{
    "abstract": "",
    "authors": [
        {
            "affiliation": "Laboratory of Engineering Electrochemistry, Modeling, and Environment, Department of Chemistry, Faculty of Sciences Dhar Mahraz, Sidi Mohamed Ben Abdellah University, Fez 30000, Morocco.",
            "firstname": "Oussama",
            "initials": "O",
            "lastname": "Merzouki"
        },
        {
            "affiliation": "School of Science and Engineering, Al Akhawayn University in Ifrane, Hassan II Avenue, Ifrane 53000, Morocco.",
            "firstname": "Nadia",
            "initials": "N",
            "lastname": "Arrousse"
        },
        {
            "affiliation": "Laboratory of Physics and Chemistry of Inorganic and Organic Materials, Higher Normal School, Mohammed V University, Rabat 30050, Morocco.",
            "firstname": "Elhachmia",
            "initials": "E",
            "lastname": "Ech-Chihbi"
        },
        {
            "affiliation": "Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia.",
            "firstname": "Ashwag S",
            "initials": "AS",
            "lastname": "Alanazi"
        },
        {
            "affiliation": "Laboratory of Engineering Electrochemistry, Modeling, and Environment, Department of Chemistry, Faculty of Sciences Dhar Mahraz, Sidi Mohamed Ben Abdellah University, Fez 30000, Morocco.\nLaboratory of Materials Engineering for the Environment and Natural Ressources, Faculty of Sciences and Technics, University of Moulay Ismail, Meknes, B.P 509, Boutalamine, Errachidia 52000, Morocco.",
            "firstname": "El Houssine",
            "initials": "EH",
            "lastname": "Mabrouk"
        },
        {
            "affiliation": "Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.",
            "firstname": "Mohamed",
            "initials": "M",
            "lastname": "Hefnawy"
        },
        {
            "affiliation": "Plant Biotechnology Team, Faculty of Sciences, Abdelmalek Essaadi University, Tetouan 93002, Morocco.\nLaboratory of Biotechnology, Environment, Agrifood, and Health, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez 30050, Morocco.",
            "firstname": "Abdelfattah",
            "initials": "A",
            "lastname": "El Moussaoui"
        },
        {
            "affiliation": "Laboratory of Biotechnology, Environment, Agrifood, and Health, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez 30050, Morocco.",
            "firstname": "Hanane",
            "initials": "H",
            "lastname": "Touijer"
        },
        {
            "affiliation": "Laboratory of Biotechnology, Environment, Agrifood, and Health, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez 30050, Morocco.",
            "firstname": "Azeddin",
            "initials": "A",
            "lastname": "El Barnossi"
        },
        {
            "affiliation": "Laboratory of Engineering Electrochemistry, Modeling, and Environment, Department of Chemistry, Faculty of Sciences Dhar Mahraz, Sidi Mohamed Ben Abdellah University, Fez 30000, Morocco.",
            "firstname": "Mustapha",
            "initials": "M",
            "lastname": "Taleb"
        }
    ],
    "conclusions": null,
    "copyrights": null,
    "doi": "10.3390/ph18020167\n10.1007/s13738-020-01873-7\n10.1016/j.ejmech.2017.07.059\n10.3390/molecules25061364\n10.1016/j.bioorg.2019.103470\n10.3390/molecules28145359\n10.1016/j.molstruc.2021.131977\n10.1002/ardp.201700223\n10.1016/j.ejmech.2014.03.033\n10.1002/ardp.202000077\n10.1016/j.ejmech.2009.03.038\n10.1016/j.jsps.2024.102025\n10.1016/j.sjbs.2015.07.005\n10.3390/ijms24097834\n10.1016/j.ejmcr.2022.100042\n10.2174/1389557519666190313095545\n10.1016/j.heliyon.2020.e03185\n10.1007/s00044-015-1467-9\n10.1016/j.emcon.2024.100389\n10.1093/jac/dkaa161\n10.1016/j.molstruc.2024.140169\n10.1016/j.molstruc.2024.140474\n10.1093/cid/cix411\n10.3390/antiox9090852\n10.1016/j.bpobgyn.2010.10.016\n10.1042/BJ20101695\n10.2174/1570178617666200108111211\n10.1016/j.molstruc.2024.140265\n10.1016/j.molstruc.2023.136771\n10.1016/j.molstruc.2024.140558\n10.1080/10406638.2023.2254896\n10.1016/j.ejmech.2018.07.007\n10.1016/j.freeradbiomed.2011.09.032\n10.1016/j.ejmech.2011.01.060\n10.1016/j.ejmech.2023.115548\n10.1016/j.molstruc.2023.136760\n10.1016/j.molstruc.2023.135780\n10.1016/j.bmc.2017.09.035\n10.1016/j.molstruc.2022.133966\n10.1007/s11095-005-8476-1\n10.1016/j.compbiomed.2020.103936\n10.3389/fphar.2019.00434\n10.17344/acsi.2020.5985\n10.1038/nsb1196-951\n10.3390/molecules28145340\n10.1016/j.rechem.2023.100996\n10.1080/07391102.2024.2305313\n10.1016/j.bioorg.2021.104696\n10.1021/jp020715j\n10.48317/IMIST.PRSM/morjchem-v4i2.4509\n10.1016/j.molstruc.2022.133424\n10.1016/j.foodchem.2008.06.026\n10.1006/abio.1996.0292\n10.1016/j.jpha.2015.11.005\n10.1051/e3sconf/202015002003\n10.1155/2022/6305672\n10.1016/j.ymeth.2007.01.006\n10.3390/life12101553\n10.1016/j.heliyon.2023.e13402\n10.1016/j.molstruc.2021.132240\n10.1038/srep42717\n10.1093/nar/gkab255\n10.1016/j.ygeno.2020.12.015\n10.1016/j.compstruc.2015.05.017\n10.1021/acs.jmedchem.5b00104\n10.1016/j.aichem.2023.100020\n10.1002/jcc.21334\n10.1109/SC.2014.9",
    "journal": "Pharmaceuticals (Basel, Switzerland)",
    "keywords": [
        "ADMET",
        "medicinal activities",
        "molecular docking",
        "pyrazole derivatives",
        "synthesis"
    ],
    "methods": null,
    "publication_date": "2025-02-26",
    "pubmed_id": "40005981\n28818767\n32192149\n32120072\n37513232\n29400412\n24681068\n32484273\n19419804\n38550332\n27579011\n37175540\n30864524\n31956713\n32417924\n28472416\n32927924\n21130690\n21309749\n30015075\n22036835\n21342734\n37307623\n28988624\n16308672\n32738628\n31068821\n34738130\n8901874\n37513216\n38247233\n33652343\n8660627\n29403965\n36204116\n17560319\n36294988\n36820032\n28256516\n33893803\n33321204\n25860834\n19499576",
    "results": null,
    "title": "Environmentally Friendly Synthesis of New Mono- and Bis-Pyrazole Derivatives; In Vitro Antimicrobial, Antifungal, and Antioxidant Activity; and In Silico Studies: DFT, ADMETox, and Molecular Docking.",
    "xml": "<Element 'PubmedArticle' at 0x788504c76610>"
}