": "Stephen E",
            "initials": "SE",
            "lastname": "Morris"
        },
        {
            "affiliation": null,
            "firstname": "Linda",
            "initials": "L",
            "lastname": "Edelman"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.1097/BCR.0b013e318160daba",
    "journal": "Journal of burn care & research : official publication of the American Burn Association",
    "keywords": [],
    "methods": null,
    "publication_date": "2008-01-10",
    "pubmed_id": "18182922",
    "results": null,
    "title": "Fournier's gangrene: management at a regional burn center.",
    "xml": "<Element 'PubmedArticle' at 0x7885048d8310>"
}