{
    "abstract": "Different research groups reported a negative correlation between cancers and parasitical infections. As an example, the prevalence of a hydatid cyst among patients with cancer was significantly lower than its prevalence among normal population. Tn antigens exist both in cancer and hydatid cyst. This common antigen may be involved in the effect of parasite on cancer growth. So in this work, common antigens between hydatid cyst and cancers have been investigated.\nDifferent hydatid cyst antigens including hydatid fluid, laminated and germinal layer antigens, and excretory secretory antigens of protoscolices were run in SDS PAGE and transferred to NCP paper. In western immunoblotting, those antigens were probed with sera of patients with different cancer and also sera of non-cancer patients. Also, cross reaction among excretory secretory products of cancer cells and antisera raised against different hydatid cyst antigen was investigated.\nIn western immunoblotting, antisera raised against laminated and germinal layers of hydatid cyst reacted with excretory secretory products of cancer cells. Also, a reaction was detected between hydatid cyst antigens and sera of patients with some cancers.\nResults of this work emphasize existence of common antigens between hydatid cyst and cancers. More investigation about these common antigens is recommended.",
    "authors": [
        {
            "affiliation": "Department of Parasitology and Mycology, Isfahan University of Medical Sciences, Isfahan, Iran.",
            "firstname": "Shima",
            "initials": "S",
            "lastname": "Daneshpour"
        },
        {
            "affiliation": "Department of Parasitology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.",
            "firstname": "Mehran",
            "initials": "M",
            "lastname": "Bahadoran"
        },
        {
            "affiliation": "Department of Parasitology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.",
            "firstname": "Seyed Hossein",
            "initials": "SH",
            "lastname": "Hejazi"
        },
        {
            "affiliation": "Department of Parasitology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.",
            "firstname": "Abas Ali",
            "initials": "AA",
            "lastname": "Eskandarian"
        },
        {
            "affiliation": "Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.",
            "firstname": "Mehdi",
            "initials": "M",
            "lastname": "Mahmoudzadeh"
        },
        {
            "affiliation": "Department of Parasitology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.",
            "firstname": "Hossein Yousofi",
            "initials": "HY",
            "lastname": "Darani"
        }
    ],
    "conclusions": "Results of this work emphasize existence of common antigens between hydatid cyst and cancers. More investigation about these common antigens is recommended.",
    "copyrights": null,
    "doi": "10.4103/2277-9175.175242",
    "journal": "Advanced biomedical research",
    "keywords": [
        "Cancer",
        "common antigen",
        "hydatid cyst"
    ],
    "methods": null,
    "publication_date": "2016-03-11",
    "pubmed_id": "26962511\n14584087\n8980372\n23231515\n17415440\n18368713\n17290901\n11433940\n9660468\n12717523\n19039942\n5127071\n17923753\n1558892\n1606251\n20585536\n3971344\n3734844\n19488426\n8402581\n21931708\n18477891\n22496957\n11465993\n3597358\n15270554\n14678327\n17300782\n14533679\n12547345\n16393356\n9353421\n16033538\n23231515\n5432063\n6424787",
    "results": "In western immunoblotting, antisera raised against laminated and germinal layers of hydatid cyst reacted with excretory secretory products of cancer cells. Also, a reaction was detected between hydatid cyst antigens and sera of patients with some cancers.",
    "title": "Common antigens between hydatid cyst and cancers.",
    "xml": "<Element 'PubmedArticle' at 0x7885045e4d60>"
}